Frontiers in Genetics | Cancer Genetics and Oncogenomics

Original Research

Accepted on 13 Feb 2026

Exploring prognostic genes related to lactylation and programmed cell death in pancreatic ductal adenocarcinoma: a comprehensive study combining bulk transcriptomics and experimental verification

in Cancer Genetics and Oncogenomics

Jiaoyu Ai
Boxing Zhang
Gen Sun
Luying Huang
Wenjun Wei
Yuzhang Yuan
Zehua Wang
Xingzhou Peng
Liang Song
Kıvanç Görgülü

Frontiers in Genetics

Original Research

Accepted on 12 Feb 2026

Mutant p53 and TP53 mutations in esophageal squamous cell carcinoma: consistency and diagnostic significance

in Cancer Genetics and Oncogenomics

Xueyu Zhuang
Na Lin
Yanjuan Xu

Frontiers in Genetics

Mini Review

Accepted on 12 Feb 2026

Long Noncoding RNAs in tumor stemness: Emerging Mechanisms and Therapeutic Opportunities

in Cancer Genetics and Oncogenomics

Eduardo M Reis
Daniela Sanchez Bassères

Frontiers in Genetics

Systematic Review

Published on 12 Feb 2026

The impact of circulating tumor DNA on the prognosis of liver cancer and its predictive value: a meta analysis

in Cancer Genetics and Oncogenomics

Bing Wu
Shuhui Ke
Lingling Zhu
Rongrong Dong
Jinqian Luan

Frontiers in Genetics

doi 10.3389/fgene.2026.1767755

343 views

Brief Research Report

Published on 11 Feb 2026

Genomic innovation in precision oncology: integrated CRISPR-TTP bioengineering architecture for Ewing Sarcoma (version 4.0 – complete architectural specification)

in Cancer Genetics and Oncogenomics

Alexey Mikhailovich Burlai

Frontiers in Genetics

doi 10.3389/fgene.2026.1727708

667 views

Original Research

Accepted on 10 Feb 2026

Comprehensive analyses of biological function and tumor microenvironment with cuproptosis regulators and construction of a cuproptosis-related scoring system in thyroid cancer based on bioinformatics and experimental validation

in Cancer Genetics and Oncogenomics

Shitong Su
Kun Tian
Zijian Liu
Ruijie Liu

Frontiers in Genetics

Original Research

Published on 09 Feb 2026

Clinical significance and oncogenic role of ECHDC2 in glioblastoma: a comprehensive analysis based on bioinformatics and in vitro experiments

in Cancer Genetics and Oncogenomics

Shengliang Lin
Tian Wei
Qian Wu
Qingqing Liu
Longyun Hu
Bigui Song
Jiejing Lin
Zewei Zhao
Yi Cai
Xiaoxiao Li

Frontiers in Genetics

doi 10.3389/fgene.2026.1759463

545 views

Original Research

Accepted on 03 Feb 2026

Construction and validation of a prognostic model for lung adenocarcinoma (LUAD) based on necrotic cell death triggered by sodium overload (NECSO)-related coexpressed genes

in Cancer Genetics and Oncogenomics

Li Liang
Xiaoqi Wang
Huihui Liu
Ting Huang
Quan Zhu
Fangguo Lu
Chunjing Chen

Frontiers in Genetics

119 views

Correction

Published on 30 Jan 2026

Correction: Driver gene alterations in NSCLC patients in southern China and their correlation with clinicopathologic characteristics

in Cancer Genetics and Oncogenomics

Lingna Deng
Jinbang Li
Zhanlong Qiu
Yanfen Wang

Frontiers in Genetics

doi 10.3389/fgene.2026.1794164

562 views

Original Research

Published on 29 Jan 2026

Identification of potentially deleterious mutations in gastric cancer using patient-derived xenograft models

in Cancer Genetics and Oncogenomics

Luke Kong
Jie Wang
Junqi Zheng
Xihua Yang
Ruifang Sun
Jiahui Kou
Yujie Yao
Feng Li
Fuhua Wang
Sutang Guo

Frontiers in Genetics

doi 10.3389/fgene.2025.1571535

750 views

Original Research

Accepted on 28 Jan 2026

Genomic Landscape of Oral Squamous Cell Carcinoma from the Southwest Coast of Karnataka: Insights from FFPE-Based Next-Generation Sequencing

in Cancer Genetics and Oncogenomics

Hafeeda Kunhabdulla
Riaz Abdulla
Divya Lakshmanan Mangalath
Rohan Thomas
Devika Jayarajan
Vipul Jain
Fahizah A
Muhammed S Mustak
Ranajit Das

Frontiers in Genetics

132 views

Original Research

Published on 28 Jan 2026

Differential effects on tumor progression by APOBEC3A, APOBEC3B, and APOBEC3H Haplotype I in a breast cancer mouse xenograft model

in Cancer Genetics and Oncogenomics

Milaid Granadillo Rodríguez
Lai Wong
Arzhang Shayeganmehr
Diogo Pellegrina
Frederick S. Vizeacoumar
Franco J. Vizeacoumar
Mohamed Helmy
Linda Chelico

Frontiers in Genetics

doi 10.3389/fgene.2025.1425483

964 views

Original Research

Accepted on 23 Jan 2026

Differentially Expressed Proteins in Plasma-Derived Extracellular Vesicles from Chronic Myeloid Leukemia Patients

in Cancer Genetics and Oncogenomics

Denise Kusma Wosniaki
Alexandre Luiz Korte de Azevedo
Anelis Marin
Alexis Germán Murillo Carrasco
Luciana N S Andrade
Rodrigo Brant
Michel Batista
Talita Helen Bombardelli Gomig
Roger Chammas
Mateus Aoki

Frontiers in Genetics

225 views

Editorial

Published on 23 Jan 2026

Editorial: Genetics and epigenetics of melanoma and non-melanoma skin cancer

in Cancer Genetics and Oncogenomics

Chiara Moltrasio
Paola Maura Tricarico
Muhammad Suleman
Sergio Crovella
Maurizio Romagnuolo

Frontiers in Genetics

doi 10.3389/fgene.2026.1770737

923 views

Original Research

Published on 21 Jan 2026

CDKN2AIPNL: a potential pan-cancer biomarker

in Cancer Genetics and Oncogenomics

Yulin Yuan
Sheng-Xiao Ma
Heshi Liu
Yang Gong
Xuan Sun
Quan Wang
Weifu Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1588292

1,379 views

Original Research

Published on 20 Jan 2026

Retrospective analysis of preoperative serum tumor marker levels and their correlation with pathological characteristics and prognosis in cervical cancer patients

in Cancer Genetics and Oncogenomics

Yue Shen
Min Kang

Frontiers in Genetics

doi 10.3389/fgene.2026.1724789

684 views

Original Research

Published on 20 Jan 2026

Genome-wide analysis of long non-coding RNAs and mRNAs in lung adenocarcinoma with pulmonary thromboembolism

in Cancer Genetics and Oncogenomics

Maryamgvl Ahmat
Gvzalnur Alim
Zhu Zhu
Chao Chen
Guolei Cao
Qin Luo

Frontiers in Genetics

doi 10.3389/fgene.2025.1683576

832 views

Retraction

Published on 14 Jan 2026

Retraction: Clinical significance of SPOCK2 expression signature for high-grade serous ovarian cancer patients

in Cancer Genetics and Oncogenomics

Frontiers in Genetics

doi 10.3389/fgene.2026.1781969

811 views

Original Research

Published on 12 Jan 2026

Identification of IGF2BP3 and CENPA as key regulators of immunophenotypes in renal clear cell carcinoma

in Cancer Genetics and Oncogenomics

Tianjie Zhu
Liying He
Shuai Li
Jingyuan Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1749780

883 views

Mini Review

Published on 12 Jan 2026

Ribosome plasticity in glioblastoma: a multi-omics framework for future investigation

in Cancer Genetics and Oncogenomics

Dario Benelli
Christian Barbato
Carlo Cogoni

Frontiers in Genetics

doi 10.3389/fgene.2025.1756452

1,043 views
1 citation

Original Research

Published on 08 Jan 2026

Systematic analysis of anoikis-related genes identifies SRPX2-FAK/AKT-IL-6 axis in the progression and peritoneal metastasis of gastric cancer

in Cancer Genetics and Oncogenomics

Dong Hou
Jinhao Yu
Yequan Xie
Shengning Zhou
Jintao Zeng
Mingtao Liang
Fang Zheng
Jianan Tan
Fanghai Han

Frontiers in Genetics

doi 10.3389/fgene.2025.1736097

1,489 views

Original Research

Published on 06 Jan 2026

Integrated network toxicology, machine learning algorithms and TMT proteomics reveal the mechanism of 18β glycyrrhetinic acid against gastric cancer

in Cancer Genetics and Oncogenomics

Doudou Lu
Shumin Jia
Yahong Li
Zhaozhao Wang
Ziying Zhou
Wenjing Liu
Lei Zhang
Ling Yuan
Yi Nan

Frontiers in Genetics

doi 10.3389/fgene.2025.1688077

1,130 views

Mini Review

Published on 05 Jan 2026

Metabolic reprogramming in clear cell renal cell carcinoma: core pathways and targeted therapeutic strategies

in Cancer Genetics and Oncogenomics

MingWei Zhan
BinBin Zhao
Haote Chen
Junjie Wu
Run Shi
Feng Gao
Lin Zhao
Jingyu Zhu

Frontiers in Genetics

doi 10.3389/fgene.2025.1752384

1,568 views

Review

Accepted on 29 Dec 2025

Applications and challenges of multi-omics approaches in lung cancer research and precision treatment

in Cancer Genetics and Oncogenomics

Shouyu Zhang
Jiadi Gan
Qian Zheng
Renjie Xu
Bojiang Chen
Weimin Li

Frontiers in Genetics

178 views

1,195 articles

articles

Exploring prognostic genes related to lactylation and programmed cell death in pancreatic ductal adenocarcinoma: a comprehensive study combining bulk transcriptomics and experimental verification

Mutant p53 and TP53 mutations in esophageal squamous cell carcinoma: consistency and diagnostic significance

Long Noncoding RNAs in tumor stemness: Emerging Mechanisms and Therapeutic Opportunities

The impact of circulating tumor DNA on the prognosis of liver cancer and its predictive value: a meta analysis

Genomic innovation in precision oncology: integrated CRISPR-TTP bioengineering architecture for Ewing Sarcoma (version 4.0 – complete architectural specification)

Comprehensive analyses of biological function and tumor microenvironment with cuproptosis regulators and construction of a cuproptosis-related scoring system in thyroid cancer based on bioinformatics and experimental validation

Clinical significance and oncogenic role of ECHDC2 in glioblastoma: a comprehensive analysis based on bioinformatics and in vitro experiments

Construction and validation of a prognostic model for lung adenocarcinoma (LUAD) based on necrotic cell death triggered by sodium overload (NECSO)-related coexpressed genes

Correction: Driver gene alterations in NSCLC patients in southern China and their correlation with clinicopathologic characteristics

Identification of potentially deleterious mutations in gastric cancer using patient-derived xenograft models

Genomic Landscape of Oral Squamous Cell Carcinoma from the Southwest Coast of Karnataka: Insights from FFPE-Based Next-Generation Sequencing

Differential effects on tumor progression by APOBEC3A, APOBEC3B, and APOBEC3H Haplotype I in a breast cancer mouse xenograft model

Differentially Expressed Proteins in Plasma-Derived Extracellular Vesicles from Chronic Myeloid Leukemia Patients

Editorial: Genetics and epigenetics of melanoma and non-melanoma skin cancer

CDKN2AIPNL: a potential pan-cancer biomarker

Retrospective analysis of preoperative serum tumor marker levels and their correlation with pathological characteristics and prognosis in cervical cancer patients

Genome-wide analysis of long non-coding RNAs and mRNAs in lung adenocarcinoma with pulmonary thromboembolism

Retraction: Clinical significance of SPOCK2 expression signature for high-grade serous ovarian cancer patients

Identification of IGF2BP3 and CENPA as key regulators of immunophenotypes in renal clear cell carcinoma

Ribosome plasticity in glioblastoma: a multi-omics framework for future investigation

Systematic analysis of anoikis-related genes identifies SRPX2-FAK/AKT-IL-6 axis in the progression and peritoneal metastasis of gastric cancer

Integrated network toxicology, machine learning algorithms and TMT proteomics reveal the mechanism of 18β glycyrrhetinic acid against gastric cancer

Metabolic reprogramming in clear cell renal cell carcinoma: core pathways and targeted therapeutic strategies

Applications and challenges of multi-omics approaches in lung cancer research and precision treatment