Frontiers in Genetics

Original Research

Published on 01 Dec 2025

Bulk RNA-seq deconvolution heterogeneity across paired pancreatic cancer human samples

Rick J. Jansen
Sarah A. Munro
Samuel O. Antwi
Kari G. Rabe
Hugues Sicotte

Frontiers in Genetics

doi 10.3389/fgene.2025.1662924

1,154 views

Case Report

Published on 01 Dec 2025

Case Report: Pitfalls in CF screening – targeted variant analysis can cause misleading results and therapy recommendations

Maike Karnstedt
Simone Ahting
Sophie Behrendt
Maike vom Hove
Julia Hentschel

Frontiers in Genetics

doi 10.3389/fgene.2025.1693573

979 views

Original Research

Published on 01 Dec 2025

Potential prognostic biomarkers in restenosis of peripheral arteries identified through comprehensive ceRNA network analysis

Yulin Miao
Zongxin Li
Qianqian Sun
Gang Zhao
Guohang Shen
Haobo Zhang
Fengli Gao

Frontiers in Genetics

doi 10.3389/fgene.2025.1597644

1,190 views

Correction

Published on 01 Dec 2025

Correction: Individual and combined effects of the GSTM1, GSTT1, and GSTP1 polymorphisms on type 2 diabetes mellitus risk: a systematic review and meta-analysis

Liang-shu Liu
Di Wang
Ru Tang
Qi Wang
Lu Zheng
Jian Wei
Yan Li
Xiao-feng He

Frontiers in Genetics

doi 10.3389/fgene.2025.1749934

905 views

Correction

Published on 01 Dec 2025

Correction: Computational models for pan-cancer classification based on multi-omics data

Jianlin Wang
Jiao Zhang
Xuebing Dai
Chaokun Yan
Caili Fang

Frontiers in Genetics

doi 10.3389/fgene.2025.1743847

698 views

Case Report

Published on 01 Dec 2025

Case Report: Novel mutations in two patients with MED13L-related intellectual disability highlighting the importance of genetic counseling

Hanyu Cao
Tiantian He
Jing Wang
Cong Zhou
Xing Wei
Xuemei Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1669849

1,006 views

Original Research

Accepted on 30 Nov 2025

An intronic micro-deletion impacts the transcription and translation of PKD1 gene

Xinli Xing
Wei Zheng
Xuejing Sun
Na Wei

Frontiers in Genetics

109 views

Case Report

Published on 28 Nov 2025

Type 1 Bartter syndrome presenting as primary diabetes insipidus: a rare Case Report with 8-year follow-up

Huijuan Lu
Shaojun Liu
Jia Sun
Lijun Mou

Frontiers in Genetics

doi 10.3389/fgene.2025.1672214

996 views

Original Research

Accepted on 27 Nov 2025

Salmonella enterica serovar Typhimurium induced alteration of inflammatory Chemokine mRNA expression and haemato-biochemical variations in three different breeds/strains of chicken

Shabir Mir
Nazir A Ganai
Syed M Ahmad
Ishraq Hussain
Gowhar G Sheikh
Nusrat Nabi
Hassan Rudayni
Ahmed A Allam

Frontiers in Genetics

217 views

Case Report

Published on 27 Nov 2025

Case Report: developmental delay and intellectual disability linked to a maternally inherited derivative chromosome 3 from a t(3;8) translocation

Andrés León
Alex S. Aguirre
Anna Lindstrand
Marlene Ek
Vanessa I. Romero

Frontiers in Genetics

doi 10.3389/fgene.2025.1662915

1,058 views

Original Research

Published on 27 Nov 2025

Development of a senescence-related lncRNA signature in endometrial cancer based on multiple machine learning models

Jie Lin
Xuemei Lei
Yanhong Li
Xin Jiang
Fengle Jiang
Aihua Guo
Xintong Cai
Xingming Ye
Yang Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1687922

1,286 views

Review

Published on 27 Nov 2025

Biogenesis and function of circular RNAs and their implications in the Down syndrome brain

Shahidee Zainal Abidin
Nurul Nadirah Razali
Pike-See Cheah
King-Hwa Ling

Frontiers in Genetics

doi 10.3389/fgene.2025.1708015

1,154 views

Correction

Published on 27 Nov 2025

Correction: Validation of a genome-wide polygenic score for body mass index in South Asians

Ramesh Menon
Nikhat Khan
Sandeep Charugulla
Akshi Bassi
Pooja Dangare
Akshay Dedaniya
Aakanksha Pant
Rammurthy Anjanappa
Praveena L. Samson
Uthra Satagopan

Frontiers in Genetics

doi 10.3389/fgene.2025.1708353

1,213 views

Original Research

Published on 26 Nov 2025

BAG3-related myofibrillar myopathy: focus on its cardiac involvement

Elise Daire
Elena Panaioli
Cyril Gitiaux
Catherine Gardin
Victor Waldmann
Damien Bonnet
Karim Wahbi
Diala Khraiche

Frontiers in Genetics

doi 10.3389/fgene.2025.1636999

1,204 views

Original Research

Published on 26 Nov 2025

Molecular mechanisms of TTC21B gene mutations in nephronophthisis type 12 and genetic prevention through PGT

Kai Deng
Jingjing Li
Xitao Hu
Huijuan Wei
Chenyi Wang
Qingqing Cheng
Yu Jiang
Liyi Cai
Di Tang
Guiju Cao

Frontiers in Genetics

doi 10.3389/fgene.2025.1710252

980 views

Methods

Published on 26 Nov 2025

OFGPMA: Optimal frequency graph representation learning for pseudogene and miRNA association prediction

Yongbin Zeng
Lixiang Xiong
Yungui Luo

Frontiers in Genetics

doi 10.3389/fgene.2025.1643921

861 views

Original Research

Published on 26 Nov 2025

DMAGCL: A dual-masked adaptive graph contrastive learning framework for predicting circRNA-drug sensitivity

Peng Wang
Yuqi Guo
Zejun Li
Di Tang
Mingming Qi
Zhanyi Zhu
Lichao Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1721716

1,058 views
1 citation

Original Research

Published on 26 Nov 2025

Identification and experimental validation of demethylation-related genes in diabetic nephropathy

Hui Miao
Yunke Zhu
Jiaqi Zheng
Chunfeng Deng
Yi Zeng
Fei Tang
Xi Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1675592

1,366 views

Original Research

Published on 25 Nov 2025

Mechanistic study of TFE3 breakage in TFE3-rearranged renal cell carcinoma: the perspective of non-canonical DNA structures and their stability

Xiaopo Zhang
Qinshuang Dang
Xinghe Pan
Zhenggen Deng
Yanhao Xu
Weidong Gan
Hongqian Guo

Frontiers in Genetics

doi 10.3389/fgene.2025.1694739

996 views

Original Research

Published on 25 Nov 2025

Revealing the key modules and potential prognostic markers of gastric cancer transformation based on weighted gene co-expression networks

Heng Li
Wen Li
Zhen Yang
Haiyu Liu
Xiaoping Zhang
Yufeng Zhao
Hao Gu

Frontiers in Genetics

doi 10.3389/fgene.2025.1613682

1,154 views

Original Research

Published on 25 Nov 2025

Genomic analysis reveals genetic diversity and selection signatures of the Yantai Black pig during domestication and breeding

Ming Qin
Cai Ma
Mingzhi Liang
Yuxin Zhang
Zengguang Wang
Jingyu Wang
Guodong Li
Yufen Sha
Peng Jin
Lingling Ju

Frontiers in Genetics

doi 10.3389/fgene.2025.1730668

971 views

Systematic Review

Accepted on 24 Nov 2025

Coffin–Lowry Syndrome: A Systematic Review of RPS6KA3 Confirmed Cases and Implications for Diagnosis and Counseling

Sabyasachi Maity
Miranda Montion
Danielle Boothe
Mona Attarpour
Ivy Mageto
Simran Agarwal
Rujul Patel
Chloe Lark
Nemesis Cardona Valentin
Esther Quinones Budel

Frontiers in Genetics

222 views

Original Research

Accepted on 24 Nov 2025

Genomic and Ancestral Variations linked to the Development of Post-Acute Sequelae of SARS-CoV-2 infection in Indian Populations

Pooja Shenoy
Hrushikesh Udupa
Ananthakrishnan A.I
Punya Sunil
Urvinder Kaur Sardarni
Narendra Kumar
Arpan Acharya
Siddappa N Byrareddy
Priyanka Upadhyai
Ranajit Das

Frontiers in Genetics

334 views

Correction

Published on 24 Nov 2025

Correction: Non-coding RNAs in heart failure: epigenetic regulatory mechanisms and therapeutic potential

Yubo Ren
Bomeng Zhao
Luo Lv
Jingyuan Yang
Xiangting Nan
Bao Li
Bin Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1746339

678 views

963 Publications

volumes

Bulk RNA-seq deconvolution heterogeneity across paired pancreatic cancer human samples

Case Report: Pitfalls in CF screening – targeted variant analysis can cause misleading results and therapy recommendations

Potential prognostic biomarkers in restenosis of peripheral arteries identified through comprehensive ceRNA network analysis

Correction: Individual and combined effects of the GSTM1, GSTT1, and GSTP1 polymorphisms on type 2 diabetes mellitus risk: a systematic review and meta-analysis

Correction: Computational models for pan-cancer classification based on multi-omics data

Case Report: Novel mutations in two patients with MED13L-related intellectual disability highlighting the importance of genetic counseling

An intronic micro-deletion impacts the transcription and translation of PKD1 gene

Type 1 Bartter syndrome presenting as primary diabetes insipidus: a rare Case Report with 8-year follow-up

Salmonella enterica serovar Typhimurium induced alteration of inflammatory Chemokine mRNA expression and haemato-biochemical variations in three different breeds/strains of chicken

Case Report: developmental delay and intellectual disability linked to a maternally inherited derivative chromosome 3 from a t(3;8) translocation

Development of a senescence-related lncRNA signature in endometrial cancer based on multiple machine learning models

Biogenesis and function of circular RNAs and their implications in the Down syndrome brain

Correction: Validation of a genome-wide polygenic score for body mass index in South Asians

BAG3-related myofibrillar myopathy: focus on its cardiac involvement

Molecular mechanisms of TTC21B gene mutations in nephronophthisis type 12 and genetic prevention through PGT

OFGPMA: Optimal frequency graph representation learning for pseudogene and miRNA association prediction

DMAGCL: A dual-masked adaptive graph contrastive learning framework for predicting circRNA-drug sensitivity

Identification and experimental validation of demethylation-related genes in diabetic nephropathy

Mechanistic study of TFE3 breakage in TFE3-rearranged renal cell carcinoma: the perspective of non-canonical DNA structures and their stability

Revealing the key modules and potential prognostic markers of gastric cancer transformation based on weighted gene co-expression networks

Genomic analysis reveals genetic diversity and selection signatures of the Yantai Black pig during domestication and breeding

Coffin–Lowry Syndrome: A Systematic Review of RPS6KA3 Confirmed Cases and Implications for Diagnosis and Counseling

Genomic and Ancestral Variations linked to the Development of Post-Acute Sequelae of SARS-CoV-2 infection in Indian Populations

Correction: Non-coding RNAs in heart failure: epigenetic regulatory mechanisms and therapeutic potential