Frontiers in Immunology

Perspective

Published on 16 Feb 2026

Chrono-immunotherapy’s current and future optimization strategies: immunotherapy timing in line with the circadian rhythm brings longer survival benefits

in Cancer Immunity and Immunotherapy

Daiwei Liu
Zhanlin Li
Huijuan Cui
Hua Zhang
Hai Li
Xiaoyuan Wu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1777437

188 views

Original Research

Published on 16 Feb 2026

APOs as promising prognostic biomarkers: correlation with tumor-infiltrating leukocytes in endometrial cancer

in Cancer Immunity and Immunotherapy

Lina Zhou
Rencheng Wang
Guiqiang Du
Yupeng Wu
Hui Li
Yinyan He
Zhikang Ye
Jiangdong Xiang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1646920

350 views

Original Research

Published on 16 Feb 2026

Platelet-rich plasma-derived microRNA let-7a-5p alleviates knee osteoarthritis by regulating macrophage polarization and improving inflammatory microenvironment

in Inflammation

Qishan Li
Mengjie Wang
Dong Wang
Yaochi Nie
Xueyuan Sun
Lin Na
Dongmei Yan
Yuhang Ma
Hui Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1756467

274 views

Review

Published on 16 Feb 2026

The spatial architecture of neuroimmune interactions in epilepsy

in Inflammation

Dianwu Chu
Wuhao Zhang
Xing Zhou
Hang Yin
Jian Yin

Frontiers in Immunology

doi 10.3389/fimmu.2026.1742927

194 views

Original Research

Published on 16 Feb 2026

From dysbiosis to prediction: a novel gut microbiota–derived index for spontaneous bacterial peritonitis in HBV-related cirrhosis

in Microbial Immunology

Zhewen Zhou
Xiu Sun
Danying Cheng
Huichun Xing

Frontiers in Immunology

doi 10.3389/fimmu.2026.1753063

221 views

Case Report

Published on 16 Feb 2026

Recurrent anti-TIF1γ-positive dermatomyositis coexisting with postoperative parotid lymphoepithelial carcinoma: a case report with pathogenesis analysis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Xiaoguang Cui
Kaihong Ye
Hong Wang
Yali Kang
Junqiao Feng
Yameng Wei
Nan Xu
Fuqian Lei
Shan Wang
Rick F. Thorne

Frontiers in Immunology

doi 10.3389/fimmu.2026.1748650

154 views

Case Report

Published on 16 Feb 2026

Pulmonary light chain deposition disease secondary to Sjögren disease: a case report

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Xiaotong Xu
Lingjian Wang
Chunsheng Zhou
Lu Zhang
Ting Zhang
Min Peng
Rui’e Feng
Juhong Shi

Frontiers in Immunology

doi 10.3389/fimmu.2026.1747455

155 views

Original Research

Published on 16 Feb 2026

miRNA expression profile as a potential tool for discrimination between bacterial and interstitial cystitis

in Inflammation

Dominika Peskar
Nika Kojc
Andreja Erman
Emanuela Boštjančič

Frontiers in Immunology

doi 10.3389/fimmu.2026.1738839

223 views

Review

Published on 16 Feb 2026

The crosstalk between nerves and immunity: chronic stress as a driver of tumor progression

in Cancer Immunity and Immunotherapy

Yuan He
Haoliang Yu
Fengze Li
Junzhe Liu
Zhihao Chen
Wenping Zhu
Li Yang
Tengfeng Yan

Frontiers in Immunology

doi 10.3389/fimmu.2026.1758894

208 views

Correction

Published on 16 Feb 2026

Correction: Immune checkpoint inhibitor-related Stevens-Johnson syndrome and toxic epidermal necrolysis: a retrospective analysis of 21 cases

in Cancer Immunity and Immunotherapy

Tianshu Pu
Yaru Teng
Yuezhu Zhang
Meihong Da
Fei Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1804871

Case Report

Published on 16 Feb 2026

Treatment of Kimura disease with dupilumab: a case report and literature review

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Wei Yang
Ze Wu
Jun Niu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1670489

140 views

Original Research

Published on 16 Feb 2026

Pre-existing activation states shape functional heterogeneity of human Vγ9Vδ2 T cells

in Cancer Immunity and Immunotherapy

Anna Vyborova
Laia Gasull-Celades
Peter Brazda
Alberto Miranda Bedate
Froso Karaiskaki
Jasper Sanders
Anke Janssen
Trudy Straetemans
Dennis X. Beringer
Zsolt Sebestyen

Frontiers in Immunology

doi 10.3389/fimmu.2026.1696469

326 views

Original Research

Accepted on 14 Feb 2026

Immune-related adverse events in patients with preexisting myasthenia gravis and thymoma following immune checkpoint inhibitor treatment: A retrospective, observational study

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Chao Sun
Guo Rongjing
Xunliang Yin
Feng Lanlan
Yize Guo
Yueliang Xu
Sijia Hao
Xiaoxi Huang
Na Song
Ting Gao

Frontiers in Immunology

396 views

Original Research

Accepted on 14 Feb 2026

Racial Disparities in Ankylosing Spondylitis Risk Following Tonsillectomy: A Large-Scale Retrospective Analysis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Jiafeng Zhang
Yadong Chu
Yufeng Zhu
Huang Hua Bing
Chien Han Tsao
Yu Hsun Wang
Jame Cheng-Chun Wei

Frontiers in Immunology

320 views

Mini Review

Accepted on 13 Feb 2026

Regulation of B cell Development and Lymphocyte Function by Transcription Coactivator OCA-B

in B Cell Biology

Robert Roeder
Xiangdong Lu

Frontiers in Immunology

357 views

Original Research

Accepted on 13 Feb 2026

The Role of Large Immune Complexes in Anti-drug Antibody Development: A Case Study of Anti-SARS-CoV-2 Antibody Therapeutics and Co-administered mRNA vaccine

in Vaccines and Molecular Therapeutics

Susan C. Irvin
Zhiqiang Wang
Samit Ganguly
Deepanshu Choudhary
Minita Kanagaraj
Nina Liu
Flonza Isa
Zhongqing Will He
Hong Yan
Veronica Mas Casullo

Frontiers in Immunology

410 views

Original Research

Accepted on 13 Feb 2026

The Nrf2-SLPI Axis in Aging and Its Role in the Pathophysiology of Pulmonary Mycobacterium avium Complex Disease

in Microbial Immunology

Sosuke Matsumura
Masashi Matsuyama
Masayuki Nakajima
Chio Sakai
Kodai Ueda
Mizu Nonaka
KENGO NISHINO
Zhenting Wei
Yuki Yabuuchi
Kenya Kuramoto

Frontiers in Immunology

408 views

Original Research

Accepted on 13 Feb 2026

Hemophagocytic Lymphohistiocytosis Directly Triggered by Peginterferon Alfa-2b in a Patient with Chronic Hepatitis B

in Cytokines and Soluble Mediators in Immunity

Peipei Wang
Jiahui Pang
Huiming Xu
Menglan Wang
Wenxing Lai
Dayang Hui
Qingxian Cai
Xudong Li
Jianyun Zhu

Frontiers in Immunology

344 views

Original Research

Accepted on 13 Feb 2026

Nomogram Model for Predicting Incomplete Immune Reconstitution in People Living with HIV Based on Clinical Characteristics

in Viral Immunology

Yaqiong Zhang
Wenjia Hu
Xiaoxia Zhang
Yulin Zhang
Zhongwei Zhang
Qunqun Jiang
Shan Wang
Yong Nan
Shihui Song
Yong Xiong

Frontiers in Immunology

Original Research

Accepted on 13 Feb 2026

Immunoreactivity of Pan MHC-I Epitopes on Crimean-Congo Hemorrhagic Fever Virus Glycoprotein C-terminal

in Viral Immunology

Dongbo Jiang
YK Wang
Haobo Kang
Zhenchi Fang
Jianchang Li
Zilu Ma
Yubo Sun
Yanbo Wang
Zhihe Fu
Yulin Yang

Frontiers in Immunology

118 views

Systematic Review

Accepted on 13 Feb 2026

Neoadjuvant Chemoradiotherapy With or Without PD-1 Inhibitors in MMR‑Proficient Non‑Metastatic Rectal Cancer: A Meta-Analysis of Randomized Controlled Trials

in Cancer Immunity and Immunotherapy

Yuegang Li
Chengcheng Han
Jianqiang Tang

Frontiers in Immunology

Brief Research Report

Accepted on 13 Feb 2026

The natural human adaptive IgG-specific immune response is skewed towards nonprotective tail domains of DNABII proteins

in Microbial Immunology

Kathryn Q. Wilbanks
Jaime D. Rhodes
Steven D Goodman
Sanjay Sethi
Timothy Murphy
Lauren O Bakaletz

Frontiers in Immunology

Original Research

Accepted on 13 Feb 2026

Targeting neuroinflammation: itaconate and mesaconate as therapeutic strategies against H7N7 influenza-associated CNS damage

in Cytokines and Soluble Mediators in Immunity

Melanie Ohm
Wei He
Dunja Bruder
Karsten Hiller
Martin Korte
Shirin Hosseini

Frontiers in Immunology

Original Research

Accepted on 13 Feb 2026

Automated manufacturing of clinical-grade BDCA2 CAR NK cells in a closed system for the treatment of blastic plasmacytoid dendritic cell neoplasm

in NK and Innate Lymphoid Cell Biology

Rita Pfeifer
Sabine Müller
Marcus Nitsche
Melanie Sohmen
Julia Kostyra
Arthur Bister
Cathrin Bleilevens
Janina Brauner
Angela Mekes
Juliane Raasch

Frontiers in Immunology

49,912 articles

articles

Chrono-immunotherapy’s current and future optimization strategies: immunotherapy timing in line with the circadian rhythm brings longer survival benefits

APOs as promising prognostic biomarkers: correlation with tumor-infiltrating leukocytes in endometrial cancer

Platelet-rich plasma-derived microRNA let-7a-5p alleviates knee osteoarthritis by regulating macrophage polarization and improving inflammatory microenvironment

The spatial architecture of neuroimmune interactions in epilepsy

From dysbiosis to prediction: a novel gut microbiota–derived index for spontaneous bacterial peritonitis in HBV-related cirrhosis

Recurrent anti-TIF1γ-positive dermatomyositis coexisting with postoperative parotid lymphoepithelial carcinoma: a case report with pathogenesis analysis

Pulmonary light chain deposition disease secondary to Sjögren disease: a case report

miRNA expression profile as a potential tool for discrimination between bacterial and interstitial cystitis

The crosstalk between nerves and immunity: chronic stress as a driver of tumor progression

Correction: Immune checkpoint inhibitor-related Stevens-Johnson syndrome and toxic epidermal necrolysis: a retrospective analysis of 21 cases

Treatment of Kimura disease with dupilumab: a case report and literature review

Pre-existing activation states shape functional heterogeneity of human Vγ9Vδ2 T cells

Immune-related adverse events in patients with preexisting myasthenia gravis and thymoma following immune checkpoint inhibitor treatment: A retrospective, observational study

Racial Disparities in Ankylosing Spondylitis Risk Following Tonsillectomy: A Large-Scale Retrospective Analysis

Regulation of B cell Development and Lymphocyte Function by Transcription Coactivator OCA-B

The Role of Large Immune Complexes in Anti-drug Antibody Development: A Case Study of Anti-SARS-CoV-2 Antibody Therapeutics and Co-administered mRNA vaccine

The Nrf2-SLPI Axis in Aging and Its Role in the Pathophysiology of Pulmonary Mycobacterium avium Complex Disease

Hemophagocytic Lymphohistiocytosis Directly Triggered by Peginterferon Alfa-2b in a Patient with Chronic Hepatitis B

Nomogram Model for Predicting Incomplete Immune Reconstitution in People Living with HIV Based on Clinical Characteristics

Immunoreactivity of Pan MHC-I Epitopes on Crimean-Congo Hemorrhagic Fever Virus Glycoprotein C-terminal

Neoadjuvant Chemoradiotherapy With or Without PD-1 Inhibitors in MMR‑Proficient Non‑Metastatic Rectal Cancer: A Meta-Analysis of Randomized Controlled Trials

The natural human adaptive IgG-specific immune response is skewed towards nonprotective tail domains of DNABII proteins

Targeting neuroinflammation: itaconate and mesaconate as therapeutic strategies against H7N7 influenza-associated CNS damage

Automated manufacturing of clinical-grade BDCA2 CAR NK cells in a closed system for the treatment of blastic plasmacytoid dendritic cell neoplasm