Frontiers in Genetics | Computational Genomics

Original Research

Published on 03 Apr 2025

Role of lactylation and immune infiltration in atherosclerosis: novel insights from bioinformatics analyses

in Computational Genomics

Jintao Qian
Qing Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1520325

108 views

Original Research

Published on 01 Apr 2025

Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma

in Computational Genomics

Lichao Cao
Haoyang Dai
Shangqing Wei
Ying Ba
Fang Chen
Yingying Chen
Chendi Yu
Shenrui Zhang
Erfei Chen
Hezi Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1516232

237 views

Original Research

Accepted on 31 Mar 2025

A Novel End-to-End Learning Framework for Inferring LncRNA-Disease Associations based on Convolution Neural Network

in Computational Genomics

Shunxian Zhou
Lei Wang
Sisi Chen
Jinhai Le
Taiyang Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1580512

Original Research

Accepted on 31 Mar 2025

The potential crosstalk genes and molecular mechanisms between systemic lupus erythematosus and periodontitis

in Computational Genomics

Kai Zhao
Xiaolong Li
Qingmiao Zhu
Mengyu Zhu
Jinge Huang
ZHAO Ting

Frontiers in Genetics

doi 10.3389/fgene.2025.1527713

Technology and Code

Accepted on 31 Mar 2025

Research on the Optimization Model of Anti-Breast Cancer Candidate Drugs Based on Machine Learning

in Computational Genomics

Zhou Dong
Hong Chen
Yu chen Yang
Hai rong Hao

Frontiers in Genetics

doi 10.3389/fgene.2025.1523015

Original Research

Published on 31 Mar 2025

De novo KCNK4 variant caused epilepsy with febrile seizures plus, neurodevelopmental abnormalities, and hypertrichosis

in Computational Genomics

Hong-Jun Yan
Wen-Hui Liu
Min-Xing Xu
Peng-Yu Wang
Yu-Jie Gu
Hua Li
Jing Guo
Sheng Luo

Frontiers in Genetics

doi 10.3389/fgene.2025.1499716

198 views

Original Research

Accepted on 27 Mar 2025

Single-cell transcriptomic construction of fibroblast score for analysis of immune infiltration in primary and metastatic ovarian cancer

in Computational Genomics

Haiqiong Ye
Hongmei Ding
Qinlin Zheng

Frontiers in Genetics

doi 10.3389/fgene.2025.1549541

Technology and Code

Published on 27 Mar 2025

CirclizePlus: using ggplot2 feature to write readable R code for circular visualization

in Computational Genomics

Zheyu Zhang
Tianze Cao
Yuexia Huang
Yu Xia

Frontiers in Genetics

doi 10.3389/fgene.2025.1535368

236 views

Original Research

Accepted on 25 Mar 2025

Explore potential immune-related targets of leeches in the treatment of type 2 diabetes based on network pharmacology and machine learning

in Computational Genomics

Tairan Hu
Zhaohui Fang

Frontiers in Genetics

doi 10.3389/fgene.2025.1554622

Original Research

Published on 21 Mar 2025

A semi-supervised weighted SPCA- and convolution KAN-based model for drug response prediction

in Computational Genomics

Rui Miao
Bing-Jie Zhong
Xin-Yue Mei
Xin Dong
Yang-Dong Ou
Yong Liang
Hao-Yang Yu
Ying Wang
Zi-Han Dong

Frontiers in Genetics

doi 10.3389/fgene.2025.1532651

325 views

Original Research

Published on 21 Mar 2025

Profiling X chromosome genes expression relevant to sex dimorphism in stroke: insights from transcriptomics landscape analysis

in Computational Genomics

Xiu-De Qin
Yue-Rong Li
Qian Cai
Jia-Ye Liu
Zhao-Hui Dang
Li-Ling Li
Jia-Wei Min
Shao-Hua Qi
Fan Bu

Frontiers in Genetics

doi 10.3389/fgene.2025.1479270

390 views

Original Research

Published on 21 Mar 2025

Cancer classification in high dimensional microarray gene expressions by feature selection using eagle prey optimization

in Computational Genomics

Swetha Dhamercherla
Damodar Reddy Edla
Suresh Dara

Frontiers in Genetics

doi 10.3389/fgene.2025.1528810

305 views

Original Research

Published on 20 Mar 2025

MDNN-DTA: a multimodal deep neural network for drug-target affinity prediction

in Computational Genomics

Xu Gao
Mengfan Yan
Chengwei Zhang
Gang Wu
Jiandong Shang
Congxiang Zhang
Kecheng Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1527300

391 views

Original Research

Accepted on 19 Mar 2025

Hypergraph-Based Analysis of Weighted Gene Co-Expression Hypernetwork

in Computational Genomics

Libing Bai
Zongjin Li
Chunyang Tang
Changxin Song
Feng Hu

Frontiers in Genetics

doi 10.3389/fgene.2025.1560841

Original Research

Published on 19 Mar 2025

Identification of key genes in periodontitis

in Computational Genomics

Xianyang Cheng
Shan Shen

Frontiers in Genetics

doi 10.3389/fgene.2025.1579848

317 views

Original Research

Published on 19 Mar 2025

Mechanism of action and experimental validation of key genes common to diabetic retinopathy and coronary heart disease based on multiple bioinformatics investigations

in Computational Genomics

Fanli Jiang
Shi Yin
Xinjin Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1548147

278 views