Frontiers in Genetics

Original Research

Published on 05 Sep 2025

Assembly factor for spindle microtubules (ASPM) promotes osimertinib resistance in lung cancer by increasing EGFR stability

Pengpeng Gui
Zhengyi Han
Zhenyu Yin
Peng Cao
Xin Zhou
Yan Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1593314

2,684 views

Original Research

Published on 05 Sep 2025

Temporal regulation of genetic programs governing multiple cell death during myocardial ischemia-reperfusion injury

Qiuyu Pang
Xiangmin Meng
Zhenfang Zhou
Lu You
Jinghan Yuan
Qipu Feng
Bingmei Zhu

Frontiers in Genetics

doi 10.3389/fgene.2025.1632867

2,302 views
1 citation

Original Research

Published on 03 Sep 2025

3D-cultured hADSCs-derived exosomes deliver circ_0011129 to synergistically attenuate skin photoaging

Yu Zhang
Feng Zhou
Gang Nie
Liang Li
Juan Wen
Shimin He
Amin Yao

Frontiers in Genetics

doi 10.3389/fgene.2025.1627472

3,353 views

Original Research

Published on 03 Sep 2025

Integrating BERT pre-training with graph common neighbours for predicting ceRNA interactions

Zhengxing Xie
Tianping Ying
Ge Jing
Shiyang Liang
Junhua Liu
Lianghua Tang

Frontiers in Genetics

doi 10.3389/fgene.2025.1606016

1,673 views

Original Research

Published on 03 Sep 2025

Validation of a genome-wide polygenic score for body mass index in South Asians

Ramesh Menon
Nikhat Khan
Sandeep Charugulla
Akshi Bassi
Pooja Dangare
Akshay Dedaniya
Aakanksha Pant
Rammurthy Anjanappa
Praveena L. Samson
Uthra Satagopan

Frontiers in Genetics

doi 10.3389/fgene.2025.1603542

2,062 views

Perspective

Published on 03 Sep 2025

From reading to writing genomes: a new direction in ELSI

Koichi Mikami

Frontiers in Genetics

doi 10.3389/fgene.2025.1667769

2,893 views

Original Research

Published on 03 Sep 2025

Multi-omics integration uncovers key transcriptional regulators in triple-negative breast cancer spatial heterogeneity

Ning Zhang
Ye Zhang
Rui-Fei Yang
Min Tan
Hai-Qing Chu
Abdur Rehman
Lu-Yu Yang
Ya-Yu Li
Fahad M. Alshabrmi
Xin Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1614254

3,760 views
1 citation

Data Report

Published on 01 Sep 2025

Data report: transcriptome profiling of 13 tissues of Junmu No. 1 boars

Chunyan Bai
Jiayi Ning
Junwen Fei
Zhenbo Wang
Yu He
Jing Li
Xiaoran Zhang
Shuang Liang
Dali Wang
Hao Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1641395

2,223 views

Original Research

Published on 01 Sep 2025

A de novo mutation in RAB11A is associated with neurodevelopmental disorder accompanied by variable multisystem abnormalities

Huiting Zhang
Jingtao Zhang
Xue Ma
Zhehui Chen
Ying Jin
Mengqiu Li
Hui Dong
Feng Gu
Yao Zhang
Yanling Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1636206

1,913 views

Original Research

Published on 01 Sep 2025

Mining for gene-environment and gene-gene interactions: parametric and non-parametric tests for detecting variance quantitative trait loci

Wan-Yu Lin

Frontiers in Genetics

doi 10.3389/fgene.2025.1617504

2,613 views

Editorial

Published on 01 Sep 2025

Editorial: Mitochondria in metabolic reprogramming and immune activation: the key gene and therapeutic target

Yongzheng Guo

Frontiers in Genetics

doi 10.3389/fgene.2025.1686852

2,714 views

Original Research

Published on 29 Aug 2025

Comparative analysis of blood whole transcriptome profiles in Yili horses pre- and post-5000-meter racing

Yi Su
Wanlu Ren
Shikun Ma
Jun Meng
Xinkui Yao
Yaqi Zeng
Zexu Li
Luling Li
Ran Wang
Jianwen Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1651628

4,013 views
1 citation

Brief Research Report

Published on 29 Aug 2025

Identification of oncofetal PIWI-interacting RNAs as potential prognostic biomarkers in non-small cell lung cancer

Michelle E. Pewarchuk
Vanessa G. P. Souza
David E. Cohn
Nikita Telkar
Greg L. Stewart
Katya H. Bénard
Patricia P. Reis
Victor D. Martinez
Wendy P. Robinson
Wan L. Lam

Frontiers in Genetics

doi 10.3389/fgene.2025.1611805

1,890 views

Original Research

Published on 29 Aug 2025

Identification and experimental validation of circular RNA-associated ceRNA networks in intrauterine adhesion

Yajie Chang
Rui Xiang
Qi Guo
Jing Li
Xiaolan Li
Zhi Zeng
Jintao Peng
Xiaoyan Liang

Frontiers in Genetics

doi 10.3389/fgene.2025.1619698

2,034 views

Original Research

Published on 29 Aug 2025

Affective phenotypes in heterozygous LRRK2 R1441G knock-in mice

Marcus H. F. Ng
Jimmy W. Y. Lam
Zoe Y. K. Choi
Hui-Fang Liu
Philip W. L. Ho
Benson W. M. Lau
Benjamin K. Yee

Frontiers in Genetics

doi 10.3389/fgene.2025.1629897

3,632 views

Mini Review

Published on 29 Aug 2025

Mesenchymal stem cells and exosomes in ischemic brain injury: a review

Haiyan Xu
Lanlan Yang
Weitie Wang
Chengwei Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1639756

3,784 views

Original Research

Published on 29 Aug 2025

Targeted exome sequencing for molecular diagnosis of pediatric Alport syndrome in Southwest China

Cong Zhou
Yuanyuan Xiao
Xing Wei
Jing Wang
Shanling Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1580864

1,620 views

Original Research

Published on 29 Aug 2025

The first complete mitochondrial genome of Biotodoma cupido (Cichiliformes: Cichlidae) and its phylogeny

Xiaoli Zhang
Shuang-Xi Jia
Cheng-He Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1623517

2,381 views
1 citation

Correction

Published on 29 Aug 2025

Correction: Engineering novel features for diabetes complication prediction using synthetic electronic health records

Daniel Voskergian
Burcu Bakir-Gungor
Malik Yousef

Frontiers in Genetics

doi 10.3389/fgene.2025.1687832

1,097 views

Brief Research Report

Published on 29 Aug 2025

Codon usage bias analysis of the WRKY gene family in Musa acuminata

Jiaman Sun
Ji Zhang
Jinzhong Zhang
Brett J. Ferguson
Andrew Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1647037

2,213 views

Original Research

Published on 28 Aug 2025

Identification and validation of a histone modification-related gene signature to predict the prognosis of multiple myeloma

Juan Lyu
Shanmei Lyu
Ying Qian
Yi Feng
Zhuan Zheng
Lihong Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1613631

2,039 views

Editorial

Published on 28 Aug 2025

Editorial: Emerging relevance of molecular profiling in global cancer research and management

Premila Leiphrakpam
Srijan Shukla
Chandrakanth Are

Frontiers in Genetics

doi 10.3389/fgene.2025.1679501

1,565 views

Original Research

Published on 26 Aug 2025

Novel estrogen-related gene variants identified by whole-exome sequencing in pregnancy-associated intrahepatic cholestasis

Hua Lai
Siming Xin
Jinliang Zhang
Yang Hu
Wenjuan Fan
Hong Wan
Bowen Chen
Yang Zou
Xiaoming Zeng
Xianxian Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1626890

2,550 views

Original Research

Published on 26 Aug 2025

Compound heterozygous missense and intronic variants in B9D1 contribute to a recurrent Meckel syndrome pedigree

Huining Jing
Bocheng Xu
Hao Wang
Shanling Liu
He Wang
Jingqun Mai
Wencong Yao
Zhu Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1663455

2,549 views

963 Publications

volumes

Assembly factor for spindle microtubules (ASPM) promotes osimertinib resistance in lung cancer by increasing EGFR stability

Temporal regulation of genetic programs governing multiple cell death during myocardial ischemia-reperfusion injury

3D-cultured hADSCs-derived exosomes deliver circ_0011129 to synergistically attenuate skin photoaging

Integrating BERT pre-training with graph common neighbours for predicting ceRNA interactions

Validation of a genome-wide polygenic score for body mass index in South Asians

From reading to writing genomes: a new direction in ELSI

Multi-omics integration uncovers key transcriptional regulators in triple-negative breast cancer spatial heterogeneity

Data report: transcriptome profiling of 13 tissues of Junmu No. 1 boars

A de novo mutation in RAB11A is associated with neurodevelopmental disorder accompanied by variable multisystem abnormalities

Mining for gene-environment and gene-gene interactions: parametric and non-parametric tests for detecting variance quantitative trait loci

Editorial: Mitochondria in metabolic reprogramming and immune activation: the key gene and therapeutic target

Comparative analysis of blood whole transcriptome profiles in Yili horses pre- and post-5000-meter racing

Identification of oncofetal PIWI-interacting RNAs as potential prognostic biomarkers in non-small cell lung cancer

Identification and experimental validation of circular RNA-associated ceRNA networks in intrauterine adhesion

Affective phenotypes in heterozygous LRRK2 R1441G knock-in mice

Mesenchymal stem cells and exosomes in ischemic brain injury: a review

Targeted exome sequencing for molecular diagnosis of pediatric Alport syndrome in Southwest China

The first complete mitochondrial genome of Biotodoma cupido (Cichiliformes: Cichlidae) and its phylogeny

Correction: Engineering novel features for diabetes complication prediction using synthetic electronic health records

Codon usage bias analysis of the WRKY gene family in Musa acuminata

Identification and validation of a histone modification-related gene signature to predict the prognosis of multiple myeloma

Editorial: Emerging relevance of molecular profiling in global cancer research and management

Novel estrogen-related gene variants identified by whole-exome sequencing in pregnancy-associated intrahepatic cholestasis

Compound heterozygous missense and intronic variants in B9D1 contribute to a recurrent Meckel syndrome pedigree