Frontiers in Genetics | Computational Genomics

Original Research

Published on 23 Jun 2021

Identifying the Key Genes in Mouse Liver Regeneration After Partial Hepatectomy by Bioinformatics Analysis and in vitro/vivo Experiments

in Computational Genomics

Jian Zhao
Shi-Zhe Yu
Qiang Cai
Duo Ma
Long Jiang
Ling-Peng Yang
Zhi-Yong Yu

Frontiers in Genetics

doi 10.3389/fgene.2021.670706

6,678 views
6 citations

Methods

Published on 23 Jun 2021

Overlapping Structures Detection in Protein-Protein Interaction Networks Using Community Detection Algorithm Based on Neighbor Clustering Coefficient

in Computational Genomics

Yan Wang
Qiong Chen
Lili Yang
Sen Yang
Kai He
Xuping Xie

Frontiers in Genetics

doi 10.3389/fgene.2021.689515

5,166 views
7 citations

Original Research

Published on 23 Jun 2021

Integrated Analysis of Microarray and RNA-Seq Data for the Identification of Hub Genes and Networks Involved in the Pancreatic Cancer

in Computational Genomics

Maryum Nisar
Rehan Zafar Paracha
Iqra Arshad
Sidra Adil
Sabaoon Zeb
Rumeza Hanif
Mehak Rafiq
Zamir Hussain

Frontiers in Genetics

doi 10.3389/fgene.2021.663787

15,637 views
22 citations

Original Research

Published on 23 Jun 2021

A Peptide Vaccine Candidate Tailored to Individuals' Genetics Mimics the Multi-Targeted T Cell Immunity of COVID-19 Convalescent Subjects

in Computational Genomics

Eszter Somogyi
Zsolt Csiszovszki
Levente Molnár
Orsolya Lőrincz
József Tóth
Sofie Pattijn
Jana Schockaert
Aurélie Mazy
István Miklós
Katalin Pántya

Frontiers in Genetics

doi 10.3389/fgene.2021.684152

15,125 views
15 citations

Original Research

Published on 22 Jun 2021

Disruptive Selection of Human Immunostimulatory and Immunosuppressive Genes Both Provokes and Prevents Rheumatoid Arthritis, Respectively, as a Self-Domestication Syndrome

in Computational Genomics

Natalya V. Klimova
Evgeniya Oshchepkova
Irina Chadaeva
Ekaterina Sharypova
Petr Ponomarenko
Irina Drachkova
Dmitry Rasskazov
Dmitry Oshchepkov
Mikhail Ponomarenko
Ludmila Savinkova

Frontiers in Genetics

doi 10.3389/fgene.2021.610774

4,893 views
5 citations

Review

Published on 21 Jun 2021

Application of Machine Learning for Drug–Target Interaction Prediction

in Computational Genomics

Lei Xu
Xiaoqing Ru
Rong Song

Frontiers in Genetics

doi 10.3389/fgene.2021.680117

22,069 views
64 citations

Original Research

Published on 18 Jun 2021

Genotyping and Whole-Genome Resequencing of Welsh Sheep Breeds Reveal Candidate Genes and Variants for Adaptation to Local Environment and Socioeconomic Traits

in Computational Genomics

James Sweet-Jones
Vasileios Panagiotis Lenis
Andrey A. Yurchenko
Nikolay S. Yudin
Martin Swain
Denis M. Larkin

Frontiers in Genetics

doi 10.3389/fgene.2021.612492

7,315 views
17 citations

Original Research

Published on 18 Jun 2021

A Novel Immune-Related Prognostic Signature in Head and Neck Squamous Cell Carcinoma

in Computational Genomics

Yi Zhang
Ping Chen
Qiang Zhou
Hongyan Wang
Qingquan Hua
Jie Wang
Hongliang Zhong

Frontiers in Genetics

doi 10.3389/fgene.2021.570336

6,188 views
17 citations

Case Report

Published on 17 Jun 2021

Case Report: Review of CT Findings and Histopathological Characteristics of Primary Liver Carcinosarcoma

in Computational Genomics

Lu Huang
Lijian Lu

Frontiers in Genetics

doi 10.3389/fgene.2021.638636

7,780 views
3 citations

Data Report

Published on 17 Jun 2021

Nanopore and Illumina Genome Sequencing of Fusarium oxysporum f. sp. lini Strains of Different Virulence

in Computational Genomics

Ekaterina M. Dvorianinova
Elena N. Pushkova
Roman O. Novakovskiy
Liubov V. Povkhova
Nadezhda L. Bolsheva
Ludmila P. Kudryavtseva
Tatiana A. Rozhmina
Nataliya V. Melnikova
Alexey A. Dmitriev

Frontiers in Genetics

doi 10.3389/fgene.2021.662928

6,794 views
14 citations

Original Research

Published on 16 Jun 2021

Prognostic Value of MEG3 and Its Correlation With Immune Infiltrates in Gliomas

in Computational Genomics

Xiaoping Xu
Zhenglan Zhong
Yongxiang Shao
Yong Yi

Frontiers in Genetics

doi 10.3389/fgene.2021.679097

4,856 views
17 citations

Original Research

Published on 15 Jun 2021

IGFBP2 Is a Potential Master Regulator Driving the Dysregulated Gene Network Responsible for Short Survival in Glioblastoma Multiforme

in Computational Genomics

Manasa Kalya
Alexander Kel
Darius Wlochowitz
Edgar Wingender
Tim Beißbarth

Frontiers in Genetics

doi 10.3389/fgene.2021.670240

7,344 views
12 citations

Original Research

Published on 15 Jun 2021

Associations Between Sleep Quality and Health Span: A Prospective Cohort Study Based on 328,850 UK Biobank Participants

in Computational Genomics

Muhammed Lamin Sambou
Xiaoyu Zhao
Tongtong Hong
Jingyi Fan
Til Bahadur Basnet
Meng Zhu
Cheng Wang
Dong Hang
Yue Jiang
Juncheng Dai

Frontiers in Genetics

doi 10.3389/fgene.2021.663449

16,043 views
28 citations

Original Research

Published on 15 Jun 2021

Revisiting an Expression Dataset of Discordant Inflammatory Bowel Disease Twin Pairs Using a Mutation Burden Test Reveals CYP2C18 as a Novel Marker

in Computational Genomics

Juan Du
Jie Yin
Haojie Du
Jiawei Zhang

Frontiers in Genetics

doi 10.3389/fgene.2021.680125

4,399 views
10 citations

Original Research

Published on 15 Jun 2021

Characterizing Promoter and Enhancer Sequences by a Deep Learning Method

in Computational Genomics

Xin Zeng
Sung-Joon Park
Kenta Nakai

Frontiers in Genetics

doi 10.3389/fgene.2021.681259

16,447 views
5 citations

Original Research

Published on 14 Jun 2021

A Machine Learning Method to Identify Genetic Variants Potentially Associated With Alzheimer’s Disease

in Computational Genomics

Bradley Monk
Andrei Rajkovic
Semar Petrus
Aleks Rajkovic
Terry Gaasterland
Roberto Malinow

Frontiers in Genetics

doi 10.3389/fgene.2021.647436

7,595 views
15 citations

Original Research

Published on 14 Jun 2021

Identifying Hypoxia Characteristics to Stratify Prognosis and Assess the Tumor Immune Microenvironment in Renal Cell Carcinoma

in Computational Genomics

Zhenan Zhang
Qinhan Li
Feng Wang
Binglei Ma
Yisen Meng
Qian Zhang

Frontiers in Genetics

doi 10.3389/fgene.2021.606816

4,411 views
16 citations

Original Research

Published on 14 Jun 2021

Predicting the Risk Genes of Autism Spectrum Disorders

in Computational Genomics

Yenching Lin
Srinivasulu Yerukala Sathipati
Shinn-Ying Ho

Frontiers in Genetics

doi 10.3389/fgene.2021.665469

7,759 views
15 citations

Perspective

Published on 14 Jun 2021

Challenges, Strategies, and Perspectives for Reference-Independent Longitudinal Multi-Omic Microbiome Studies

in Computational Genomics

Susana Martínez Arbas
Susheel Bhanu Busi
Pedro Queirós
Laura de Nies
Malte Herold
Patrick May
Paul Wilmes
Emilie E. L. Muller
Shaman Narayanasamy

Frontiers in Genetics

doi 10.3389/fgene.2021.666244

8,847 views
17 citations

Original Research

Published on 14 Jun 2021

Genome of the Single Human Chromosome 18 as a “Gold Standard” for Its Transcriptome

in Computational Genomics

Ekaterina Ilgisonis
Nikita Vavilov
Elena Ponomarenko
Andrey Lisitsa
Ekaterina Poverennaya
Victor Zgoda
Sergey Radko
Alexander Archakov

Frontiers in Genetics

doi 10.3389/fgene.2021.674534

3,950 views
9 citations

Original Research

Published on 11 Jun 2021

Identification of the Signature Associated With m6A RNA Methylation Regulators and m6A-Related Genes and Construction of the Risk Score for Prognostication in Early-Stage Lung Adenocarcinoma

in Computational Genomics

Bingzhou Guo
Hongliang Zhang
Jinliang Wang
Rilige Wu
Junyan Zhang
Qiqin Zhang
Lu Xu
Ming Shen
Zhibo Zhang
Fangyan Gu

Frontiers in Genetics

doi 10.3389/fgene.2021.656114

5,263 views
14 citations

Original Research

Published on 09 Jun 2021

Whole Transcriptome Data Analysis Reveals Prognostic Signature Genes for Overall Survival Prediction in Diffuse Large B Cell Lymphoma

in Computational Genomics

Mengmeng Pan
Pingping Yang
Fangce Wang
Xiu Luo
Bing Li
Yi Ding
Huina Lu
Yan Dong
Wenjun Zhang
Bing Xiu

Frontiers in Genetics

doi 10.3389/fgene.2021.648800

4,616 views
6 citations

Original Research

Published on 07 Jun 2021

Automated Facial Recognition for Noonan Syndrome Using Novel Deep Convolutional Neural Network With Additive Angular Margin Loss

in Computational Genomics

Hang Yang
Xin-Rong Hu
Ling Sun
Dian Hong
Ying-Yi Zheng
Ying Xin
Hui Liu
Min-Yin Lin
Long Wen
Dong-Po Liang

Frontiers in Genetics

doi 10.3389/fgene.2021.669841

7,822 views
16 citations

Original Research

Published on 07 Jun 2021

Identifying Key Somatic Copy Number Alterations Driving Dysregulation of Cancer Hallmarks in Lower-Grade Glioma

in Computational Genomics

Yao Zhou
Shuai Wang
Haoteng Yan
Bo Pang
Xinxin Zhang
Lin Pang
Yihan Wang
Jinyuan Xu
Jing Hu
Yujia Lan

Frontiers in Genetics

doi 10.3389/fgene.2021.654736

4,903 views
10 citations

2,653 articles

articles

Identifying the Key Genes in Mouse Liver Regeneration After Partial Hepatectomy by Bioinformatics Analysis and in vitro/vivo Experiments

Overlapping Structures Detection in Protein-Protein Interaction Networks Using Community Detection Algorithm Based on Neighbor Clustering Coefficient

Integrated Analysis of Microarray and RNA-Seq Data for the Identification of Hub Genes and Networks Involved in the Pancreatic Cancer

A Peptide Vaccine Candidate Tailored to Individuals' Genetics Mimics the Multi-Targeted T Cell Immunity of COVID-19 Convalescent Subjects

Disruptive Selection of Human Immunostimulatory and Immunosuppressive Genes Both Provokes and Prevents Rheumatoid Arthritis, Respectively, as a Self-Domestication Syndrome

Application of Machine Learning for Drug–Target Interaction Prediction

Genotyping and Whole-Genome Resequencing of Welsh Sheep Breeds Reveal Candidate Genes and Variants for Adaptation to Local Environment and Socioeconomic Traits

A Novel Immune-Related Prognostic Signature in Head and Neck Squamous Cell Carcinoma

Case Report: Review of CT Findings and Histopathological Characteristics of Primary Liver Carcinosarcoma

Nanopore and Illumina Genome Sequencing of Fusarium oxysporum f. sp. lini Strains of Different Virulence

Prognostic Value of MEG3 and Its Correlation With Immune Infiltrates in Gliomas

IGFBP2 Is a Potential Master Regulator Driving the Dysregulated Gene Network Responsible for Short Survival in Glioblastoma Multiforme

Associations Between Sleep Quality and Health Span: A Prospective Cohort Study Based on 328,850 UK Biobank Participants

Revisiting an Expression Dataset of Discordant Inflammatory Bowel Disease Twin Pairs Using a Mutation Burden Test Reveals CYP2C18 as a Novel Marker

Characterizing Promoter and Enhancer Sequences by a Deep Learning Method

A Machine Learning Method to Identify Genetic Variants Potentially Associated With Alzheimer’s Disease

Identifying Hypoxia Characteristics to Stratify Prognosis and Assess the Tumor Immune Microenvironment in Renal Cell Carcinoma

Predicting the Risk Genes of Autism Spectrum Disorders

Challenges, Strategies, and Perspectives for Reference-Independent Longitudinal Multi-Omic Microbiome Studies

Genome of the Single Human Chromosome 18 as a “Gold Standard” for Its Transcriptome

Identification of the Signature Associated With m6A RNA Methylation Regulators and m6A-Related Genes and Construction of the Risk Score for Prognostication in Early-Stage Lung Adenocarcinoma

Whole Transcriptome Data Analysis Reveals Prognostic Signature Genes for Overall Survival Prediction in Diffuse Large B Cell Lymphoma

Automated Facial Recognition for Noonan Syndrome Using Novel Deep Convolutional Neural Network With Additive Angular Margin Loss

Identifying Key Somatic Copy Number Alterations Driving Dysregulation of Cancer Hallmarks in Lower-Grade Glioma