Frontiers in Genetics | Cancer Genetics and Oncogenomics

Methods

Published on 15 Sep 2025

Construction of a novel prognostic model for gastric cancer based on pharmacokinetics-related genes and comprehensive prognostic analysis

in Cancer Genetics and Oncogenomics

Yu Zhang
Kai Jia
Yuntong Guo
Xiaole Ma
Tian Yao
Feng Wu
He Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1541401

1,968 views

Original Research

Published on 09 Sep 2025

Genetic heterogeneity in childhood leukemia/lymphoma: a Turkish cohort with strong predisposition

in Cancer Genetics and Oncogenomics

Gizem Onder
Ozkan Ozdemir
Fulya Taylan
Cengiz Canpolat
Koray Yalcin
Fatih Erbey
Banu Oflaz Sozmen
Fikret Asarcikli
Turan Bayhan
Yunus Murat Akcabelen

Frontiers in Genetics

doi 10.3389/fgene.2025.1624306

3,877 views

Original Research

Published on 09 Sep 2025

ZC3H18 regulates alternative splicing and related genes in cervical cancer

in Cancer Genetics and Oncogenomics

Wenjuan Chen
Chenying Liu
Siyi Li
Xingyun Xie
Dan Hu
Yaobin Lin

Frontiers in Genetics

doi 10.3389/fgene.2025.1621238

2,143 views

Original Research

Published on 08 Sep 2025

A lipid metabolism and lysosome-based risk signature for prognosis and immune response prediction in uterine corpus endometrial carcinoma

in Cancer Genetics and Oncogenomics

Yuanyuan Zhu
Pusheng Yang
Shu Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1594682

2,227 views

Original Research

Published on 05 Sep 2025

Assembly factor for spindle microtubules (ASPM) promotes osimertinib resistance in lung cancer by increasing EGFR stability

in Cancer Genetics and Oncogenomics

Pengpeng Gui
Zhengyi Han
Zhenyu Yin
Peng Cao
Xin Zhou
Yan Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1593314

2,670 views

Brief Research Report

Published on 29 Aug 2025

Identification of oncofetal PIWI-interacting RNAs as potential prognostic biomarkers in non-small cell lung cancer

in Cancer Genetics and Oncogenomics

Michelle E. Pewarchuk
Vanessa G. P. Souza
David E. Cohn
Nikita Telkar
Greg L. Stewart
Katya H. Bénard
Patricia P. Reis
Victor D. Martinez
Wendy P. Robinson
Wan L. Lam

Frontiers in Genetics

doi 10.3389/fgene.2025.1611805

1,875 views

Original Research

Published on 28 Aug 2025

Identification and validation of a histone modification-related gene signature to predict the prognosis of multiple myeloma

in Cancer Genetics and Oncogenomics

Juan Lyu
Shanmei Lyu
Ying Qian
Yi Feng
Zhuan Zheng
Lihong Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1613631

2,018 views

Editorial

Published on 28 Aug 2025

Editorial: Emerging relevance of molecular profiling in global cancer research and management

in Cancer Genetics and Oncogenomics

Premila Leiphrakpam
Srijan Shukla
Chandrakanth Are

Frontiers in Genetics

doi 10.3389/fgene.2025.1679501

1,550 views

Original Research

Published on 25 Aug 2025

VCAM-1 predicts poor prognosis and modulates immune infiltration in gastric cancer: a TCGA-based bioinformatics study

in Cancer Genetics and Oncogenomics

Cheng Wu
Yungeng Liu
Chuanyuan Liu
Chuanfa Fang

Frontiers in Genetics

doi 10.3389/fgene.2025.1602929

2,040 views

Original Research

Published on 18 Aug 2025

The comparison of the prognostic value of different inflammation-related indicators in patients with oral squamous cell carcinoma

in Cancer Genetics and Oncogenomics

Aoming Cheng
Kaixiong Wei
Qiaoshi Xu
Chong Wang
Bo Li
Huan Liu
Lirui Zhang
Hanchen Zhou
Yu Huang
Yiming Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1652603

2,019 views
1 citation

Original Research

Published on 18 Aug 2025

Identification of anoikis-related genes to develop a risk model and predict the prognosis and tumor microenvironment in rectal adenocarcinoma

in Cancer Genetics and Oncogenomics

Bing Zhao
Xuegui Tang

Frontiers in Genetics

doi 10.3389/fgene.2025.1604541

1,962 views

Original Research

Published on 14 Aug 2025

Construction and immunohistochemical validation of a necroptosis-related prognostic signature in bladder cancer and its association with tumor immune infiltration

in Cancer Genetics and Oncogenomics

Tao Wang
Fei Ding
Kai Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1527907

2,644 views

Original Research

Published on 13 Aug 2025

Integrative multi-omics analysis and machine learning reveal the unique role of ASCC3 in combination with various immune-related genes in rectal adenocarcinoma

in Cancer Genetics and Oncogenomics

Chuang Miao
Fei Qian

Frontiers in Genetics

doi 10.3389/fgene.2025.1614946

2,534 views

Original Research

Published on 13 Aug 2025

A comprehensive analysis identifies and validates NPC1 as a potential biomarker for prognosis in HCC

in Cancer Genetics and Oncogenomics

Xingjun Lu
Tianyao Gou
Xuxing He
Xia Chen
Daqing Yang
Xiaozhen Peng

Frontiers in Genetics

doi 10.3389/fgene.2025.1588583

2,043 views

Original Research

Published on 13 Aug 2025

The association between diabetes and head and neck squamous cell carcinoma: evidence from clinical cohort and bioinformatics analyses

in Cancer Genetics and Oncogenomics

Yurong He
Jiaming Chen
Boxuan Han
Yanming Zhao
Lizhen Hou
Jugao Fang
Meng Lian

Frontiers in Genetics

doi 10.3389/fgene.2025.1660012

1,919 views
2 citations

Editorial

Published on 12 Aug 2025

Editorial: Next generation sequencing and cancer: new steps towards personalized medicine

in Cancer Genetics and Oncogenomics

Erika Bandini
Clévia Rosset

Frontiers in Genetics

doi 10.3389/fgene.2025.1675753

2,046 views

Original Research

Published on 11 Aug 2025

Identification and experimental validation of prognostic genes related to cytochrome c in breast cancer

in Cancer Genetics and Oncogenomics

Huimin Yu
Shihong Li
Jian Wu
Haobin Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1627134

2,308 views

Original Research

Published on 11 Aug 2025

Identification of epithelial-mesenchymal transition prognostic signature associated with prognosis, tumor microenvironment, and therapeutic effect in prostate cancer

in Cancer Genetics and Oncogenomics

Yiyuan Li
Ke Li
Hua Wang
Jianguang Qiu
Chutian Xiao

Frontiers in Genetics

doi 10.3389/fgene.2025.1539745

2,401 views
1 citation

Brief Research Report

Published on 06 Aug 2025

Genomic trajectories of colorectal cancer with choroidal metastasis: longitudinal insights from tissue and liquid biopsy via next-generation sequencing

in Cancer Genetics and Oncogenomics

Alessandro Ottaiano
Luisa Circelli
Carmine Picone
Monica Ianniello
Raffaella Ruggiero
Roberto Sirica
Mariachiara Santorsola
Anna Chiara Carratù
Nadia Petrillo
Gaetana Cerbone

Frontiers in Genetics

doi 10.3389/fgene.2025.1632580

2,246 views

Original Research

Published on 30 Jul 2025

Identification and validation of ubiquitination-related genes for predicting cervical cancer outcome

in Cancer Genetics and Oncogenomics

Ge Jin
Xiaomei Fan
Xiaoliang Liang
Honghong Dai
Jun Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1578075

2,890 views

Original Research

Published on 30 Jul 2025

Integrin factor (FAM27E3), as a metastatic marker of papillary thyroid carcinoma, through the p53 signaling pathway promoting lymph node metastasis

in Cancer Genetics and Oncogenomics

Dong Zhang
Kai-Fang Xiang
Chen-Chen Hong
Xiao-Ping Bao
Yan Wu
Rui Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1593553

1,940 views

Systematic Review

Published on 28 Jul 2025

Circulating miRNAs as liquid biopsy biomarkers for diagnosis in patients with colorectal cancer: a systematic review and meta-analysis

in Cancer Genetics and Oncogenomics

Sydney Schwab
Taichiro Nonaka

Frontiers in Genetics

doi 10.3389/fgene.2025.1574586

3,466 views
3 citations

Original Research

Published on 24 Jul 2025

Integrated cytomembrane proteomics identifies EpCAM/MGST1 as therapeutic targets in metastatic laryngeal carcinoma

in Cancer Genetics and Oncogenomics

Suling Zhuang
Xiaobo Wu
Xiaohuang Lin
Zhihan Li
Di Gan
Shixin Wang
Xue Lin
Gongbiao Lin
Miao Gao

Frontiers in Genetics

doi 10.3389/fgene.2025.1615570

2,057 views
1 citation

Original Research

Published on 24 Jul 2025

FEZF1-AS1 drives autophagy-mediated progression of colon cancer and reduces chemosensitivity through inhabiting the PI3K/AKT/mTOR signaling pathway

in Cancer Genetics and Oncogenomics

Xiaoping Yang
Zuohui Yuan
Lingzhu Gou
Long Cheng
Zirui Wang
Pingfan Wu
Xiaochun Wang
Xueni Ma
Tiantian Ma
Yi Yu

Frontiers in Genetics

doi 10.3389/fgene.2025.1514205

2,000 views

1,180 articles

articles

Construction of a novel prognostic model for gastric cancer based on pharmacokinetics-related genes and comprehensive prognostic analysis

Genetic heterogeneity in childhood leukemia/lymphoma: a Turkish cohort with strong predisposition

ZC3H18 regulates alternative splicing and related genes in cervical cancer

A lipid metabolism and lysosome-based risk signature for prognosis and immune response prediction in uterine corpus endometrial carcinoma

Assembly factor for spindle microtubules (ASPM) promotes osimertinib resistance in lung cancer by increasing EGFR stability

Identification of oncofetal PIWI-interacting RNAs as potential prognostic biomarkers in non-small cell lung cancer

Identification and validation of a histone modification-related gene signature to predict the prognosis of multiple myeloma

Editorial: Emerging relevance of molecular profiling in global cancer research and management

VCAM-1 predicts poor prognosis and modulates immune infiltration in gastric cancer: a TCGA-based bioinformatics study

The comparison of the prognostic value of different inflammation-related indicators in patients with oral squamous cell carcinoma

Identification of anoikis-related genes to develop a risk model and predict the prognosis and tumor microenvironment in rectal adenocarcinoma

Construction and immunohistochemical validation of a necroptosis-related prognostic signature in bladder cancer and its association with tumor immune infiltration

Integrative multi-omics analysis and machine learning reveal the unique role of ASCC3 in combination with various immune-related genes in rectal adenocarcinoma

A comprehensive analysis identifies and validates NPC1 as a potential biomarker for prognosis in HCC

The association between diabetes and head and neck squamous cell carcinoma: evidence from clinical cohort and bioinformatics analyses

Editorial: Next generation sequencing and cancer: new steps towards personalized medicine

Identification and experimental validation of prognostic genes related to cytochrome c in breast cancer

Identification of epithelial-mesenchymal transition prognostic signature associated with prognosis, tumor microenvironment, and therapeutic effect in prostate cancer

Genomic trajectories of colorectal cancer with choroidal metastasis: longitudinal insights from tissue and liquid biopsy via next-generation sequencing

Identification and validation of ubiquitination-related genes for predicting cervical cancer outcome

Integrin factor (FAM27E3), as a metastatic marker of papillary thyroid carcinoma, through the p53 signaling pathway promoting lymph node metastasis

Circulating miRNAs as liquid biopsy biomarkers for diagnosis in patients with colorectal cancer: a systematic review and meta-analysis

Integrated cytomembrane proteomics identifies EpCAM/MGST1 as therapeutic targets in metastatic laryngeal carcinoma

FEZF1-AS1 drives autophagy-mediated progression of colon cancer and reduces chemosensitivity through inhabiting the PI3K/AKT/mTOR signaling pathway