Frontiers in Genetics | Computational Genomics

Original Research

Published on 04 Jan 2023

A microarray data analysis investigating the pathogenesis and potential biomarkers of autophagy and ferroptosis in intervertebral disc degeneration

in Computational Genomics

Wenhao Kuang
Cong Jiang
Cheng Yu
Jinwei Hu
Yang Duan
Zhong Chen

Frontiers in Genetics

doi 10.3389/fgene.2022.1090467

5,024 views
1 citation

Original Research

Published on 04 Jan 2023

A pan-cancer analysis reveals role of clusterin (CLU) in carcinogenesis and prognosis of human tumors

in Computational Genomics

Yizhe Fu
Qiao Du
Tiehan Cui
Yuying Lu
Guangliang Niu

Frontiers in Genetics

doi 10.3389/fgene.2022.1056184

4,526 views
11 citations

Original Research

Published on 04 Jan 2023

A machine learning-based approach to ERα bioactivity and drug ADMET prediction

in Computational Genomics

Tianbo An
Yueren Chen
Yefeng Chen
Leyu Ma
Jingrui Wang
Jian Zhao

Frontiers in Genetics

doi 10.3389/fgene.2022.1087273

3,028 views
8 citations

Original Research

Published on 04 Jan 2023

Breast cancer detection: Shallow convolutional neural network against deep convolutional neural networks based approach

in Computational Genomics

Himanish Shekhar Das
Akalpita Das
Anupal Neog
Saurav Mallik
Kangkana Bora
Zhongming Zhao

Frontiers in Genetics

doi 10.3389/fgene.2022.1097207

7,853 views
27 citations

Original Research

Published on 14 Dec 2022

Predicting gene expression from histone modifications with self-attention based neural networks and transfer learning

in Computational Genomics

Yuchi Chen
Minzhu Xie
Jie Wen

Frontiers in Genetics

doi 10.3389/fgene.2022.1081842

5,163 views
10 citations

Original Research

Published on 14 Dec 2022

A novel diagnostic model for predicting immune microenvironment subclass based on costimulatory molecules in lung squamous carcinoma

in Computational Genomics

Fangfang Duan
Weisen Wang
Wenyu Zhai
Junye Wang
Zerui Zhao
Lie Zheng
Bingyu Rao
Yuheng Zhou
Hao Long
Yaobin Lin

Frontiers in Genetics

doi 10.3389/fgene.2022.1078790

3,089 views

Original Research

Published on 13 Dec 2022

A hypoxia risk score for prognosis prediction and tumor microenvironment in adrenocortical carcinoma

in Computational Genomics

Yuanyuan Deng
Huihuang Li
Jinglan Fu
Ying Pu
Ying Zhang
Shijing Chen
Shiyu Tong
Huixia Liu

Frontiers in Genetics

doi 10.3389/fgene.2022.796681

3,694 views

Brief Research Report

Published on 13 Dec 2022

Substance abuse and the risk of severe COVID-19: Mendelian randomization confirms the causal role of opioids but hints a negative causal effect for cannabinoids

in Computational Genomics

M. Reza Jabalameli
Zhengdong D. Zhang

Frontiers in Genetics

doi 10.3389/fgene.2022.1070428

4,694 views
2 citations

Original Research

Published on 09 Dec 2022

Ferroptosis patterns and tumor microenvironment infiltration characterization in esophageal squamous cell cancer

in Computational Genomics

Lu-Lu Zhang
Wei-Jie Zhu
Xin-Xin Zhang
Da Feng
Xi-Cheng Wang
Ying Ding
Dong-Xia Wang
Yi-Yang Li

Frontiers in Genetics

doi 10.3389/fgene.2022.1047382

4,544 views
5 citations

Original Research

Published on 09 Dec 2022

TP53-related signature for predicting prognosis and tumor microenvironment characteristics in bladder cancer: A multi-omics study

in Computational Genomics

Yuting Tao
Xia Li
Yushan Zhang
Liangyu He
Qinchen Lu
Yaobang Wang
Lixin Pan
Zhenxing Wang
Chao Feng
Yuanliang Xie

Frontiers in Genetics

doi 10.3389/fgene.2022.1057302

5,525 views
10 citations

Original Research

Published on 09 Dec 2022

Single-cell RNA-seq data analysis using graph autoencoders and graph attention networks

in Computational Genomics

Xiang Feng
Fang Fang
Haixia Long
Rao Zeng
Yuhua Yao

Frontiers in Genetics

doi 10.3389/fgene.2022.1003711

4,862 views
4 citations

Original Research

Published on 09 Dec 2022

Comprehensive analysis of immune-related gene signature based on ssGSEA algorithms in the prognosis and immune landscape of hepatocellular carcinoma

in Computational Genomics

Liangliang Wang
Li Wang
Peihong He

Frontiers in Genetics

doi 10.3389/fgene.2022.1064432

4,053 views
7 citations

Original Research

Published on 08 Dec 2022

ggMOB: Elucidation of genomic conjugative features and associated cargo genes across bacterial genera using genus-genus mobilization networks

in Computational Genomics

Gowri Nayar
Ignacio Terrizzano
Ed Seabolt
Akshay Agarwal
Christina Boucher
Jaime Ruiz
Ilya B. Slizovskiy
James H. Kaufman
Noelle R. Noyes

Frontiers in Genetics

doi 10.3389/fgene.2022.1024577

2,076 views
3 citations

Original Research

Published on 08 Dec 2022

Integrated single-cell and bulk RNA sequencing analyses reveal a prognostic signature of cancer-associated fibroblasts in head and neck squamous cell carcinoma

in Computational Genomics

Yichen Yang
Ben Ma
Litao Han
Weibo Xu
Xiaoxue Du
Wenjun Wei
Tian Liao
Qinghai Ji
Ning Qu
Yu Wang

Frontiers in Genetics

doi 10.3389/fgene.2022.1028469

6,045 views
9 citations

Original Research

Published on 06 Dec 2022

Kalpra: A kernel approach for longitudinal pathway regression analysis integrating network information with an application to the longitudinal PsyCourse Study

in Computational Genomics

Bernadette Wendel
Markus Heidenreich
Monika Budde
Maria Heilbronner
Mojtaba Oraki Kohshour
Sergi Papiol
Peter Falkai
Thomas G. Schulze
Urs Heilbronner
Heike Bickeböller

Frontiers in Genetics

doi 10.3389/fgene.2022.1015885

1,718 views

Original Research

Published on 06 Dec 2022

Evaluation of liver function in patients with liver cirrhosis and chronic liver disease using functional liver imaging scores at different acquisition time points

in Computational Genomics

Guixiang Tang
Jianbin Liu
Peng Liu
Feng Huang
Xunuo Shao
Yao Chen
An Xie

Frontiers in Genetics

doi 10.3389/fgene.2022.1071025

2,764 views
2 citations