Frontiers in Immunology

Original Research

Accepted on 19 Jan 2026

Impact of Immune-Related Adverse Events on Treatment Outcomes in Advanced Esophageal Squamous Cell Carcinoma Treated with Immune Checkpoint Inhibitors

in Cancer Immunity and Immunotherapy

Tianhang Zhang
Xiao Chen
Jianhua Wu
Jiasong Li
Zhukun Qin
Ruijie Cao
Wei Guo
Zhanjun Guo
Haiyan Fan

Frontiers in Immunology

117 views

Original Research

Accepted on 19 Jan 2026

Tuft-cell-derived IL-25 Regulates Intestinal ILC2 in Response to Brucella Infection

in Mucosal Immunity

Kaiyu Shang
Na Chen
Tingting Tian
Shi Huidong
Juan Shi
Xinxin Qi
Yuejie Zhu
Fengbo Zhang

Frontiers in Immunology

143 views

Brief Research Report

Accepted on 19 Jan 2026

High throughput profiling of the B cell repertoire identifies systematic changes in the repertoire of individuals with Crohn's disease

in B Cell Biology

Aya K.H. Mahdy
Zahra Taheri
Marte Lie Høivik
Andre Franke
Hesham ElAbd

Frontiers in Immunology

150 views

Original Research

Accepted on 19 Jan 2026

Possible role of pre-vaccination T-lymphocyte subpopulations in the antibody response to COVID-19 vaccines in children undergoing chemotherapy

in Vaccines and Molecular Therapeutics

Csaba Péterfia
Zsolt István Komlósi
Zoltán Pós
Nikolett Lupsa
Nóra Fekete
Katalin Böröcz
Timea Dergez
Evelin Leibinger
Benedek Noemi
Ágnes Vojcek

Frontiers in Immunology

111 views

Original Research

Accepted on 19 Jan 2026

mRNA-based SARS-CoV-2 vaccines: Intracellular processing and aggregation of the encoded spike protein as a mechanistic contributor to cardiac cellular stress

in Vaccines and Molecular Therapeutics

Rolf Schreckenberg
Nadine Woitasky
Nadja Itani
Laureen Czech
Anita Cornelia Windhorst
Malte Juchem
Christian Bär
Thomas Thum
Péter Ferdinandy
Rainer Schulz

Frontiers in Immunology

19,135 views

Original Research

Accepted on 19 Jan 2026

Recombinant ROP8 Antigen: Diagnostics, Immunogenicity, and Therapeutic Targeting in Toxoplasmosis

in Parasite Immunology

Maciej Chyb
Adrian Bekier
Malwina Kawka
Bartłomiej Tomasz Ferra
Bożena Dziadek
Sylwia Michlewska
Katarzyna Dzitko
Nazar Trotsko
Justyna Gatkowska

Frontiers in Immunology

146 views

Review

Accepted on 19 Jan 2026

The Emerging Role of m⁶A Methylation in Prostate-Related Diseases: Mechanisms and Clinical Implications

in Cancer Immunity and Immunotherapy

Qinghua Xie
Hongyan Zhao
Xuan Yang
Hongqi Zhang
Hong Liu
Jinghua Pan
Yan Li
Danping Fan
Xinrong Fan

Frontiers in Immunology

114 views

Original Research

Accepted on 19 Jan 2026

Impact of rice wine-steamed Cistanche deserticola polysaccharides on intestinal flora and immunological modulation in immunosuppressive mice induced by cyclophosphamide

in Nutritional Immunology

Jing Lian
Yuexin Zhu
Qiushi Hu
Kexu Dong
Zihang Peng
Yurou Feng
Na Ling
Caina Yu
Pengpeng Liu
Ji Shi

Frontiers in Immunology

216 views

Original Research

Accepted on 19 Jan 2026

Telitacicept for Refractory AChR-Positive Generalized Myasthenia Gravis: A Retrospective Real-World Study

in Multiple Sclerosis and Neuroimmunology

Xi Rong
Xupeng Sun
Li Wang
Meijie Qu
Liwei Jiang
Min Liu

Frontiers in Immunology

159 views

Original Research

Accepted on 19 Jan 2026

Transcriptomic and proteomic profiling of pulmonary mucormycosis reveals a failed activation of host immune response

in Microbial Immunology

Jinjin Zhong
Xiaomin Cai
Yuchen Cai
Tingting Zhao
Die Hu
Chao Sun
Yueyan Ni
Yu Gu
Xin Su

Frontiers in Immunology

120 views

Mini Review

Accepted on 19 Jan 2026

Advances in T Cell–Based Immunotherapy for Osteosarcoma

in Cancer Immunity and Immunotherapy

Kun Zhang
Zheng Wang
Jiaqi He
Liuru Lu
Wenshu Wang
Aiwei Yang
Huayi Xie
Linhui Huang
Yuying Huang
Ke Zhang

Frontiers in Immunology

134 views

Original Research

Accepted on 19 Jan 2026

Targeted Expression of the Immunomodulatory Peptide Scy by Engineered Escherichia coli Nissle 1917 for Alleviating Enterotoxigenic E. coli Infection

in Mucosal Immunity

Jie Fu
Lutong Zhou
Yanli Chen
Hong Zhang
Lei Qiao
Mingliang Jin
Caiqiao Zhang
Yizhen Wang
Yuanzhi Cheng

Frontiers in Immunology

141 views

Original Research

Accepted on 19 Jan 2026

ProMMF_Kron: A Multimodal Deep Learning Model for Immunotherapy Response Prediction in Stomach Adenocarcinoma

in Cancer Immunity and Immunotherapy

Chenchen Wang
Weikun Liu
Dongmei Ai
Xiuqin Liu

Frontiers in Immunology

166 views

Original Research

Accepted on 19 Jan 2026

Urinary Extracellular Vesicle Metabolomic Profiling Reveals a Distinct Molecular Signature for the Non-Invasive Diagnosis of Lupus Nephritis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Nan Zhang
Ning Dong
Anran Xie
Wenjing Liu
Adeel Khan
Yanjing Rui
Zhiyang Li
Ping Yang

Frontiers in Immunology

Review

Accepted on 19 Jan 2026

Immunoglobulin G N-glycosylation remodeling in viral infections: Immunomodulatory roles and potential biomarker implications

in Viral Immunology

Ruxu Yan
Chunqing Wang
Xuezhen Zhao
Yingjie Wang
Meng Liu
Xiaohong Shi
Hanxiang Chen
Xiaohong Shi

Frontiers in Immunology

119 views

Review

Accepted on 19 Jan 2026

Colorectal cancer-derived extracellular vesicles: at the crossroads of the tumor microenvironment and gut microbiota

in Cancer Immunity and Immunotherapy

Hao Li
Wei Zhang
Wenhui Yan
Kun Wang
Si Chen
Yamao Li
Anzhi Sheng
Anquan Shang
Bingjie Zeng

Frontiers in Immunology

Review

Accepted on 19 Jan 2026

Ferroptosis and Alzheimer's Disease: A New Insight into Neurodegeneration

in Inflammation

Youfang Quan
Hongwei Liu
Minheng Zhang
Meng Li
Bo He
Ke Wang
Xuewen Huang
Shengyang Zhou
Zhongyu Han
Haixia Fan

Frontiers in Immunology

Systematic Review

Accepted on 19 Jan 2026

Efficacy and safety of six immunoadsorption treatments for severe lupus nephritis: a Bayesian network meta-analysis and systematic review

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yin Zheng
zhen Jia Liu
xin Xu Zhang
wei Ke Jia
ni Jia Xia
ning Yi Xu
tong Si Wu
Hong Ji

Frontiers in Immunology

199 views

Original Research

Accepted on 19 Jan 2026

7-Ketocholesterol promotes T cell migration through Ca2+-NFATc1 pathway-mediated F-actin polymerization and proinflammatory cytokine production in oral lichen planus

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Qin Jiang
Yu -Xi Tang
Gang Zhou

Frontiers in Immunology

Original Research

Accepted on 19 Jan 2026

Identification and Histological Validation of Autophagy-Related Core Genes ADRB2 and PLK2 in Keloids, with Integrated Immune Infiltration Analysis

in Inflammation

Junjie Jin
Yue Jin
Bo Lu
Zhehu Jin

Frontiers in Immunology

103 views

Original Research

Accepted on 19 Jan 2026

PHLDA1 is a Shared Diagnostic and Key Mediator of Inflammatory Fibrosis in Heart and Kidney

in Inflammation

Lei Hua
Liangru Shen
Yongshou Tao
Chentong Wang
Xiaohang Shao

Frontiers in Immunology

136 views

Original Research

Accepted on 19 Jan 2026

Integrating Network Pharmacology, Microbiomics, and Metabolomics to Uncover the Therapeutic Effect of Liubao Tea on Osteoarthritis

in Inflammation

Le Guoping
Wen Riyou
Huang Zhifa
Fang Huaixi
Zheng Jianwei
Luo Hanwen

Frontiers in Immunology

151 views

Editorial

Published on 19 Jan 2026

Editorial: Strategies aimed at improving the effectiveness of immunotherapies in pediatric brain cancer

in Cancer Immunity and Immunotherapy

Samuele Tardito
Dalia Haydar
Yi Cao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1771946

609 views

Review

Published on 19 Jan 2026

Therapeutic vaccines targeting HPV epitopes in human papillomavirus – positive oropharyngeal cancer: a critical review

in Cancer Immunity and Immunotherapy

Giovanna Rossi
Francesco Carlo Tartaglia
Nerina Denaro
Michele Ghidini
Funda Goker
Ornella Garrone
Aldo Bruno Giannì
Massimo Del Fabbro
Gianluca Martino Tartaglia
Paolo Bossi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1727804

1,432 views

49,555 articles

articles

Impact of Immune-Related Adverse Events on Treatment Outcomes in Advanced Esophageal Squamous Cell Carcinoma Treated with Immune Checkpoint Inhibitors

Tuft-cell-derived IL-25 Regulates Intestinal ILC2 in Response to Brucella Infection

High throughput profiling of the B cell repertoire identifies systematic changes in the repertoire of individuals with Crohn's disease

Possible role of pre-vaccination T-lymphocyte subpopulations in the antibody response to COVID-19 vaccines in children undergoing chemotherapy

mRNA-based SARS-CoV-2 vaccines: Intracellular processing and aggregation of the encoded spike protein as a mechanistic contributor to cardiac cellular stress

Recombinant ROP8 Antigen: Diagnostics, Immunogenicity, and Therapeutic Targeting in Toxoplasmosis

The Emerging Role of m⁶A Methylation in Prostate-Related Diseases: Mechanisms and Clinical Implications

Impact of rice wine-steamed Cistanche deserticola polysaccharides on intestinal flora and immunological modulation in immunosuppressive mice induced by cyclophosphamide

Telitacicept for Refractory AChR-Positive Generalized Myasthenia Gravis: A Retrospective Real-World Study

Transcriptomic and proteomic profiling of pulmonary mucormycosis reveals a failed activation of host immune response

Advances in T Cell–Based Immunotherapy for Osteosarcoma

Targeted Expression of the Immunomodulatory Peptide Scy by Engineered Escherichia coli Nissle 1917 for Alleviating Enterotoxigenic E. coli Infection

ProMMF_Kron: A Multimodal Deep Learning Model for Immunotherapy Response Prediction in Stomach Adenocarcinoma

Urinary Extracellular Vesicle Metabolomic Profiling Reveals a Distinct Molecular Signature for the Non-Invasive Diagnosis of Lupus Nephritis

Immunoglobulin G N-glycosylation remodeling in viral infections: Immunomodulatory roles and potential biomarker implications

Colorectal cancer-derived extracellular vesicles: at the crossroads of the tumor microenvironment and gut microbiota

Ferroptosis and Alzheimer's Disease: A New Insight into Neurodegeneration

Efficacy and safety of six immunoadsorption treatments for severe lupus nephritis: a Bayesian network meta-analysis and systematic review

7-Ketocholesterol promotes T cell migration through Ca2+-NFATc1 pathway-mediated F-actin polymerization and proinflammatory cytokine production in oral lichen planus

Identification and Histological Validation of Autophagy-Related Core Genes ADRB2 and PLK2 in Keloids, with Integrated Immune Infiltration Analysis

PHLDA1 is a Shared Diagnostic and Key Mediator of Inflammatory Fibrosis in Heart and Kidney

Integrating Network Pharmacology, Microbiomics, and Metabolomics to Uncover the Therapeutic Effect of Liubao Tea on Osteoarthritis

Editorial: Strategies aimed at improving the effectiveness of immunotherapies in pediatric brain cancer

Therapeutic vaccines targeting HPV epitopes in human papillomavirus – positive oropharyngeal cancer: a critical review