Frontiers in Genetics

Original Research

Published on 24 Jul 2025

A bioinformatics analysis of the correlation between hepatic ischemia–reperfusion injury and postoperative cognitive dysfunction

Qing Hu
Haijie Liu
Yunfei Bao
Zhihao Feng
Hongbo Zhang
Jianling Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1607446

2,045 views

Original Research

Published on 24 Jul 2025

FEZF1-AS1 drives autophagy-mediated progression of colon cancer and reduces chemosensitivity through inhabiting the PI3K/AKT/mTOR signaling pathway

Xiaoping Yang
Zuohui Yuan
Lingzhu Gou
Long Cheng
Zirui Wang
Pingfan Wu
Xiaochun Wang
Xueni Ma
Tiantian Ma
Yi Yu

Frontiers in Genetics

doi 10.3389/fgene.2025.1514205

2,215 views

Original Research

Published on 23 Jul 2025

Genetic association between STAT4 and primary Sjögren’s syndrome in Han Chinese women

Fangfang Li
Junhui Lu
Chao Cen
Wanqiu Zhen
Jiaojiao Zhang
Shengming Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1628428

3,802 views

Original Research

Published on 23 Jul 2025

EPI-DynFusion: enhancer-promoter interaction prediction model based on sequence features and dynamic fusion mechanisms

Ao Zhang
Jianhua Jia
Mingwei Sun
Xin Wei

Frontiers in Genetics

doi 10.3389/fgene.2025.1614222

2,207 views

Original Research

Published on 23 Jul 2025

Genetic prediction of the casual relationship between micronutrients and ER+ breast cancer: a Mendelian randomized study

Wei-Da Fu
Jin-Qiu Wang
Jin Luo
Ming-Ze Wei
Yong-Ping Dai
He-He Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1599724

2,951 views

Original Research

Published on 23 Jul 2025

Identification of key genes associated with infertile endometriosis based on bioinformatic analysis

Linlin Chang
Hongjuan Ye
Min Hou
Xin Xie
Yang Wang
Jie Cheng
Rongxiang Wang
Xiaocong Chen
Xinxin Quan
Lihua Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1615268

3,787 views

Perspective

Published on 23 Jul 2025

The peruvian genome project: expanding the global pool of genome diversity from South America

Heinner Guio
Cesar Sanchez
Victor Borda
Luis Jaramillo-Valverde
Omar Caceres
Carlos Padilla
Omar Trujillo
Julio A. Poterico
Carolina Silva-Carvalho
Mary Horton

Frontiers in Genetics

doi 10.3389/fgene.2025.1614021

5,939 views
2 citations

Methods

Published on 23 Jul 2025

A likelihood ratio framework for inferring close kinship from dynamically selected SNPs

Jianye Ge
Bruce Budowle
Michael Cariaso
Kristen Mittelman
David Mittelman

Frontiers in Genetics

doi 10.3389/fgene.2025.1635734

2,814 views
1 citation

Original Research

Published on 23 Jul 2025

The chloroplast genome of the Peltigera elisabethae photobiont Chloroidium sp. W5 and its phylogenetic implications

Guldiyar Adil
Shenglei Liu
Xiaoyan Bao
Reyim Mamut

Frontiers in Genetics

doi 10.3389/fgene.2025.1602048

1,860 views
1 citation

Original Research

Published on 22 Jul 2025

Development and validation of a machine-learning-based model for identification of genes associated with sepsis-associated acute kidney injury

Chen Lin
Meng Zheng
Wensi Wu
Zhishan Wang
Guofeng Lu
Shaodan Feng
Xinlan Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1561331

3,203 views

Original Research

Published on 21 Jul 2025

Estimation of breed composition of South African sheep affected with wet carcass syndrome

Bhaveni B. Kooverjee
Magrieta A. Van Der Nest
Michael D. MacNeil
Michiel M. Scholtz
Frederick W. C. Neser
Pranisha Soma

Frontiers in Genetics

doi 10.3389/fgene.2025.1635947

2,020 views

Case Report

Published on 21 Jul 2025

Case Report: Pediatric CNS-isolated hemophagocytic lymphohistiocytosis secondary to uniparental disomy of PRF1 mutation

Jiao Xue
Zhenfeng Song
Hongshan Zhao
Chengqing Yang
Fei Li
Zhi Yi
Kaixuan Liu
Ying Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1528844

1,800 views

Case Report

Published on 21 Jul 2025

Ultrasound combined with molecular genetics to diagnose hereditary Renpenning syndrome in early pregnancy: a case report

Yongmei Shen
Lei Zhang
Yaqi Li
Liying Yao
Jiasong Cao
Qimei Lin
Maolin Nie
Hefei Wang
Rongxin Wei
Ying Chang

Frontiers in Genetics

doi 10.3389/fgene.2025.1575378

2,258 views

Original Research

Published on 18 Jul 2025

Preliminary investigation of the effect of ferulic acid on miRNAs and LncRNAs in Mongolian horse skeletal muscle satellite cells

Wendian Gong
Wenqi Ding
Tugeqin Bou
Lin Shi
Yanan Lin
Xiaoyuan Shi
Zheng Li
Huize Wu
Manglai Dugarjaviin
Dongyi Bai

Frontiers in Genetics

doi 10.3389/fgene.2025.1630614

1,692 views

Brief Research Report

Published on 18 Jul 2025

FilaggrinHigh melanomas exhibit active FGFR and allergic signatures with impaired GNA14 and Th1 signatures

Goodwin G. Jinesh
Isha Godwin

Frontiers in Genetics

doi 10.3389/fgene.2025.1569403

2,648 views
1 citation

Original Research

Published on 17 Jul 2025

Incorporating graph representation and mutual attention mechanism for MiRNA-MRNA interaction prediction

Tai-Long Shi
Lei Wang
Leon Wong
Zhu-Hong You
Chang-Qing Yu
Chen Jiang
Si-Zhe Liang

Frontiers in Genetics

doi 10.3389/fgene.2025.1637427

1,985 views
1 citation

Original Research

Published on 17 Jul 2025

Identification of biomarkers between coronary artery disease and non-alcoholic steatohepatitis: a combination of bioinformatics and machine learning

Yihong Lin
Jingmei Song
Xiaohong Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1573621

2,808 views

Case Report

Published on 17 Jul 2025

Case Report: A rare chromosomal imbalance with dup 7q36.3-qter and del 7pter-p22.3 arising from parental pericentric inversion

Rongbo Lin
Wenhui Zhang
Mingwei Huang
Yansheng Shen
Jianxiang Liao
Ping Song
Ying Qi
Jie He
Yuanxiang Xia
Jing Duan

Frontiers in Genetics

doi 10.3389/fgene.2025.1564711

1,938 views

Original Research

Published on 17 Jul 2025

Exploring the prognostic significance and therapeutic potential of SUCLG2 in prostate cancer

Bao Hua
Qing Yang
Shangqing Song
Wenfeng Li
Bin Xu
Yufei Gu

Frontiers in Genetics

doi 10.3389/fgene.2025.1592779

2,500 views
1 citation

Systematic Review

Published on 16 Jul 2025

Association between the PSCA rs2976392 polymorphism and susceptibility to gastric cancer: a meta-analysis

Xiao-Hua Lin
Da-Jun Chen
Li-Juan Wang
Xiu-Ping Wan

Frontiers in Genetics

doi 10.3389/fgene.2025.1618597

2,247 views

Original Research

Published on 16 Jul 2025

Characterization of lactylation modification subtypes and the promoting role of CCL20 in hepatocellular carcinoma progression

Li-Hong Wu
Liu Yang
Xiang-Xu Wang
Shuang Bai
Xi Yan
Jing Wei
Jun Wang
Fei Tian

Frontiers in Genetics

doi 10.3389/fgene.2025.1605055

4,028 views

Original Research

Published on 16 Jul 2025

Evaluation of diverse polygenic risk score models for lung cancer in a small-scale Chinese cohort

Min Gao
Qiwen Zheng
Yue Jiang
Xiao Chang
Xin Zheng

Frontiers in Genetics

doi 10.3389/fgene.2025.1646997

2,848 views
1 citation

Original Research

Published on 16 Jul 2025

Genetic subtypes of type 2 diabetes are distinguished through the lens of abdominal MRI

Elena P. Sorokin
Madeleine Cule
Marjola Thanaj
Nicolas Basty
Brandon Whitcher
Naveed Sattar
E. Louise Thomas
Jimmy D. Bell
Hanieh Yaghootkar

Frontiers in Genetics

doi 10.3389/fgene.2025.1605721

3,999 views
2 citations

Original Research

Published on 16 Jul 2025

Bioinformatics-based analysis of the relationship between STC1 expression and immune infiltration in gastric cancer

Weijun Ma
Xiaoli Ma
Yaoqi Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1499121

3,812 views

963 Publications

volumes

A bioinformatics analysis of the correlation between hepatic ischemia–reperfusion injury and postoperative cognitive dysfunction

FEZF1-AS1 drives autophagy-mediated progression of colon cancer and reduces chemosensitivity through inhabiting the PI3K/AKT/mTOR signaling pathway

Genetic association between STAT4 and primary Sjögren’s syndrome in Han Chinese women

EPI-DynFusion: enhancer-promoter interaction prediction model based on sequence features and dynamic fusion mechanisms

Genetic prediction of the casual relationship between micronutrients and ER+ breast cancer: a Mendelian randomized study

Identification of key genes associated with infertile endometriosis based on bioinformatic analysis

The peruvian genome project: expanding the global pool of genome diversity from South America

A likelihood ratio framework for inferring close kinship from dynamically selected SNPs

The chloroplast genome of the Peltigera elisabethae photobiont Chloroidium sp. W5 and its phylogenetic implications

Development and validation of a machine-learning-based model for identification of genes associated with sepsis-associated acute kidney injury

Estimation of breed composition of South African sheep affected with wet carcass syndrome

Case Report: Pediatric CNS-isolated hemophagocytic lymphohistiocytosis secondary to uniparental disomy of PRF1 mutation

Ultrasound combined with molecular genetics to diagnose hereditary Renpenning syndrome in early pregnancy: a case report

Preliminary investigation of the effect of ferulic acid on miRNAs and LncRNAs in Mongolian horse skeletal muscle satellite cells

FilaggrinHigh melanomas exhibit active FGFR and allergic signatures with impaired GNA14 and Th1 signatures

Incorporating graph representation and mutual attention mechanism for MiRNA-MRNA interaction prediction

Identification of biomarkers between coronary artery disease and non-alcoholic steatohepatitis: a combination of bioinformatics and machine learning

Case Report: A rare chromosomal imbalance with dup 7q36.3-qter and del 7pter-p22.3 arising from parental pericentric inversion

Exploring the prognostic significance and therapeutic potential of SUCLG2 in prostate cancer

Association between the PSCA rs2976392 polymorphism and susceptibility to gastric cancer: a meta-analysis

Characterization of lactylation modification subtypes and the promoting role of CCL20 in hepatocellular carcinoma progression

Evaluation of diverse polygenic risk score models for lung cancer in a small-scale Chinese cohort

Genetic subtypes of type 2 diabetes are distinguished through the lens of abdominal MRI

Bioinformatics-based analysis of the relationship between STC1 expression and immune infiltration in gastric cancer