Frontiers in Genetics | Genomic Assay Technology

Original Research

Published on 29 Jul 2021

Role of the kdpDE Regulatory Operon of Mycobacterium tuberculosis in Modulating Bacterial Growth in vitro

in Genomic Assay Technology

Moloko C. Cholo
Maborwa T. Matjokotja
Ayman G. Osman
Ronald Anderson

Frontiers in Genetics

doi 10.3389/fgene.2021.698875

3,669 views
11 citations

Methods

Published on 27 Jul 2021

mRBioM: An Algorithm for the Identification of Potential mRNA Biomarkers From Complete Transcriptomic Profiles of Gastric Adenocarcinoma

in Genomic Assay Technology

Changlong Dong
Nini Rao
Wenju Du
Fenglin Gao
Xiaoqin Lv
Guangbin Wang
Junpeng Zhang

Frontiers in Genetics

doi 10.3389/fgene.2021.679612

3,075 views
4 citations

Original Research

Published on 21 Jul 2021

The Optimal Cutoff Value of Z-scores Enhances the Judgment Accuracy of Noninvasive Prenatal Screening

in Genomic Assay Technology

Lingna Zhou
Bin Zhang
Jianbing Liu
Ye Shi
Jing Wang
Bin Yu

Frontiers in Genetics

doi 10.3389/fgene.2021.690063

14,208 views
16 citations

Original Research

Published on 16 Jul 2021

Comprehensive Evaluation of Non-invasive Prenatal Screening to Detect Fetal Copy Number Variations

in Genomic Assay Technology

Jing Wang
Bin Zhang
Lingna Zhou
Qin Zhou
Yingping Chen
Bin Yu

Frontiers in Genetics

doi 10.3389/fgene.2021.665589

3,631 views
6 citations

Brief Research Report

Published on 18 Jun 2021

The Inducible lac Operator-Repressor System Is Functional in Zebrafish Cells

in Genomic Assay Technology

Sierra S. Nishizaki
Torrin L. McDonald
Gregory A. Farnum
Monica J. Holmes
Melissa L. Drexel
Jessica A. Switzenberg
Alan P. Boyle

Frontiers in Genetics

doi 10.3389/fgene.2021.683394

7,519 views

Original Research

Published on 17 Jun 2021

Expression and Clinical Significance of HKII and HIF-1α in Grade Groups of Prostate Cancer

in Genomic Assay Technology

Xueqi Sun
Qirui Huang
Fang Peng
Jian Wang
Weidong Zhao
Guangxiu Guo

Frontiers in Genetics

doi 10.3389/fgene.2021.680928

4,265 views
12 citations

Correction

Published on 15 Jun 2021

Corrigendum: Sequence and Structure Characteristics of 22 Deletion Breakpoints in Intron 44 of the DMD Gene Based on Long-Read Sequencing

in Genomic Assay Technology

Chang Geng
Yuanren Tong
Siwen Zhang
Chao Ling
Xin Wu
Depeng Wang
Yi Dai

Frontiers in Genetics

doi 10.3389/fgene.2021.706540

1,783 views

Methods

Published on 03 Jun 2021

A Scalable Strand-Specific Protocol Enabling Full-Length Total RNA Sequencing From Single Cells

in Genomic Assay Technology

Simon Haile
Richard D. Corbett
Veronique G. LeBlanc
Lisa Wei
Stephen Pleasance
Steve Bilobram
Ka Ming Nip
Kirstin Brown
Eva Trinh
Jillian Smith

Frontiers in Genetics

doi 10.3389/fgene.2021.665888

11,337 views
7 citations

Review

Published on 26 May 2021

Cancer Biomarkers Discovery of Methylation Modification With Direct High-Throughput Nanopore Sequencing

in Genomic Assay Technology

Junjie Zhang
Shuilian Xie
Jingxiang Xu
Hui Liu
Shaogui Wan

Frontiers in Genetics

doi 10.3389/fgene.2021.672804

13,643 views
26 citations

Original Research

Published on 20 May 2021

Guideline-Adherent Clinical Validation of a Comprehensive 170-Gene DNA/RNA Panel for Determination of Small Variants, Copy Number Variations, Splice Variants, and Fusions on a Next-Generation Sequencing Platform in the CLIA Setting

in Genomic Assay Technology

Theresa A. Boyle
Ashis K. Mondal
Daryoush Saeed-Vafa
Sudha Ananth
Pankaj Ahluwalia
Ravi Kothapalli
Alka Chaubey
Evans Roberts
Dahui Qin
Anthony M. Magliocco

Frontiers in Genetics

doi 10.3389/fgene.2021.503830

13,336 views
23 citations

Original Research

Published on 19 May 2021

Follow-up in Patients With Non-invasive Prenatal Screening Failures: A Reflection on the Choice of Further Prenatal Diagnosis

in Genomic Assay Technology

Sha Liu
Hongqian Liu
Jianlong Liu
Ting Bai
Xiaosha Jing
Tianyu Xia
Cechuan Deng
Yunyun Liu
Jing Cheng
Xiang Wei

Frontiers in Genetics

doi 10.3389/fgene.2021.666648

7,403 views
7 citations

Review

Published on 12 May 2021

Nanoparticle Delivery of CRISPR/Cas9 for Genome Editing

in Genomic Assay Technology

Li Duan
Kan Ouyang
Xiao Xu
Limei Xu
Caining Wen
Xiaoying Zhou
Zhuan Qin
Zhiyi Xu
Wei Sun
Yujie Liang

Frontiers in Genetics

doi 10.3389/fgene.2021.673286

84,603 views
295 citations

Original Research

Published on 11 May 2021

A Streamlined Approach to Prader-Willi and Angelman Syndrome Molecular Diagnostics

in Genomic Assay Technology

Samuel P. Strom
Waheeda A. Hossain
Melina Grigorian
Mickey Li
Joseph Fierro
William Scaringe
Hai-Yun Yen
Mirandy Teguh
Joanna Liu
Harry Gao

Frontiers in Genetics

doi 10.3389/fgene.2021.608889

8,815 views
28 citations

Original Research

Published on 30 Apr 2021

Sequence and Structure Characteristics of 22 Deletion Breakpoints in Intron 44 of the DMD Gene Based on Long-Read Sequencing

in Genomic Assay Technology

Chang Geng
Yuanren Tong
Siwen Zhang
Chao Ling
Xin Wu
Depeng Wang
Yi Dai

Frontiers in Genetics

doi 10.3389/fgene.2021.638220

6,757 views
11 citations

Original Research

Published on 21 Apr 2021

Cryopreservation Preserves Cell-Type Composition and Gene Expression Profiles in Bone Marrow Aspirates From Multiple Myeloma Patients

in Genomic Assay Technology

Duojiao Chen
Mohammad I. Abu Zaid
Jill L. Reiter
Magdalena Czader
Lin Wang
Patrick McGuire
Xiaoling Xuei
Hongyu Gao
Kun Huang
Rafat Abonour

Frontiers in Genetics

doi 10.3389/fgene.2021.663487

12,669 views
22 citations

Review

Published on 20 Apr 2021

Advances in Genome Editing and Application to the Generation of Genetically Modified Rat Models

in Genomic Assay Technology

Vanessa Chenouard
Séverine Remy
Laurent Tesson
Séverine Ménoret
Laure-Hélène Ouisse
Yacine Cherifi
Ignacio Anegon

Frontiers in Genetics

doi 10.3389/fgene.2021.615491

21,164 views
47 citations

Original Research

Published on 01 Apr 2021

CRISPR/Cas9-Mediated α-ENaC Knockout in a Murine Pancreatic β-Cell Line

in Genomic Assay Technology

Xue Zhang
Lihua Zhao
Runbing Jin
Min Li
Mei-Shuang Li
Rongfeng Li
Xiubin Liang

Frontiers in Genetics

doi 10.3389/fgene.2021.664799

6,076 views
6 citations

Original Research

Published on 24 Mar 2021

Comprehensive Pathogen Identification, Antibiotic Resistance, and Virulence Genes Prediction Directly From Simulated Blood Samples and Positive Blood Cultures by Nanopore Metagenomic Sequencing

in Genomic Assay Technology

Menglan Zhou
Yarong Wu
Timothy Kudinha
Peiyao Jia
Lei Wang
Yingchun Xu
Qiwen Yang

Frontiers in Genetics

doi 10.3389/fgene.2021.620009

12,284 views
34 citations

Original Research

Published on 10 Mar 2021

The Integration Preference of Sleeping Beauty at Non-TA Site Is Related to the Transposon End Sequences

in Genomic Assay Technology

Yiting Zhou
Guangwei Ma
Jiawen Yang
Zenghong Gao
Yabin Guo

Frontiers in Genetics

doi 10.3389/fgene.2021.639125

4,695 views
2 citations

Review

Published on 05 Mar 2021

Practical Approaches for Knock-Out Gene Editing in Pigs

in Genomic Assay Technology

Laura Daniela Ratner
Gaston Emilio La Motta
Olinda Briski
Daniel Felipe Salamone
Rafael Fernandez-Martin

Frontiers in Genetics

doi 10.3389/fgene.2020.617850

12,025 views
9 citations

Original Research

Published on 04 Mar 2021

Targeted RNA-Based Oxford Nanopore Sequencing for Typing 12 Classical HLA Genes

in Genomic Assay Technology

Tiira Johansson
Satu Koskela
Dawit A. Yohannes
Jukka Partanen
Päivi Saavalainen

Frontiers in Genetics

doi 10.3389/fgene.2021.635601

12,218 views
9 citations

Original Research

Published on 25 Feb 2021

Bisulfite-Converted DNA Quantity Evaluation: A Multiplex Quantitative Real-Time PCR System for Evaluation of Bisulfite Conversion

in Genomic Assay Technology

Sae Rom Hong
Kyoung-Jin Shin

Frontiers in Genetics

doi 10.3389/fgene.2021.618955

23,612 views
48 citations

Methods

Published on 05 Feb 2021

RNA Based Approaches to Profile Oncogenic Pathways From Low Quantity Samples to Drive Precision Oncology Strategies

in Genomic Assay Technology

Anja van de Stolpe
Wim Verhaegh
Jean-Yves Blay
Cynthia X. Ma
Patrick Pauwels
Mark Pegram
Hans Prenen
Dirk De Ruysscher
Nabil F. Saba
Susan F. Slovin

Frontiers in Genetics

doi 10.3389/fgene.2020.598118

5,948 views
28 citations

Review

Published on 02 Feb 2021

Genetically Modified Rabbits for Cardiovascular Research

in Genomic Assay Technology

Jianglin Fan
Yanli Wang
Y. Eugene Chen

Frontiers in Genetics

doi 10.3389/fgene.2021.614379

18,297 views
20 citations

253 articles

articles

Role of the kdpDE Regulatory Operon of Mycobacterium tuberculosis in Modulating Bacterial Growth in vitro

mRBioM: An Algorithm for the Identification of Potential mRNA Biomarkers From Complete Transcriptomic Profiles of Gastric Adenocarcinoma

The Optimal Cutoff Value of Z-scores Enhances the Judgment Accuracy of Noninvasive Prenatal Screening

Comprehensive Evaluation of Non-invasive Prenatal Screening to Detect Fetal Copy Number Variations

The Inducible lac Operator-Repressor System Is Functional in Zebrafish Cells

Expression and Clinical Significance of HKII and HIF-1α in Grade Groups of Prostate Cancer

Corrigendum: Sequence and Structure Characteristics of 22 Deletion Breakpoints in Intron 44 of the DMD Gene Based on Long-Read Sequencing

A Scalable Strand-Specific Protocol Enabling Full-Length Total RNA Sequencing From Single Cells

Cancer Biomarkers Discovery of Methylation Modification With Direct High-Throughput Nanopore Sequencing

Guideline-Adherent Clinical Validation of a Comprehensive 170-Gene DNA/RNA Panel for Determination of Small Variants, Copy Number Variations, Splice Variants, and Fusions on a Next-Generation Sequencing Platform in the CLIA Setting

Follow-up in Patients With Non-invasive Prenatal Screening Failures: A Reflection on the Choice of Further Prenatal Diagnosis

Nanoparticle Delivery of CRISPR/Cas9 for Genome Editing

A Streamlined Approach to Prader-Willi and Angelman Syndrome Molecular Diagnostics

Sequence and Structure Characteristics of 22 Deletion Breakpoints in Intron 44 of the DMD Gene Based on Long-Read Sequencing

Cryopreservation Preserves Cell-Type Composition and Gene Expression Profiles in Bone Marrow Aspirates From Multiple Myeloma Patients

Advances in Genome Editing and Application to the Generation of Genetically Modified Rat Models

CRISPR/Cas9-Mediated α-ENaC Knockout in a Murine Pancreatic β-Cell Line

Comprehensive Pathogen Identification, Antibiotic Resistance, and Virulence Genes Prediction Directly From Simulated Blood Samples and Positive Blood Cultures by Nanopore Metagenomic Sequencing

The Integration Preference of Sleeping Beauty at Non-TA Site Is Related to the Transposon End Sequences

Practical Approaches for Knock-Out Gene Editing in Pigs

Targeted RNA-Based Oxford Nanopore Sequencing for Typing 12 Classical HLA Genes

Bisulfite-Converted DNA Quantity Evaluation: A Multiplex Quantitative Real-Time PCR System for Evaluation of Bisulfite Conversion

RNA Based Approaches to Profile Oncogenic Pathways From Low Quantity Samples to Drive Precision Oncology Strategies

Genetically Modified Rabbits for Cardiovascular Research