Frontiers in Genetics

Original Research

Published on 17 Nov 2025

Genetic background of behavior traits in lactating sows under heat-stress conditions and their relationship with heat tolerance and maternal performance traits

Sharlene O. Hartman
Lorena F. Benfica
Jay S. Johnson
Jeremy N. Marchant
Hinayah R. Oliveira
Victor B. Pedrosa
Allan P. Schinckel
Yijian Huang
Leonardo S. Gloria
Hui Wen

Frontiers in Genetics

doi 10.3389/fgene.2025.1688262

1,271 views

Case Report

Published on 14 Nov 2025

Familial Xq27.1q28 duplication arising from a maternal interarm forward insertion of the X chromosome: a case report

Xiang Li
Yuan-Mei Peng
Bo-Wen Luo
Yu-Di Luo
Yun-Rong Qin
Keng Feng
De-Rong Li
Zeng-Yu Yang
Ling-Ling Zhu
Jin-Jie Pan

Frontiers in Genetics

doi 10.3389/fgene.2025.1514856

1,296 views

Original Research

Published on 14 Nov 2025

Novel variant in PNPLA6 gene causes Oliver-McFarlane syndrome in a Chinese family: 13 years follow-up

Panpan Xiao
Yonghua Gu
Xiaolong Qi
Ting Li
Tingting Zuo
Yule Xie
Shuang Zhang
Xunlun Sheng

Frontiers in Genetics

doi 10.3389/fgene.2025.1693876

886 views

Case Report

Published on 14 Nov 2025

Case Report: Identification and functional characterization of a novel heterozygous splice-donor (c.647+1G>A) site mutation in the SPTB gene that causes hereditary spherocytosis with hemolytic anemia

Ke Cao
Xiaojuan Luo
Lianlian Liu
Xiaoning Mao
Ruping Liu
Yunsheng Chen
Santasree Banerjee

Frontiers in Genetics

doi 10.3389/fgene.2025.1626155

1,048 views

Original Research

Accepted on 13 Nov 2025

Impact of rs7528684 (-169T/C) on FCRL3, FOXP3, IL-35 Gene Expression and IgG-RF Correlation: Insights into Rheumatoid Arthritis Pathogenesis

Asha Devi S
Mohamed Muzammil.s

Frontiers in Genetics

246 views

Review

Published on 13 Nov 2025

Emerging roles of natural killer cell ligands—HLA-E, HLA-F, HLA-G, MICA, and MICB—in in vitro fertilization outcomes

Itta Krishna Chaaithanya
Raja Rajalingam

Frontiers in Genetics

doi 10.3389/fgene.2025.1661511

1,620 views

Original Research

Published on 13 Nov 2025

Distribution characteristics of MTHFR C677T gene polymorphism in Han nationality and women of childbearing age in 8 regions of Shaanxi province and a comparative analysis with other regions in China

Ting Chen
Fei Song
Jinyao Sun
Jing Yi
Wenbing Ma

Frontiers in Genetics

doi 10.3389/fgene.2025.1693729

1,346 views

Brief Research Report

Published on 12 Nov 2025

Building capability for clinician-led genomic change: insights from use and non-use of a theory-informed model for change

Melissa Martyn
Amy Clarke
Trang Do
Belinda Dawson-McClaren
Clara Gaff

Frontiers in Genetics

doi 10.3389/fgene.2025.1692703

1,541 views
1 citation

Original Research

Published on 12 Nov 2025

The genetic diversity and population structure of native horse breeds in Xinjiang, China

Chi Tang
Baoyu Yang
Gulibaheti Dawulietihan
Li Xue
Shuyuan Liu
Yinamujiang Yalimaimaiti
Qingzheng Wang
Na Yang
Xiaoyuan Sun
Yaru Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1439312

2,271 views

Correction

Published on 12 Nov 2025

Correction: Drought adaptation index (DAI) based on BLUP as a selection approach for drought-resilient switchgrass germplasm

Shiva Om Makaju
Hari Bahadur Chhetri
Chanaka Roshan Abeyratne
Mirko Pavicic
Hari Poudel
Jazib Ali Irfan
Anita Giabardo
Katrien M. Devos
Daniel Jacobson
Ali Mekki Missaoui

Frontiers in Genetics

doi 10.3389/fgene.2025.1731825

610 views

Correction

Published on 12 Nov 2025

Correction: Integrative machine learning and Mendelian randomization identify causal laboratory biomarkers for coronary artery lesions in Kawasaki disease: a prospective study

Hancao Yang
Meng Wu
Keqing Liang
Yi Li
Ran Yang
Beibei Yuan
Ming Wu
Jin Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1735649

650 views

Original Research

Published on 12 Nov 2025

CELF1 promotes aerobic glycolysis and an aggressive phenotype in ER-positive breast cancer via GLUT1 regulation

Jinyu Li
Ning Wang
Jianlei Bi
Meihua Guo
Bingbing Xu
Gena Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1687066

1,447 views

Case Report

Published on 12 Nov 2025

Case Report: Compound heterozygous CEP152 c.3346-5T>C variant and chr15 deletion causing recurrent MCPH–SCKS in a Chinese pregnant woman across two consecutive pregnancies

Tao Zhang
Hua Yuan
Xiaoliang Shi
Yao He
Haitao Pan
Yongxing Zhong
Jintang Zhang
Zhen Yang
Yunyan Ke
Yan Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1646297

1,194 views

Original Research

Published on 12 Nov 2025

Computational-experimental strategy identifies Co-upregulated biomarkers linking coronary heart disease and type 2 diabetes pathogenesis

Wei Li
Yu Cao
Chen Yu
Bingjun Che
Miao He
Dongbiao Li
Lihong Jiang
Lijing Ma

Frontiers in Genetics

doi 10.3389/fgene.2025.1673303

1,021 views

Review

Published on 11 Nov 2025

Ocular surface health and disease: insight from single-cell RNA sequencing

Shangkun Ou
Minqing Cai
Yuchong Feng
Sijie Lin
Xueer Zheng
Su Zhao
Hao Gu
Yiming Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1683167

1,689 views

Mini Review

Published on 11 Nov 2025

Epigenetic landscape in lysosomal storage disorders: mechanisms and modulation

Andrés Felipe Leal
Harry Pachajoa
Shunji Tomatsu

Frontiers in Genetics

doi 10.3389/fgene.2025.1679497

1,610 views

Original Research

Published on 11 Nov 2025

Germline activating sequence variations in RASopathy spectrum genes: genotype–phenotype correlation in a North Indian cohort

Shifali Gupta
Priyanka Srivastava
Roshan Daniel
Chitra Bhardwaj
Parminder Kaur
Pratibha Bawa
Anu Kumari
Ravi Pratap Singh Bhadoriya
Mrinali Peters
Anupriya Kaur

Frontiers in Genetics

doi 10.3389/fgene.2025.1677143

1,503 views

Original Research

Published on 10 Nov 2025

Genotyping strategies for single-step genomic predictions in a simulated sheep population under different scenarios of pedigree error types

Artur O. Rocha
Leonardo S. Gloria
Andre C. Araujo
Hui Wen
Carrie S. Wilson
Bradley A. Freking
Thomas W. Murphy
Joan M. Burke
Ronald M. Lewis
Luiz F. Brito

Frontiers in Genetics

doi 10.3389/fgene.2025.1697103

2,449 views

Original Research

Published on 10 Nov 2025

Unveiling disulfidptosis-linked lncRNA signatures: insights into the immune microenvironment and drug responsiveness in oral squamous cell carcinoma

Xue Meng
Lichao Cao
Yantao Liu
Sihan Wang
Weixian Liu
Guangping Zhang
Siqi Guo
Fangyu Qi
Tingting Wang
Yuhe Xia

Frontiers in Genetics

doi 10.3389/fgene.2025.1650544

1,171 views

Original Research

Published on 10 Nov 2025

Construction of a HSC activation-related lncRNA–miRNA–mRNA ceRNA regulatory network reveals potential molecules involved in liver fibrosis

Kaiqiang Wan
Qiong Zhou
Ruirui Feng
Tao Liu
Chang Fan
Xue Pang
Zhongliang Li
Qiumei Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1640326

1,463 views

Original Research

Published on 10 Nov 2025

Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) leaves

Ting Yang
Xiaolu Lin
Rui Chen
Ruiqi Wang
Tong Li
Fulong Shen
Xiaowei Zhang
Lianghua Lai
Bing Lu
Jiliang Wei

Frontiers in Genetics

doi 10.3389/fgene.2025.1662815

1,314 views

Mini Review

Published on 10 Nov 2025

Advances in post-processing methods for multiple sequence alignment

Yixiao Zhai
Zitong Zhang
Zhen Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1722317

1,452 views

Original Research

Published on 07 Nov 2025

KSRV: a Kernel PCA-Based framework for inferring spatial RNA velocity at single-cell resolution

Yan He
Jian Jiang
Huahai Qiu
Ya-Zhou Shi
Ben-Gong Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1695803

1,507 views

Original Research

Published on 07 Nov 2025

Mechanistic insights into NFIX frameshift mutations in Malan syndrome: proteasomal degradation-mediated haploinsufficiency

Yan Zhou
Linbing Zou
Yaoyao Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1648420

1,163 views

963 Publications

volumes

Genetic background of behavior traits in lactating sows under heat-stress conditions and their relationship with heat tolerance and maternal performance traits

Familial Xq27.1q28 duplication arising from a maternal interarm forward insertion of the X chromosome: a case report

Novel variant in PNPLA6 gene causes Oliver-McFarlane syndrome in a Chinese family: 13 years follow-up

Case Report: Identification and functional characterization of a novel heterozygous splice-donor (c.647+1G>A) site mutation in the SPTB gene that causes hereditary spherocytosis with hemolytic anemia

Impact of rs7528684 (-169T/C) on FCRL3, FOXP3, IL-35 Gene Expression and IgG-RF Correlation: Insights into Rheumatoid Arthritis Pathogenesis

Emerging roles of natural killer cell ligands—HLA-E, HLA-F, HLA-G, MICA, and MICB—in in vitro fertilization outcomes

Distribution characteristics of MTHFR C677T gene polymorphism in Han nationality and women of childbearing age in 8 regions of Shaanxi province and a comparative analysis with other regions in China

Building capability for clinician-led genomic change: insights from use and non-use of a theory-informed model for change

The genetic diversity and population structure of native horse breeds in Xinjiang, China

Correction: Drought adaptation index (DAI) based on BLUP as a selection approach for drought-resilient switchgrass germplasm

Correction: Integrative machine learning and Mendelian randomization identify causal laboratory biomarkers for coronary artery lesions in Kawasaki disease: a prospective study

CELF1 promotes aerobic glycolysis and an aggressive phenotype in ER-positive breast cancer via GLUT1 regulation

Case Report: Compound heterozygous CEP152 c.3346-5T>C variant and chr15 deletion causing recurrent MCPH–SCKS in a Chinese pregnant woman across two consecutive pregnancies

Computational-experimental strategy identifies Co-upregulated biomarkers linking coronary heart disease and type 2 diabetes pathogenesis

Ocular surface health and disease: insight from single-cell RNA sequencing

Epigenetic landscape in lysosomal storage disorders: mechanisms and modulation

Germline activating sequence variations in RASopathy spectrum genes: genotype–phenotype correlation in a North Indian cohort

Genotyping strategies for single-step genomic predictions in a simulated sheep population under different scenarios of pedigree error types

Unveiling disulfidptosis-linked lncRNA signatures: insights into the immune microenvironment and drug responsiveness in oral squamous cell carcinoma

Construction of a HSC activation-related lncRNA–miRNA–mRNA ceRNA regulatory network reveals potential molecules involved in liver fibrosis

Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) leaves

Advances in post-processing methods for multiple sequence alignment

KSRV: a Kernel PCA-Based framework for inferring spatial RNA velocity at single-cell resolution

Mechanistic insights into NFIX frameshift mutations in Malan syndrome: proteasomal degradation-mediated haploinsufficiency