Frontiers in Genetics | Genomic Assay Technology

Methods

Published on 05 Feb 2021

RNA Based Approaches to Profile Oncogenic Pathways From Low Quantity Samples to Drive Precision Oncology Strategies

in Genomic Assay Technology

Anja van de Stolpe
Wim Verhaegh
Jean-Yves Blay
Cynthia X. Ma
Patrick Pauwels
Mark Pegram
Hans Prenen
Dirk De Ruysscher
Nabil F. Saba
Susan F. Slovin

Frontiers in Genetics

doi 10.3389/fgene.2020.598118

5,016 views
26 citations

Review

Published on 02 Feb 2021

Genetically Modified Rabbits for Cardiovascular Research

in Genomic Assay Technology

Jianglin Fan
Yanli Wang
Y. Eugene Chen

Frontiers in Genetics

doi 10.3389/fgene.2021.614379

16,012 views
14 citations

Brief Research Report

Published on 01 Feb 2021

Allelic Dropout Is a Common Phenomenon That Reduces the Diagnostic Yield of PCR-Based Sequencing of Targeted Gene Panels

in Genomic Assay Technology

Anna G. Shestak
Anna A. Bukaeva
Siamak Saber
Elena V. Zaklyazminskaya

Frontiers in Genetics

doi 10.3389/fgene.2021.620337

32,719 views
39 citations

Review

Published on 28 Jan 2021

Gene Editing in Rabbits: Unique Opportunities for Translational Biomedical Research

in Genomic Assay Technology

Jie Xu
Jifeng Zhang
Dongshan Yang
Jun Song
Brooke Pallas
Chen Zhang
Jiafen Hu
Xuwen Peng
Neil D. Christensen
Renzhi Han

Frontiers in Genetics

doi 10.3389/fgene.2021.642444

9,594 views
15 citations

Original Research

Published on 28 Jan 2021

Targeted Gene Editing in Porcine Spermatogonia

in Genomic Assay Technology

Dennis Webster
Alla Bondareva
Staci Solin
Taylor Goldsmith
Lin Su
Nathalia de Lima e Martins Lara
Daniel F. Carlson
Ina Dobrinski

Frontiers in Genetics

doi 10.3389/fgene.2020.627673

4,544 views
4 citations

Original Research

Published on 22 Jan 2021

Production of CFTR-ΔF508 Rabbits

in Genomic Assay Technology

Dongshan Yang
Xiubin Liang
Brooke Pallas
Mark Hoenerhoff
Zhuoying Ren
Renzhi Han
Jifeng Zhang
Y. Eugene Chen
Jian-Ping Jin
Fei Sun

Frontiers in Genetics

doi 10.3389/fgene.2020.627666

4,946 views
13 citations

Methods

Published on 12 Jan 2021

Detection of Mitochondrial Mutations Through Isothermal Nucleic Acid Amplification Coupled With Clustered Regularly Interspaced Short Palindromic Repeat-Associated Endonuclease Cas13a

in Genomic Assay Technology

Hua Jiang
Kun Duan
Xu Han
Jun Wang
Xiao Liu
Maoxiao Yan
Yunxiu Wang
Hongyan Liu
Huiling Shi
Xiaoqing Gao

Frontiers in Genetics

doi 10.3389/fgene.2020.622671

3,284 views
4 citations

Review

Published on 08 Jan 2021

Improvements in Gene Editing Technology Boost Its Applications in Livestock

in Genomic Assay Technology

Iuri Viotti Perisse
Zhiqiang Fan
Galina N. Singina
Kenneth L. White
Irina A. Polejaeva

Frontiers in Genetics

doi 10.3389/fgene.2020.614688

31,029 views
56 citations

Original Research

Published on 07 Jan 2021

Analysis of Wild Type LbCpf1 Protein, and PAM Recognition Variants, in a Cellular Context

in Genomic Assay Technology

Ujin Shin
Vincent Brondani

Frontiers in Genetics

doi 10.3389/fgene.2020.571591

5,656 views
3 citations

Brief Research Report

Published on 01 Dec 2020

A Distributed Whole Genome Sequencing Benchmark Study

in Genomic Assay Technology

Richard D. Corbett
Robert Eveleigh
Joe Whitney
Namrata Barai
Mathieu Bourgey
Eric Chuah
Joanne Johnson
Richard A. Moore
Neda Moradin
Karen L. Mungall

Frontiers in Genetics

doi 10.3389/fgene.2020.612515

8,016 views
8 citations

Original Research

Published on 30 Nov 2020

Generation of Multi-Transgenic Pigs Using PiggyBac Transposons Co-expressing Pectinase, Xylanase, Cellulase, β-1.3-1.4-Glucanase and Phytase

in Genomic Assay Technology

Haoqiang Wang
Guoling Li
Cuili Zhong
Jianxin Mo
Yue Sun
Junsong Shi
Rong Zhou
Zicong Li
Zhenfang Wu
Dewu Liu

Frontiers in Genetics

doi 10.3389/fgene.2020.597841

4,535 views
3 citations

Review

Published on 27 Nov 2020

Applications of Single-Cell Omics to Dissect Tumor Microenvironment

in Genomic Assay Technology

Tingting Guo
Weimin Li
Xuyu Cai

Frontiers in Genetics

doi 10.3389/fgene.2020.548719

8,146 views
24 citations

Original Research

Published on 04 Nov 2020

EC-PGMGR: Ensemble Clustering Based on Probability Graphical Model With Graph Regularization for Single-Cell RNA-seq Data

in Genomic Assay Technology

Yuan Zhu
De-Xin Zhang
Xiao-Fei Zhang
Ming Yi
Le Ou-Yang
Mengyun Wu

Frontiers in Genetics

doi 10.3389/fgene.2020.572242

2,745 views
7 citations

Methods

Published on 14 Oct 2020

Application of FF-QuantSC for the Precise Estimation of Fetal Fraction in Non-invasive Prenatal Testing in Two SRY-Translocation Cases

in Genomic Assay Technology

Yan Zeng
Jiong Gao
Hua Yuan
Lijun Zhou
Dehua Cheng
Ming Che
Yandi Qian
Jiaming Fan
Lifang Zhang
Feiyan Qian

Frontiers in Genetics

doi 10.3389/fgene.2020.570333

3,509 views
4 citations

Original Research

Published on 09 Oct 2020

Patterns, Profiles, and Parsimony: Dissecting Transcriptional Signatures From Minimal Single-Cell RNA-Seq Output With SALSA

in Genomic Assay Technology

Oswaldo A. Lozoya
Kathryn S. McClelland
Brian N. Papas
Jian-Liang Li
Humphrey H.-C. Yao

Frontiers in Genetics

doi 10.3389/fgene.2020.511286

5,224 views
1 citation

Methods

Published on 06 Oct 2020

NeuralEE: A GPU-Accelerated Elastic Embedding Dimensionality Reduction Method for Visualizing Large-Scale scRNA-Seq Data

in Genomic Assay Technology

Jiankang Xiong
Fuzhou Gong
Lin Wan
Liang Ma

Frontiers in Genetics

doi 10.3389/fgene.2020.00786

5,901 views
2 citations