Frontiers in Genetics

Case Report

Published on 12 Nov 2025

Case Report: Compound heterozygous CEP152 c.3346-5T>C variant and chr15 deletion causing recurrent MCPH–SCKS in a Chinese pregnant woman across two consecutive pregnancies

Tao Zhang
Hua Yuan
Xiaoliang Shi
Yao He
Haitao Pan
Yongxing Zhong
Jintang Zhang
Zhen Yang
Yunyan Ke
Yan Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1646297

493 views

Original Research

Published on 12 Nov 2025

Computational-experimental strategy identifies Co-upregulated biomarkers linking coronary heart disease and type 2 diabetes pathogenesis

Wei Li
Yu Cao
Chen Yu
Bingjun Che
Miao He
Dongbiao Li
Lihong Jiang
Lijing Ma

Frontiers in Genetics

doi 10.3389/fgene.2025.1673303

361 views

Original Research

Accepted on 11 Nov 2025

Five Novel EP300 Variants Expand the Genetic and Phenotypic Spectrum of Rubinstein–Taybi Syndrome Type 2 in Chinese Patients

Qiang Zhang
Qi Yang
Xunzhao Zhou
Zailong Qin
Jingsi Luo

Frontiers in Genetics

Original Research

Accepted on 11 Nov 2025

Development of a senescence-related lncRNA signature in endometrial cancer based on multiple machine learning models

Jie Lin
Xuemei Lei
Yanhong Li
Xin Jiang
Feng Le Jiang
Aihua Guo
Xintong Cai
Xingming Ye
Yang Sun

Frontiers in Genetics

147 views

Original Research

Accepted on 11 Nov 2025

SHMT2 modulates the transcriptome and metabolism profiles to promote the tumor phenotypes of bladder cancer HT-1376 cells

Xiaobo Guo
Gang Li

Frontiers in Genetics

105 views

Review

Published on 11 Nov 2025

Ocular surface health and disease: insight from single-cell RNA sequencing

Shangkun Ou
Minqing Cai
Yuchong Feng
Sijie Lin
Xueer Zheng
Su Zhao
Hao Gu
Yiming Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1683167

488 views

Mini Review

Published on 11 Nov 2025

Epigenetic landscape in lysosomal storage disorders: mechanisms and modulation

Andrés Felipe Leal
Harry Pachajoa
Shunji Tomatsu

Frontiers in Genetics

doi 10.3389/fgene.2025.1679497

658 views

Original Research

Published on 11 Nov 2025

Germline activating sequence variations in RASopathy spectrum genes: genotype–phenotype correlation in a North Indian cohort

Shifali Gupta
Priyanka Srivastava
Roshan Daniel
Chitra Bhardwaj
Parminder Kaur
Pratibha Bawa
Anu Kumari
Ravi Pratap Singh Bhadoriya
Mrinali Peters
Anupriya Kaur

Frontiers in Genetics

doi 10.3389/fgene.2025.1677143

815 views

Original Research

Accepted on 10 Nov 2025

Development of a Prognostic Model Related to Mitochondria and programmed cell death related genes in Bladder Cancer

Xuwei Zhao
Hongyao Liu
Chao Wang
Fuyu Guo
Bin Yang

Frontiers in Genetics

Review

Accepted on 10 Nov 2025

Circular RNAs at the Crossroads of Acute Pancreatitis: Bridging Molecular Mechanisms to Diagnostic and Therapeutic Innovations

JING CHEN
Xiaoling Chen
Fei He

Frontiers in Genetics

Original Research

Accepted on 10 Nov 2025

Potential diagnostic markers and therapeutic targets for obstructive sleep apnea with comorbid depression based on bioinformatics analysis

Xiao Guo
Yinfei Lu
Zao Tang
Xiang yu Zhou
Wanting Lin

Frontiers in Genetics

Original Research

Accepted on 10 Nov 2025

Transcriptome-wide m6A landscape across diverse porcine tissues revealed by Nanopore direct RNA sequencing

Yuyun Xing
Qiang Yang
Yaya Liao
Zifeng Ding
Xiaoyun Chen
Chao Yin
Bin Yang

Frontiers in Genetics

Review

Accepted on 10 Nov 2025

Biogenesis and Function of Circular RNAs and Their Implications in the Down Syndrome Brain

Shahidee Zainal Abidin
Nurul Nadirah Razali
Pike See Cheah
King-Hwa Ling

Frontiers in Genetics

Original Research

Published on 10 Nov 2025

Genotyping strategies for single-step genomic predictions in a simulated sheep population under different scenarios of pedigree error types

Artur O. Rocha
Leonardo S. Gloria
Andre C. Araujo
Hui Wen
Carrie S. Wilson
Bradley A. Freking
Thomas W. Murphy
Joan M. Burke
Ronald M. Lewis
Luiz F. Brito

Frontiers in Genetics

doi 10.3389/fgene.2025.1697103

793 views

Original Research

Published on 10 Nov 2025

Unveiling disulfidptosis-linked lncRNA signatures: insights into the immune microenvironment and drug responsiveness in oral squamous cell carcinoma

Xue Meng
Lichao Cao
Yantao Liu
Sihan Wang
Weixian Liu
Guangping Zhang
Siqi Guo
Fangyu Qi
Tingting Wang
Yuhe Xia

Frontiers in Genetics

doi 10.3389/fgene.2025.1650544

480 views

Original Research

Published on 10 Nov 2025

Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) leaves

Ting Yang
Xiaolu Lin
Rui Chen
Ruiqi Wang
Tong Li
Fulong Shen
Xiaowei Zhang
Lianghua Lai
Bing Lu
Jiliang Wei

Frontiers in Genetics

doi 10.3389/fgene.2025.1662815

553 views

16,364 Publications

Volume 16 - 2025

Case Report: Compound heterozygous CEP152 c.3346-5T>C variant and chr15 deletion causing recurrent MCPH–SCKS in a Chinese pregnant woman across two consecutive pregnancies

Computational-experimental strategy identifies Co-upregulated biomarkers linking coronary heart disease and type 2 diabetes pathogenesis

Five Novel EP300 Variants Expand the Genetic and Phenotypic Spectrum of Rubinstein–Taybi Syndrome Type 2 in Chinese Patients

Development of a senescence-related lncRNA signature in endometrial cancer based on multiple machine learning models

SHMT2 modulates the transcriptome and metabolism profiles to promote the tumor phenotypes of bladder cancer HT-1376 cells

Ocular surface health and disease: insight from single-cell RNA sequencing

Epigenetic landscape in lysosomal storage disorders: mechanisms and modulation

Germline activating sequence variations in RASopathy spectrum genes: genotype–phenotype correlation in a North Indian cohort

Development of a Prognostic Model Related to Mitochondria and programmed cell death related genes in Bladder Cancer

Circular RNAs at the Crossroads of Acute Pancreatitis: Bridging Molecular Mechanisms to Diagnostic and Therapeutic Innovations

Potential diagnostic markers and therapeutic targets for obstructive sleep apnea with comorbid depression based on bioinformatics analysis

Transcriptome-wide m6A landscape across diverse porcine tissues revealed by Nanopore direct RNA sequencing

Biogenesis and Function of Circular RNAs and Their Implications in the Down Syndrome Brain

Genotyping strategies for single-step genomic predictions in a simulated sheep population under different scenarios of pedigree error types

Unveiling disulfidptosis-linked lncRNA signatures: insights into the immune microenvironment and drug responsiveness in oral squamous cell carcinoma

Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) leaves