Frontiers in Genetics | Pharmacogenetics and Pharmacogenomics

Review

Published on 24 Jun 2025

Gene polymorphisms associated with immunosuppressant adverse effects in systemic lupus erythematosus: a narrative review

in Pharmacogenetics and Pharmacogenomics

Siva Hamdani
Laniyati Hamijoyo
Riezki Amalia
Melisa I. Barliana

Frontiers in Genetics

doi 10.3389/fgene.2025.1594648

589 views

Case Report

Published on 17 Jun 2025

Case Report: Successful late-line pralsetinib treatment in an ALK-rearranged lung adenocarcinoma patient with KIF5B-RET fusion resistant to alectinib

in Pharmacogenetics and Pharmacogenomics

Feng Jin
Chenyang Wang
Fang Yang
Shubin Wang
Fen Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1569912

435 views

Original Research

Published on 04 Jun 2025

NOS3 rs3918188C>A is associated with susceptibility to resistant hypertension while CES1 genetic variation was not associated with resistant hypertension among South Africans

in Pharmacogenetics and Pharmacogenomics

Jonathan N. Katsukunya
Revina Naicker
Nyarai D. Soko
Dirk Blom
Phumla Sinxadi
Emile R. Chimusa
Brian Rayner
Erika Jones
Collet Dandara

Frontiers in Genetics

doi 10.3389/fgene.2025.1608423

1,485 views

Original Research

Published on 29 May 2025

Clinical impact of pharmacogenomics in pediatric care: insights extracted from clinical exome sequencing

in Pharmacogenetics and Pharmacogenomics

Simran Maggo
Yachen Pan
Dejerianne Ostrow
Jenny Q. Nguyen
Jaclyn A. Biegel
Matthew A. Deardorff
Xiaowu Gai

Frontiers in Genetics

doi 10.3389/fgene.2025.1574325

1,510 views

Original Research

Published on 20 May 2025

Lack of association between genetic variations in CYP3A5 and blood pressure or hypertension risk in the UK biobank

in Pharmacogenetics and Pharmacogenomics

Pia Leibold
Christelle Lteif
Julio D. Duarte

Frontiers in Genetics

doi 10.3389/fgene.2025.1490863

879 views

Review

Published on 30 Apr 2025

Leveraging long-read sequencing technologies for pharmacogenomic testing: applications, analytical strategies, challenges, and future perspectives

in Pharmacogenetics and Pharmacogenomics

Alireza Tafazoli
Mahboobeh Hemmati
Mahboobeh Rafigh
Maliheh Alimardani
Faeze Khaghani
Michał Korostyński
Jason H. Karnes

Frontiers in Genetics

doi 10.3389/fgene.2025.1435416

1,690 views
1 citation

Original Research

Published on 17 Apr 2025

Correlation between gene polymorphisms and perioperative analgesia in patients undergoing gynecological surgery

in Pharmacogenetics and Pharmacogenomics

Meng Cai
Xiaofeng Lei
Lin Gan
Jing Li
Jin Yu

Frontiers in Genetics

doi 10.3389/fgene.2025.1509042

910 views

Systematic Review

Published on 20 Feb 2025

Correlation and clinical significance of GSTP1 hypermethylation in hepatocellular carcinoma: a systematic review and meta-analysis

in Pharmacogenetics and Pharmacogenomics

Pengfei Li
Lei He
Chunxia Zhang
Xinyao Huang
Rong Sun
Yan Zhang
Yan Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1543261

1,547 views

Original Research

Published on 23 Oct 2024

Roles of NR1I3 and NR1H4 polymorphisms in the susceptibility to antituberculosis drug-induced liver injury in China: a case‒control study

in Pharmacogenetics and Pharmacogenomics

Xiaoyan Xu
Ruina Chen
Lihuan Lu
Jingru Cheng
Xiaomin He
Hongqiu Pan
Meiling Zhang
Honggang Yi
Shaowen Tang

Frontiers in Genetics

doi 10.3389/fgene.2024.1428319

1,230 views

Original Research

Published on 11 Sep 2024

Ninein, a candidate gene for ethanol anxiolysis, shows complex exon-specific expression and alternative splicing differences between C57BL/6J and DBA/2J mice

in Pharmacogenetics and Pharmacogenomics

E. R. Gnatowski
J. L. Jurmain
M. G. Dozmorov
J. T. Wolstenholme
M. F. Miles

Frontiers in Genetics

doi 10.3389/fgene.2024.1455616

1,285 views
1 citation

Mini Review

Published on 30 Aug 2024

Human sulfotransferase SULT2B1 physiological role and the impact of genetic polymorphism on enzyme activity and pathological conditions

in Pharmacogenetics and Pharmacogenomics

Fatemah A. Alherz

Frontiers in Genetics

doi 10.3389/fgene.2024.1464243

2,232 views
4 citations

Editorial

Published on 20 Aug 2024

Editorial: Utilization of pharmacogenomics in clinical practice

in Pharmacogenetics and Pharmacogenomics

Apostolos Papachristos
Jessica Cusato
Sujit Nair
Simran Maggo
Vijayaprakash Suppiah

Frontiers in Genetics

doi 10.3389/fgene.2024.1470698

1,271 views

Editorial

Published on 18 Apr 2024

Editorial: The impact of the human genome on interindividual variability in drug response

in Pharmacogenetics and Pharmacogenomics

Yaya Kassogue
Ingrid Fricke-Galindo

Frontiers in Genetics

doi 10.3389/fgene.2024.1401604

1,535 views

Editorial

Published on 03 Apr 2024

Editorial: Molecular targets for anticancer drug discovery and development

in Pharmacogenetics and Pharmacogenomics

Monde Ntwasa
Zodwa Dlamini

Frontiers in Genetics

doi 10.3389/fgene.2024.1374867

1,541 views

Original Research

Published on 05 Jan 2024

Phylogenetic conservation of Trop-2 across species—rodent and primate genomics model anti-Trop-2 therapy for pre-clinical benchmarks

in Pharmacogenetics and Pharmacogenomics

Emanuela Guerra
Marco Trerotola
Valeria Relli
Rossano Lattanzio
Khouloud Boujnah
Nicole Travali
Antonino Moschella
Paolo Todaro
Laura Pierdomenico
Roberta Di Pietro

Frontiers in Genetics

doi 10.3389/fgene.2023.1297367

4,361 views
1 citation

Mini Review

Published on 03 Jan 2024

Moving towards the implementation of pharmacogenetic testing in Quebec

in Pharmacogenetics and Pharmacogenomics

Ling Jing Li
Samuel Legeay
Ann-Lorie Gagnon
Marie-Pier Frigon
Laurence Tessier
Karine Tremblay

Frontiers in Genetics

doi 10.3389/fgene.2023.1295963

3,351 views
3 citations