Frontiers in Immunology

Original Research

Accepted on 30 Jun 2025

Integrated multi-omics and machine learning reveal an immunogenic cell death-related signature for prognostic stratification and therapeutic optimization in colorectal cancer

in Cancer Immunity and Immunotherapy

Siyu Hou
Shanshan Heng
Shaozhuo Xie
Yuanchun Zhao
Jiajia Chen
Chunjiang Yu
Yuxin Lin
Xin Qi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1606874

194 views

Original Research

Accepted on 30 Jun 2025

Engineered Human B Cells Targeting Tumor-Associated Antigens Exhibit Antigen Presentation and Antibody-Mediated Functions

in B Cell Biology

Alexander Boucher
Courtney Anderson
Rochelle Hinman
Molly Kindschuh
Jeremy Fung
Tiansu Wang
Isabella Klooster
Elise Kim
Caroline Roth
Michael Vander Oever

Frontiers in Immunology

doi 10.3389/fimmu.2025.1621222

125 views

Review

Accepted on 30 Jun 2025

Harnessing Immunotherapy: Cancer Vaccines as Novel Therapeutic Strategies for Brain Tumor

in Cancer Immunity and Immunotherapy

Klaudia Kiel
Raziye Piranlioglu
Jakub Godlewski
Agnieszka Bronisz

Frontiers in Immunology

doi 10.3389/fimmu.2025.1588081

181 views

Review

Accepted on 30 Jun 2025

Immunomodulatory Actions of Tonifying Polysaccharides: Pharmacological Effects, Mechanisms and Therapeutic Applications

in Molecular Innate Immunity

Jinyu Li
Chang Yi
Mengqin Zhu
Yanfeng Yuan
Guang Chen
Ningning Qiu
Lei Shen
Liya Song
Xili Zhang
Wenlong Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1640679

Review

Accepted on 30 Jun 2025

Clinical Application Prospects of Traditional Chinese Medicine as Adjuvant Therapy for Metabolic Reprogramming in Colorectal Cancer

in Cancer Immunity and Immunotherapy

Zhexian Liu
Xingqi Guo
Xinxin Dong
Tong Xia
Siping Ma
Yanxi Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1630279

110 views

Review

Accepted on 30 Jun 2025

Cytokines Unveiled: Their Impact on Oral and Multisystem Features of Lupus Erythematosus

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Noha Mousaad Elemam
Iman Mamdouh Talaat
Omar El Meligy

Frontiers in Immunology

doi 10.3389/fimmu.2025.1585280

106 views

Review

Accepted on 30 Jun 2025

Deciphering the Mechanistic Roles of ADARs in Cancer Pathogenesis, Tumor Immune Evasion, and Drug Resistance

in Cancer Immunity and Immunotherapy

Yangfang He
Fei Yin
Yue Qiao
Yan Yan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1621585

Review

Accepted on 30 Jun 2025

Effects of Choline Metabolite-Trimethylamine N-oxide on Immunometabolism in Inflammatory Bowel Disease

in Microbial Immunology

Siyu Wang
Yifan Ni
Shuwei Zhou
Huiping Peng
Ying Cao
Yue Zhu
Jing Gong
Qiulu Lu
Zhongyu Han
Yumeng Lin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1591151

Review

Accepted on 30 Jun 2025

Ferroptosis and Bone Health: Bridging the Gap Between Mechanisms and Therapy

in Inflammation

Renyan Xiao
Zhongyu Han
Peng Jia
Pei Li
Meng Gong
Cai yijin
Lina Pang
Xiangyin Ye
Song Jin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1634516

Original Research

Accepted on 30 Jun 2025

Liver metastases in thyroid cancer: epidemiology, risk stratification and survival Outcomes in the immunotherapy era

in Cancer Immunity and Immunotherapy

Ming-Lu Xu
Yang-Yang Wang
Li-Ping Xie
Ning Ding
Jia-Jun Hui

Frontiers in Immunology

doi 10.3389/fimmu.2025.1624181

108 views

Original Research

Accepted on 30 Jun 2025

Autonomic Nervous System Development-Related Signature as Novel Predictive Biomarkers for Immunotherapy in Pan-Cancers

in Cancer Immunity and Immunotherapy

Cunen Wu
Weiwei Xue
Yuwen Zhuang
Dayue Darrel Dayue
Zhou Zhou
Xiaoxiao Wang
Zhenfeng Wu
Jin-Yong Zhou
Xiangkun Huan
Ruiping Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1611890

127 views

Case Report

Accepted on 30 Jun 2025

Lymphoepithelioma-like Carcinoma with Carcinosarcoma of the Endometrium: A Case Report and Literature Review

in Cancer Immunity and Immunotherapy

Jialing Xu
Bin Huang
Yanhua Zhu
Jianping Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1636575

Original Research

Accepted on 30 Jun 2025

Reduced Tolerogenic Factor sCD83 in NMOSD and Relapsing MOGAD: A Potential New Therapeutic Pathway

in Multiple Sclerosis and Neuroimmunology

Ariel Rechtman
Omri Zveik
Lyne Shweiki
garrick Hoichman
Tal Friedman-korn
Livnat Brill
ADI Vaknin-Dembinsky

Frontiers in Immunology

doi 10.3389/fimmu.2025.1620069

100 views

Case Report

Accepted on 30 Jun 2025

Early immunotherapy in a patient with myelin oligodendrocyte glycoprotein antibody-associated disease with syphilis and acquired immune deficiency syndrome: A case report

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Qiuxia Zhang
Lin-Jie Zhang
Bin Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1591365

115 views

Original Research

Accepted on 30 Jun 2025

Advanced immunophenotyping of lymphocyte and monocyte subsets in healthy Australian adults using a novel spectral flow cytometry panel

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Ainsley R Davies
Kristy Kwong
Zhijia Yu
Koula EM Diamand
Fei-Ju Li
Citha Kannitha
Sidra A Ali
Abolfazl Amjadipour
Ann-Maree Padarin
Michael Devoy

Frontiers in Immunology

doi 10.3389/fimmu.2025.1577206

173 views

Original Research

Accepted on 30 Jun 2025

NK Cell-Derived Extracellular Vesicles Enhance Cytotoxicity and Immune Cell Recruitment in Non-Small Cell Lung Cancer

in Cancer Immunity and Immunotherapy

Joanna Palade
Eric Alsop
Nanyun Tang
Jerry Antone
Dorothy M Paredes
Tithi Ghosh Halder
Raffaella Soldi
Taylor Bargenquast
Gary Schwartz
Jennifer Finholt

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633010

107 views