Frontiers in Immunology

Case Report

Published on 19 Dec 2025

Severe systemic cutaneous adverse reactions following camrelizumab therapy: a case report and literature review

in Cancer Immunity and Immunotherapy

Yuan-dong Sun
Wen-jia Guo
Jian-jun Han

Frontiers in Immunology

doi 10.3389/fimmu.2025.1714201

287 views

Mini Review

Published on 19 Dec 2025

The dual role of thrombospondin-1 in inflammatory regulation during acute respiratory distress syndrome: a mini-review

in Inflammation

YaWen Zheng
Cong Liu
YaJun Li
WenFei Wang
QingLi Dou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1699900

225 views

Original Research

Published on 19 Dec 2025

Longitudinal immune profiling uncovers regulatory T cell signatures associated with the progression of COVID-19

in T Cell Biology

Camila Kossack
Felipe Bravo
Francisco Fuentes-Villalobos
Claudio Quevedo
Matías A. Medina
Raúl Riquelme
María Luisa Rioseco
Mario Calvo
Karina Pino-Lagos
Felipe Aguilera

Frontiers in Immunology

doi 10.3389/fimmu.2025.1697788

349 views

Correction

Published on 19 Dec 2025

Correction: FKBP5-CCL5 interaction promotes neuroinflammation and neuronal apoptosis in ischemic stroke by regulating the MAPK pathway and enhancing NET formation

in Inflammation

Zhongchen Li
Tengkun Yin
Hongyang Guo
Zhenxing Liu
Peijian Wang
Chao Liu
Qingbo Wang
Meng Zhang
Yilei Xiao
Jiyue Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1744810

323 views

Original Research

Published on 19 Dec 2025

PSMD14 drives lung adenocarcinoma progression through HMMR stabilization and dual activation of TGF-β/Smad and PI3K/AKT/mTOR signaling

in Cancer Immunity and Immunotherapy

Rui Chen
Shijing Wang
Junping Xie

Frontiers in Immunology

doi 10.3389/fimmu.2025.1720799

280 views

Correction

Published on 19 Dec 2025

Correction: Targeting ferroptosis: novel therapeutic approaches and intervention strategies for kidney diseases

in Inflammation

Yanfang Luo
Muyang Long
Xueqin Wu
Liuting Zeng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1765613

433 views

Original Research

Published on 19 Dec 2025

Lipocalin-2 modulates recipients alloimmune responses to the murine kidney transplants

in Alloimmunity and Transplantation

Anna Maria Pfefferkorn
Raphaela Fritsche-Guenther
Angelika Kusch
Hubert Schwelberger
Shiqian Liu
Robert Klopfleisch
Yuhuan Li
Rusan Catar
Shaokun Liu
Felix Aigner

Frontiers in Immunology

doi 10.3389/fimmu.2025.1716393

463 views

Original Research

Published on 19 Dec 2025

Systemic immune classification related to immune exhaustion evaluates the clinical response of patients with HBV-HCC after transarterial chemoembolization

in Systems Immunology

Lihua Yu
Xiaoli Liu
Ying Hu
Huiwen Yan
Yuqing Xie
Zimeng Shang
Yuling Liang
Wanxin Shi
Juan Du
Yuyong Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629052

172 views

Review

Published on 19 Dec 2025

Toll-like receptors and their role in the pathogenesis of myasthenia gravis: a comprehensive review

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Xiaoxiao Zheng
Ling Li
Hongyue Ma
Mingxia Zhu
Xiuli Li
Xinhong Feng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1624957

311 views

Original Research

Accepted on 18 Dec 2025

Antigenic assessment for the β2-glycoprotein I/Platelet factor 4 complex in thrombotic patients with antiphospholipid syndrome

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Francesca Villani
Antonella Capozzi
Federica Maria Ucci
Simona Truglia
Manuela De Michele
Silvia Mancuso
Luca Rapino
Giuseppe Tripodi
Valeria Manganelli
Gloria Riitano

Frontiers in Immunology

176 views

Original Research

Accepted on 18 Dec 2025

Intra-tumoral NK cells and their Association with Patient Outcomes: A novel Prognostic model Incorporating NK Cells and Clinicopathologic features in Gastric Cancer

in Cancer Immunity and Immunotherapy

Masanori Oshi
Yuko Tamura
Rongrong Wu
Colin J. Rog
Li Yan
Kizuki Yuza
Takashi Kosaka
Hirotoshi Akiyama
Takashi Ishikawa
Kazuaki Takabe

Frontiers in Immunology

Original Research

Accepted on 18 Dec 2025

Integrated Multi-Omics and Single-Cell Analysis Identify SERPINE1 as a Key Mediator of the Inflammatory Tumor Microenvironment in PDAC

in Cancer Immunity and Immunotherapy

Di Wang
Qing Chen
Can-ming Li
Yan Xie
Chunhui Yuan
Ren Lang
Wen-Tao Jiang

Frontiers in Immunology

Systematic Review

Accepted on 18 Dec 2025

Global Assessment of Hepatic Safety in Novel Immunotherapies: A systematic review and meta-analysis

in Cancer Immunity and Immunotherapy

Minyan Ye
Yinuo Dong
Xiaoyun Li
Yang Zhi
Yuping Lu
Jieting Tang
Wei Zhong
Xiaohong Lei
Yimin Mao
Sha Huang

Frontiers in Immunology

Editorial

Accepted on 18 Dec 2025

Editorial: Unveiling the Next Generation of Cancer Immunity & Immunotherapy

in Cancer Immunity and Immunotherapy

Mohanraj Sadasivam
Nethaji Muniraj
Thangavel Chellappagounder

Frontiers in Immunology

150 views

Original Research

Accepted on 18 Dec 2025

Sex-specific differences in abscopal responses to combined radiotherapy and immune checkpoint inhibition – insights from a multicenter study

in Cancer Immunity and Immunotherapy

Maike Trommer
Alexander Rühle
Felix Ehret
Allison Lamrani
Charlotte Schmitter
Justus Kaufmann
Matthias Mäurer
Georg Wurschi
Ping Jiang
Andrea Baehr

Frontiers in Immunology

Review

Accepted on 18 Dec 2025

ROLE OF EXOSOMES IN GASTROINTESTINAL PHYSIOLOGY AND PATHOPHYSIOLOGY

in Mucosal Immunity

Vivian Naa Amua Wellington
Soudamani Singh

Frontiers in Immunology

Original Research

Accepted on 18 Dec 2025

NETs Drive Myocardial Fibrosis in Hypertension via an NF-κB/Ferroptosis Axis

in Inflammation

QingXian Tu
Xiaowei Gong
Xiaoxi Yuan
Yiyue Tang
Runze Huang
Qianfeng Jiang
Wei Li

Frontiers in Immunology

131 views

Review

Accepted on 18 Dec 2025

The TCR and LCK: Foundations for T-Cell Activation and Therapeutic Innovation

in T Cell Biology

Susana Minguet
Nadine M Wössner
Valeria Uleri
Ondrej Stepanek

Frontiers in Immunology

166 views

Original Research

Accepted on 18 Dec 2025

Erythrocyte Membrane-Encapsulated SZF Nanocomposites for Hyperuricemia Therapy

in Molecular Innate Immunity

Weiwei Liu
Xin Guan
Luobing Wang
Chengjie Zhang
Boyi Shen
Yuke Zeng
Dongdong Li
Guangjin Pu
Jing Hu
Jiandong Gao

Frontiers in Immunology

117 views

Original Research

Accepted on 18 Dec 2025

A Ligand-Centered Framework for γδ T Cell Activation in Colorectal Cancer Revealed by Single-Cell and Transformer-Based Perturbation

in Cancer Immunity and Immunotherapy

Ran Ran
Douglas K. Brubaker

Frontiers in Immunology

Original Research

Accepted on 18 Dec 2025

Single-cell transcriptional profiling revealed the protective effects of Buddleoside in sepsis-associated acute liver injury

in Inflammation

Qingmiao Shi
Na Lou
Leiya Fu
Ying Wang
Chen Xue
Shen Shen
Li Li

Frontiers in Immunology

Correction

Accepted on 18 Dec 2025

Correction: TACE-HAIC versus HAIC combined with TKIs and ICIs for hepatocellular carcinoma with a high tumor burden—a propensity-score matching comparative study

in Cancer Immunity and Immunotherapy

Chun-xue Wu
yunlong Dong
Xinge Li
Wenbo Shao
Guangshun Wang
Huiyong Wu
Xu Chang

Frontiers in Immunology

149 views

Original Research

Accepted on 18 Dec 2025

A rapid method to reduce drug interferences for antibody measurements in pegunigalsidase alfa-treated patients with Fabry disease

in Vaccines and Molecular Therapeutics

Malte Lenders
Elisa Rudolph
Michael Rudnicki
Markus Cybulla
Eva Brand

Frontiers in Immunology

133 views

Correction

Accepted on 18 Dec 2025

Correction: Manganese mediates antiviral effects by driving an ATM - TBK1 phosphorylation signaling pathway

in Molecular Innate Immunity

Hongyan Sui
Rosana Wiscovitch-Russo
Silvia Cachaco
Jun Yang
Whitney Bruchey
Sylvain Laverdure
Qian Chen
Tomozumi Imamichi

Frontiers in Immunology

143 views

48,462 articles

articles

Severe systemic cutaneous adverse reactions following camrelizumab therapy: a case report and literature review

The dual role of thrombospondin-1 in inflammatory regulation during acute respiratory distress syndrome: a mini-review

Longitudinal immune profiling uncovers regulatory T cell signatures associated with the progression of COVID-19

Correction: FKBP5-CCL5 interaction promotes neuroinflammation and neuronal apoptosis in ischemic stroke by regulating the MAPK pathway and enhancing NET formation

PSMD14 drives lung adenocarcinoma progression through HMMR stabilization and dual activation of TGF-β/Smad and PI3K/AKT/mTOR signaling

Correction: Targeting ferroptosis: novel therapeutic approaches and intervention strategies for kidney diseases

Lipocalin-2 modulates recipients alloimmune responses to the murine kidney transplants

Systemic immune classification related to immune exhaustion evaluates the clinical response of patients with HBV-HCC after transarterial chemoembolization

Toll-like receptors and their role in the pathogenesis of myasthenia gravis: a comprehensive review

Antigenic assessment for the β2-glycoprotein I/Platelet factor 4 complex in thrombotic patients with antiphospholipid syndrome

Intra-tumoral NK cells and their Association with Patient Outcomes: A novel Prognostic model Incorporating NK Cells and Clinicopathologic features in Gastric Cancer

Integrated Multi-Omics and Single-Cell Analysis Identify SERPINE1 as a Key Mediator of the Inflammatory Tumor Microenvironment in PDAC

Global Assessment of Hepatic Safety in Novel Immunotherapies: A systematic review and meta-analysis

Editorial: Unveiling the Next Generation of Cancer Immunity & Immunotherapy

Sex-specific differences in abscopal responses to combined radiotherapy and immune checkpoint inhibition – insights from a multicenter study

ROLE OF EXOSOMES IN GASTROINTESTINAL PHYSIOLOGY AND PATHOPHYSIOLOGY

NETs Drive Myocardial Fibrosis in Hypertension via an NF-κB/Ferroptosis Axis

The TCR and LCK: Foundations for T-Cell Activation and Therapeutic Innovation

Erythrocyte Membrane-Encapsulated SZF Nanocomposites for Hyperuricemia Therapy

A Ligand-Centered Framework for γδ T Cell Activation in Colorectal Cancer Revealed by Single-Cell and Transformer-Based Perturbation

Single-cell transcriptional profiling revealed the protective effects of Buddleoside in sepsis-associated acute liver injury

Correction: TACE-HAIC versus HAIC combined with TKIs and ICIs for hepatocellular carcinoma with a high tumor burden—a propensity-score matching comparative study

A rapid method to reduce drug interferences for antibody measurements in pegunigalsidase alfa-treated patients with Fabry disease

Correction: Manganese mediates antiviral effects by driving an ATM - TBK1 phosphorylation signaling pathway