Frontiers in Genome Editing

Mini Review

Published on 16 Dec 2025

Therapeutic applications of CRISPR-Cas9 gene editing

Aditya Bharti
Joann Mudge

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1724291

1,228 views

Review

Accepted on 09 Dec 2025

CRISPR/Cas9-Based Programmable Genome Editing in Chickens: Concepts, applications and regulatory issues

GAUTHAM KOLLURI
Adnan Naim
Shiva Kumar
Jagbir Singh Tyagi
Mohammed Matin Ansari
Simmi Tomar
Ashok Kumar Tiwari
Laxmi Chouhan

Frontiers in Genome Editing

441 views

Original Research

Published on 04 Dec 2025

Development of efficient targeted insertion mediated by CRISPR-Cas12a and homology-directed repair in maize

Brenden Barco
Shujie Dong
Yuki Matsuba
Ashley Crook
Ruiji Xu
Yingxiao Zhang
Chengjin Zhang
Ryan Carlin
Kevin Potter
Stephen B. Rigoulot

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1713347

1,627 views

Review

Published on 04 Dec 2025

Emerging tools in plant genome editing

Shilpi Sharma
Naveen Kumar Saroha
Abhilasha Sehrawat
Guiliang Tang
Deepali Singh
Sachin Teotia

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1588089

1,991 views

Original Research

Published on 26 Nov 2025

CRISPR-Cas9 mediated editing of starch branching enzyme, SBE2 gene in potato for enhanced resistant starch for health benefits

Sudha Batta
Sundaresha Siddappa
Neha Sharma
Rajender Singh
Reena Gupta
Dinesh Kumar
Brajesh Singh
Ajay Kumar Thakur

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1686412

1,560 views

Editorial

Published on 25 Nov 2025

Editorial: Social aspects of crop genome editing

Srividhya Venkataraman
Kathleen Hefferon

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1740380

1,435 views

Original Research

Published on 20 Nov 2025

Construction of EpCAM overexpression and knockdown vectors and their implications in colorectal cancer research

Bingping Wang
Jinkai Duan
Jie Zhou
Hulin Ma
Meng Ren
Liangquan Chen
Rina Su
Hao Zhang
Shuang Zhang
Yanwei Gao

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1679698

1,037 views

Review

Published on 11 Nov 2025

A long journey towards genome editing technologies in plants: a technical and critical review of genome editing technologies

Dylan Gallo
Anne-Cécile Meunier
Christophe Périn

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1663352

1,751 views

Correction

Published on 07 Nov 2025

Correction: Rewriting the script: gene therapy and genome editing for von Willebrand Disease

Alastair Barraclough
Isabel Bär
Tirsa van Duijl
Karin Fijnvandraat
Jeroen C. J. Eikenboom
Frank W. G. Leebeek
Ruben Bierings
Jan Voorberg
Despoina Trasanidou

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1719330

2,093 views

Perspective

Published on 03 Nov 2025

Proceedings of the second annual meeting of GenE-HumDi (COST Action 21113)

María Ortiz-Bueno
Iris Ramos-Hernández
Luis Algeciras-Jiménez
Nechama Kalter
Juan Roberto Rodríguez-Madoz
Jose Bonafont
Rajeevkumar Raveendran Nair
Oliver Feeney
Laura Torella
Lluis Montoliu

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1667329

1,381 views

Opinion

Published on 20 Oct 2025

Genome editing approaches to harness cytokinin–salicylic acid crosstalk for plant protection

Muhammad Naseem
Khalid Muhammad

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1687599

2,465 views

Editorial

Published on 20 Oct 2025

Editorial: Genome editing for climate change adaptation in agriculture: innovations, applications, and regulatory considerations

Koppolu Raja Rajesh Kumar
Prashant Kumar Singh

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1711767

3,502 views

Original Research

Published on 07 Oct 2025

CRISPR/Cas9- and Cas3-mediated modification of copy number variation in rice

Hyungjun Park
Takeshi Kuroha
Hiroaki Saika
Masaharu Kuroda
Hitoshi Yoshida

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1652950

2,435 views

Original Research

Published on 01 Oct 2025

From GWAS signal to function: targeted CRISPR activation enables functional characterization of non-coding SNPs in chickens

Jaewon Kim
Jeong Hoon Han
Minjun Kim
Grace Schmidt
Eunjin Cho
Jun Heon Lee
Tae Hyun Kim

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1662152

2,461 views

Original Research

Published on 29 Sep 2025

CRISPR-mediated generation of a tumor-associated antigen-deficient Raji platform to investigate antigen loss in CAR-T cell therapy

Aditya Ramdas Iyer
Mehwish Nafiz
Pragya Gupta
Arvinden VR
Vinodh Saravanakumar
Mohammad Sufyan Ansari
Md Shakir
Tanveer Ahmad
Sivaprakash Ramalingam

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1649993

2,805 views

Policy Brief

Published on 23 Sep 2025

Consumer choices regarding genome-edited food crops: lessons from Japan

Tetsuya Ishii

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1672358

2,191 views
1 citation

Editorial

Published on 22 Sep 2025

Editorial: Insights in genome editing in human health and disease 2023/2024

Baisong Lu
Haiwei Mou
Chen Liang

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1697828

3,130 views

Review

Published on 22 Sep 2025

Rewriting the script: gene therapy and genome editing for von Willebrand Disease

Alastair Barraclough
Isabel Bär
Tirsa van Duijl
Karin Fijnvandraat
Jeroen C. J. Eikenboom
Frank W. G. Leebeek
Ruben Bierings
Jan Voorberg
Despoina Trasanidou

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1620438

3,621 views
1 citation

Original Research

Published on 19 Sep 2025

Single-stranded DNA (ssDNA) donor repair templates and CRISPR/Cas9 enable a high-frequency of targeted insertions in potato

Matías N. González
Neha Salaria
Martin Friberg
Ying Liu
Josefin Alverup
Mariette Andersson
Per Hofvander

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1661829

2,968 views
1 citation

Mini Review

Published on 08 Sep 2025

CRISPR activation: identifying and using novel genes for plant disease resistance breeding

John E. McLaughlin
Idrice Carther Kue Foka
Michael A. Lawton
Rong Di

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1596600

5,325 views
1 citation

Mini Review

Published on 05 Sep 2025

In pursuit of an HIV cure: from stem cell transplants to gene therapies

Jennifer Clees
Maya Basic
Pedro E. Cruz
Servio H. Ramirez
Allison M. Andrews

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1634193

5,472 views

Original Research

Published on 04 Sep 2025

The decision to purchase genome edited food products by Iranian consumers: theory of planned behavior as a social intervention tool

Naser Valizadeh
Shobeir Karami

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1483510

1,614 views

Original Research

Published on 03 Sep 2025

Application of a multiplex CRISPR/Cas9 strategy for elimination of selection markers from transgenic plants

Mohammed Rafi
Mohamed ElSiddig
Maitha Aldarmaki
Mariam Al Nuaimi
Suja George
Khaled M. A. Amiri

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1633104

2,553 views

Brief Research Report

Published on 29 Aug 2025

Development of a homeolog-specific gene editing system in an evolutionary model for the study of polyploidy in nature

Shengchen Shan
Michael T. Pisias
Evgeny V. Mavrodiev
Jonathan P. Spoelhof
Bernard A. Hauser
W. Brad Barbazuk
Pamela S. Soltis
Douglas E. Soltis
Bing Yang

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1645542

2,189 views
1 citation

287 Publications

volumes

Volume 7 - 2025

Therapeutic applications of CRISPR-Cas9 gene editing

CRISPR/Cas9-Based Programmable Genome Editing in Chickens: Concepts, applications and regulatory issues

Development of efficient targeted insertion mediated by CRISPR-Cas12a and homology-directed repair in maize

Emerging tools in plant genome editing

CRISPR-Cas9 mediated editing of starch branching enzyme, SBE2 gene in potato for enhanced resistant starch for health benefits

Editorial: Social aspects of crop genome editing

Construction of EpCAM overexpression and knockdown vectors and their implications in colorectal cancer research

A long journey towards genome editing technologies in plants: a technical and critical review of genome editing technologies

Correction: Rewriting the script: gene therapy and genome editing for von Willebrand Disease

Proceedings of the second annual meeting of GenE-HumDi (COST Action 21113)

Genome editing approaches to harness cytokinin–salicylic acid crosstalk for plant protection

Editorial: Genome editing for climate change adaptation in agriculture: innovations, applications, and regulatory considerations

CRISPR/Cas9- and Cas3-mediated modification of copy number variation in rice

From GWAS signal to function: targeted CRISPR activation enables functional characterization of non-coding SNPs in chickens

CRISPR-mediated generation of a tumor-associated antigen-deficient Raji platform to investigate antigen loss in CAR-T cell therapy

Consumer choices regarding genome-edited food crops: lessons from Japan

Editorial: Insights in genome editing in human health and disease 2023/2024

Rewriting the script: gene therapy and genome editing for von Willebrand Disease

Single-stranded DNA (ssDNA) donor repair templates and CRISPR/Cas9 enable a high-frequency of targeted insertions in potato

CRISPR activation: identifying and using novel genes for plant disease resistance breeding

In pursuit of an HIV cure: from stem cell transplants to gene therapies

The decision to purchase genome edited food products by Iranian consumers: theory of planned behavior as a social intervention tool

Application of a multiplex CRISPR/Cas9 strategy for elimination of selection markers from transgenic plants

Development of a homeolog-specific gene editing system in an evolutionary model for the study of polyploidy in nature