Frontiers in Genetics | Computational Genomics

Original Research

Published on 18 Nov 2021

Identification of a Six-Gene Prognostic Signature Characterized by Tumor Microenvironment Immune Profiles in Clear Cell Renal Cell Carcinoma

in Computational Genomics

Lu Zhang
Jianlong Li
Mengzhao Zhang
Lu Wang
Tao Yang
Qiuya Shao
Xiao Liang
Minghai Ma
Nan Zhang
Minxuan Jing

Frontiers in Genetics

doi 10.3389/fgene.2021.722421

3,249 views
5 citations

Brief Research Report

Published on 18 Nov 2021

Evaluation of Germline Structural Variant Calling Methods for Nanopore Sequencing Data

in Computational Genomics

Davide Bolognini
Alberto Magi

Frontiers in Genetics

doi 10.3389/fgene.2021.761791

11,664 views
21 citations

Original Research

Published on 17 Nov 2021

CD73 Severed as a Potential Prognostic Marker and Promote Lung Cancer Cells Migration via Enhancing EMT Progression

in Computational Genomics

Zhao-wei Gao
Chong Liu
Lan Yang
Hao-chuan Chen
Long-fei Yang
Hui-zhong Zhang
Ke Dong

Frontiers in Genetics

doi 10.3389/fgene.2021.728200

5,105 views
28 citations

Original Research

Published on 16 Nov 2021

Combination of Tumor Mutational Burden and Specific Gene Mutations Stratifies Outcome to Immunotherapy Across Recurrent and Metastatic Head and Neck Squamous Cell Carcinoma

in Computational Genomics

Ying-Peng Peng
Rong Wang
Qiao-Dan Liu
Xi-Wei Xu
Wei Wei
Xiao-Tao Huang
Xiao-Mou Peng
Zhi-Gang Liu

Frontiers in Genetics

doi 10.3389/fgene.2021.756506

6,956 views
9 citations

Original Research

Published on 16 Nov 2021

Weighted Gene Co-Expression Network Analysis and Treatment Strategies of Tumor Recurrence-Associated Hub Genes in Lung Adenocarcinoma

in Computational Genomics

Zhengze Shen
Shengwei Liu
Jie Liu
Jingdong Liu
Caoyuan Yao

Frontiers in Genetics

doi 10.3389/fgene.2021.756235

4,807 views
12 citations

Original Research

Published on 16 Nov 2021

Identification of Six Prognostic Genes in EGFR–Mutant Lung Adenocarcinoma Using Structure Network Algorithms

in Computational Genomics

Haomin Zhang
Di Lu
Qinglun Li
Fengfeng Lu
Jundong Zhang
Zining Wang
Xuechun Lu
Jinliang Wang

Frontiers in Genetics

doi 10.3389/fgene.2021.755245

5,722 views
5 citations

Original Research

Published on 15 Nov 2021

Identification of Immune-Related Key Genes in Ovarian Cancer Based on WGCNA

in Computational Genomics

Qingli Quan
Xinxin Xiong
Shanyun Wu
Meixing Yu

Frontiers in Genetics

doi 10.3389/fgene.2021.760225

16,329 views
39 citations

Original Research

Published on 15 Nov 2021

Comprehensive Analysis of the Tumor Microenvironment and Ferroptosis-Related Genes Predict Prognosis with Ovarian Cancer

in Computational Genomics

Xiao-xue Li
Li Xiong
Yu Wen
Zi-jian Zhang

Frontiers in Genetics

doi 10.3389/fgene.2021.774400

4,791 views
13 citations

Original Research

Published on 12 Nov 2021

Identification of Genetic Predisposition in Noncirrhotic Portal Hypertension Patients With Multiple Renal Cysts by Integrated Analysis of Whole-Genome and Single-Cell RNA Sequencing

in Computational Genomics

Yanjing Wu
Yongle Wu
Kun Liu
Hui Liu
Shanshan Wang
Jian Huang
Huiguo Ding

Frontiers in Genetics

doi 10.3389/fgene.2021.775470

4,536 views
2 citations

Original Research

Published on 12 Nov 2021

Improving the Classification of Alzheimer’s Disease Using Hybrid Gene Selection Pipeline and Deep Learning

in Computational Genomics

Nivedhitha Mahendran
P. M. Durai Raj Vincent
Kathiravan Srinivasan
Chuan-Yu Chang

Frontiers in Genetics

doi 10.3389/fgene.2021.784814

5,892 views
37 citations

Original Research

Published on 12 Nov 2021

Research on Mental Stress Recognition of Depressive Disorders in Patients With Androgenic Alopecia Based on Machine Learning and Fuzzy K-Means Clustering

in Computational Genomics

Yulong Li
Baojin Wu
Xiujun Li
Qin Zhou
Xin Yang
Yufei Li

Frontiers in Genetics

doi 10.3389/fgene.2021.751791

3,839 views
9 citations

Original Research

Published on 11 Nov 2021

Evolutionary and Antigenic Profiling of the Tendentious D614G Mutation of SARS-CoV-2 in Gujarat, India

in Computational Genomics

Jay Nimavat
Chandrashekar Mootapally
Neelam M. Nathani
Devyani Dave
Mukesh N. Kher
Mayur S. Mahajan
Chaitanya G. Joshi
Vaibhav D. Bhatt

Frontiers in Genetics

doi 10.3389/fgene.2021.764927

3,201 views

Original Research

Published on 11 Nov 2021

Leptin Receptor Overlapping Transcript (LEPROT) Is Associated with the Tumor Microenvironment and a Prognostic Predictor in Pan-Cancer

in Computational Genomics

Bingsheng Li
Yao He
Pan Li
Xiang Chen

Frontiers in Genetics

doi 10.3389/fgene.2021.749435

6,526 views
7 citations

Original Research

Published on 11 Nov 2021

Identification of Intercellular Signaling Changes Across Conditions and Their Influence on Intracellular Signaling Response From Multiple Single-Cell Datasets

in Computational Genomics

Mengqian Hao
Xiufen Zou
Suoqin Jin

Frontiers in Genetics

doi 10.3389/fgene.2021.751158

15,147 views
15 citations

Original Research

Published on 11 Nov 2021

A Novel Mutation of the KLK6 Gene in a Family With Knee Osteoarthritis

in Computational Genomics

Yanzhi Ge
Chenfen Zhou
Xiujuan Xiao
Zhijiang Jin
Li Zhou
Zuxiang Chen
Fucun Liu
Qiang Yuan
Guoqing Zhang
Letian Shan

Frontiers in Genetics

doi 10.3389/fgene.2021.784176

3,791 views
7 citations

Editorial

Published on 11 Nov 2021

Editorial: Unsupervised Learning Models for Unlabeled Genomic, Transcriptomic & Proteomic Data

in Computational Genomics

Jianing Xi
Zhenhua Yu

Frontiers in Genetics

doi 10.3389/fgene.2021.781698

2,645 views
4 citations

Original Research

Published on 11 Nov 2021

PPP1R14B Is a Prognostic and Immunological Biomarker in Pan-Cancer

in Computational Genomics

Mingxia Deng
Long Peng
Jiamin Li
Xiong Liu
Xichun Xia
Guangqiang Li

Frontiers in Genetics

doi 10.3389/fgene.2021.763561

10,476 views
27 citations

Original Research

Published on 11 Nov 2021

Inferring Differential Networks by Integrating Gene Expression Data With Additional Knowledge

in Computational Genomics

Chen Liu
Dehan Cai
WuCha Zeng
Yun Huang

Frontiers in Genetics

doi 10.3389/fgene.2021.760155

3,232 views

Original Research

Published on 11 Nov 2021

LBX2-AS1 Activates FSTL3 by Binding to Transcription Factor RARα to Foster Proliferation, Migration, and Invasion of Thyroid Cancer

in Computational Genomics

Jia Li
Jie Shen
Lan Qin
Dongyan Lu
Enci Ding

Frontiers in Genetics

doi 10.3389/fgene.2021.765033

3,475 views
10 citations

Original Research

Published on 11 Nov 2021

Calculation of Similarity Between 26 Autoimmune Diseases Based on Three Measurements Including Network, Function, and Semantics

in Computational Genomics

Yanjun Ding
Mintian Cui
Jun Qian
Chao Wang
Qi Shen
Hongbiao Ren
Liangshuang Li
Fengmin Zhang
Ruijie Zhang

Frontiers in Genetics

doi 10.3389/fgene.2021.758041

4,105 views
3 citations

Original Research

Published on 10 Nov 2021

Predicting Bone Metastasis Using Gene Expression-Based Machine Learning Models

in Computational Genomics

Somayah Albaradei
Mahmut Uludag
Maha A. Thafar
Takashi Gojobori
Magbubah Essack
Xin Gao

Frontiers in Genetics

doi 10.3389/fgene.2021.771092

6,663 views
18 citations

Brief Research Report

Published on 09 Nov 2021

Genomic Analysis of Multidrug-Resistant Mycobacterium tuberculosis Strains From Patients in Kazakhstan

in Computational Genomics

Asset Daniyarov
Askhat Molkenov
Saule Rakhimova
Ainur Akhmetova
Dauren Yerezhepov
Lyailya Chingissova
Venera Bismilda
Bekzat Toksanbayeva
Anar Rakisheva
Ainur Akilzhanova

Frontiers in Genetics

doi 10.3389/fgene.2021.683515

7,808 views
12 citations

Editorial

Published on 08 Nov 2021

Editorial: Bioinformatics of Genome Regulation, Volume II

in Computational Genomics

Yuriy L. Orlov
Anastasia A. Anashkina
Tatiana V. Tatarinova
Ancha V. Baranova

Frontiers in Genetics

doi 10.3389/fgene.2021.795257

2,442 views
7 citations

Original Research

Published on 08 Nov 2021

Hybrid Clustering of Single-Cell Gene Expression and Spatial Information via Integrated NMF and K-Means

in Computational Genomics

Sooyoun Oh
Haesun Park
Xiuwei Zhang

Frontiers in Genetics

doi 10.3389/fgene.2021.763263

5,075 views
7 citations

2,653 articles

articles

Identification of a Six-Gene Prognostic Signature Characterized by Tumor Microenvironment Immune Profiles in Clear Cell Renal Cell Carcinoma

Evaluation of Germline Structural Variant Calling Methods for Nanopore Sequencing Data

CD73 Severed as a Potential Prognostic Marker and Promote Lung Cancer Cells Migration via Enhancing EMT Progression

Combination of Tumor Mutational Burden and Specific Gene Mutations Stratifies Outcome to Immunotherapy Across Recurrent and Metastatic Head and Neck Squamous Cell Carcinoma

Weighted Gene Co-Expression Network Analysis and Treatment Strategies of Tumor Recurrence-Associated Hub Genes in Lung Adenocarcinoma

Identification of Six Prognostic Genes in EGFR–Mutant Lung Adenocarcinoma Using Structure Network Algorithms

Identification of Immune-Related Key Genes in Ovarian Cancer Based on WGCNA

Comprehensive Analysis of the Tumor Microenvironment and Ferroptosis-Related Genes Predict Prognosis with Ovarian Cancer

Identification of Genetic Predisposition in Noncirrhotic Portal Hypertension Patients With Multiple Renal Cysts by Integrated Analysis of Whole-Genome and Single-Cell RNA Sequencing

Improving the Classification of Alzheimer’s Disease Using Hybrid Gene Selection Pipeline and Deep Learning

Research on Mental Stress Recognition of Depressive Disorders in Patients With Androgenic Alopecia Based on Machine Learning and Fuzzy K-Means Clustering

Evolutionary and Antigenic Profiling of the Tendentious D614G Mutation of SARS-CoV-2 in Gujarat, India

Leptin Receptor Overlapping Transcript (LEPROT) Is Associated with the Tumor Microenvironment and a Prognostic Predictor in Pan-Cancer

Identification of Intercellular Signaling Changes Across Conditions and Their Influence on Intracellular Signaling Response From Multiple Single-Cell Datasets

A Novel Mutation of the KLK6 Gene in a Family With Knee Osteoarthritis

Editorial: Unsupervised Learning Models for Unlabeled Genomic, Transcriptomic & Proteomic Data

PPP1R14B Is a Prognostic and Immunological Biomarker in Pan-Cancer

Inferring Differential Networks by Integrating Gene Expression Data With Additional Knowledge

LBX2-AS1 Activates FSTL3 by Binding to Transcription Factor RARα to Foster Proliferation, Migration, and Invasion of Thyroid Cancer

Calculation of Similarity Between 26 Autoimmune Diseases Based on Three Measurements Including Network, Function, and Semantics

Predicting Bone Metastasis Using Gene Expression-Based Machine Learning Models

Genomic Analysis of Multidrug-Resistant Mycobacterium tuberculosis Strains From Patients in Kazakhstan

Editorial: Bioinformatics of Genome Regulation, Volume II

Hybrid Clustering of Single-Cell Gene Expression and Spatial Information via Integrated NMF and K-Means