Frontiers in Genetics

Case Report

Published on 10 Oct 2025

Case Report: Practical approach to differentiating juvenile parkinsonism of genetic cause and drug-induced parkinsonism in adolescents: a case series and literature review

Ioana Grigore
Lăcrămioara Ionela Butnariu
Thomas Gabriel Schreiner
Vasile Valeriu Lupu
Ancuta Lupu
Ludmila Darie
Cătălin Prăzaru
Elena Țarcă
Setalia Popa
Ecaterina Grigore

Frontiers in Genetics

doi 10.3389/fgene.2025.1672445

1,655 views

Editorial

Published on 09 Oct 2025

Editorial: Application of next-generation sequencing in clinical settings

Zhi Chai
Han Mei
Quan Li
Iram Maqsood
Jingxian Cai
Marilyn M. Li
Feng Xu
Xiaonan Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1700975

3,723 views

Original Research

Published on 09 Oct 2025

The molecular characterization of seven novel GLI family zinc finger 3 (GLI3) variants in Chinese families with limb malformations

Siyuan Tao
Xuyu Gu
Xiaodong Wang
Xiaofang Shen
Xiuli Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1650790

1,349 views

Original Research

Published on 08 Oct 2025

Integrated transcriptomic and single-cell RNA sequencing identifies lysosomal ion channel genes as potential biomarkers for Alzheimer’s disease

Xin Wang
Zelin Wu
Shaoli Wei
Xinran Zhao
Juan Lin
Fang Zhao
Xiaolei Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1676565

2,270 views

Original Research

Published on 08 Oct 2025

GTAT-GRN: a graph topology-aware attention method with multi-source feature fusion for gene regulatory network inference

Shuran Wang
Lilian Zhang
Lutao Gao
Yao Rao
Jie Cui
Linnan Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1668773

2,266 views

Data Report

Published on 08 Oct 2025

Catalogue of mitotic chromosome-associated small RNAs in mouse 3T3 cell line

Bishan Ye
Yicong Meng
Le Zhang
Yongzhuo Deng
Xuesong Zheng
Yihang Shen
Xinhui Li
Hua Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1559795

1,550 views

Perspective

Published on 08 Oct 2025

Ethical, legal, and policy dimensions and contentions for reanalysis and reinterpretation of clinical genetic testing results

Zachary T. Sentell
Ma’n H. Zawati

Frontiers in Genetics

doi 10.3389/fgene.2025.1685854

1,775 views

Review

Published on 08 Oct 2025

Epigenetic and metabolic reprogramming via nanotechnology: a synergistic approach to cancer vaccination in lung tumors

Min Xu
Xialin Zhang
Xinlin Yu
Cheng Ma
Xinwei Li
Gang Chen
Gang Yuan
Sheng Lin
Ran Cui

Frontiers in Genetics

doi 10.3389/fgene.2025.1666561

2,052 views
1 citation

Review

Published on 08 Oct 2025

NanoMarine therapeutics: a new wave in drug delivery from oceanic bioresources targeting colon cancer via miRNA modulation

Ramkumar Muthu
Rajkumar Manickam
Rajkumar Thamarai
Sivabalan Sivasamy
Karthikeyan Mahendran
Rajkumar Prabhakaran

Frontiers in Genetics

doi 10.3389/fgene.2025.1668618

3,544 views

Editorial

Published on 08 Oct 2025

Editorial: Genetics and justice: the implications of large-scale genome sequencing initiatives in the global south

Michel Satya Naslavsky
Tayyaba Jiwani
Ernesto Schwartz-Marin

Frontiers in Genetics

doi 10.3389/fgene.2025.1703507

1,596 views

Original Research

Published on 08 Oct 2025

Modulation of the lncRNA TCONS_00265853-miR-421-5p-CLOCK axis by Ziyin Buyang Formula in polycystic ovarian syndrome with circadian rhythm disruption: an integrated bioinformatics and experimental approach

Haixia Huang
Ling Sun
Fan Jia
Yong Tan
Yahong Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1658812

2,005 views

Brief Research Report

Published on 08 Oct 2025

A novel splicing variant in NBAS identified by minigene assay causes infantile liver failure syndrome type 2

Anna Hu
Jun Liang
Hongbo Liu
Jinghui Jiang
Fujing Xie
Xin Zhou
Xiaojia Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1687266

1,596 views

Original Research

Published on 08 Oct 2025

Pain - related methylation driver genes affect the prognosis of pancreatic cancer patients by altering immune function and perineural infiltration

Chencheng Zhang
Weiwei Xu
Xudong Chen
Xingdan Wang
Xiaopeng Cui
Wenjing Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1600883

2,331 views

Correction

Published on 07 Oct 2025

Correction: FEZF1-AS1 drives autophagy-mediated progression of colon cancer and reduces chemosensitivity through inhabiting the PI3K/AKT/mTOR signaling pathway

Xiaoping Yang
Zuohui Yuan
Lingzhu Gou
Long Cheng
Zirui Wang
Pingfan Wu
Xiaochun Wang
Xueni Ma
Tiantian Ma
Yi Yu

Frontiers in Genetics

doi 10.3389/fgene.2025.1684479

1,304 views

Original Research

Published on 07 Oct 2025

Identification of shared diagnostic genes between osteoporosis and Crohn’s disease through integrated transcriptomic analysis and machine learning

Guirong Yi
Peng Zhou
Qinxu Yang
Maosheng Zhao
Qiaoqiao Yang
Shensong Li
Chenpo Dang

Frontiers in Genetics

doi 10.3389/fgene.2025.1609915

2,233 views

Correction

Published on 07 Oct 2025

Correction: Multi-omics integration uncovers key transcriptional regulators in triple-negative breast cancer spatial heterogeneity

Ning Zhang
Ye Zhang
Rui-Fei Yang
Min Tan
Hai-Qing Chu
Abdur Rehman
Lu-Yu Yang
Ya-Yu Li
Fahad M. Alshabrmi
Xin Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1701926

1,196 views

Original Research

Published on 07 Oct 2025

A novel de novo IL2RG nonsense mutation in a pediatric patient with X-linked severe combined immunodeficiency

Lin Wang
Aiyan Ren
Yuanyuan He
Lu Wang
Sixi Wang
Xin Xie
Mei Tan
Yan Chen
Pei Huang
Zuochen Du

Frontiers in Genetics

doi 10.3389/fgene.2025.1641956

3,249 views

Review

Published on 06 Oct 2025

Harnessing multi-omics approaches to combat Karnal bunt of wheat: a review of advances and future prospects

Renu Sharma
Satish Kumar
C. N Mishra
O. P. Ahlawat
Ratan Tiwari

Frontiers in Genetics

doi 10.3389/fgene.2025.1687301

2,372 views

Policy and Practice Reviews

Published on 03 Oct 2025

A training program to extend the reach of the deciphering developmental disorders in Africa (DDD-Africa) study

Aaliah Charles
Zané Lombard
Nadia Carstens
Zandisiwe Goliath
Aimé Lumaka
Prince Makay
Nadja Louw
Robyn Kerr
Daniesha Govender
Amanda Krause

Frontiers in Genetics

doi 10.3389/fgene.2025.1611047

2,899 views

Review

Published on 03 Oct 2025

The roles of serine protease inhibitors in dermatoses

Zhenzhen Xiao
Yue Kang
Yunqian Zhuo
Rui Li
Yingjian Tan

Frontiers in Genetics

doi 10.3389/fgene.2025.1624512

3,777 views

Original Research

Published on 03 Oct 2025

HFTC: a hierarchical fungal taxonomic classification model for ITS sequences using low-dimensional embedding features

Jiawei Wang
Shaojie Qiao
Dongsheng Xiang
Yangcheng Liao
Chao Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1650244

1,968 views

Original Research

Published on 03 Oct 2025

Sex-specific gene expression and weighted co-expression network analysis suggest distinct sex-specific molecular signatures in acutely suicidal MDD-patients without somatic comorbidities

Michael Fritz
Karlheinz Holzmann
Silvia Castany
Heidrun Haas
Christian Montag
David Engblom
Judith Streb
Manuela Dudeck

Frontiers in Genetics

doi 10.3389/fgene.2025.1653768

4,081 views
1 citation

Review

Published on 02 Oct 2025

Recent advances of DNA methylation in osteonecrosis of the femoral head

Tingting Zhou
Huan Liu
Huayan Li
Yan Zhang
Xiaoming Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1526852

3,775 views

Original Research

Published on 02 Oct 2025

Time-series transcriptomics and alternative splicing analysis of embryonic development of the asian honeybee (Apis cerana)

Xiang Ding
Zukai Liu
Linsen Ou
Zhihui Wang
Qian Xu
Runlang Su

Frontiers in Genetics

doi 10.3389/fgene.2025.1665548

2,526 views

963 Publications

volumes

Case Report: Practical approach to differentiating juvenile parkinsonism of genetic cause and drug-induced parkinsonism in adolescents: a case series and literature review

Editorial: Application of next-generation sequencing in clinical settings

The molecular characterization of seven novel GLI family zinc finger 3 (GLI3) variants in Chinese families with limb malformations

Integrated transcriptomic and single-cell RNA sequencing identifies lysosomal ion channel genes as potential biomarkers for Alzheimer’s disease

GTAT-GRN: a graph topology-aware attention method with multi-source feature fusion for gene regulatory network inference

Catalogue of mitotic chromosome-associated small RNAs in mouse 3T3 cell line

Ethical, legal, and policy dimensions and contentions for reanalysis and reinterpretation of clinical genetic testing results

Epigenetic and metabolic reprogramming via nanotechnology: a synergistic approach to cancer vaccination in lung tumors

NanoMarine therapeutics: a new wave in drug delivery from oceanic bioresources targeting colon cancer via miRNA modulation

Editorial: Genetics and justice: the implications of large-scale genome sequencing initiatives in the global south

Modulation of the lncRNA TCONS_00265853-miR-421-5p-CLOCK axis by Ziyin Buyang Formula in polycystic ovarian syndrome with circadian rhythm disruption: an integrated bioinformatics and experimental approach

A novel splicing variant in NBAS identified by minigene assay causes infantile liver failure syndrome type 2

Pain - related methylation driver genes affect the prognosis of pancreatic cancer patients by altering immune function and perineural infiltration

Correction: FEZF1-AS1 drives autophagy-mediated progression of colon cancer and reduces chemosensitivity through inhabiting the PI3K/AKT/mTOR signaling pathway

Identification of shared diagnostic genes between osteoporosis and Crohn’s disease through integrated transcriptomic analysis and machine learning

Correction: Multi-omics integration uncovers key transcriptional regulators in triple-negative breast cancer spatial heterogeneity

A novel de novo IL2RG nonsense mutation in a pediatric patient with X-linked severe combined immunodeficiency

Harnessing multi-omics approaches to combat Karnal bunt of wheat: a review of advances and future prospects

A training program to extend the reach of the deciphering developmental disorders in Africa (DDD-Africa) study

The roles of serine protease inhibitors in dermatoses

HFTC: a hierarchical fungal taxonomic classification model for ITS sequences using low-dimensional embedding features

Sex-specific gene expression and weighted co-expression network analysis suggest distinct sex-specific molecular signatures in acutely suicidal MDD-patients without somatic comorbidities

Recent advances of DNA methylation in osteonecrosis of the femoral head

Time-series transcriptomics and alternative splicing analysis of embryonic development of the asian honeybee (Apis cerana)