Frontiers in Genetics | Toxicogenomics

Original Research

Published on 11 Jan 2022

Sea Anemones Responding to Sex Hormones, Oxybenzone, and Benzyl Butyl Phthalate: Transcriptional Profiling and in Silico Modelling Provide Clues to Decipher Endocrine Disruption in Cnidarians

in Toxicogenomics

Michael B. Morgan
James Ross
Joseph Ellwanger
Rebecca Martin Phrommala
Hannah Youngblood
Dominic Qualley
Jacob Williams

Frontiers in Genetics

doi 10.3389/fgene.2021.793306

6,007 views
6 citations

Review

Published on 09 Dec 2021

Two-Way Development of the Genetic Model for Endometrial Tumorigenesis in Mice: Current and Future Perspectives

in Toxicogenomics

Yoshiaki Maru
Yoshitaka Hippo

Frontiers in Genetics

doi 10.3389/fgene.2021.798628

6,072 views
8 citations

Original Research

Published on 29 Nov 2021

The Unique Genetic and Histological Characteristics of DMBA-Induced Mammary Tumors in an Organoid-Based Carcinogenesis Model

in Toxicogenomics

Mie Naruse
Rikako Ishigamori
Toshio Imai

Frontiers in Genetics

doi 10.3389/fgene.2021.765131

5,197 views
3 citations

Original Research

Published on 18 Nov 2021

Establishment of Novel Genotoxicity Assay System Using Murine Normal Epithelial Tissue-Derived Organoids

in Toxicogenomics

Masami Komiya
Rikako Ishigamori
Mie Naruse
Masako Ochiai
Noriyuki Miyoshi
Toshio Imai
Yukari Totsuka

Frontiers in Genetics

doi 10.3389/fgene.2021.768781

3,410 views
5 citations

Original Research

Published on 11 Nov 2021

Converging Effects of Three Different Endocrine Disrupters on Sox and Pou Gene Expression in Developing Rat Hippocampus: Possible Role of microRNA in Sex Differences

in Toxicogenomics

Walter Lichtensteiger
Catherine Bassetti-Gaille
Hubert Rehrauer
Jelena Kühn Georgijevic
Jesus A.F. Tresguerres
Margret Schlumpf

Frontiers in Genetics

doi 10.3389/fgene.2021.718796

3,201 views
6 citations

Review

Published on 01 Nov 2021

Human Organoids for Predictive Toxicology Research and Drug Development

in Toxicogenomics

Toshikatsu Matsui
Tadahiro Shinozawa

Frontiers in Genetics

doi 10.3389/fgene.2021.767621

19,802 views
72 citations

Review

Published on 22 Oct 2021

Human Organoid and Supporting Technologies for Cancer and Toxicological Research

in Toxicogenomics

Keisuke Sekine

Frontiers in Genetics

doi 10.3389/fgene.2021.759366

5,375 views
5 citations

Review

Published on 29 Sep 2021

Genotoxic Potential of Nanoparticles: Structural and Functional Modifications in DNA

in Toxicogenomics

Ritesh K Shukla
Ashish Badiye
Kamayani Vajpayee
Neeti Kapoor

Frontiers in Genetics

doi 10.3389/fgene.2021.728250

10,906 views
67 citations

Mini Review

Published on 29 Sep 2021

Health Effects Associated With Pre- and Perinatal Exposure to Arsenic

in Toxicogenomics

Victor D. Martinez
Wan L. Lam

Frontiers in Genetics

doi 10.3389/fgene.2021.664717

5,569 views
34 citations

Review

Published on 27 Sep 2021

Overview of the Mechanisms of Action of Selected Bisphenols and Perfluoroalkyl Chemicals on the Male Reproductive Axes

in Toxicogenomics

Michal Ješeta
Jana Navrátilová
Kateřina Franzová
Sandra Fialková
Bartozs Kempisty
Pavel Ventruba
Jana Žáková
Igor Crha

Frontiers in Genetics

doi 10.3389/fgene.2021.692897

9,932 views
24 citations

Original Research

Published on 27 Sep 2021

Lipidomic Analyses Reveal Modulation of Lipid Metabolism by the PFAS Perfluoroundecanoic Acid (PFUnDA) in Non-Obese Diabetic Mice

in Toxicogenomics

Tuulia Hyötyläinen
Johanna Bodin
Daniel Duberg
Hubert Dirven
Unni C. Nygaard
Matej Orešič

Frontiers in Genetics

doi 10.3389/fgene.2021.721507

7,127 views
12 citations

Systematic Review

Published on 17 Aug 2021

The Role of Mitochondrial DNA Variation in Drug Response: A Systematic Review

in Toxicogenomics

Samantha W. Jones
Amy L. Ball
Amy E. Chadwick
Ana Alfirevic

Frontiers in Genetics

doi 10.3389/fgene.2021.698825

10,529 views
18 citations

Original Research

Published on 05 Aug 2021

Integrated Analysis of mRNA- and miRNA-Seq in the Ovary of Rare Minnow Gobiocypris rarus in Response to 17α-Methyltestosterone

in Toxicogenomics

Shaozhen Liu
Qiong Yang
Yue Chen
Qing Liu
Weiwei Wang
Jing Song
Yao Zheng
Wenzhong Liu

Frontiers in Genetics

doi 10.3389/fgene.2021.695699

3,157 views
6 citations

Original Research

Published on 04 Aug 2021

Dysregulation of Cells Cycle and Apoptosis in Human Induced Pluripotent Stem Cells Chondrocytes Through p53 Pathway by HT-2 Toxin: An in vitro Study

in Toxicogenomics

Yanan Zhang
Huan Liu
Xialu Lin
Feng’e Zhang
Peilin Meng
Sijia Tan
Mikko J. Lammi
Xiong Guo

Frontiers in Genetics

doi 10.3389/fgene.2021.677723

3,034 views
6 citations

Original Research

Published on 03 Aug 2021

Genetic Expression Screening of Arsenic Trioxide-Induced Cytotoxicity in KG-1a Cells Based on Bioinformatics Technology

in Toxicogenomics

Yahui Li
Yingjie Feng
Xiaohui Si
Chenjin Zhao
Fanping Wang
Xinqing Niu

Frontiers in Genetics

doi 10.3389/fgene.2021.654826

3,000 views
2 citations

Original Research

Published on 02 Aug 2021

Low-Dose Radiation Can Cause Epigenetic Alterations Associated With Impairments in Both Male and Female Reproductive Cells

in Toxicogenomics

Chi Tim Leung
Yi Yang
Kwan Ngok Yu
Nathan Tam
Ting Fung Chan
Xiao Lin
Richard Yuen Chong Kong
Jill Man Ying Chiu
Alice Sze Tsai Wong
Wing Yee Lui

Frontiers in Genetics

doi 10.3389/fgene.2021.710143

6,988 views
15 citations

Navigation group

Articles

Sea Anemones Responding to Sex Hormones, Oxybenzone, and Benzyl Butyl Phthalate: Transcriptional Profiling and in Silico Modelling Provide Clues to Decipher Endocrine Disruption in Cnidarians

Two-Way Development of the Genetic Model for Endometrial Tumorigenesis in Mice: Current and Future Perspectives

The Unique Genetic and Histological Characteristics of DMBA-Induced Mammary Tumors in an Organoid-Based Carcinogenesis Model

Establishment of Novel Genotoxicity Assay System Using Murine Normal Epithelial Tissue-Derived Organoids

Converging Effects of Three Different Endocrine Disrupters on Sox and Pou Gene Expression in Developing Rat Hippocampus: Possible Role of microRNA in Sex Differences

Human Organoids for Predictive Toxicology Research and Drug Development

Human Organoid and Supporting Technologies for Cancer and Toxicological Research

Genotoxic Potential of Nanoparticles: Structural and Functional Modifications in DNA

Health Effects Associated With Pre- and Perinatal Exposure to Arsenic

Overview of the Mechanisms of Action of Selected Bisphenols and Perfluoroalkyl Chemicals on the Male Reproductive Axes

Lipidomic Analyses Reveal Modulation of Lipid Metabolism by the PFAS Perfluoroundecanoic Acid (PFUnDA) in Non-Obese Diabetic Mice

The Role of Mitochondrial DNA Variation in Drug Response: A Systematic Review

Integrated Analysis of mRNA- and miRNA-Seq in the Ovary of Rare Minnow Gobiocypris rarus in Response to 17α-Methyltestosterone

Dysregulation of Cells Cycle and Apoptosis in Human Induced Pluripotent Stem Cells Chondrocytes Through p53 Pathway by HT-2 Toxin: An in vitro Study

Genetic Expression Screening of Arsenic Trioxide-Induced Cytotoxicity in KG-1a Cells Based on Bioinformatics Technology

Low-Dose Radiation Can Cause Epigenetic Alterations Associated With Impairments in Both Male and Female Reproductive Cells