Frontiers in Genome Editing

Original Research

Published on 12 Jan 2023

Whole genome sequencing of CCR5 CRISPR-Cas9-edited Mauritian cynomolgus macaque blastomeres reveals large-scale deletions and off-target edits

Jenna Kropp Schmidt
Yun Hee Kim
Nick Strelchenko
Sarah R. Gierczic
Derek Pavelec
Thaddeus G. Golos
Igor I. Slukvin

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1031275

4,897 views
3 citations

Mini Review

Published on 11 Jan 2023

Genome editing approaches using reproductive cells/tissues in flowering plants

Erika Toda
Norio Kato
Tetsuya Higashiyama
Takashi Okamoto

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1085023

5,215 views
9 citations

Policy and Practice Reviews

Published on 10 Jan 2023

Are null segregants new combinations of heritable material and should they be regulated?

Jack A. Heinemann
Katrin Clark
Tessa C. Hiscox
Andrew W. McCabe
Sarah Z. Agapito-Tenfen

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1064103

6,752 views
5 citations

Review

Published on 09 Jan 2023

Hematopoietic stem and progenitors cells gene editing: Beyond blood disorders

Valentina Buffa
José Roberto Alvarez Vargas
Anne Galy
Simone Spinozzi
Céline J. Rocca

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.997142

10,135 views
9 citations

Mini Review

Published on 06 Jan 2023

CRISPR medicine for blood disorders: Progress and challenges in delivery

Tahereh Mohammadian Gol
Guillermo Ureña-Bailén
Yujuan Hou
Ralph Sinn
Justin S. Antony
Rupert Handgretinger
Markus Mezger

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1037290

9,743 views
13 citations

Original Research

Published on 23 Dec 2022

Efficient hyperactive piggyBac transgenesis in Plodia pantry moths

Christa Heryanto
Anyi Mazo-Vargas
Arnaud Martin

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1074888

5,168 views
14 citations

Original Research

Published on 20 Dec 2022

Efficient and error-free correction of sickle mutation in human erythroid cells using prime editor-2

Anila George
Nithin Sam Ravi
Kirti Prasad
Lokesh Panigrahi
Sanya Koikkara
Vignesh Rajendiran
Nivedhitha Devaraju
Joshua Paul
Aswin Anand Pai
Yukio Nakamura

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1085111

7,526 views
3 citations

Review

Published on 08 Dec 2022

Imaging tools for plant nanobiotechnology

Bin Zhao
Zhongxu Luo
Honglu Zhang
Huan Zhang

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1029944

7,038 views
22 citations

Review

Published on 10 Nov 2022

CRISPR nuclease off-target activity and mitigation strategies

Beeke Wienert
M. Kyle Cromer

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1050507

15,698 views
42 citations

Review

Published on 02 Nov 2022

Nanoparticles targeting hematopoietic stem and progenitor cells: Multimodal carriers for the treatment of hematological diseases

Luis J. Cruz
Somayeh Rezaei
Frank Grosveld
Sjaak Philipsen
Christina Eich

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1030285

13,488 views
21 citations

Review

Published on 14 Oct 2022

Plant biomacromolecule delivery methods in the 21st century

Sachin Rustgi
Salman Naveed
Jonathan Windham
Huan Zhang
Gözde S. Demirer

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.1011934

10,062 views
25 citations

Original Research

Published on 06 Oct 2022

Environmental and socio-economic impacts of new plant breeding technologies: A case study of root chicory for inulin production

Maria Hingsamer
Veronika Kulmer
Matthew de Roode
Michael Kernitzkyi

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.919392

12,024 views
13 citations

Original Research

Published on 27 Sep 2022

In vivo and in vitro genome editing to explore GNE functions

Nili Ilouz
Avi Harazi
Miriam Guttman
Alon Daya
Shmuel Ruppo
Lena Yakovlev
Stella Mitrani-Rosenbaum

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.930110

6,467 views
12 citations

Mini Review

Published on 07 Sep 2022

CRISPR/Cas genome editing improves abiotic and biotic stress tolerance of crops

Yangyang Li
Xiuzhe Wu
Yan Zhang
Qiang Zhang

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.987817

18,789 views
64 citations

Original Research

Published on 06 Sep 2022

Agrobacterium- and a single Cas9-sgRNA transcript system-mediated high efficiency gene editing in perennial ryegrass

Rahul Kumar
Troy Kamuda
Roshani Budhathoki
Dan Tang
Huseyin Yer
Yunde Zhao
Yi Li

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.960414

7,225 views
17 citations

Review

Published on 31 Aug 2022

Towards social acceptability of genome-edited plants in industrialised countries? Emerging evidence from Europe, United States, Canada, Australia, New Zealand, and Japan

Armin Spök
Thorben Sprink
Andrew C. Allan
Tomiko Yamaguchi
Christian Dayé

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.899331

14,848 views
43 citations

Review

Published on 31 Aug 2022

Bacterial genome reductions: Tools, applications, and challenges

Nicole LeBlanc
Trevor C. Charles

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.957289

10,545 views
32 citations

Review

Published on 22 Aug 2022

Natural and artificial sources of genetic variation used in crop breeding: A baseline comparator for genome editing

Jorge Martínez-Fortún
Dylan W. Phillips
Huw D. Jones

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.937853

11,541 views
23 citations

Correction

Published on 04 Aug 2022

Corrigendum: Strategies for Efficient Gene Editing in Protoplasts of Solanum tuberosum Theme: Determining gRNA Efficiency Design by Utilizing Protoplast (Research)

Frida Meijer Carlsen
Ida Elisabeth Johansen
Zhang Yang
Ying Liu
Ida Nøhr Westberg
Nam Phuong Kieu
Bodil Jørgensen
Marit Lenman
Erik Andreasson
Kåre Lehmann Nielsen

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.914100

1,978 views
2 citations

Brief Research Report

Published on 26 Jul 2022

The trans DNA cleavage activity of Cas12a provides no detectable immunity against plasmid or phage

Shunhang Liu
Xichen Rao
Ruiliang Zhao
Wenyuan Han

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.929929

4,207 views
9 citations

Review

Published on 26 Jul 2022

Improvements of nuclease and nickase gene modification techniques for the treatment of genetic diseases

Yaoyao Lu
Cedric Happi Mbakam
Bo Song
Eli Bendavid
Jacques-P. Tremblay

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.892769

9,491 views
15 citations

Field Grand Challenge

Published on 15 Jul 2022

The promise of gene editing: so close and yet so perilously far

David J. Segal

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.974798

6,743 views
8 citations

Review

Published on 15 Jul 2022

Gene Editing to Tackle Facioscapulohumeral Muscular Dystrophy

Virginie Mariot
Julie Dumonceaux

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.937879

8,196 views
14 citations

Original Research

Published on 14 Jul 2022

Examination of the Cell Cycle Dependence of Cytosine and Adenine Base Editors

Cameron A. Burnett
Ashley T. Wong
Carlos A. Vasquez
Colleen A. McHugh
Gene W. Yeo
Alexis C. Komor

Frontiers in Genome Editing

doi 10.3389/fgeed.2022.923718

7,017 views
9 citations

287 Publications

volumes

Volume 4 - 2022

Whole genome sequencing of CCR5 CRISPR-Cas9-edited Mauritian cynomolgus macaque blastomeres reveals large-scale deletions and off-target edits

Genome editing approaches using reproductive cells/tissues in flowering plants

Are null segregants new combinations of heritable material and should they be regulated?

Hematopoietic stem and progenitors cells gene editing: Beyond blood disorders

CRISPR medicine for blood disorders: Progress and challenges in delivery

Efficient hyperactive piggyBac transgenesis in Plodia pantry moths

Efficient and error-free correction of sickle mutation in human erythroid cells using prime editor-2

Imaging tools for plant nanobiotechnology

CRISPR nuclease off-target activity and mitigation strategies

Nanoparticles targeting hematopoietic stem and progenitor cells: Multimodal carriers for the treatment of hematological diseases

Plant biomacromolecule delivery methods in the 21st century

Environmental and socio-economic impacts of new plant breeding technologies: A case study of root chicory for inulin production

In vivo and in vitro genome editing to explore GNE functions

CRISPR/Cas genome editing improves abiotic and biotic stress tolerance of crops

Agrobacterium- and a single Cas9-sgRNA transcript system-mediated high efficiency gene editing in perennial ryegrass

Towards social acceptability of genome-edited plants in industrialised countries? Emerging evidence from Europe, United States, Canada, Australia, New Zealand, and Japan

Bacterial genome reductions: Tools, applications, and challenges

Natural and artificial sources of genetic variation used in crop breeding: A baseline comparator for genome editing

Corrigendum: Strategies for Efficient Gene Editing in Protoplasts of Solanum tuberosum Theme: Determining gRNA Efficiency Design by Utilizing Protoplast (Research)

The trans DNA cleavage activity of Cas12a provides no detectable immunity against plasmid or phage

Improvements of nuclease and nickase gene modification techniques for the treatment of genetic diseases

The promise of gene editing: so close and yet so perilously far

Gene Editing to Tackle Facioscapulohumeral Muscular Dystrophy

Examination of the Cell Cycle Dependence of Cytosine and Adenine Base Editors