Frontiers in Genetics

Original Research

Published on 13 Jan 2025

Improving prenatal diagnosis with combined karyotyping, CNV-seq and QF-PCR: a comprehensive analysis of chromosomal abnormalities in high-risk pregnancies

Jia-pei Liu
Shan-Bing Wang
Li Luo
Ya-mei Guo

Frontiers in Genetics

doi 10.3389/fgene.2024.1517270

4,008 views
4 citations

Original Research

Published on 13 Jan 2025

Uncovering somatic mosaic variants of PIK3CA-related overgrowth disorders – three cases with different clinical presentations

M. Tooming
P. Mertsina
T. Kahre
R. Teek
I. Vainumäe
S. Lilles
M. H. Wojcik
P. Ilves
K. Õunap

Frontiers in Genetics

doi 10.3389/fgene.2024.1484651

2,624 views

Clinical Trial

Published on 13 Jan 2025

Genetic variation in patent foramen ovale: a case-control genome-wide association study

Bosi Dong
Yajiao Li
Fandi Ai
Jia Geng
Ting Tang
Wan Peng
Yusha Tang
Hui Wang
Zixuan Tian
Fengxiao Bu

Frontiers in Genetics

doi 10.3389/fgene.2024.1523304

3,135 views
1 citation

Original Research

Published on 10 Jan 2025

Depression-related innate immune genes and pan-cancer gene analysis and validation

Yakun Yang
Wei Han
Xiaoyu Zhang
Hao Yuan
Ran Wang
Jia Yang
Cuixia An
Dongyang Huang

Frontiers in Genetics

doi 10.3389/fgene.2024.1521238

3,691 views
2 citations

Original Research

Published on 10 Jan 2025

Comprehensive analysis of ferroptosis-related genes reveals potential therapeutic targets in osteoporosis patients: a computational analysis and in vitro experiments

Sihui Chen
Yi Jiang
Guoqin Xie
Peng Wu
Jinyu Zhu

Frontiers in Genetics

doi 10.3389/fgene.2024.1522809

3,512 views

Original Research

Published on 09 Jan 2025

Circle-seq reveals that eccDNA may be a key blood biomarker for HBV-associated liver cancer

Xiao K. Ran
Xiao F. Zhao
Zhen W. Wei
Hua Z. Pang
Yan F. Tang
Rong Liu
Tie X. Wu
Xu D. Liu

Frontiers in Genetics

doi 10.3389/fgene.2024.1454153

3,916 views
2 citations

Original Research

Published on 09 Jan 2025

A family with normal sperm motility carrying a sY86 deletion in AZFa region and partial deletion in AZFc region

Yuhong Zhao
Weiwei Zhi
Dongsheng Xiong
Ningjing Li
Xinrong Du
Jiuzhi Zeng
Guohui Zhang
Weixin Liu

Frontiers in Genetics

doi 10.3389/fgene.2024.1519774

2,770 views

Editorial

Published on 09 Jan 2025

Editorial: Pharmacogenetics of psychiatric disorders

Sarah Allegra
Silvia De Francia
Stefano Comità
Maria Grazia Morgese
Thomas M. Polasek

Frontiers in Genetics

doi 10.3389/fgene.2024.1523071

2,110 views

Brief Research Report

Published on 09 Jan 2025

Variability of PRDM9 in buffaloes

Luca Godoi Rocha Santana
Jackeline Santos Alves
Fabieli Loise Braga Feitosa
Victoria Camilla Parente Rocha
Humberto Tonhati
Raphael Bermal Costa
Gregório Miguel Ferreira de Camargo

Frontiers in Genetics

doi 10.3389/fgene.2024.1479287

1,690 views

Original Research

Published on 09 Jan 2025

Single-cell RNA sequencing elucidates cellular plasticity in esophageal small cell carcinoma following chemotherapy treatment

Qinkai Zhang
Ziyu Gao
Ru Qiu
Jizhao Cao
Chunxiao Zhang
Wei Qin
Meiling Yang
Xinyue Wang
Ciqiu Yang
Jie Li

Frontiers in Genetics

doi 10.3389/fgene.2024.1477705

2,806 views
4 citations

Original Research

Published on 08 Jan 2025

DLBWE-Cys: a deep-learning-based tool for identifying cysteine S-carboxyethylation sites using binary-weight encoding

Zhengtao Luo
Qingyong Wang
Yingchun Xia
Xiaolei Zhu
Shuai Yang
Zhaochun Xu
Lichuan Gu

Frontiers in Genetics

doi 10.3389/fgene.2024.1464976

2,374 views
2 citations

Original Research

Published on 08 Jan 2025

Detection of inversion with breakpoints in ARSB causing MPS VI by whole-genome sequencing: lessons learned and best practices

Yufeng Huang
Wenyue Deng
Hui Huang
Xiankai Zhang
Xiaohong Chen
Jian Ye
Sukun Luo
Ting Yu
Hui Yao
Hao Du

Frontiers in Genetics

doi 10.3389/fgene.2024.1452498

1,657 views

Original Research

Published on 08 Jan 2025

Integration of single-cell transcriptomics and bulk transcriptomics to explore prognostic and immunotherapeutic characteristics of nucleotide metabolism in lung adenocarcinoma

Kai Zhang
Luyao Wang
Huili Chen
Lili Deng
Mengling Hu
Ziqiang Wang
Yiluo Xie
Chaoqun Lian
Xiaojing Wang
Jing Zhang

Frontiers in Genetics

doi 10.3389/fgene.2024.1466249

3,003 views

Original Research

Published on 08 Jan 2025

Genotypic variability in stress responses of Sorghum bicolor under drought and salinity conditions

Yahya Alzahrani
Abdulbaki Shehu Abdulbaki
Hameed Alsamadany

Frontiers in Genetics

doi 10.3389/fgene.2024.1502900

2,743 views
6 citations

Original Research

Published on 08 Jan 2025

Genetic insights and therapeutic avenues: unraveling the role of polyunsaturated fatty acids as mediators between hypothyroidism and Von Willebrand disease through Mendelian randomization

Wenting Zhou
Rui He
Ruwei Ou

Frontiers in Genetics

doi 10.3389/fgene.2024.1426401

2,190 views

Review

Published on 08 Jan 2025

Understanding the impacts of drought on peanuts (Arachis hypogaea L.): exploring physio-genetic mechanisms to develop drought-resilient peanut cultivars

Sameer Pokhrel
Prasanna Kharel
Swikriti Pandey
Stephanie Botton
Gema Takbir Nugraha
Corley Holbrook
Peggy Ozias-Akins

Frontiers in Genetics

doi 10.3389/fgene.2024.1492434

8,196 views
13 citations

Original Research

Published on 07 Jan 2025

Phosphorus-solubilizing fungi promote the growth of Fritillaria taipaiensis P. Y. Li by regulating physiological and biochemical reactions and protecting enzyme system–related gene expression

Yueheng Wang
Lin Yuan
Yuhan Wang
Jiaqi Lang
Mingyan Ye
Qingqiu Liu
Qiang Ma
Nong Zhou

Frontiers in Genetics

doi 10.3389/fgene.2024.1459191

2,054 views
4 citations

Case Report

Published on 07 Jan 2025

Facioscapulohumeral muscular dystrophy type 1 combined with becker muscular dystrophy: a family case report

Menglin Tan
Huiyi Huo
Jieming Feng
Chandi Wang
Suhua Jiang

Frontiers in Genetics

doi 10.3389/fgene.2024.1522203

2,954 views
1 citation

Original Research

Published on 07 Jan 2025

Dual disease co-expression analysis reveals potential roles of estrogen-related genes in postmenopausal osteoporosis and Parkinson’s disease

Dongdong Yu
Jian Kang
Chengguo Ju
Qingyan Wang
Ye Qiao
Long Qiao
Dongxiang Yang

Frontiers in Genetics

doi 10.3389/fgene.2024.1518471

3,326 views

Review

Published on 07 Jan 2025

Genomic and physiological mechanisms of high-altitude adaptation in Ethiopian highlanders: a comparative perspective

Wubalem Desta Seifu
Abreham Bekele-Alemu
Changqing Zeng

Frontiers in Genetics

doi 10.3389/fgene.2024.1510932

6,843 views
4 citations

Review

Published on 07 Jan 2025

Recent advances in deep learning and language models for studying the microbiome

Binghao Yan
Yunbi Nam
Lingyao Li
Rebecca A. Deek
Hongzhe Li
Siyuan Ma

Frontiers in Genetics

doi 10.3389/fgene.2024.1494474

10,241 views
7 citations

Original Research

Published on 07 Jan 2025

Co-methylation networks associated with cognition and structural brain development during adolescence

Dawn Jensen
Jiayu Chen
Jessica A. Turner
Julia M. Stephen
Yu-Ping Wang
Tony W. Wilson
Vince D. Calhoun
Jingyu Liu

Frontiers in Genetics

doi 10.3389/fgene.2024.1451150

3,081 views

Original Research

Published on 07 Jan 2025

Mapping the use of cardiovascular genetic services in pediatric clinical care: challenges and opportunities for improvement

Kerstin Hundal
Courtney L. Scherr
Hoda Fakhari
Sanjana Ramesh
Lisa Dellefave-Castillo
Deb Duquette
Sara Cherny
Elizabeth M. McNally
Gregory Webster
Laura J. Rasmussen-Torvik

Frontiers in Genetics

doi 10.3389/fgene.2024.1476466

2,361 views
1 citation

Original Research

Published on 07 Jan 2025

Integrative genomic analyses combined with molecular dynamics simulations reveal the impact of deleterious mutations of Bcl-2 gene on the apoptotic machinery and implications in carcinogenesis

Ghazi Elamin
Zhichao Zhang
Depika Dwarka
Kabange Kasumbwe
John Mellem
Nompumelelo P. Mkhwanazi
Paradise Madlala
Mahmoud E. S. Soliman

Frontiers in Genetics

doi 10.3389/fgene.2024.1502152

3,147 views

16,577 Publications

volumes

Volume 15 - 2024

Improving prenatal diagnosis with combined karyotyping, CNV-seq and QF-PCR: a comprehensive analysis of chromosomal abnormalities in high-risk pregnancies

Uncovering somatic mosaic variants of PIK3CA-related overgrowth disorders – three cases with different clinical presentations

Genetic variation in patent foramen ovale: a case-control genome-wide association study

Depression-related innate immune genes and pan-cancer gene analysis and validation

Comprehensive analysis of ferroptosis-related genes reveals potential therapeutic targets in osteoporosis patients: a computational analysis and in vitro experiments

Circle-seq reveals that eccDNA may be a key blood biomarker for HBV-associated liver cancer

A family with normal sperm motility carrying a sY86 deletion in AZFa region and partial deletion in AZFc region

Editorial: Pharmacogenetics of psychiatric disorders

Variability of PRDM9 in buffaloes

Single-cell RNA sequencing elucidates cellular plasticity in esophageal small cell carcinoma following chemotherapy treatment

DLBWE-Cys: a deep-learning-based tool for identifying cysteine S-carboxyethylation sites using binary-weight encoding

Detection of inversion with breakpoints in ARSB causing MPS VI by whole-genome sequencing: lessons learned and best practices

Integration of single-cell transcriptomics and bulk transcriptomics to explore prognostic and immunotherapeutic characteristics of nucleotide metabolism in lung adenocarcinoma

Genotypic variability in stress responses of Sorghum bicolor under drought and salinity conditions

Genetic insights and therapeutic avenues: unraveling the role of polyunsaturated fatty acids as mediators between hypothyroidism and Von Willebrand disease through Mendelian randomization

Understanding the impacts of drought on peanuts (Arachis hypogaea L.): exploring physio-genetic mechanisms to develop drought-resilient peanut cultivars

Phosphorus-solubilizing fungi promote the growth of Fritillaria taipaiensis P. Y. Li by regulating physiological and biochemical reactions and protecting enzyme system–related gene expression

Facioscapulohumeral muscular dystrophy type 1 combined with becker muscular dystrophy: a family case report

Dual disease co-expression analysis reveals potential roles of estrogen-related genes in postmenopausal osteoporosis and Parkinson’s disease

Genomic and physiological mechanisms of high-altitude adaptation in Ethiopian highlanders: a comparative perspective

Recent advances in deep learning and language models for studying the microbiome

Co-methylation networks associated with cognition and structural brain development during adolescence

Mapping the use of cardiovascular genetic services in pediatric clinical care: challenges and opportunities for improvement

Integrative genomic analyses combined with molecular dynamics simulations reveal the impact of deleterious mutations of Bcl-2 gene on the apoptotic machinery and implications in carcinogenesis