Frontiers in Genetics

Original Research

Published on 06 Dec 2024

Real-world efficacy and safety of combined first-line treatment with PARP inhibitors and novel hormonal therapy in mCRPC patients with HRR gene mutations

Andong Guo
Chenrui Wu
Jishuang Cao
Kejia Zhu
Sentai Ding

Frontiers in Genetics

doi 10.3389/fgene.2024.1505163

1,999 views

Editorial

Published on 05 Dec 2024

Editorial: CRISPR: the game changer in gene and cell therapy

Wenxia He
Meizhu Bai

Frontiers in Genetics

doi 10.3389/fgene.2024.1517298

2,526 views

Original Research

Published on 05 Dec 2024

Metabolic dysfunction-associated steatotic liver disease and gastroesophageal reflux disease: a mendelian randomization study in European and East Asian populations

Chen’guang Su
Zheng Liao
Hewen Li
Yinxuan Pei
Zixiang Wang
Jian Li
Jinlong Liu

Frontiers in Genetics

doi 10.3389/fgene.2024.1428334

2,792 views
1 citation

Original Research

Published on 05 Dec 2024

Exploring the impact of deubiquitination on melanoma prognosis through single-cell RNA sequencing

Su Peng
Jiaheng Xie
Xiaohu He

Frontiers in Genetics

doi 10.3389/fgene.2024.1509049

2,053 views
1 citation

Original Research

Published on 05 Dec 2024

BIRC5 as a prognostic and diagnostic biomarker in pan-cancer: an integrated analysis of expression, immune subtypes, and functional networks

Guoyu Li
Yanghao Wang
Weizhou Wang
Guodong Lv
Xiang Li
Jingying Wang
Xiuyu Liu
Daolang Yuan
Shoujun Deng
Dingyun You

Frontiers in Genetics

doi 10.3389/fgene.2024.1509342

3,691 views
8 citations

Case Report

Published on 05 Dec 2024

Case report: A single novel calpain 3 gene variant associated with mild myopathy

Sara Massucco
Paola Fossa
Chiara Fiorillo
Elena Faedo
Chiara Gemelli
Rita Barresi
Michela Ripolone
Serena Patrone
Andrea Gaudio
Paola Mandich

Frontiers in Genetics

doi 10.3389/fgene.2024.1437859

2,049 views
1 citation

Correction

Published on 04 Dec 2024

Corrigendum: Immune regulation and prognostic prediction model establishment and validation of PSMB6 in lung adenocarcinoma

Haiyang Zhao
Kexin Luo
Meihan Liu
Yuanze Cai
Siman Liu
Shijuan Li
Yongsheng Zhao
Hongpan Zhang

Frontiers in Genetics

doi 10.3389/fgene.2024.1531321

1,123 views

Original Research

Published on 04 Dec 2024

Systematic pharmacology-based strategy to investigate the mechanism of beta-sitosterol for the treatment of rheumarthritis

Xiaodong Wang
Jingxin Mao

Frontiers in Genetics

doi 10.3389/fgene.2024.1507606

3,412 views
4 citations

Case Report

Published on 04 Dec 2024

Case report: A novel nonsense mutation in the MARVELD2 gene causes nonsyndromic hearing loss in a China family

Chuican Huang
Zhenning Huang
Ping Wang
Xijing Wu
Qiaomiao Zhou
Jun Ding
Qing Luo
Weijia Wu
Xialin Fan
Lichun Fan

Frontiers in Genetics

doi 10.3389/fgene.2024.1507600

1,576 views

Original Research

Published on 04 Dec 2024

Gene expression ranking change based single sample pre-disease state detection

Zhenshen Bao
Xianbin Li
Peng Xu
Xiangzhen Zan

Frontiers in Genetics

doi 10.3389/fgene.2024.1509769

1,409 views

Original Research

Published on 04 Dec 2024

Identification of potential biomarkers from amino acid transporter in the activation of hepatic stellate cells via bioinformatics

Yingying Zhao
Xueqing Xu
Huaiyang Cai
Wenhong Wu
Yingwei Wang
Cheng Huang
Heping Qin
Shuangyang Mo

Frontiers in Genetics

doi 10.3389/fgene.2024.1499915

2,415 views

Brief Research Report

Published on 04 Dec 2024

Workplace genetic testing: which employees are likely to participate, what are their concerns with employer sponsorship, and which design features could reduce barriers and increase participation?

Forrest Briscoe
James H. Maxwell
Angel Bourgoin

Frontiers in Genetics

doi 10.3389/fgene.2024.1496900

2,418 views
3 citations

Methods

Published on 04 Dec 2024

OCRClassifier: integrating statistical control chart into machine learning framework for better detecting open chromatin regions

Xin Lai
Min Liu
Yuqian Liu
Xiaoyan Zhu
Jiayin Wang

Frontiers in Genetics

doi 10.3389/fgene.2024.1400228

1,282 views

Original Research

Published on 03 Dec 2024

Phylogeography, taxonomy, and conservation of the endangered brown howler monkey, Alouatta guariba (Primates, Atelidae), of the Atlantic Forest

Luciana I. Oklander
Gabriela P. Fernández
Stela Machado
Mariela Caputo
Zelinda M. B. Hirano
Anthony B. Rylands
Leonardo G. Neves
Sérgio L. Mendes
Luciana G. Pacca
Fabiano R. de Melo

Frontiers in Genetics

doi 10.3389/fgene.2024.1453005

6,264 views
2 citations

Original Research

Published on 02 Dec 2024

Genetic surveillance shows spread of ACT resistance during period of malaria decline in Vietnam (2018-2020)

Johanna Helena Kattenberg
Mathijs Mutsaers
Van Hong Nguyen
Thi Hong Ngoc Nguyen
Arlette Umugwaneza
Maria Lara-Escandell
Xuan Xa Nguyen
Thi Huong Binh Nguyen
Anna Rosanas-Urgell

Frontiers in Genetics

doi 10.3389/fgene.2024.1478706

5,052 views
2 citations

Original Research

Published on 02 Dec 2024

Adaptable and comprehensive approaches for long-read nanopore sequencing of polyadenylated and non-polyadenylated RNAs

Simon Haile
Richard D. Corbett
Kieran O’Neill
Jing Xu
Duane E. Smailus
Pawan K. Pandoh
Anthony Bayega
Miruna Bala
Eric Chuah
Robin J. N. Coope

Frontiers in Genetics

doi 10.3389/fgene.2024.1466338

3,358 views

Editorial

Published on 02 Dec 2024

Editorial: Recent advances in understanding the genetics of immunological disorders

Che Kang Lim
Hassan Abolhassani
Jinqiao Sun

Frontiers in Genetics

doi 10.3389/fgene.2024.1530187

1,797 views

Original Research

Published on 02 Dec 2024

SOLA: dissecting dose-response patterns in multi-omics data using a semi-supervised workflow

Wanxin Lai
You Song
Knut Erik Tollefsen
Torgeir R. Hvidsten

Frontiers in Genetics

doi 10.3389/fgene.2024.1508521

2,119 views

Original Research

Published on 02 Dec 2024

Fatty acid traits mediate the effects of uric acid on cancers: a Mendelian randomization study

Jianing Li
Yongsheng Zhang
Tong Fu
Songyan Wang
Hongbo Cai
Fenghua Xu
Guoli Xing
Ying Tong

Frontiers in Genetics

doi 10.3389/fgene.2024.1449205

3,943 views
4 citations

Original Research

Published on 02 Dec 2024

Assessment of genetic structure and trait associations of Watkins wheat landraces under Egyptian field conditions

Ahmed Fawzy Elkot
Ahmed E. Nassar
Elsayed L. Elmassry
Macarena Forner-Martínez
Rajani Awal
Luzie U. Wingen
Simon Griffiths
Alsamman M. Alsamman
Zakaria Kehel

Frontiers in Genetics

doi 10.3389/fgene.2024.1384220

2,055 views

Original Research

Published on 29 Nov 2024

Whole mitochondrial genome analyses of Han population from Shandong of China using massively parallel sequencing

Jiashuo Zhang
XueBo Li
Anqi Chen
Mingxia Ding
Liangliang Li
Yinghua Qi
Chunli Ding
Dawei Cai
Suhua Zhang

Frontiers in Genetics

doi 10.3389/fgene.2024.1513412

3,586 views

Systematic Review

Published on 29 Nov 2024

Consumer-oriented (patient and family) outcomes from nursing in genomics: a scoping review of the literature (2012–2022)

Jordan N. Keels
Joanne Thomas
Kathleen A. Calzone
Laurie Badzek
Sarah Dewell
Vinaya Murthy
Rosie O’Shea
Emma T. Tonkin
Andrew A. Dwyer

Frontiers in Genetics

doi 10.3389/fgene.2024.1481948

4,674 views
2 citations

Review

Published on 29 Nov 2024

PARP inhibitors in testicular germ cell tumors: what we know and what we are looking for

Sara Parola
Christoph Oing
Pasquale Rescigno
Salvatore Feliciano
Francesca Carlino
Luca Pompella
Antonella Lucia Marretta
Irene De Santo
Martina Viggiani
Margherita Muratore

Frontiers in Genetics

doi 10.3389/fgene.2024.1480417

2,447 views
2 citations

Brief Research Report

Published on 29 Nov 2024

Genewise detection of variants in MEFV gene using nanopore sequencing

Lilit Ghukasyan
Gisane Khachatryan
Tamara Sirunyan
Arpine Minasyan
Siras Hakobyan
Andranik Chavushyan
Varduhi Hayrapetyan
Hovsep Ghazaryan
Gevorg Martirosyan
Gohar Mkrtchyan

Frontiers in Genetics

doi 10.3389/fgene.2024.1493295

2,987 views
1 citation

1,121 Publications

volumes

Real-world efficacy and safety of combined first-line treatment with PARP inhibitors and novel hormonal therapy in mCRPC patients with HRR gene mutations

Editorial: CRISPR: the game changer in gene and cell therapy

Metabolic dysfunction-associated steatotic liver disease and gastroesophageal reflux disease: a mendelian randomization study in European and East Asian populations

Exploring the impact of deubiquitination on melanoma prognosis through single-cell RNA sequencing

BIRC5 as a prognostic and diagnostic biomarker in pan-cancer: an integrated analysis of expression, immune subtypes, and functional networks

Case report: A single novel calpain 3 gene variant associated with mild myopathy

Corrigendum: Immune regulation and prognostic prediction model establishment and validation of PSMB6 in lung adenocarcinoma

Systematic pharmacology-based strategy to investigate the mechanism of beta-sitosterol for the treatment of rheumarthritis

Case report: A novel nonsense mutation in the MARVELD2 gene causes nonsyndromic hearing loss in a China family

Gene expression ranking change based single sample pre-disease state detection

Identification of potential biomarkers from amino acid transporter in the activation of hepatic stellate cells via bioinformatics

Workplace genetic testing: which employees are likely to participate, what are their concerns with employer sponsorship, and which design features could reduce barriers and increase participation?

OCRClassifier: integrating statistical control chart into machine learning framework for better detecting open chromatin regions

Phylogeography, taxonomy, and conservation of the endangered brown howler monkey, Alouatta guariba (Primates, Atelidae), of the Atlantic Forest

Genetic surveillance shows spread of ACT resistance during period of malaria decline in Vietnam (2018-2020)

Adaptable and comprehensive approaches for long-read nanopore sequencing of polyadenylated and non-polyadenylated RNAs

Editorial: Recent advances in understanding the genetics of immunological disorders

SOLA: dissecting dose-response patterns in multi-omics data using a semi-supervised workflow

Fatty acid traits mediate the effects of uric acid on cancers: a Mendelian randomization study

Assessment of genetic structure and trait associations of Watkins wheat landraces under Egyptian field conditions

Whole mitochondrial genome analyses of Han population from Shandong of China using massively parallel sequencing

Consumer-oriented (patient and family) outcomes from nursing in genomics: a scoping review of the literature (2012–2022)

PARP inhibitors in testicular germ cell tumors: what we know and what we are looking for

Genewise detection of variants in MEFV gene using nanopore sequencing