Frontiers in Immunology

Original Research

Published on 10 Dec 2025

Circulating PD-1+ effector memory T cells predict anti-PD-1 efficacy in advanced gastric cancer

in Cancer Immunity and Immunotherapy

Kongcheng Wang
Jie Shao
Kai Xin
Lianru Zhang
Baorui Liu
Wenxiu Chen
Qin Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1720724

722 views

Original Research

Published on 10 Dec 2025

Impact of celiac disease on patients with familial Mediterranean fever: a nationwide study based on the Türkiye database

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Rıfat Bozkuş
Serdar Can Güven
Salih Başer
Nuray Yılmaz Çakmak
Hasan Satış
Emin Gemcioğlu
Naim Ata
Şuayip Birinci

Frontiers in Immunology

doi 10.3389/fimmu.2025.1675131

629 views

Systematic Review

Published on 10 Dec 2025

A bibliometric analysis of vaccine research on Chikungunya virus: contributors, trends, and emerging frontiers

in Vaccines and Molecular Therapeutics

Da Shao
Zengwei Kou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1692556

946 views

Review

Published on 10 Dec 2025

Immune-mediated blood-brain barrier disruption after ischemic stroke: mechanisms and therapeutic targets

in Inflammation

Hanjing Wang
Zhang Yiqiang
Jie Cai
Jiawei Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1716041

930 views

Case Report

Published on 10 Dec 2025

IgG4-related disease presenting with hypercalcemia: case report and mechanistic insights

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yaxin Li
Xing Niu
Ling Li
Zhangxue Hu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1720791

789 views

Review

Published on 10 Dec 2025

Multi-omics approach to dissect the significance of lipid metabolism in helper T cell subset

in Inflammation

Toshio Kanno
Keiko Nakano
Yukie Iwao
Yusuke Endo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1708616

691 views

Original Research

Published on 10 Dec 2025

Efficacy and safety of immunotherapy rechallenge in second-line treatment after failure of first-line immune checkpoint inhibitors combined with chemotherapy in advanced gastric cancer: a retrospective study

in Cancer Immunity and Immunotherapy

Fei Li
Wenjing Gong
Miaomiao Yang
Aina Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1697712

771 views

Original Research

Published on 10 Dec 2025

Insomnia and anxiety: exploring their hidden effect on natural killer cells among young female adults

in NK and Innate Lymphoid Cell Biology

Renad M. Alhamawi
Fatmah A. Halawani
Sima F. Hakeem
Hadeel A. Alslimi
Ebraheim M. Alhamawi
Ahmed M. Aljohani
Ibrahim N. Mohammed
Heba M. Zahid
Yahya A. Almutawif

Frontiers in Immunology

doi 10.3389/fimmu.2025.1698155

3,501 views

Original Research

Published on 10 Dec 2025

PRR enhances anti-tumor immunity and suppresses colitis by promoting the development and survival of naive T and iNKT cells

in T Cell Biology

Akihiro Shimba
Satoru Munakata
Shinya Abe
Guangwei Cui
Ryoma Kato
Masaki Miyazaki
Atsuhiro Ichihara
Koichi Ikuta

Frontiers in Immunology

doi 10.3389/fimmu.2025.1566935

708 views

Review

Accepted on 09 Dec 2025

THE ROLE OF IMMUNOGLOBULIN E IN NON-ATOPIC DISORDERS

in Cytokines and Soluble Mediators in Immunity

Kujtim Thaçi
Aron Gyorgypal
Robert Anthony
Michelle Conroy

Frontiers in Immunology

340 views

Original Research

Accepted on 09 Dec 2025

Neuronal autoantibodies associated with poorer neuropsychological and motor outcomes 6 months after stroke: Results from the PHYS-STROKE trial

in Multiple Sclerosis and Neuroimmunology

Charlotte Pietrock
Konrad Neumann
Kristin Rentzsch
Harald Prüss
Andreas Meisel
Matthias Endres
Alexander Heinrich Nave

Frontiers in Immunology

264 views

Systematic Review

Accepted on 09 Dec 2025

Sacituzumab Govitecan as a Therapeutic Breakthrough in the Treatment of Triple-Negative Breast Cancer: A Systematic Review of Clinical Trials

in Cancer Immunity and Immunotherapy

Julia Piekarz
Natalia Picheta
Jakub Pobideł
Katarzyna Szklener
Sławomir Mańdziuk

Frontiers in Immunology

273 views

Original Research

Accepted on 09 Dec 2025

Intratumor Heterogeneity Score Reveals Immune Landscape and Survival Stratification in Colorectal Cancer

in Cancer Immunity and Immunotherapy

Zijing Wang
Liyuan Ma
Jinzhong Cao
Xi Chen
Xin Chang
Ruxue Ma
Hengyi Lv
Zixin Zhang
Hai Li
Tao Jiang

Frontiers in Immunology

218 views

Original Research

Accepted on 09 Dec 2025

ATOMIC: a graph attention network for atopic dermatitis prediction using human gut microbiome

in Systems Immunology

Hyunsu Bong
Joonhong Min
Songhyeon Kim
Wootaek Lim
Dongyoung Lim
Hyunjeong Eom
Young Her
Minji Jeon

Frontiers in Immunology

266 views

Original Research

Accepted on 09 Dec 2025

Sustained STING-IRF7 signaling aggravates LPS-induced endometrial inflammation via excessive neutrophil extracellular traps generation

in Molecular Innate Immunity

Min Chu
Ding Ma
Zhan Song
Li Liang
Fengjuan Xing
Hongchu Bao

Frontiers in Immunology

146 views

Review

Accepted on 09 Dec 2025

The Multifaceted Role of Post-Translational Modifications in Macrophage Polarization: From Mechanisms to Therapeutic Targets

in Molecular Innate Immunity

Rui Guo
Feng Qi

Frontiers in Immunology

147 views

Review

Accepted on 09 Dec 2025

Molecular Mechanisms and Therapeutic Progress in Atherosclerosis: Bridging Immune Inflammation and Precision Medicine

in Inflammation

Yimin Han
Hongyi Xu
Xinlei Yao
Zhanzhan Li
Chuli Zhu
Xia Li
Bingqian Chen
Hualin Sun

Frontiers in Immunology

184 views

Original Research

Accepted on 09 Dec 2025

Farrerol inhibits ferroptosis and protects against LPS-induced acute lung injury by targeting the RUNX1/SLC7A11 axis

in Inflammation

Ying Xu
Yueyan Yang
Shihua Deng
Teng Liu
Min Yang
Xintao Zhang
Xiaobian Wang
Sunhan Zhang
Ting Zhang
Dongming Wu

Frontiers in Immunology

178 views

Original Research

Accepted on 09 Dec 2025

Deciphering Immune Cell Interaction Aberrations in Necrotizing Enterocolitis: The Regulatory Role of DHRS7

in Inflammation

Kexin Gao
Yuehua Chen
Lu Jingjing
Wenliang Ge
Qiyou Yin

Frontiers in Immunology

146 views

Original Research

Accepted on 09 Dec 2025

Identification of Immune-Related Prognostic Biomarkers in Lung Squamous Cell Carcinoma Microenvironment

in Cancer Immunity and Immunotherapy

Zhihao Wang
Zhengsheng Wu

Frontiers in Immunology

215 views

Original Research

Accepted on 09 Dec 2025

NDUFS4, a Mitochondrial Complex I Subunit, is Essential for T-Cell Metabolic Fitness and Immune Function

in T Cell Biology

Oded Shamriz
Zahala Bar-On
Omri Yosef
Leonor Cohen-Daniel
Ayelet Sheer
Or Reuven
Wajeeh Salaymeh
Amijai Saragovi
Raz Somech
Atar Lev

Frontiers in Immunology

302 views

Original Research

Accepted on 09 Dec 2025

Fc-enhanced anti-CCR6 antibody elicits Robust Therapeutic Effects Across Multiple Autoimmune Diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Md Jahangir Alam
Yu-Anne Yap
Caroline Ang
Liang Xie
Hillary L. Shane
Charles R. Mackay
Remy Robert

Frontiers in Immunology

309 views

Systematic Review

Accepted on 09 Dec 2025

Bio-Boosting Transplants: A Systematic Review on Biopolymers in Vascular Composite Allotransplantation

in Alloimmunity and Transplantation

Leonard Knoedler
Tobias Niederegger
Thomas Schaschinger
Jakob Fenske
Varun P. A. Murugan
Samuel Knoedler
Max Heiland
Adriana C. Panayi
Gabriel Hundeshagen
Alexandre G. Lellouch

Frontiers in Immunology

181 views

Original Research

Accepted on 09 Dec 2025

Strongyloides stercoralis Coinfection Impairs Immune Control of Mycobacterium tuberculosis in TB infected individuals

in Parasite Immunology

Anuradha Rajamanickam
Bindu Dasan
Arul Nancy
Saravanan Munisankar
Siva Kumar Shanmugam
Subash Babu

Frontiers in Immunology

257 views

48,741 articles

articles

Circulating PD-1+ effector memory T cells predict anti-PD-1 efficacy in advanced gastric cancer

Impact of celiac disease on patients with familial Mediterranean fever: a nationwide study based on the Türkiye database

A bibliometric analysis of vaccine research on Chikungunya virus: contributors, trends, and emerging frontiers

Immune-mediated blood-brain barrier disruption after ischemic stroke: mechanisms and therapeutic targets

IgG4-related disease presenting with hypercalcemia: case report and mechanistic insights

Multi-omics approach to dissect the significance of lipid metabolism in helper T cell subset

Efficacy and safety of immunotherapy rechallenge in second-line treatment after failure of first-line immune checkpoint inhibitors combined with chemotherapy in advanced gastric cancer: a retrospective study

Insomnia and anxiety: exploring their hidden effect on natural killer cells among young female adults

PRR enhances anti-tumor immunity and suppresses colitis by promoting the development and survival of naive T and iNKT cells

THE ROLE OF IMMUNOGLOBULIN E IN NON-ATOPIC DISORDERS

Neuronal autoantibodies associated with poorer neuropsychological and motor outcomes 6 months after stroke: Results from the PHYS-STROKE trial

Sacituzumab Govitecan as a Therapeutic Breakthrough in the Treatment of Triple-Negative Breast Cancer: A Systematic Review of Clinical Trials

Intratumor Heterogeneity Score Reveals Immune Landscape and Survival Stratification in Colorectal Cancer

ATOMIC: a graph attention network for atopic dermatitis prediction using human gut microbiome

Sustained STING-IRF7 signaling aggravates LPS-induced endometrial inflammation via excessive neutrophil extracellular traps generation

The Multifaceted Role of Post-Translational Modifications in Macrophage Polarization: From Mechanisms to Therapeutic Targets

Molecular Mechanisms and Therapeutic Progress in Atherosclerosis: Bridging Immune Inflammation and Precision Medicine

Farrerol inhibits ferroptosis and protects against LPS-induced acute lung injury by targeting the RUNX1/SLC7A11 axis

Deciphering Immune Cell Interaction Aberrations in Necrotizing Enterocolitis: The Regulatory Role of DHRS7

Identification of Immune-Related Prognostic Biomarkers in Lung Squamous Cell Carcinoma Microenvironment

NDUFS4, a Mitochondrial Complex I Subunit, is Essential for T-Cell Metabolic Fitness and Immune Function

Fc-enhanced anti-CCR6 antibody elicits Robust Therapeutic Effects Across Multiple Autoimmune Diseases

Bio-Boosting Transplants: A Systematic Review on Biopolymers in Vascular Composite Allotransplantation

Strongyloides stercoralis Coinfection Impairs Immune Control of Mycobacterium tuberculosis in TB infected individuals