Frontiers in Genetics | Cancer Genetics and Oncogenomics

Original Research

Published on 10 Mar 2025

Identification and validation of prognostic biomarkers related to tumor immune invasion in pancreatic cancer

in Cancer Genetics and Oncogenomics

Minxue Chen
Xinyuan Zhou
Yong Fan
Chen Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1556544

2,806 views

Systematic Review

Published on 06 Mar 2025

The relationship of miR-155 host gene polymorphism in the susceptibility of cancer: a systematic review and meta-analysis

in Cancer Genetics and Oncogenomics

Gang Jin
Tao Guo
Jia-Wei Liu
Han-Yu Yang
Jian-Guo Xu
Yao Pang
Yi Yang
Shao-E. He
Kang Yi

Frontiers in Genetics

doi 10.3389/fgene.2025.1517513

2,220 views

Original Research

Published on 05 Mar 2025

Study on the mechanism of KIF18B affecting the malignant progression of glioblastoma cells

in Cancer Genetics and Oncogenomics

Xiangyue Su
Liji Huang
Wei Ma
Rong Wang
Xiangjian Zeng
Gangliang Wei
Suli Mai
Min Yang
Shifu Tang

Frontiers in Genetics

doi 10.3389/fgene.2025.1540342

1,963 views
2 citations

Original Research

Published on 05 Mar 2025

Multi-omics analysis reveals Jianpi formula-derived bioactive peptide-YG-22 potentially inhibited colorectal cancer via regulating epigenetic reprogram and signal pathway regulation

in Cancer Genetics and Oncogenomics

Jun Wang
Lijuan Zhu
Yuanyuan Li
Mingming Ding
Xiyu Wang
Bo Xiong
Hongyu Chen
Lisheng Chang
Wenli Chen
Bo Han

Frontiers in Genetics

doi 10.3389/fgene.2025.1560172

2,623 views

Original Research

Published on 03 Mar 2025

Identification of biomarkers and target drugs for melanoma: a topological and deep learning approach

in Cancer Genetics and Oncogenomics

Xiwei Cui
Jipeng Song
Qingfeng Li
Jieyi Ren

Frontiers in Genetics

doi 10.3389/fgene.2025.1471037

2,795 views
2 citations

Original Research

Published on 20 Feb 2025

Deciphering the role of CNIH4 in pan-cancer landscapes and its significance in breast cancer progression

in Cancer Genetics and Oncogenomics

Yao Xu
Zengzhen Lai
Chaolin Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1536620

2,387 views

Original Research

Published on 18 Feb 2025

Identification of cancer-associated fibroblast signature genes for prognostic prediction in colorectal cancer

in Cancer Genetics and Oncogenomics

Wei Jin
Yuchang Lu
Jingen Lu
Zhenyi Wang
Yixin Yan
Biao Liang
Shiwei Qian
Jiachun Ni
Yiheng Yang
Shuo Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1476092

5,820 views
3 citations

Original Research

Published on 13 Feb 2025

Distinct gene signatures define the epithelial cell features of mucinous appendiceal neoplasms and pseudomyxoma metastases

in Cancer Genetics and Oncogenomics

Carlos Ayala
Anuja Sathe
Xiangqi Bai
Susan M. Grimes
Jeanne Shen
George A. Poultsides
Byrne Lee
Hanlee P. Ji

Frontiers in Genetics

doi 10.3389/fgene.2025.1536982

3,244 views
3 citations

Original Research

Published on 04 Feb 2025

Circular RNA microarray expression profile and potential function of circDOCK1 in colorectal cancer

in Cancer Genetics and Oncogenomics

Guojing Zhang
Xiaoyan Wu
Hongmin Fu
Daqing Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1443876

1,763 views

Original Research

Published on 03 Feb 2025

Mendelian randomization and multiomics comprehensively reveal the causal relationship and potential mechanism between atrial fibrillation and gastric cancer

in Cancer Genetics and Oncogenomics

Zhao Sicheng
Zhang Jingcheng
Zhang Shuo
Lou Jiaheng
Cai Yan
Bai Xing
Jiang Tao
Zhang Guangji

Frontiers in Genetics

doi 10.3389/fgene.2025.1446661

3,912 views

Original Research

Published on 03 Feb 2025

Integrated analysis of M2 macrophage-related gene prognostic model and single-cell sequence to predict immunotherapy response in lung adenocarcinoma

in Cancer Genetics and Oncogenomics

Meifang Li
Zhiping Wang
Bin Huang
Yanyun Lai
Meng Zhang
Cheng Lin

Frontiers in Genetics

doi 10.3389/fgene.2025.1519677

2,382 views
1 citation

Original Research

Published on 29 Jan 2025

Bibliometric analysis of ferroptosis: a comprehensive evaluation of its contribution to lung cancer

in Cancer Genetics and Oncogenomics

Feifei Yao
Feng Guo
Chuanzhong Sun
Erdong Wang
Hang Wang
Na Li

Frontiers in Genetics

doi 10.3389/fgene.2024.1449491

3,986 views
1 citation

Original Research

Published on 29 Jan 2025

GOLPH3 inhibits glioma cell apoptosis through the JNK signaling pathway

in Cancer Genetics and Oncogenomics

Shao Xie
Jiahai Ding
Zhaohao Wang
Hengliang Shi
Zheng-Quan Yu

Frontiers in Genetics

doi 10.3389/fgene.2025.1518573

1,763 views
1 citation

Original Research

Published on 24 Jan 2025

Identification of key genes underlying radiosensitivity and radioresistance in endometrial cancer through integrated bioinformatics analysis

in Cancer Genetics and Oncogenomics

Chunhui Wan
Lei Zhang
Ting Yu
Hui Lu
Han Xiao
Juan Du

Frontiers in Genetics

doi 10.3389/fgene.2025.1469610

2,355 views
2 citations

Original Research

Published on 20 Jan 2025

Therapeutic target genes and regulatory networks of gallic acid in cervical cancer

in Cancer Genetics and Oncogenomics

Zhixi You
Ye Lei
Yongkang Yang
Zhihui Zhou
Xu Chao
Keyi Ju
Songyi Wang
Yuanyuan Li

Frontiers in Genetics

doi 10.3389/fgene.2024.1508869

2,952 views
2 citations

Original Research

Published on 14 Jan 2025

Integrating single-cell RNA-seq and bulk RNA-seq to explore prognostic value and immune landscapes of methionine metabolism-related signature in breast cancer

in Cancer Genetics and Oncogenomics

Yanxian Gao
Ziyu Feng
Hailong Zhao
Xinghai Liu
Muyu Zhu
Xiafei Yu
Xiaoan Liu
Xian Wu
Jing Tao

Frontiers in Genetics

doi 10.3389/fgene.2024.1521269

4,683 views
5 citations

Original Research

Published on 10 Jan 2025

Depression-related innate immune genes and pan-cancer gene analysis and validation

in Cancer Genetics and Oncogenomics

Yakun Yang
Wei Han
Xiaoyu Zhang
Hao Yuan
Ran Wang
Jia Yang
Cuixia An
Dongyang Huang

Frontiers in Genetics

doi 10.3389/fgene.2024.1521238

3,345 views
1 citation

Original Research

Published on 09 Jan 2025

Circle-seq reveals that eccDNA may be a key blood biomarker for HBV-associated liver cancer

in Cancer Genetics and Oncogenomics

Xiao K. Ran
Xiao F. Zhao
Zhen W. Wei
Hua Z. Pang
Yan F. Tang
Rong Liu
Tie X. Wu
Xu D. Liu

Frontiers in Genetics

doi 10.3389/fgene.2024.1454153

3,556 views
1 citation

Original Research

Published on 09 Jan 2025

Single-cell RNA sequencing elucidates cellular plasticity in esophageal small cell carcinoma following chemotherapy treatment

in Cancer Genetics and Oncogenomics

Qinkai Zhang
Ziyu Gao
Ru Qiu
Jizhao Cao
Chunxiao Zhang
Wei Qin
Meiling Yang
Xinyue Wang
Ciqiu Yang
Jie Li

Frontiers in Genetics

doi 10.3389/fgene.2024.1477705

2,524 views
4 citations

Original Research

Published on 07 Jan 2025

Integrative genomic analyses combined with molecular dynamics simulations reveal the impact of deleterious mutations of Bcl-2 gene on the apoptotic machinery and implications in carcinogenesis

in Cancer Genetics and Oncogenomics

Ghazi Elamin
Zhichao Zhang
Depika Dwarka
Kabange Kasumbwe
John Mellem
Nompumelelo P. Mkhwanazi
Paradise Madlala
Mahmoud E. S. Soliman

Frontiers in Genetics

doi 10.3389/fgene.2024.1502152

2,800 views

Original Research

Published on 06 Jan 2025

Exploring the prognostic significance of lactate-mitochondria-related genes in prostate cancer

in Cancer Genetics and Oncogenomics

Yuan Wang
Ronghui Chen
Feng-Le Jiang
Xin Jiang
Yuehong Zhou
Yingying Zhou
Xinyi Hong
Chaoying Lin
Wei-Jia Wang
Sufang Qiu

Frontiers in Genetics

doi 10.3389/fgene.2024.1515045

3,090 views
1 citation

Original Research

Published on 03 Jan 2025

The value of a metabolic and immune-related gene signature and adjuvant therapeutic response in pancreatic cancer

in Cancer Genetics and Oncogenomics

Danlei Ni
Jiayi Wu
Jingjing Pan
Yajing Liang
Zihui Xu
Zhiying Yan
Kequn Xu
Feifei Wei

Frontiers in Genetics

doi 10.3389/fgene.2024.1475378

2,123 views
3 citations

Review

Published on 23 Dec 2024

Viral infection, APOBEC3 dysregulation, and cancer

in Cancer Genetics and Oncogenomics

Jake Lehle
Mohadeseh Soleimanpour
Samira Mokhtari
Diako Ebrahimi

Frontiers in Genetics

doi 10.3389/fgene.2024.1489324

3,977 views
4 citations

Review

Published on 19 Dec 2024

Dysregulation of ubiquitination modification in renal cell carcinoma

in Cancer Genetics and Oncogenomics

Hongjie You
Hui Zhang
Xiaofeng Jin
Zejun Yan

Frontiers in Genetics

doi 10.3389/fgene.2024.1453191

2,571 views
3 citations

1,180 articles

articles

Identification and validation of prognostic biomarkers related to tumor immune invasion in pancreatic cancer

The relationship of miR-155 host gene polymorphism in the susceptibility of cancer: a systematic review and meta-analysis

Study on the mechanism of KIF18B affecting the malignant progression of glioblastoma cells

Multi-omics analysis reveals Jianpi formula-derived bioactive peptide-YG-22 potentially inhibited colorectal cancer via regulating epigenetic reprogram and signal pathway regulation

Identification of biomarkers and target drugs for melanoma: a topological and deep learning approach

Deciphering the role of CNIH4 in pan-cancer landscapes and its significance in breast cancer progression

Identification of cancer-associated fibroblast signature genes for prognostic prediction in colorectal cancer

Distinct gene signatures define the epithelial cell features of mucinous appendiceal neoplasms and pseudomyxoma metastases

Circular RNA microarray expression profile and potential function of circDOCK1 in colorectal cancer

Mendelian randomization and multiomics comprehensively reveal the causal relationship and potential mechanism between atrial fibrillation and gastric cancer

Integrated analysis of M2 macrophage-related gene prognostic model and single-cell sequence to predict immunotherapy response in lung adenocarcinoma

Bibliometric analysis of ferroptosis: a comprehensive evaluation of its contribution to lung cancer

GOLPH3 inhibits glioma cell apoptosis through the JNK signaling pathway

Identification of key genes underlying radiosensitivity and radioresistance in endometrial cancer through integrated bioinformatics analysis

Therapeutic target genes and regulatory networks of gallic acid in cervical cancer

Integrating single-cell RNA-seq and bulk RNA-seq to explore prognostic value and immune landscapes of methionine metabolism-related signature in breast cancer

Depression-related innate immune genes and pan-cancer gene analysis and validation

Circle-seq reveals that eccDNA may be a key blood biomarker for HBV-associated liver cancer

Single-cell RNA sequencing elucidates cellular plasticity in esophageal small cell carcinoma following chemotherapy treatment

Integrative genomic analyses combined with molecular dynamics simulations reveal the impact of deleterious mutations of Bcl-2 gene on the apoptotic machinery and implications in carcinogenesis

Exploring the prognostic significance of lactate-mitochondria-related genes in prostate cancer

The value of a metabolic and immune-related gene signature and adjuvant therapeutic response in pancreatic cancer

Viral infection, APOBEC3 dysregulation, and cancer

Dysregulation of ubiquitination modification in renal cell carcinoma