volumes

Volume 3 - 2021

Brief Research Report

Published on 12 May 2021

CRISPR-Editing of Sweet Basil (Ocimum basilicum L.) Homoserine Kinase Gene for Improved Downy Mildew Disease Resistance

Xiaoyu Zhang
Yee Chen Low
Michael A. Lawton
James E. Simon
Rong Di

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.629769

6,687 views
20 citations

Original Research

Published on 12 May 2021

Efficient Targeted Mutagenesis Mediated by CRISPR-Cas12a Ribonucleoprotein Complexes in Maize

Shujie Dong
Yinping Lucy Qin
Christopher A. Vakulskas
Michael A. Collingwood
Mariam Marand
Stephen Rigoulot
Ling Zhu
Yaping Jiang
Weining Gu
Chunyang Fan

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.670529

9,684 views
26 citations

Original Research

Published on 29 Apr 2021

Multiallelic, Targeted Mutagenesis of Magnesium Chelatase With CRISPR/Cas9 Provides a Rapidly Scorable Phenotype in Highly Polyploid Sugarcane

Ayman Eid
Chakravarthi Mohan
Sara Sanchez
Duoduo Wang
Fredy Altpeter

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.654996

13,735 views
96 citations

Review

Published on 31 Mar 2021

Gene Editing of Hematopoietic Stem Cells: Hopes and Hurdles Toward Clinical Translation

Samuele Ferrari
Valentina Vavassori
Daniele Canarutto
Aurelien Jacob
Maria Carmina Castiello
Attya Omer Javed
Pietro Genovese

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.618378

19,874 views
44 citations

Review

Published on 24 Mar 2021

The Promise and the Hope of Gene Therapy

Eleni Papanikolaou
Andreas Bosio

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.618346

83,420 views
79 citations

Review

Published on 15 Mar 2021

Genome Editing in iPSC-Based Neural Systems: From Disease Models to Future Therapeutic Strategies

Amy McTague
Giada Rossignoli
Arianna Ferrini
Serena Barral
Manju A. Kurian

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.630600

26,635 views
51 citations

Brief Research Report

Published on 04 Mar 2021

Spelling Changes and Fluorescent Tagging With Prime Editing Vectors for Plants

Li Wang
Hilal Betul Kaya
Ning Zhang
Rhitu Rai
Matthew R. Willmann
Sara C. D. Carpenter
Andrew C. Read
Federico Martin
Zhangjun Fei
Jan E. Leach

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.617553

12,175 views
49 citations

Review

Published on 03 Mar 2021

Delivery Platforms for CRISPR/Cas9 Genome Editing of Glial Cells in the Central Nervous System

Vasco Meneghini
Marco Peviani
Marco Luciani
Giada Zambonini
Angela Gritti

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.644319

15,599 views
35 citations

Original Research

Published on 25 Feb 2021

Protein Phosphatase 2A Catalytic Subunit PP2A-1 Enhances Rice Resistance to Sheath Blight Disease

Qiu Jun Lin
Jin Chu
Vikranth Kumar
De Peng Yuan
Zhi Min Li
Qiong Mei
Yuan Hu Xuan

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.632136

4,767 views
17 citations

Original Research

Published on 09 Feb 2021

Baboon Envelope Pseudotyped “Nanoblades” Carrying Cas9/gRNA Complexes Allow Efficient Genome Editing in Human T, B, and CD34+ Cells and Knock-in of AAV6-Encoded Donor DNA in CD34+ Cells

Alejandra Gutierrez-Guerrero
Maria Jimena Abrey Recalde
Philippe E. Mangeot
Caroline Costa
Ornellie Bernadin
Séverine Périan
Floriane Fusil
Gisèle Froment
Adriana Martinez-Turtos
Adrien Krug

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.604371

22,972 views
45 citations

Mini Review

Published on 01 Feb 2021

Breaking Boundaries in the Brain—Advances in Editing Tools for Neurogenetic Disorders

Bronte A. Coorey
Wendy A. Gold

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.623519

4,425 views
4 citations

Review

Published on 28 Jan 2021

Base and Prime Editing Technologies for Blood Disorders

Panagiotis Antoniou
Annarita Miccio
Mégane Brusson

Frontiers in Genome Editing

doi 10.3389/fgeed.2021.618406

64,662 views
71 citations

Volume 2 - 2020

Review

Published on 04 Feb 2021

A Small Key for a Heavy Door: Genetic Therapies for the Treatment of Hemoglobinopathies

Hidde A. Zittersteijn
Cornelis L. Harteveld
Stefanie Klaver-Flores
Arjan C. Lankester
Rob C. Hoeben
Frank J. T. Staal
Manuel A. F. V. Gonçalves

Frontiers in Genome Editing

doi 10.3389/fgeed.2020.617780

10,934 views
18 citations

Review

Published on 28 Jan 2021

Using Synthetically Engineered Guide RNAs to Enhance CRISPR Genome Editing Systems in Mammalian Cells

Daniel Allen
Michael Rosenberg
Ayal Hendel

Frontiers in Genome Editing

doi 10.3389/fgeed.2020.617910

49,772 views
81 citations

Review

Published on 22 Jan 2021

Genomic Engineering in Human Hematopoietic Stem Cells: Hype or Hope?

Stefanie Klaver-Flores
Hidde A. Zittersteijn
Kirsten Canté-Barrett
Arjan Lankester
Rob C. Hoeben
Manuel A. F. V. Gonçalves
Karin Pike-Overzet
Frank J. T. Staal

Frontiers in Genome Editing

doi 10.3389/fgeed.2020.615619

8,996 views
9 citations

Review

Published on 22 Jan 2021

Mesenchymal Stromal Cells as a Cellular Target in Myeloid Malignancy: Chances and Challenges in the Genome Editing of Stromal Alterations

Bella Banjanin
Rebekka K. Schneider

Frontiers in Genome Editing

doi 10.3389/fgeed.2020.618308

4,299 views
5 citations

Original Research

Published on 21 Jan 2021

Genome Editing and Protoplast Regeneration to Study Plant–Pathogen Interactions in the Model Plant Nicotiana benthamiana

Chen-Tran Hsu
Wen-Chi Lee
Yu-Jung Cheng
Yu-Hsuan Yuan
Fu-Hui Wu
Choun-Sea Lin

Frontiers in Genome Editing

doi 10.3389/fgeed.2020.627803

14,129 views
29 citations

Mini Review

Published on 20 Jan 2021

Targeted Gene Delivery: Where to Land

Giulia Pavani
Mario Amendola

Frontiers in Genome Editing

doi 10.3389/fgeed.2020.609650

23,808 views
39 citations

Original Research

Published on 20 Jan 2021

Fast-TrACC: A Rapid Method for Delivering and Testing Gene Editing Reagents in Somatic Plant Cells

Ryan A. Nasti
Matthew H. Zinselmeier
Macy Vollbrecht
Michael F. Maher
Daniel F. Voytas

Frontiers in Genome Editing

doi 10.3389/fgeed.2020.621710

11,839 views
13 citations

Original Research

Published on 12 Jan 2021

Precise Genome Editing in miRNA Target Site via Gene Targeting and Subsequent Single-Strand-Annealing-Mediated Excision of the Marker Gene in Plants

Namie Ohtsuki
Keiko Kizawa
Akiko Mori
Ayako Nishizawa-Yokoi
Takao Komatsuda
Hitoshi Yoshida
Katsuyuki Hayakawa
Seiichi Toki
Hiroaki Saika

Frontiers in Genome Editing

doi 10.3389/fgeed.2020.617713

5,719 views
7 citations

Review

Published on 12 Jan 2021

Non-immunogenic Induced Pluripotent Stem Cells, a Promising Way Forward for Allogenic Transplantations for Neurological Disorders

Henriette Reventlow Frederiksen
Ulrik Doehn
Pernille Tveden-Nyborg
Kristine K. Freude

Frontiers in Genome Editing

doi 10.3389/fgeed.2020.623717

9,915 views
17 citations

Original Research

Published on 11 Jan 2021

Development of a Transformable Fast-Flowering Mini-Maize as a Tool for Maize Gene Editing

Morgan E. McCaw
Keunsub Lee
Minjeong Kang
Jacob D. Zobrist
Mercy K. Azanu
James A. Birchler
Kan Wang

Frontiers in Genome Editing

doi 10.3389/fgeed.2020.622227

12,861 views
20 citations

Review

Published on 08 Jan 2021

CRISPR-Based Genetic Manipulation of Candida Species: Historical Perspectives and Current Approaches

Deeva Uthayakumar
Jehoshua Sharma
Lauren Wensing
Rebecca S. Shapiro

Frontiers in Genome Editing

doi 10.3389/fgeed.2020.606281

19,425 views
46 citations

Original Research

Published on 23 Dec 2020

CRISPR-Cas9-Mediated Mutagenesis of the Rubisco Small Subunit Family in Nicotiana tabacum

Sophie Donovan
Yuwei Mao
Douglas J. Orr
Elizabete Carmo-Silva
Alistair J. McCormick

Frontiers in Genome Editing

doi 10.3389/fgeed.2020.605614

11,785 views
37 citations