Frontiers in Genetics

Original Research

Published on 07 Jul 2025

Identification and validation of DNA methylation-driven gene OSR1 as a novel tumor suppressor for the diagnosis and prognosis of breast cancer

Jian Xu
Biao Yang
Ling Cheng
Chen Gan
Runze Huang
Anlong Li
Han Ge
Longyu Hu
Meiwen Ling
Xinyi Zheng

Frontiers in Genetics

doi 10.3389/fgene.2025.1583620

2,843 views

Original Research

Published on 07 Jul 2025

Integrating genome and transcriptome analysis to decipher balanced structural variants in unsolved cases of neurodevelopmental disorders

Simona Mellone
Alice Spano
Denise Vurchio
Giulia Borgonovi
Alessandro Ugonotti
Giulia Paglino
Alba Bianco
Sara Ronzani
Maurizio Sciancalepore
Flavia Prodam

Frontiers in Genetics

doi 10.3389/fgene.2025.1603513

2,250 views

Mini Review

Published on 04 Jul 2025

Application of AI in the identification of gastrointestinal stromal tumors: a comprehensive analysis based on pathological, radiological, and genetic variation features

Lei Zheng
Dan-Wen Jin
Hong-Wei Yu
Ze Yu
Li-Yong Qian

Frontiers in Genetics

doi 10.3389/fgene.2025.1555744

2,801 views
2 citations

Case Report

Published on 04 Jul 2025

Case Report: The window that closed too soon: lessons from a late CLN2 diagnosis and death of a 9-year-old boy

Anna Bryzik
Dawid Larysz
Patrycja Larysz
Julia Izabela Karpierz
Justyna Paprocka

Frontiers in Genetics

doi 10.3389/fgene.2025.1622185

3,566 views

Brief Research Report

Published on 04 Jul 2025

A novel missense variant of HS6ST2 gene in Paganini-Miozzo syndrome with a rare neurodevelopmental and Endocrine phenotypes

Meiling Zhang
Xiao Chang
Xiaoyun Du
Zhen Chen
Xinyue Zhang
Fucheng Cai

Frontiers in Genetics

doi 10.3389/fgene.2025.1515260

1,810 views

Original Research

Published on 04 Jul 2025

The clinical and genetic profiles of spinal muscular atrophy with respiratory distress type 1 and identification of a novel mutation in IGHMBP2 in China

Yanjun Wang
Ya Yang
Jingjing Wang
Qian Han
Nana Zhai
Shufang Xiao

Frontiers in Genetics

doi 10.3389/fgene.2025.1594265

2,001 views

Original Research

Published on 03 Jul 2025

Genome-wide association study and haplotype analyses reveal the genetic architecture of agronomic traits and sugars in sweet sorghum

Abdullah Bin Umar
Ajay Prasanth Ramalingam
Bushra Sadia
Faisal Saeed Awan
Farooq Ahmad Khan
Mariam Nasir
Amy Bernardo
Paul St. Amand
Guihua Bai
P. V. Vara Prasad

Frontiers in Genetics

doi 10.3389/fgene.2025.1611863

3,294 views
1 citation

Case Report

Published on 03 Jul 2025

Case Report: Surgical management of primary lymphedema with a novel PROX1 mutation involving upper and lower limbs

Junzhe Chen
Liangliang Wang
Xiangkui Wu
Bihua Wu
Hai Li
Shune Xiao
Chengliang Deng

Frontiers in Genetics

doi 10.3389/fgene.2025.1560471

2,254 views
3 citations

Brief Research Report

Published on 03 Jul 2025

Statistic tells: the regulatory pendulum of permit trajectories in China’s genetic governance (2021-2024)

Lingqiao Song
Zhenyu Liu
Fanlin Meng

Frontiers in Genetics

doi 10.3389/fgene.2025.1611003

3,189 views

Original Research

Published on 03 Jul 2025

Analysis of microRNA expression reveals convergent evolution of the molecular control of diapause in annual killifishes

Emanuel Barth
Mario Baumgart
Luca Dolfi
Rongfeng Cui
Marco Groth
Roberto Ripa
Aurora Savino
Dario Riccardo Valenzano
Matthias Platzer
Manja Marz

Frontiers in Genetics

doi 10.3389/fgene.2025.1583989

3,155 views
1 citation

Editorial

Published on 03 Jul 2025

Editorial: Multi-omics and molecular biology studies on abiotic stress in crops

Xiaobo Luo
Georgia Ntatsi
Rong Zhou
Mintao Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1607710

2,077 views

Original Research

Published on 03 Jul 2025

Genome-wide association and functional annotation analyses reveal candidate genes and pathways associated with various ewe longevity indicators in U.S. Katahdin sheep

Luis F. B. Pinto
Ronald M. Lewis
Artur O. Rocha
Brad A. Freking
Tom W. Murphy
Carrie S. Wilson
Sara M. Nilson
Joan M. Burke
Luiz F. Brito

Frontiers in Genetics

doi 10.3389/fgene.2025.1600587

3,818 views
1 citation

Review

Published on 02 Jul 2025

Get ready for short tandem repeats analysis using long reads-the challenges and the state of the art

Marija Chaushevska
Karmele Alapont-Celaya
Anne Kristine Schack
Lukasz Krych
M. Carmen Garrido Navas
Anastasia Krithara
Gjorgji Madjarov

Frontiers in Genetics

doi 10.3389/fgene.2025.1610026

5,562 views
2 citations

Original Research

Published on 02 Jul 2025

Optimizing the single-step model for predicting fumonisins resistance in maize hybrids accounting for the genotype-by-environment interaction

Jeniffer Santana Pinto Coelho Evangelista
Kaio Olimpo das Graças Dias
Maria Marta Pastina
Saulo Chaves
Lauro José Moreira Guimarães
Jorge Hidalgo
Julian Garcia-Abadillo
Reyna Persa
Valéria Aparecida Vieira Queiroz
Dagma Dionísia da Silva

Frontiers in Genetics

doi 10.3389/fgene.2025.1475452

1,888 views

Review

Published on 02 Jul 2025

Current progress and future perspective of super-enhancers: a viable and effective bridge between the transcriptional apparatus and disease

Ran Wang
Aiying Li
Zongran Pang

Frontiers in Genetics

doi 10.3389/fgene.2025.1611905

4,591 views

Case Report

Published on 02 Jul 2025

Case Report: FBN1 mutation screening in South African patients with Marfan syndrome

F. Mhlongo
C. Feben
A. Krause
N. Carstens

Frontiers in Genetics

doi 10.3389/fgene.2025.1612411

2,175 views

Original Research

Published on 02 Jul 2025

Clinical validation of an integrated risk assessment test incorporating genomic and non-genomic data for sporadic breast cancer in Colombia

Harvy Mauricio Velasco Parra
Danny Styvens Cardona
Cesar Augusto Buitrago
Melisa Naranjo Vanegas
Sebastián Gutiérrez Hincapié
Carolina Jaramillo Jaramillo
Alicia Maria Cock-Rada
Carolina Benavides Duque
Clara Patricia Piedrahita
Catalina Bustamante

Frontiers in Genetics

doi 10.3389/fgene.2025.1556907

3,264 views
1 citation

Original Research

Published on 02 Jul 2025

Bioinformatics analysis and experimental validation of ferroptosis genes in heart failure and atrial fibrillation

Zhi Wang
Chi Yuan
Tao Xu
Weixing Xie
Jiehua Wu
Hegui Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1541342

3,581 views

Original Research

Published on 02 Jul 2025

Exploration of biomarkers associated with histone lactylation modification in spinal cord injury

Yisong Sun
Jie Gao
Juehua Jing

Frontiers in Genetics

doi 10.3389/fgene.2025.1609439

3,856 views

Editorial

Published on 02 Jul 2025

Editorial: Recent advances in genomics and oncogenomics for personalized medicine

Sulev Koks

Frontiers in Genetics

doi 10.3389/fgene.2025.1635341

2,284 views

Review

Published on 02 Jul 2025

Conceptualizing the public good for genomics in the global South: a cross-disciplinary roundtable dialogue

Tayyaba Jiwani
Adjua Akinwumi
Jocelyn Cheé-Santiago
Yulia Egorova
Gabriel Frassetto
Ricardo di Lazzaro Filho
Iscia Lopes-Cendes
Mercedes Okumura
José Antonio Alonso Pavón
Alice B. Popejoy

Frontiers in Genetics

doi 10.3389/fgene.2025.1523396

2,898 views
3 citations

Original Research

Published on 02 Jul 2025

FAT1 mutation-related signature predicts survival risk and tumor immunogenicity in lung adenocarcinoma

Lifeng Gao
Xueying Wang
Yixin Xu
Aimin Wang
Wenjing Zhang
Qinghua Wang
Yanfeng Ren

Frontiers in Genetics

doi 10.3389/fgene.2025.1466484

2,363 views
2 citations

Original Research

Published on 02 Jul 2025

Prognostic and tumor microenvironmental features of gastric cancer revealed by macrophage polarization and protein lactylation-related genes

Zifan Xu
Zi Lei
Shilan Peng
Sha Li
Dehui Kong
Hongqiong Duan
Man Zhang
Guomiao Su
Guoqing Pan

Frontiers in Genetics

doi 10.3389/fgene.2025.1541489

3,896 views
1 citation

Original Research

Published on 02 Jul 2025

Rubinstein Taybi syndrome caused by EP300 gene mutation: what we learned from two cases and literature review

Yefeng Wang
Xinghan Wu
Sha Zhao
Ningan Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1588657

2,747 views

963 Publications

volumes

Identification and validation of DNA methylation-driven gene OSR1 as a novel tumor suppressor for the diagnosis and prognosis of breast cancer

Integrating genome and transcriptome analysis to decipher balanced structural variants in unsolved cases of neurodevelopmental disorders

Application of AI in the identification of gastrointestinal stromal tumors: a comprehensive analysis based on pathological, radiological, and genetic variation features

Case Report: The window that closed too soon: lessons from a late CLN2 diagnosis and death of a 9-year-old boy

A novel missense variant of HS6ST2 gene in Paganini-Miozzo syndrome with a rare neurodevelopmental and Endocrine phenotypes

The clinical and genetic profiles of spinal muscular atrophy with respiratory distress type 1 and identification of a novel mutation in IGHMBP2 in China

Genome-wide association study and haplotype analyses reveal the genetic architecture of agronomic traits and sugars in sweet sorghum

Case Report: Surgical management of primary lymphedema with a novel PROX1 mutation involving upper and lower limbs

Statistic tells: the regulatory pendulum of permit trajectories in China’s genetic governance (2021-2024)

Analysis of microRNA expression reveals convergent evolution of the molecular control of diapause in annual killifishes

Editorial: Multi-omics and molecular biology studies on abiotic stress in crops

Genome-wide association and functional annotation analyses reveal candidate genes and pathways associated with various ewe longevity indicators in U.S. Katahdin sheep

Get ready for short tandem repeats analysis using long reads-the challenges and the state of the art

Optimizing the single-step model for predicting fumonisins resistance in maize hybrids accounting for the genotype-by-environment interaction

Current progress and future perspective of super-enhancers: a viable and effective bridge between the transcriptional apparatus and disease

Case Report: FBN1 mutation screening in South African patients with Marfan syndrome

Clinical validation of an integrated risk assessment test incorporating genomic and non-genomic data for sporadic breast cancer in Colombia

Bioinformatics analysis and experimental validation of ferroptosis genes in heart failure and atrial fibrillation

Exploration of biomarkers associated with histone lactylation modification in spinal cord injury

Editorial: Recent advances in genomics and oncogenomics for personalized medicine

Conceptualizing the public good for genomics in the global South: a cross-disciplinary roundtable dialogue

FAT1 mutation-related signature predicts survival risk and tumor immunogenicity in lung adenocarcinoma

Prognostic and tumor microenvironmental features of gastric cancer revealed by macrophage polarization and protein lactylation-related genes

Rubinstein Taybi syndrome caused by EP300 gene mutation: what we learned from two cases and literature review