Frontiers in Genetics | Computational Genomics

Original Research

Published on 06 Dec 2022

A Wnt-related gene expression signature to improve the prediction of prognosis and tumor microenvironment in gastric cancer

in Computational Genomics

Shuai Kong
Zhi Li
Yuanyuan Wang
Zheming Zhang
Xianghao Jia
Xinxin Gao
Bicong Cong
Fangxu Zhang
Jing Zhang
Chunning Zheng

Frontiers in Genetics

doi 10.3389/fgene.2022.1035099

2,293 views
1 citation

Original Research

Published on 06 Dec 2022

Identification of key genes in late-onset major depressive disorder through a co-expression network module

in Computational Genomics

Ping-An Yao
Hai-Ju Sun
Xiao-Yu Li

Frontiers in Genetics

doi 10.3389/fgene.2022.1048761

2,730 views
7 citations

Original Research

Published on 05 Dec 2022

Integrative analyses of a mitophagy-related gene signature for predicting prognosis in patients with uveal melanoma

in Computational Genomics

Yanhua Cheng
Jingying Liu
Huimin Fan
Kangcheng Liu
Hua Zou
Zhipeng You

Frontiers in Genetics

doi 10.3389/fgene.2022.1050341

3,611 views
4 citations

Original Research

Published on 02 Dec 2022

Bioinformatics analysis of genes related to ferroptosis in hepatic ischemia-reperfusion injury

in Computational Genomics

Shuo Sun
Jianming Xue
Yunfei Guo
Jianling Li

Frontiers in Genetics

doi 10.3389/fgene.2022.1072544

4,125 views
5 citations

Original Research

Published on 02 Dec 2022

Prediction of potential small molecule−miRNA associations based on heterogeneous network representation learning

in Computational Genomics

Jianwei Li
Hongxin Lin
Yinfei Wang
Zhiguang Li
Baoqin Wu

Frontiers in Genetics

doi 10.3389/fgene.2022.1079053

2,806 views
8 citations

Original Research

Published on 01 Dec 2022

TYK2 correlates with immune infiltration: A prognostic marker for head and neck squamous cell carcinoma

in Computational Genomics

Yaodong He
Yunshan Li
Junwei Xiang
Xu Huang
Mingyu Zhao
Yuanyin Wang
Ran Chen

Frontiers in Genetics

doi 10.3389/fgene.2022.1081519

4,321 views
2 citations

Original Research

Published on 01 Dec 2022

A novel approach for a joint analysis of isomiR and mRNA expression data reveals features of isomiR targeting in breast cancer

in Computational Genomics

Stepan Nersisyan
Anton Zhiyanov
Narek Engibaryan
Diana Maltseva
Alexander Tonevitsky

Frontiers in Genetics

doi 10.3389/fgene.2022.1070528

3,131 views
6 citations

Original Research

Published on 01 Dec 2022

LFSC: A linear fast semi-supervised clustering algorithm that integrates reference-bulk and single-cell transcriptomes

in Computational Genomics

Qiaoming Liu
Yingjian Liang
Dong Wang
Jie Li

Frontiers in Genetics

doi 10.3389/fgene.2022.1068075

3,467 views
2 citations

Original Research

Published on 01 Dec 2022

Integrated investigation of the prognostic role of HLA LOH in advanced lung cancer patients with immunotherapy

in Computational Genomics

Xiaotao Zhang
Hongzhen Tang
Haitao Luo
Huiping Lu
Chaohu Pan
Haiming Yu
Linlin Zhang
Yaping Guan
Lan Yu
Huili Chu

Frontiers in Genetics

doi 10.3389/fgene.2022.1066636

5,560 views
10 citations

Systematic Review

Published on 01 Dec 2022

Synthetic lethal gene pairs: Experimental approaches and predictive models

in Computational Genomics

Shan Tang
Birkan Gökbağ
Kunjie Fan
Shuai Shao
Yang Huo
Xue Wu
Lijun Cheng
Lang Li

Frontiers in Genetics

doi 10.3389/fgene.2022.961611

10,378 views
17 citations

Original Research

Published on 30 Nov 2022

Data-driven analysis to identify prognostic immune-related biomarkers in BRAF mutated cutaneous melanoma microenvironment

in Computational Genomics

Biao Huang
Wenxing Su
Daojiang Yu

Frontiers in Genetics

doi 10.3389/fgene.2022.1081418

1,771 views
1 citation

Original Research

Published on 30 Nov 2022

piRNAs may regulate expression of candidate genes of esophageal adenocarcinoma

in Computational Genomics

A. N. Akimniyazova
T. K. Niyazova
O. Yu. Yurikova
A. Yu. Pyrkova
M. A. Zhanuzakov
A. T. Ivashchenko

Frontiers in Genetics

doi 10.3389/fgene.2022.1069637

2,270 views
4 citations

Original Research

Published on 29 Nov 2022

TSSNote-CyaPromBERT: Development of an integrated platform for highly accurate promoter prediction and visualization of Synechococcus sp. and Synechocystis sp. through a state-of-the-art natural language processing model BERT

in Computational Genomics

Dung Hoang Anh Mai
Linh Thanh Nguyen
Eun Yeol Lee

Frontiers in Genetics

doi 10.3389/fgene.2022.1067562

3,890 views
15 citations

Original Research

Published on 29 Nov 2022

Development and performance evaluation of an artificial intelligence algorithm using cell-free DNA fragment distance for non-invasive prenatal testing (aiD-NIPT)

in Computational Genomics

Junnam Lee
Sae-Mi Lee
Jin Mo Ahn
Tae-Rim Lee
Wan Kim
Eun-Hae Cho
Chang-Seok Ki

Frontiers in Genetics

doi 10.3389/fgene.2022.999587

6,231 views
7 citations

Review

Published on 29 Nov 2022

Insights on variant analysis in silico tools for pathogenicity prediction

in Computational Genomics

Felipe Antonio de Oliveira Garcia
Edilene Santos de Andrade
Edenir Inez Palmero

Frontiers in Genetics

doi 10.3389/fgene.2022.1010327

23,916 views
64 citations

Original Research

Published on 28 Nov 2022

A signal recognition particle-related joint model of LASSO regression, SVM-RFE and artificial neural network for the diagnosis of systemic sclerosis-associated pulmonary hypertension

in Computational Genomics

Jingxi Xu
Chaoyang Liang
Jiangtao Li

Frontiers in Genetics

doi 10.3389/fgene.2022.1078200

8,359 views
9 citations