Frontiers in Genome Editing

Original Research

Accepted on 08 Jul 2025

CATS: A Bioinformatic Tool for Automated Cas9 Nucleases activity comparison in clinically relevant contexts

in Genome Editing Tools and Mechanisms

Ettore Rocchi
Federico Magnani
Gastone Castellani
Antonio Carusillo
Martina Tarozzi

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1571023

Original Research

Published on 02 Jul 2025

Simply cut out – Combining CRISPR/Cas9 RNPs and transiently selected telomere vectors for marker free-gene deletion in Trichoderma atroviride

in Genome Editing Tools and Mechanisms

Mario Gründlinger
Chiara Ellensohn
Leo Drechsel
Ulrike Schreiner
Siebe Pierson
Clara Baldin
Susanne Zeilinger

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1623963

546 views

Methods

Published on 01 Jul 2025

Comprehensive approaches to design efficient gRNA for SDN1-CRISPR/Cas9 genome editing in wheat

in Genome Editing in Plants

Tushadri Singh
H. M. Mamrutha
Rajender Singh
J. P. Jaiswal
Zeenat Wadhwa
Rakesh Kumar
Omvir Singh
O. P. Ahlawat
Ratan Tiwari

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1579165

743 views

Brief Research Report

Published on 30 Jun 2025

DNA-free CRISPR genome editing in raspberry (Rubus idaeus) protoplast through RNP-mediated transfection

in Genome Editing in Plants

Ryan Creeth
Andrew Thompson
Zoltan Kevei

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1589431

838 views

Review

Published on 30 Jun 2025

Genome editing for sustainable agriculture in Peru: advances, potential applications and regulation

in Genome Editing in Plants

Marilu Mestanza
Angel David Hernández-Amasifuen
Alexandra Jherina Pineda-Lázaro
Dennis Eriksson
Juan Carlos Guerrero-Abad

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1611040

1,216 views

Brief Research Report

Accepted on 24 Jun 2025

Prime editing using paired pegRNAs targeting NG-or NGG-PAM in rice

in Genome Editing in Plants

Ayako Nishizawa-Yokoi
Keiko Iida
Akiko Mori
Seiichi Toki

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1550308

243 views

Brief Research Report

Accepted on 23 Jun 2025

"CRISPR-Cas9 Editing of TNFAIP3 Variants in Salivary Gland Epithelial Cells to Study Sjögren's Disease Pathogenesis"

in Genome Editing in Human Health and Disease

Subhashis Ghosh
Qisheng Tu
Zoe Xiaofang Zhu
Sreelakshmi Panginikkod
Jake Chen

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1625393

327 views

Brief Research Report

Published on 18 Jun 2025

A long shelf-life melon created via CRISPR/Cas9 RNP-based in planta genome editing

in Genome Editing in Plants

Kentaro Sasaki
Kaoru Urano
Naozumi Mimida
Satoko Nonaka
Hiroshi Ezura
Ryozo Imai

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1623097

1,144 views

Original Research

Published on 04 Jun 2025

Long read sequencing reveals transgene concatemerization and vector sequences integration following AAV-driven electroporation of CRISPR RNP complexes in mouse zygotes

in Genome Editing in Animals

Muhammad W. Luqman
Piroon Jenjaroenpun
Jessica Spathos
Nikhil Shingte
Mitchell Cummins
Pattaraporn Nimsamer
Lars M. Ittner
Thidathip Wongsurawat
Fabien Delerue

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1582097

1,935 views

Review

Published on 03 Jun 2025

Recent developments, challenges and opportunities in genome editing for crop science from a societal perspective

in Genome Editing in Plants

Srividhya Venkataraman
David Zaruk
Kathleen Hefferon

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1568072

1,625 views

Methods

Published on 30 May 2025

Lentiviral CRISPRa/i in the adult prairie vole brain: modulating neuronal gene expression without DNA cleavage

in Genome Editing in Animals

Meredith K. Loth
Kendall T. Mesch
Celine Herrera-Garcia
Liza E. Brusman
Zoe R. Donaldson

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1602983

1,177 views

Editorial

Published on 22 May 2025

Editorial: Plant breeding innovations—CRISPR as a powerful weapon for agricultural crops

in Genome Editing in Plants

Basavantraya N. Devanna
Yugander Arra
Maganti Sheshu Madhav

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1623540

1,758 views

Review

Published on 21 May 2025

Base editors in zebrafish: a new era for functional genomics and disease modeling

in Genome Editing in Animals

Yuwen Liu
Chao Li
Yiren Qiu
Sihong Chen
Yijun Luo
Donghua Xiong
Jun Zhao
Jianmin Ye
Xuegeng Wang
Wei Qin

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1598887

1,669 views

Review

Published on 20 May 2025

Genome editing in grain legumes for food security

in Genome Editing in Plants

Joshua Yeboah Asiamah
Sakina Haruna Mahdi
Kusum R. Tamang
Christian Bryan Carson
Prabesh Koirala
Emily Anne Reed
Aaron Tettey Asare
Anu Augustine
Milind B. Ratnaparkhe
Kailash C. Bansal

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1572292

2,572 views

Original Research

Published on 30 Apr 2025

Efficient GBA1 editing via HDR with ssODNs by outcompeting pseudogene-mediated gene conversion upon CRISPR/Cas9 cleavage

in Genome Editing in Human Health and Disease

Joseph S. Lagas
Monica F. Sentmanat
Xiaoxia Cui

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1581743

1,840 views

Perspective

Accepted on 24 Apr 2025

Ethical Dimensions and Societal Implications: Ensuring the Social Responsibility of CRISPR Technology

in Genome Editing in Human Health and Disease

Irfan Biswas

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1593172

672 views