Frontiers in Genetics | Cancer Genetics and Oncogenomics

Original Research

Accepted on 15 Aug 2025

Identification and validation of three tumor suppressors associated with immune response of acute myeloid leukemia

in Cancer Genetics and Oncogenomics

Yueyuan Pan
Guocai Wu
Chenchen Liu
Minggui Chen
Tian Xia
Yonghua Ma
Ruiting Wen
Zhigang Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1652142

Original Research

Accepted on 15 Aug 2025

Pain -related methylation driver genes affect the prognosis of pancreatic cancer patients by altering immune function and perineural infiltration

in Cancer Genetics and Oncogenomics

Chencheng Zhang
Weiwei Xu
Xudong Chen
Xingdan Wang
Xiaopeng Cui
Wenjing Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1600883

Original Research

Published on 14 Aug 2025

Construction and immunohistochemical validation of a necroptosis-related prognostic signature in bladder cancer and its association with tumor immune infiltration

in Cancer Genetics and Oncogenomics

Tao Wang
Fei Ding
Kai Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1527907

310 views

Original Research

Published on 13 Aug 2025

Integrative multi-omics analysis and machine learning reveal the unique role of ASCC3 in combination with various immune-related genes in rectal adenocarcinoma

in Cancer Genetics and Oncogenomics

Chuang Miao
Fei Qian

Frontiers in Genetics

doi 10.3389/fgene.2025.1614946

464 views

Original Research

Published on 13 Aug 2025

A comprehensive analysis identifies and validates NPC1 as a potential biomarker for prognosis in HCC

in Cancer Genetics and Oncogenomics

Xingjun Lu
Tianyao Gou
Xuxing He
Xia Chen
Daqing Yang
Xiaozhen Peng

Frontiers in Genetics

doi 10.3389/fgene.2025.1588583

380 views

Original Research

Published on 13 Aug 2025

The association between diabetes and head and neck squamous cell carcinoma: evidence from clinical cohort and bioinformatics analyses

in Cancer Genetics and Oncogenomics

Yurong He
Jiaming Chen
Boxuan Han
Yanming Zhao
Lizhen Hou
Jugao Fang
Meng Lian

Frontiers in Genetics

doi 10.3389/fgene.2025.1660012

355 views

Original Research

Accepted on 12 Aug 2025

Identifying Metabolism-Related Genes in Liver Cancer through Weighted Gene Co-expression Network Analysis and Machine Learning

in Cancer Genetics and Oncogenomics

Taorui Wang
Zijun Lai
Shengjun Tang
Lehang Lin
Mingjiao Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1654459

128 views

Editorial

Published on 12 Aug 2025

Editorial: Next generation sequencing and cancer: new steps towards personalized medicine

in Cancer Genetics and Oncogenomics

Erika Bandini
Clévia Rosset

Frontiers in Genetics

doi 10.3389/fgene.2025.1675753

363 views

Methods

Accepted on 11 Aug 2025

Construction of a Novel Prognostic Model for Gastric Cancer Based on Pharmacokinetics-Related Genes and Comprehensive Prognostic Analysis

in Cancer Genetics and Oncogenomics

Yu Zhang
Kai Jia
Yuntong Guo
Ma Xiaole
Tian Yao
Feng Wu
He Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1541401

113 views

Original Research

Accepted on 11 Aug 2025

The Potential Impact of GLS and PDHA1 on Tumor Immunity and Immunotherapy Response in LUSC

in Cancer Genetics and Oncogenomics

Tianhe Ling
WU JIAHUI
LING XIAOHAO

Frontiers in Genetics

doi 10.3389/fgene.2025.1606111

Original Research

Published on 11 Aug 2025

Identification of epithelial-mesenchymal transition prognostic signature associated with prognosis, tumor microenvironment, and therapeutic effect in prostate cancer

in Cancer Genetics and Oncogenomics

Yiyuan Li
Ke Li
Hua Wang
Jianguang Qiu
Chutian Xiao

Frontiers in Genetics

doi 10.3389/fgene.2025.1539745

435 views

Original Research

Published on 11 Aug 2025

Identification and experimental validation of prognostic genes related to cytochrome c in breast cancer

in Cancer Genetics and Oncogenomics

Huimin Yu
Shihong Li
Jian Wu
Haobin Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1627134

397 views

Original Research

Accepted on 08 Aug 2025

Assembly factor for spindle microtubules (ASPM) promotes osimertinib resistance in lung cancer by increasing EGFR stability

in Cancer Genetics and Oncogenomics

Pengpeng Gui
Zhengyi Han
Zhenyu Yin
Peng Cao
Xin Zhou
Yan Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1593314

238 views

Brief Research Report

Published on 06 Aug 2025

Genomic trajectories of colorectal cancer with choroidal metastasis: longitudinal insights from tissue and liquid biopsy via next-generation sequencing

in Cancer Genetics and Oncogenomics

Alessandro Ottaiano
Luisa Circelli
Carmine Picone
Monica Ianniello
Raffaella Ruggiero
Roberto Sirica
Mariachiara Santorsola
Anna Chiara Carratù
Nadia Petrillo
Gaetana Cerbone

Frontiers in Genetics

doi 10.3389/fgene.2025.1632580

480 views

Editorial

Accepted on 05 Aug 2025

Editorial: Emerging Relevance of Molecular Profiling in Global Cancer Research and Management

in Cancer Genetics and Oncogenomics

Premila Leiphrakpam
Srijan Shukla
Chandrakanth Are

Frontiers in Genetics

doi 10.3389/fgene.2025.1679501

178 views

Original Research

Accepted on 05 Aug 2025

Identification of anoikis-related genes to develop a risk model and predict the prognosis and tumor microenvironment in rectal adenocarcinoma Short title: Anoikis Genes Predict Rectal Prognosis

in Cancer Genetics and Oncogenomics

Bing Zhao
Xuegui Tang

Frontiers in Genetics

doi 10.3389/fgene.2025.1604541

127 views