Frontiers in Immunology

Case Report

Accepted on 10 Dec 2025

Epidermolysis bullosa acquisita following dipeptidyl peptidase-4 inhibitor therapy and complicated by immune thrombocytopenic purpura

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Hirofumi Kawamoto
Natsuko Sasaki
Yukimi Ueda
Norito Ishii
Yu Sawada

Frontiers in Immunology

169 views

Original Research

Accepted on 10 Dec 2025

Risk Factors for Cancer and the Importance of Screening in Adult Recipients of Living-Donor Kidney Transplant

in Alloimmunity and Transplantation

Takahisa Hiramitsu
Yuki Shimamoto
Tomoki Himeno
Yuki Hasegawa
Kenta Futamura
Manabu Okada
Yutaka Matsuoka
Norihiko Goto
Toshihiro Ichimori
Shunji Narumi

Frontiers in Immunology

188 views

Original Research

Accepted on 10 Dec 2025

Antigen recognition induces allosteric conformational variability in adalimumab and avelumabAntigen binding triggers long-range conformational changes in monoclonal antibodies

in Vaccines and Molecular Therapeutics

Davide Bianchi
Simona Saporiti
Wolf Palinsky
Omar Ben Mariem
Mara Rossi
Ivano Eberini
Fabio Centola

Frontiers in Immunology

237 views

Review

Accepted on 10 Dec 2025

Double, Double Toil and Trouble: Transforming Growth Factor Beta (TGF-β) in HIV Infection

in Viral Immunology

Jakob Harrison-Gleason
Kayla Lacin Yerlioglu
Ariel Wolfgang Halle
Judd Hultquist
Elena Martinelli

Frontiers in Immunology

185 views

Original Research

Accepted on 10 Dec 2025

Susceptibility of broad reactivity nanobodies to resistance mutations in the S2 domain of SARS-CoV-2 predicted by yeast display deep mutational scanning

in Vaccines and Molecular Therapeutics

Simon Evan Hufton
Christina R Ball
Walter Ramage
Ryan Mate

Frontiers in Immunology

176 views

Original Research

Accepted on 10 Dec 2025

LILRB1 and LILRB2 genomics and transcriptomics in macaque and baboon species: polymorphism, diversification, and extensive alternative splicing

in Comparative Immunology

Natasja G. De Groot
Nanine de Groot
Corrine Heijmans
Annemiek J. M. de Vos-Rouweler
Marit K. H. van der Wiel
Jesse Bruijnesteijn

Frontiers in Immunology

166 views

Original Research

Accepted on 10 Dec 2025

Serum Magnesium Predictive Value in Hepatocellular Carcinoma Patients on First-Line Immunotherapy: A Retrospective Study

in Cancer Immunity and Immunotherapy

Xi Cheng
Wei Wang
Ya-nan Xue
Hong-lin Tang
Da Li

Frontiers in Immunology

262 views

Review

Accepted on 10 Dec 2025

Metabolic Reprogramming in the Post-Metastatic Tumor Microenvironment: Multi-Omics Insights into Determinants of Immunotherapy Response

in Cancer Immunity and Immunotherapy

Mengxi Li
WANG TINGTING
Zhenwang Zhang
Yuxi Dongye

Frontiers in Immunology

186 views

Original Research

Accepted on 10 Dec 2025

Prostate-Specific Membrane Antigen Targeted Organic Semiconducting Polymer Nanoparticles for Enhanced Photothermal Therapy of Prostate Cancer

in Cancer Immunity and Immunotherapy

Zhongji Jiang
Xun Zhang
Gaohaer Kadeerhan
Jin Zhang
Jiali Jin
Weijing Hu
Wenmin Guo
Hong Guo
Dongwen Wang

Frontiers in Immunology

238 views

Original Research

Accepted on 10 Dec 2025

Characterization of T cell responses against Fusobacterium necrophorum naturally-induced foot rot in dairy cows

in Comparative Immunology

Yang Yi
Lulu Zhang
Chen Yu
Sheng Zhang
Chunmei Ye
Zhangping Yang
Zhipeng Zhang

Frontiers in Immunology

174 views

Original Research

Accepted on 10 Dec 2025

Multiplex Autoantibody Screening in Pediatric Type 1 Diabetes: POC Blot vs. ELISA for Gluten-Related Disorders

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Adugna Gudeta Negussie
Patricia Wusterhausen
Dassalegn Muleta
Demise Mulugeta
Mesfin Bekele
Torsten Matthias

Frontiers in Immunology

131 views

Perspective

Accepted on 10 Dec 2025

The Oral-Gut Axis in Chronic Atrophic Gastritis: Current Perspectives and Integrated Strategies

in Mucosal Immunity

Tian Yue Zha
Yonggang Ding
Xingli Xu
Yifan Zhang
Jnwei Guo
Huinan Ge
Luzhou Xu

Frontiers in Immunology

209 views

Mini Review

Accepted on 10 Dec 2025

Natural Killer Cell Exhaustion in Ovarian Cancer: From Molecular Suppression to Therapeutic Revival

in Cancer Immunity and Immunotherapy

Ning Jun
Lan Yao

Frontiers in Immunology

114 views

Review

Published on 10 Dec 2025

Progress in the preparation of an active immunization model of anti-N-methyl-D-aspartate receptor encephalitis in animals

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Kuikui Zeng
Yuting Liu
Sai Yang
Lingjuan Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1585353

617 views

Perspective

Published on 10 Dec 2025

Oncolytic virus therapy for osteosarcoma: mechanisms, opportunities, and challenges

in Cancer Immunity and Immunotherapy

Jia-Wen Wang
Xiaolei Ge
Jia-Hui Liu
Xiaoyu Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1724768

755 views

Review

Published on 10 Dec 2025

Mechanistic roles of neutrophil heterogeneity in tumour pathogenesis

in Cancer Immunity and Immunotherapy

Hua Lin
Yutian Liao
Zhonghui Chen
Ye Chen
Yating Chen
Yulin Wang
Zhanfei Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1721090

724 views

Original Research

Published on 10 Dec 2025

COL8A1 as a pro-inflammatory mediator bridges immune evasion and therapy resistance in glioma

in Cancer Immunity and Immunotherapy

Jiachong Wang
Jiale Li
Jun Peng
Chunyuan Zhang
Zigui Chen
Changfeng Miao
Chunhai Tang
Qisheng Luo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1727298

602 views

Review

Published on 10 Dec 2025

Research progress on the role and mechanism of circadian clock gene PER1 in the occurrence and development of multiple diseases

in Inflammation

Yuxiang Zhao
Yujin Li
Tingting Lu
Xinyue Huang
Kerui Chen
Lina Tan
Lihua Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1715457

851 views

Original Research

Published on 10 Dec 2025

RPL41 inhibits the proliferation and migration of retinoblastoma through the ARL5B-associated lysosomal trafficking

in Cancer Immunity and Immunotherapy

Ye Li
Tian Zhan
Tianfu Chen
Qianwen Zhong
Sheng Xiao
Aiyuan Wang
Yisheng Jiao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1704080

565 views

Review

Published on 10 Dec 2025

Research progress on the induction of immunogenic cell death in tumor immunotherapy using a sonodynamic therapy nanoparticle delivery system

in Cancer Immunity and Immunotherapy

Yang Du
Jiangnan Yang
An Xu
Shuai Chen
Deyuan Fu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1681773

810 views

Original Research

Published on 10 Dec 2025

Synergistic effects of vedolizumab and JAK 1,2,3 inhibitors in Crohn’s disease: insights from a systems biology and artificial intelligence-based approach

in Systems Immunology

Ignacio Marín-Jiménez
Mónica Sierra-Ausín
Teresa Letosa-Abián
Jesús Aparicio
Carmen Montoto-Otero
Silvia Sánchez-Ramón

Frontiers in Immunology

doi 10.3389/fimmu.2025.1699203

1,058 views

Original Research

Published on 10 Dec 2025

RARS1 inhibits ENO1 ubiquitination and degradation to protect against ferroptosis in hepatocellular carcinoma

in Cancer Immunity and Immunotherapy

Shouge Zang
Jvlong Ma
Lichang Chen
Di Cui
Jiangtao Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1686597

932 views

Original Research

Published on 10 Dec 2025

Health-related quality of life and psychosocial outcomes in long-term survivors treated with immune checkpoint inhibitors: a nationwide multicenter study

in Cancer Immunity and Immunotherapy

Taha Koray Sahin
Fatih Atalah
Bahadir Koylu
Ahmet Oruc
Aydin Acarbay
Akgun Karakok
Sevgi Dogan
Cevat Ilteris Kikili
Görkem Turhan
Gamze Emin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1693295

820 views

Review

Published on 10 Dec 2025

Traditional Chinese medicine as potential adjuvants for tumor vaccines: a review of types, mechanisms, and forms

in Cancer Immunity and Immunotherapy

Yongjia Cui
Lutian Gong
Lei Chang
Wenping Lu
Siqing Zhao
Zhili Zhuo
Xiangyang Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661694

995 views