Frontiers in Genetics

Brief Research Report

Published on 08 Oct 2025

A novel splicing variant in NBAS identified by minigene assay causes infantile liver failure syndrome type 2

Anna Hu
Jun Liang
Hongbo Liu
Jinghui Jiang
Fujing Xie
Xin Zhou
Xiaojia Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1687266

1,765 views

Original Research

Published on 08 Oct 2025

Modulation of the lncRNA TCONS_00265853-miR-421-5p-CLOCK axis by Ziyin Buyang Formula in polycystic ovarian syndrome with circadian rhythm disruption: an integrated bioinformatics and experimental approach

Haixia Huang
Ling Sun
Fan Jia
Yong Tan
Yahong Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1658812

2,268 views

Review

Published on 08 Oct 2025

NanoMarine therapeutics: a new wave in drug delivery from oceanic bioresources targeting colon cancer via miRNA modulation

Ramkumar Muthu
Rajkumar Manickam
Rajkumar Thamarai
Sivabalan Sivasamy
Karthikeyan Mahendran
Rajkumar Prabhakaran

Frontiers in Genetics

doi 10.3389/fgene.2025.1668618

4,189 views
1 citation

Original Research

Published on 08 Oct 2025

Pain - related methylation driver genes affect the prognosis of pancreatic cancer patients by altering immune function and perineural infiltration

Chencheng Zhang
Weiwei Xu
Xudong Chen
Xingdan Wang
Xiaopeng Cui
Wenjing Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1600883

2,687 views

Editorial

Published on 08 Oct 2025

Editorial: Genetics and justice: the implications of large-scale genome sequencing initiatives in the global south

Michel Satya Naslavsky
Tayyaba Jiwani
Ernesto Schwartz-Marin

Frontiers in Genetics

doi 10.3389/fgene.2025.1703507

1,779 views

Correction

Published on 07 Oct 2025

Correction: FEZF1-AS1 drives autophagy-mediated progression of colon cancer and reduces chemosensitivity through inhabiting the PI3K/AKT/mTOR signaling pathway

Xiaoping Yang
Zuohui Yuan
Lingzhu Gou
Long Cheng
Zirui Wang
Pingfan Wu
Xiaochun Wang
Xueni Ma
Tiantian Ma
Yi Yu

Frontiers in Genetics

doi 10.3389/fgene.2025.1684479

1,400 views

Original Research

Published on 07 Oct 2025

Identification of shared diagnostic genes between osteoporosis and Crohn’s disease through integrated transcriptomic analysis and machine learning

Guirong Yi
Peng Zhou
Qinxu Yang
Maosheng Zhao
Qiaoqiao Yang
Shensong Li
Chenpo Dang

Frontiers in Genetics

doi 10.3389/fgene.2025.1609915

2,577 views

Original Research

Published on 07 Oct 2025

A novel de novo IL2RG nonsense mutation in a pediatric patient with X-linked severe combined immunodeficiency

Lin Wang
Aiyan Ren
Yuanyuan He
Lu Wang
Sixi Wang
Xin Xie
Mei Tan
Yan Chen
Pei Huang
Zuochen Du

Frontiers in Genetics

doi 10.3389/fgene.2025.1641956

3,480 views
1 citation

Correction

Published on 07 Oct 2025

Correction: Multi-omics integration uncovers key transcriptional regulators in triple-negative breast cancer spatial heterogeneity

Ning Zhang
Ye Zhang
Rui-Fei Yang
Min Tan
Hai-Qing Chu
Abdur Rehman
Lu-Yu Yang
Ya-Yu Li
Fahad M. Alshabrmi
Xin Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1701926

1,346 views

Review

Published on 06 Oct 2025

Harnessing multi-omics approaches to combat Karnal bunt of wheat: a review of advances and future prospects

Renu Sharma
Satish Kumar
C. N Mishra
O. P. Ahlawat
Ratan Tiwari

Frontiers in Genetics

doi 10.3389/fgene.2025.1687301

2,659 views

Policy and Practice Reviews

Published on 03 Oct 2025

A training program to extend the reach of the deciphering developmental disorders in Africa (DDD-Africa) study

Aaliah Charles
Zané Lombard
Nadia Carstens
Zandisiwe Goliath
Aimé Lumaka
Prince Makay
Nadja Louw
Robyn Kerr
Daniesha Govender
Amanda Krause

Frontiers in Genetics

doi 10.3389/fgene.2025.1611047

3,222 views

Review

Published on 03 Oct 2025

The roles of serine protease inhibitors in dermatoses

Zhenzhen Xiao
Yue Kang
Yunqian Zhuo
Rui Li
Yingjian Tan

Frontiers in Genetics

doi 10.3389/fgene.2025.1624512

4,239 views

Original Research

Published on 03 Oct 2025

HFTC: a hierarchical fungal taxonomic classification model for ITS sequences using low-dimensional embedding features

Jiawei Wang
Shaojie Qiao
Dongsheng Xiang
Yangcheng Liao
Chao Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1650244

2,331 views

Original Research

Published on 03 Oct 2025

Sex-specific gene expression and weighted co-expression network analysis suggest distinct sex-specific molecular signatures in acutely suicidal MDD-patients without somatic comorbidities

Michael Fritz
Karlheinz Holzmann
Silvia Castany
Heidrun Haas
Christian Montag
David Engblom
Judith Streb
Manuela Dudeck

Frontiers in Genetics

doi 10.3389/fgene.2025.1653768

4,406 views
1 citation

Review

Published on 02 Oct 2025

Recent advances of DNA methylation in osteonecrosis of the femoral head

Tingting Zhou
Huan Liu
Huayan Li
Yan Zhang
Xiaoming Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1526852

4,081 views

Original Research

Published on 02 Oct 2025

Analyses of haplotypes of TLR2 and TLR3 genes for COVID-19 prognosis in a cohort of professionals who worked in the first pandemic wave in Belém-PA, Brazil

Marcos Jessé Abrahão Silva
Luiza Raquel Tapajós Figueira
Daniele Melo Sardinha
Eliete Costa da Cruz
Natasha Cristina Oliveira Andrade
Sebastião Kauã De Sousa Bispo
Thiago Augusto Ferreira Dos Anjos
Everaldina Cordeiro Dos Santos
Ana Judith Pires Garcia
Luana Nepomuceno Gondim Costa Lima

Frontiers in Genetics

doi 10.3389/fgene.2025.1659269

1,572 views
1 citation

Original Research

Published on 02 Oct 2025

Time-series transcriptomics and alternative splicing analysis of embryonic development of the asian honeybee (Apis cerana)

Xiang Ding
Zukai Liu
Linsen Ou
Zhihui Wang
Qian Xu
Runlang Su

Frontiers in Genetics

doi 10.3389/fgene.2025.1665548

2,774 views

Mini Review

Published on 01 Oct 2025

Recent progress on DNA methylation in psoriasis

Zhaoping Lin
Xiaoting Wu
Xuqin Hong
Dongying Luo
Hui Li
Fei Ma
Cong Huang
Bo Yu
Jing Gao
Changbing Shen

Frontiers in Genetics

doi 10.3389/fgene.2025.1681666

3,951 views

Original Research

Published on 01 Oct 2025

Comparative analysis of miRNA expression in Yili horses pre- and post-5000-m race

Shikun Ma
Wanlu Ren
Zexu Li
Luling Li
Ran Wang
Yi Su
Qiuping Huang
Shan Dehaxi
Jianwen Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1676558

3,046 views
2 citations

Original Research

Published on 01 Oct 2025

Identification and validation of calcium signaling pathway-related biomarkers in T1 and T2 lymph node metastatic gastric cancer

Mingzhi Cai
Xinyang Nie
Fenglin Cai
Xiuding Yang
Weilin Sun
Rupeng Zhang
Han Liang
Yonglin Yang
Li Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1653700

2,597 views
1 citation

Original Research

Published on 01 Oct 2025

Comprehensive genetic diversity revealed in the pre-breeding RILs (O. sativa × O. rufipogon) with enhanced yield and pigmented grain quality

Subhas Chandra Roy
Pankaj Shil

Frontiers in Genetics

doi 10.3389/fgene.2025.1659937

3,014 views

Data Report

Published on 01 Oct 2025

Annotated genome of Aedes japonicus japonicus using a hybrid-assembly approach

Friederike Reuss
Tilman Schell
Haruhiko Isawa
Shinji Kasai
Sven Klimpel
Ruth Müller
Markus Pfenninger
Judith Kochmann

Frontiers in Genetics

doi 10.3389/fgene.2025.1667262

2,605 views

Original Research

Published on 01 Oct 2025

Using buccal methylomic data to create explainable aging clocks as well as classifiers and regressors for lifestyle and demographic factors

Maxim N. Shokhirev
Adiv A. Johnson

Frontiers in Genetics

doi 10.3389/fgene.2025.1637186

4,404 views

Editorial

Published on 30 Sep 2025

Editorial: Genetic dissection and improvement of crop quality and stress adaptation

Liwei Zheng
Hangkai Zhang
Songwen Zhang
Yingpeng Hua
Lihu Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1694599

2,850 views

16,551 Publications

volumes

Volume 16 - 2025

A novel splicing variant in NBAS identified by minigene assay causes infantile liver failure syndrome type 2

Modulation of the lncRNA TCONS_00265853-miR-421-5p-CLOCK axis by Ziyin Buyang Formula in polycystic ovarian syndrome with circadian rhythm disruption: an integrated bioinformatics and experimental approach

NanoMarine therapeutics: a new wave in drug delivery from oceanic bioresources targeting colon cancer via miRNA modulation

Pain - related methylation driver genes affect the prognosis of pancreatic cancer patients by altering immune function and perineural infiltration

Editorial: Genetics and justice: the implications of large-scale genome sequencing initiatives in the global south

Correction: FEZF1-AS1 drives autophagy-mediated progression of colon cancer and reduces chemosensitivity through inhabiting the PI3K/AKT/mTOR signaling pathway

Identification of shared diagnostic genes between osteoporosis and Crohn’s disease through integrated transcriptomic analysis and machine learning

A novel de novo IL2RG nonsense mutation in a pediatric patient with X-linked severe combined immunodeficiency

Correction: Multi-omics integration uncovers key transcriptional regulators in triple-negative breast cancer spatial heterogeneity

Harnessing multi-omics approaches to combat Karnal bunt of wheat: a review of advances and future prospects

A training program to extend the reach of the deciphering developmental disorders in Africa (DDD-Africa) study

The roles of serine protease inhibitors in dermatoses

HFTC: a hierarchical fungal taxonomic classification model for ITS sequences using low-dimensional embedding features

Sex-specific gene expression and weighted co-expression network analysis suggest distinct sex-specific molecular signatures in acutely suicidal MDD-patients without somatic comorbidities

Recent advances of DNA methylation in osteonecrosis of the femoral head

Analyses of haplotypes of TLR2 and TLR3 genes for COVID-19 prognosis in a cohort of professionals who worked in the first pandemic wave in Belém-PA, Brazil

Time-series transcriptomics and alternative splicing analysis of embryonic development of the asian honeybee (Apis cerana)

Recent progress on DNA methylation in psoriasis

Comparative analysis of miRNA expression in Yili horses pre- and post-5000-m race

Identification and validation of calcium signaling pathway-related biomarkers in T1 and T2 lymph node metastatic gastric cancer

Comprehensive genetic diversity revealed in the pre-breeding RILs (O. sativa × O. rufipogon) with enhanced yield and pigmented grain quality

Annotated genome of Aedes japonicus japonicus using a hybrid-assembly approach

Using buccal methylomic data to create explainable aging clocks as well as classifiers and regressors for lifestyle and demographic factors

Editorial: Genetic dissection and improvement of crop quality and stress adaptation