Frontiers in Genetics | Pharmacogenetics and Pharmacogenomics

Review

Published on 01 Feb 2013

Clinical Application of CYP2C19 Pharmacogenetics Toward More Personalized Medicine

in Pharmacogenetics and Pharmacogenomics

Su-Jun Lee

Frontiers in Genetics

doi 10.3389/fgene.2012.00318

25,643 views
80 citations

Review

Published on 22 Jan 2013

Molecular Interactions between NAFLD and Xenobiotic Metabolism

in Pharmacogenetics and Pharmacogenomics

Adviti Naik
Aleš Belič
Ulrich M Zanger
Damjana Rozman

Frontiers in Genetics

doi 10.3389/fgene.2013.00002

11,375 views
57 citations

Review

Published on 22 Jan 2013

Functional Polymorphisms in Xenobiotic Metabolizing Enzymes and Their Impact on the Therapy of Breast Cancer

in Pharmacogenetics and Pharmacogenomics

Rosane Vianna-Jorge
Juliana Festa-Vasconcellos
Sheyla Mria Torres Goulart-Citrangulo
Marcelo Sobral Leite

Frontiers in Genetics

doi 10.3389/fgene.2012.00329

6,073 views
10 citations

Original Research

Published on 17 Jan 2013

High-resolution melting analysis of the common c.1905+1G>A mutation causing dihydropyrimidine dehydrogenase deficiency and lethal 5-fluorouracil toxicity

in Pharmacogenetics and Pharmacogenomics

Emma Borràs
Emma Dotor
Àngels Arcusa
Maria José Gamundi
Imma Hernan
Miguel de Sousa Dias
Begoña Mañé
José A G Agúndez
Miguel Blanca
Miguel Carballo

Frontiers in Genetics

doi 10.3389/fgene.2012.00312

7,776 views
11 citations

Review

Published on 07 Jan 2013

Multilocus Genotypes of Relevance for Drug Metabolizing Enzymes and Therapy with Thiopurines in Patients with Acute Lymphoblastic Leukemia

in Pharmacogenetics and Pharmacogenomics

Gabriele Stocco
Raffaella Franca
Federico Verzegnassi
Margherita Londero
Marco Rabusin
Giuliana Decorti

Frontiers in Genetics

doi 10.3389/fgene.2012.00309

5,380 views
15 citations

Review

Published on 02 Jan 2013

Pharmacogenetics of human ABC transporter ABCC11: new insights into apocrine gland growth and metabolite secretion

in Pharmacogenetics and Pharmacogenomics

Toshihisa Ishikawa
Yu Toyoda
Koh-ichiro Yoshiura
Norio Niikawa

Frontiers in Genetics

doi 10.3389/fgene.2012.00306

51,658 views
37 citations

Original Research

Published on 03 Dec 2012

Analysis of the Functional Polymorphism in the Cytochrome P450 CYP2C8 Gene rs11572080 with Regard to Colorectal Cancer Risk

in Pharmacogenetics and Pharmacogenomics

José M Ladero
José A G Agúndez
Carmen Martínez
Gemma Amo
Pedro Ayuso
Elena García-Martín

Frontiers in Genetics

doi 10.3389/fgene.2012.00278

4,735 views
11 citations

Review

Published on 28 Nov 2012

Polymorphisms of Phase I and Phase II Enzymes and Breast Cancer Risk

in Pharmacogenetics and Pharmacogenomics

Christina Justenhoven

Frontiers in Genetics

doi 10.3389/fgene.2012.00258

8,656 views
13 citations

Perspective

Published on 26 Nov 2012

Toward a clinical practice guide in pharmacogenomics testing for functional polymorphisms of drug-metabolizing enzymes. Gene/drug pairs and barriers perceived in Spain

in Pharmacogenetics and Pharmacogenomics

José A G Agúndez
Francisco Abad-Santos
Ana Aldea
Hortensia Alonso
María Luisa Bernal
Alberto Borobia
Emma Borras
Miguel Carballo
Alfonso Carvajal
José D García-Muñiz

Frontiers in Genetics

doi 10.3389/fgene.2012.00273

8,736 views
24 citations

Review

Published on 22 Nov 2012

Impact of genetic polymorphisms on chemotherapy toxicity in childhood acute lymphoblastic leukemia

in Pharmacogenetics and Pharmacogenomics

Guillermo Gervasini
Jose Manuel Vagace

Frontiers in Genetics

doi 10.3389/fgene.2012.00249

16,266 views
36 citations

Original Research

Published on 21 Nov 2012

Impact of the Interaction between 3′-UTR SNPs and microRNA on the Expression of Human Xenobiotic Metabolism Enzyme and Transporter Genes

in Pharmacogenetics and Pharmacogenomics

Rongrong Wei
Fan Yang
Thomas J. Urban
Lang Li
Naga Chalasani
David A Flockhart
Wanqing Liu

Frontiers in Genetics

doi 10.3389/fgene.2012.00248

8,557 views
34 citations

Opinion

Published on 16 Nov 2012

Genetic variations in drug-induced liver injury (DILI): resolving the puzzle

in Pharmacogenetics and Pharmacogenomics

Camilla Stephens
M Isabel Lucena
Raúl J Andrade

Frontiers in Genetics

doi 10.3389/fgene.2012.00253

4,904 views
12 citations

Review

Published on 12 Nov 2012

MDMA, methamphetamine, and CYP2D6 pharmacogenetics: what is clinically relevant?

in Pharmacogenetics and Pharmacogenomics

Rafael De La Torre
Samanta Yubero-Lahoz
Ricardo Pardo-Lozano
Magi Farre

Frontiers in Genetics

doi 10.3389/fgene.2012.00235

69,355 views
87 citations

Original Research

Published on 05 Nov 2012

ABCB1 4036A>G and 1236C>T Polymorphisms Affect Plasma Efavirenz Levels in South African HIV/AIDS Patients

in Pharmacogenetics and Pharmacogenomics

Marelize Swart
Yuan Ren
Peter Smith
Collet Dandara

Frontiers in Genetics

doi 10.3389/fgene.2012.00236

6,880 views
51 citations

Original Research

Published on 02 Nov 2012

Frequencies of 23 Functionally Significant Variant Alleles Related with Metabolism of Antineoplastic Drugs in the Chilean Population: Comparison with Caucasian and Asian Populations

in Pharmacogenetics and Pharmacogenomics

Angela Margarita Roco
Luis Abel Quiñones
José A G Agúndez
Elena García-Martín
Valentina Squicciarini
Carla Estefania Miranda
Joselyn Garay
Nancy Farfán
Iván Nicolás Saavedra
Dante Daniel Caceres

Frontiers in Genetics

doi 10.3389/fgene.2012.00229

10,697 views
68 citations

Review

Published on 10 Oct 2012

Molecular mechanisms of genetic variation and transcriptional regulation of CYP2C19

in Pharmacogenetics and Pharmacogenomics

Nuala Ann Helsby
Kathryn Elisa Burns

Frontiers in Genetics

doi 10.3389/fgene.2012.00206

9,651 views
30 citations