Frontiers in Immunology

Brief Research Report

Published on 11 Dec 2025

IL-33 and IL-3 synergistically induce CD25 expression on human basophils without functional IL-2 signaling: a potential marker of severe COVID-19

in Molecular Innate Immunity

Sruthi Vijaya Retnakumar
Suraj Chandrabhan Singh
Camille Chauvin
Jagadeesh Bayry

Frontiers in Immunology

doi 10.3389/fimmu.2025.1718240

767 views

Original Research

Published on 11 Dec 2025

The contribution of amphibian macrophage subsets to scarless regeneration of skin wounds

in Comparative Immunology

Christina N. Garvey Griffith
Kelsey A. Hauser
Bradley Abramson
Elissa R. Chapkin
Elizabeth J. Jones
Anju N. Duttargi
Leon Grayfer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1713361

722 views

Original Research

Published on 11 Dec 2025

Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation

in Inflammation

Linling Du
Jie Pan
Nan Xu
Feng Yan
Weiyi Tian
Qiyan Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1705047

866 views

Review

Published on 11 Dec 2025

Brain TRPV1 channel-mediated calcium influx: the immunomodulatory pathway of acupuncture in neuroinflammation

in Multiple Sclerosis and Neuroimmunology

Qingqing Tang
Min He
Peng Zheng
Mengmeng Sun
Jiazhen Cao
Qi Zhang
Jing He
Run Sun
Bing Zhu
Tie Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1700282

908 views

Original Research

Published on 11 Dec 2025

Glymphatic dysfunction in neuromyelitis optica spectrum disorder

in Multiple Sclerosis and Neuroimmunology

Ying Zhang
Hongxi Chen
Ziyan Shi
Rui Wang
Xiaofei Wang
Qin Du
Yuntao Mo
Shixiang Chen
Hongyu Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1698986

884 views

Correction

Published on 11 Dec 2025

Correction: GATA2 deficiency in an adult with alveolar proteinosis, infections, lymphadenopathy with granulomatosis, and immune deficiency: case report

in Primary Immunodeficiencies

Juliana Gabzdilová
Štefan Raffáč
Gabriela Krasňanská
Michal Konečný

Frontiers in Immunology

doi 10.3389/fimmu.2025.1750971

271 views

Original Research

Published on 11 Dec 2025

Prognostic significance of reduced handgrip strength in patients with unresectable hepatocellular carcinoma receiving HAIC combined with targeted immunotherapy

in Cancer Immunity and Immunotherapy

Xin-Ze Wang
Ping Wang
Xing Lv
Zi-Long Zhang
Er-Lei Zhang
Gui-Bao Ji

Frontiers in Immunology

doi 10.3389/fimmu.2025.1672519

471 views

Review

Published on 11 Dec 2025

The role of nucleic acid sensors in antifungal immunity

in Microbial Immunology

Xinyu Liang
Hui Zhou
Litong Ouyang
Jiming Chen
Wenji He

Frontiers in Immunology

doi 10.3389/fimmu.2025.1725717

580 views

Original Research

Published on 11 Dec 2025

Identification of serum MicroRNAs associated with hepatic immunoinflammatory injury in chronic hepatitis B: implications for non-invasive diagnosis

in Molecular Innate Immunity

Mengkui Han
Junchi Xu
Xunxun Wu
Zhiqing Hu
Xiaoyuan Hu
Xiaolong Zhu
Cailin Chen
Qinkao Xuan
Yang Li
Chuanwu Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1671149

714 views

Original Research

Published on 11 Dec 2025

Vinegar intake in patients undergoing immune checkpoint inhibitor therapy: food frequency questionnaire study

in Cancer Immunity and Immunotherapy

Hirotsugu Ariizumi
Miyuki Shimazui
Chisato Ogawa
Mika Kaneki
Nanaho Saito
Emiko Mura
Risako Suzuki
Toshiaki Tsurui
Nana Iriguchi
Tomoyuki Ishiguro

Frontiers in Immunology

doi 10.3389/fimmu.2025.1640603

790 views

Review

Published on 11 Dec 2025

Beneficial effects of food-medicine homologous herbs for patients with diabetic kidney disease

in Nutritional Immunology

Qin Zeng
Wenru Wang
Yihan Li
Ming Wang
Zhengtang Liu
Lei Yan
Jingyi Zhan
Xinhui Wang
Ying Liang
Renhuan Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1698240

886 views

Mini Review

Published on 11 Dec 2025

Intrathecal rituximab for the treatment of Epstein–Barr virus-associated encephalitis

in Viral Immunology

Aude G. Chapuis
Johnnie J. Orozco
Filippo Milano

Frontiers in Immunology

doi 10.3389/fimmu.2025.1736017

611 views

Original Research

Published on 11 Dec 2025

Peri-tumoural lymphocyte neighbourhoods predict longer survival in pancreatic ductal adenocarcinoma

in Cancer Immunity and Immunotherapy

Riley J. Arseneau
Jorge P. Mejia
Sarah Nersesian
Stacey N. Lee
Carley Bekkers
Thomas Samson
Daniel Gaston
Boris L. Gala-Lopez
Ravi Ramjeesingh
Thomas Arnason

Frontiers in Immunology

doi 10.3389/fimmu.2025.1730817

688 views

Original Research

Published on 11 Dec 2025

MMP-9 affects dural cell composition and granulocyte accumulation during neuroinflammation

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Sheng-Hsiang Shen
Hanna Gerwien
Miriam Burmeister
Yi-Ling Tsang
I-Na Lu
Anna-Lena Börsch
Tushar Deshpande
Lydia Sorokin
Gerd Meyer zu Hörste

Frontiers in Immunology

doi 10.3389/fimmu.2025.1713166

1,608 views

Original Research

Published on 11 Dec 2025

Newborn screening for SCID and severe T- and B-cell lymphopenia in Ukraine: the first analysis of the results, 2022–2025

in Primary Immunodeficiencies

Oksana Boyarchuk
Halyna Makukh
Alla Volokha
Anastasiia Bondarenko
Nataliia Mytsyk
Oksana Barvinska
Ivanna Shymanska
Yuliia Pohuliai
Mykola Veropotvelyan
Anastasia Haviley

Frontiers in Immunology

doi 10.3389/fimmu.2025.1709657

938 views

Original Research

Published on 11 Dec 2025

Risk factors for central hypoventilation in anti-N-methyl-D-aspartate receptor encephalitis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Xuan Zou
Xi-yue Jing
Guan-en Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1718192

392 views

Review

Published on 11 Dec 2025

Unraveling the RKIP–YY1 axis: immune crosstalk in the pathogenesis of metabolic disorders

in Inflammation

Fawaz Alzaid
Hossein Arefanian
Fatemah Bahman
Shaima Albeloushi
Ghadeer Alhamar
Anwar Mohammad
Amal Hasan
Ashraf Al Madhoun
Rasheed Ahmad
Fahd Al-Mulla

Frontiers in Immunology

doi 10.3389/fimmu.2025.1675699

689 views

Systematic Review

Published on 11 Dec 2025

Incidence, risk factors and outcomes of BCGosis following BCG vaccination in infants: a systematic review and meta-analyses

in Vaccines and Molecular Therapeutics

Fathima Raahima Riyas Mohamed
Mudasar Nisar
Ismail Saeed
Mohammed Rushdhi Irfan
Ahlaam Khalid
Muneeb Faiz
Ahmed F. Younis
Shahan Javed
Arya Sen
Asma Azam

Frontiers in Immunology

doi 10.3389/fimmu.2025.1615039

964 views

Original Research

Published on 11 Dec 2025

Mitochondrial calcium shapes B cell signaling and mitochondrial function

in B Cell Biology

Hakan Taskiran
Elena Czeslik
Leonhard Stark
Kathrin Kläsener
Theresa Elisa Schnalzger
Jürgen Ruland
Michael Reth
Julia Jellusova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1710128

577 views

Mini Review

Published on 11 Dec 2025

Tumor associated macrophages in gastric cancer dual roles in immune evasion and clinical implications for targeted therapy

in Molecular Innate Immunity

Chang Wang
Xu Fan
Xiaomen Sun
Yi Xu
Yanna Sun
Jidong Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1706744

739 views

Review

Published on 11 Dec 2025

T cell heterogeneity in asthma pathogenesis: from immunological mechanisms to biological targeted therapies

in T Cell Biology

Qifeng Gan
Yuzhen Zhu
Yuxin Guo
Guo Fu
Xiao-Bin Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1658774

495 views

Original Research

Published on 11 Dec 2025

Therapeutic drug monitoring plays an important role in patients with noninfectious uveitis receiving adalimumab

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Weidong Cheng
Jiayu Xiao
Shengjie Li
Huaru Wang
Shasha Wang
Yujing Qian
Chan Zhao
Fei Gao
Xuzhen Qin
Meifen Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1733644

467 views

Original Research

Published on 11 Dec 2025

Development of a humanized mouse model of graft-versus-host disease to assess human regulatory T cell function

in T Cell Biology

Charline Beguin
Oswin Kwan
Grégory Ehx
Stéphanie Humblet-Baron
Murat Cem Köse
Sophie Dubois
Lorenzo Canti
Justine Courtois
Coline Daulne
Jo Caers

Frontiers in Immunology

doi 10.3389/fimmu.2025.1717133

1,042 views

Case Report

Published on 11 Dec 2025

Case report of acute hepatorenal failure induced by third-line treatment with tislelizumab in a patient with cholangiocarcinoma: was influenza virus the culprit?

in Cancer Immunity and Immunotherapy

Xuebing Zhang
Xia Zhang
Hang Yin
Weiguo Zhang
Bin Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1631953

572 views

48,714 articles

articles

IL-33 and IL-3 synergistically induce CD25 expression on human basophils without functional IL-2 signaling: a potential marker of severe COVID-19

The contribution of amphibian macrophage subsets to scarless regeneration of skin wounds

Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation

Brain TRPV1 channel-mediated calcium influx: the immunomodulatory pathway of acupuncture in neuroinflammation

Glymphatic dysfunction in neuromyelitis optica spectrum disorder

Correction: GATA2 deficiency in an adult with alveolar proteinosis, infections, lymphadenopathy with granulomatosis, and immune deficiency: case report

Prognostic significance of reduced handgrip strength in patients with unresectable hepatocellular carcinoma receiving HAIC combined with targeted immunotherapy

The role of nucleic acid sensors in antifungal immunity

Identification of serum MicroRNAs associated with hepatic immunoinflammatory injury in chronic hepatitis B: implications for non-invasive diagnosis

Vinegar intake in patients undergoing immune checkpoint inhibitor therapy: food frequency questionnaire study

Beneficial effects of food-medicine homologous herbs for patients with diabetic kidney disease

Intrathecal rituximab for the treatment of Epstein–Barr virus-associated encephalitis

Peri-tumoural lymphocyte neighbourhoods predict longer survival in pancreatic ductal adenocarcinoma

MMP-9 affects dural cell composition and granulocyte accumulation during neuroinflammation

Newborn screening for SCID and severe T- and B-cell lymphopenia in Ukraine: the first analysis of the results, 2022–2025

Risk factors for central hypoventilation in anti-N-methyl-D-aspartate receptor encephalitis

Unraveling the RKIP–YY1 axis: immune crosstalk in the pathogenesis of metabolic disorders

Incidence, risk factors and outcomes of BCGosis following BCG vaccination in infants: a systematic review and meta-analyses

Mitochondrial calcium shapes B cell signaling and mitochondrial function

Tumor associated macrophages in gastric cancer dual roles in immune evasion and clinical implications for targeted therapy

T cell heterogeneity in asthma pathogenesis: from immunological mechanisms to biological targeted therapies

Therapeutic drug monitoring plays an important role in patients with noninfectious uveitis receiving adalimumab

Development of a humanized mouse model of graft-versus-host disease to assess human regulatory T cell function

Case report of acute hepatorenal failure induced by third-line treatment with tislelizumab in a patient with cholangiocarcinoma: was influenza virus the culprit?