Frontiers in Immunology

Original Research

Published on 19 Jan 2026

Telitacicept versus belimumab in proliferative lupus nephritis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Chang Wang
Man-Zhu Zhang
Xiao-Ying Yun
Ling-Xu Li
Jia-Wei Shan
Biao Liu
Bing Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1715593

518 views

Original Research

Published on 19 Jan 2026

Moving for optimal immunity: the effect of acute high-intensity interval training on phenotype, virus specificity and chemokine receptor expression in human CD8+ T cells

in T Cell Biology

Katharina Leuchte
Thy Viet Luu
Sara Fresnillo Saló
Kasper Madsen
Lise Heide-Ottosen
Signe Koggersbøl Skadborg
Janine Sophie Kemming
Morten Orebo Holmström
Hongjin Chen
Lars Rønn Olsen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1739657

1,316 views

Systematic Review

Published on 19 Jan 2026

Bio-boosting transplants: a systematic review on biopolymers in vascular composite allotransplantation

in Alloimmunity and Transplantation

Leonard Knoedler
Tobias Niederegger
Thomas Schaschinger
Jakob Fenske
Varun P. A. Murugan
Samuel Knoedler
Max Heiland
Adriana C. Panayi
Gabriel Hundeshagen
Alexandre G. Lellouch

Frontiers in Immunology

doi 10.3389/fimmu.2025.1645261

815 views

Editorial

Published on 19 Jan 2026

Editorial: Roles of macrophages and monocytes in resistance to immunotherapy in cancers

in Cancer Immunity and Immunotherapy

Guillaume Mestrallet
Susanna Mandruzzato

Frontiers in Immunology

doi 10.3389/fimmu.2026.1784612

512 views

Correction

Published on 19 Jan 2026

Correction: Interventional effects of mesenchymal stem cells on epithelial-mesenchymal transition in head and neck squamous cell carcinoma and underlying mechanisms: a systematic review and meta-analysis of in vitro studies

in Cancer Immunity and Immunotherapy

Youhu Wang
Yanli Liu
Wanxian Du
Jing Xue
Jianhua Ruan
Juan Yu
Bin Ma
Xun Li

Frontiers in Immunology

doi 10.3389/fimmu.2026.1786161

221 views

Mini Review

Published on 19 Jan 2026

Exo-nanomaterials in cancer immunotherapy: reprogramming the tumor immune microenvironment

in Cancer Immunity and Immunotherapy

WeiJian Fang
EnDuo Qiu
Rui Liu
ShanLin Wang
TianFu Wang
YuMing Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1764525

664 views

Original Research

Published on 19 Jan 2026

Oral tolerogenic vaccine combined with gastrin restores immune tolerance and beta-cell function in NOD mice with Type 1 diabetes

in Mucosal Immunity

Jacob Cobb
Jeffrey Rawson
Nelson Gonzalez
Fouad Kandeel
Mohamed I. Husseiny

Frontiers in Immunology

doi 10.3389/fimmu.2025.1740385

784 views

Original Research

Published on 19 Jan 2026

Synergistic effects of platelet-rich fibrin and CTLA4Ig gene-transfected porcine skin on accelerating wound healing in a rat model of deep second-degree burns: a mechanistic study

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Jiliang Li
Chongwei Xu
Leyi Chen
Jiaqi Lou
Hong Kong
Youfen Fan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1756818

553 views

Correction

Accepted on 16 Jan 2026

Correction: Promiscuous class II-binding SARS-CoV-2-nuc derived vaccine-peptide induced extensive conventional, innate and unconventional T cell responses

in Vaccines and Molecular Therapeutics

Karin Schilbach
Naomi Krickeberg
Hans-Georg --- Rammensee

Frontiers in Immunology

268 views

Review

Accepted on 16 Jan 2026

Mechanisms and Therapeutic of Immunometabolic Reprogramming Driving Macrophage-Endothelial Cell Interactions in Sepsis-Associated ARDS from the Gut-Lung Axis Perspective

in Inflammation

Jia Tang
Mi Yan
Mengchun Li
Wanwei Li
Zhangxue Hu

Frontiers in Immunology

159 views

Hypothesis and Theory

Accepted on 16 Jan 2026

The Microbial Peace-Signal Hypothesis: A Unified Framework for Lifelong Immune Restraint

in Microbial Immunology

Cliff Shunsheng Han

Frontiers in Immunology

117 views

Review

Accepted on 16 Jan 2026

Blood-based Epigenetic Biomarkers in Rheumatoid arthritis: Current Knowledge and Future Perspectives

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Agnieszka Mołoń
Hubert Kubis
Joanna Żurawska
Marek Cieśla

Frontiers in Immunology

172 views

Original Research

Accepted on 16 Jan 2026

Dynamics of leukocyte populations, immune-regulatory cytokines, and biochemical parameters in wild boar and domestic pigs experimentally infected with a virulent African swine fever virus genotype II strain

in Comparative Immunology

Giulia Franzoni
Fabian Z. X. Lean
Emanuela Giaconi
Giuseppe Tedde
Susanna Zinellu
Paola Nicolussi
Mireille Le Dimna
Marie-Frédérique Le Potier
Elliot Steedman
Helen Rachel Crooke

Frontiers in Immunology

263 views

Original Research

Accepted on 16 Jan 2026

FFPE-based Proteomics and Machine Learning Reveal Immune Microenvironment Features and Distant Metastasis Risk in N1c Colorectal Cancer

in Cancer Immunity and Immunotherapy

Chenxiao Zheng
Qiongying Zhang
Peng Li
Haobo Jin
Hangjia Xu
Yating Zheng
Yanyu Chen
Zihan Wang
Baiwang Zhu
Xiaodong Zhang

Frontiers in Immunology

146 views

Systematic Review

Published on 16 Jan 2026

Association between statin use and the risk of colorectal cancer in patients with inflammatory bowel disease: a systematic review and meta-analysis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Meng Ding
Yang Liu
Ying Zhang
Yunfeng Qiu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1693342

775 views

Original Research

Published on 16 Jan 2026

Histone lactylation-derived TET2 enhanced Arg1-mediated MDSC immunosuppression

in Cancer Immunity and Immunotherapy

Wenxin Da
Yao Dai
Bo Shen
Yan Zhang
Pengtao Bao
Wei Zhu
Deqiang Wang
Shengjun Wang
Jie Ma

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677780

644 views

Original Research

Published on 16 Jan 2026

Impact of treatment interruption on the efficacy and safety of vunakizumab in patients with moderate-to-severe plaque psoriasis: a post-hoc analysis of a phase 3 trial

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Qunyan Li
Weifeng Yao
Dongyun Lei
Yan Xu
Litao Zhang
Zuotao Zhao
Junchen He
Tao Guo
Junying Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639049

769 views

Original Research

Published on 16 Jan 2026

Transpresentation of interleukin 15 by stromal cell subsets regulates immune cell homeostasis

in Cytokines and Soluble Mediators in Immunity

Carmen Stecher
Romana Bischl
Elisabeth Potzmann
Anna Schmid-Böse
Stefanie Ferstl
Nina Braun
Ellen R. Richie
Matthias Farlik
Richard A. Flavell
Dietmar Herndler-Brandstetter

Frontiers in Immunology

doi 10.3389/fimmu.2025.1673309

951 views

Original Research

Published on 16 Jan 2026

IL-12-armed oncolytic HSV-2 enhances CAR T cell efficacy against pancreatic cancer in xenografted models

in Cancer Immunity and Immunotherapy

Chongfeng Xu
Jian Wu
Weikang Liu
Xiaoya Zhou
Qian Liang
Guoya Li
Yang Wang
Yanliang Liu
Qiying Cai
Zilong Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1664289

815 views

Review

Published on 16 Jan 2026

Flavin and deazaflavin biosynthesis in mycobacteria: relevance to physiology, implications for drug discovery, MR-1 antigenicity, and vaccine development

in Vaccines and Molecular Therapeutics

Nurudeen Oketade
Melissa D. Chengalroyen
Dylan Kain
David M. Lewinsohn
Karen M. Dobos

Frontiers in Immunology

doi 10.3389/fimmu.2025.1656167

1,096 views

Review

Published on 16 Jan 2026

Internalization-related host factors of common respiratory viruses

in Viral Immunology

Qiuchi Lv
Zhengde Xie
Lili Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1724561

668 views

Perspective

Published on 16 Jan 2026

“Brake” and “accelerator”: revisiting tumor cell direct responses and the paradox of aggression in anti-VEGF therapy

in Cancer Immunity and Immunotherapy

Pei Wei
Jiaqi Li
Xueyan Cheng
Yanxin Lu
Qiang Xia
Zhiyong Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1718894

550 views

Original Research

Published on 16 Jan 2026

An integrative algorithm combining HLA epitope registry, PIRCHE-T2, and PIRCHE-B outcomes to improve immunological risk stratification in kidney transplantation

in Alloimmunity and Transplantation

He Zhao
Pramath Kakodkar
Eric Wang
Dan Zhang
Matthias Niemann
Destinie Webster
Twyla Pearce
Ahmed Shoker
Paul Keown
Karen Sherwood

Frontiers in Immunology

doi 10.3389/fimmu.2025.1718506

1,388 views

Case Report

Published on 16 Jan 2026

Late progression of pediatric Kikuchi-Fujimoto disease to systemic lupus erythematosus: a case report and review of literature

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Salma Bessioud
Karima Tlili
Hager Barakizou
Sameh Mezri

Frontiers in Immunology

doi 10.3389/fimmu.2025.1724306

734 views

49,575 articles

articles

Telitacicept versus belimumab in proliferative lupus nephritis

Moving for optimal immunity: the effect of acute high-intensity interval training on phenotype, virus specificity and chemokine receptor expression in human CD8+ T cells

Bio-boosting transplants: a systematic review on biopolymers in vascular composite allotransplantation

Editorial: Roles of macrophages and monocytes in resistance to immunotherapy in cancers

Correction: Interventional effects of mesenchymal stem cells on epithelial-mesenchymal transition in head and neck squamous cell carcinoma and underlying mechanisms: a systematic review and meta-analysis of in vitro studies

Exo-nanomaterials in cancer immunotherapy: reprogramming the tumor immune microenvironment

Oral tolerogenic vaccine combined with gastrin restores immune tolerance and beta-cell function in NOD mice with Type 1 diabetes

Synergistic effects of platelet-rich fibrin and CTLA4Ig gene-transfected porcine skin on accelerating wound healing in a rat model of deep second-degree burns: a mechanistic study

Correction: Promiscuous class II-binding SARS-CoV-2-nuc derived vaccine-peptide induced extensive conventional, innate and unconventional T cell responses

Mechanisms and Therapeutic of Immunometabolic Reprogramming Driving Macrophage-Endothelial Cell Interactions in Sepsis-Associated ARDS from the Gut-Lung Axis Perspective

The Microbial Peace-Signal Hypothesis: A Unified Framework for Lifelong Immune Restraint

Blood-based Epigenetic Biomarkers in Rheumatoid arthritis: Current Knowledge and Future Perspectives

Dynamics of leukocyte populations, immune-regulatory cytokines, and biochemical parameters in wild boar and domestic pigs experimentally infected with a virulent African swine fever virus genotype II strain

FFPE-based Proteomics and Machine Learning Reveal Immune Microenvironment Features and Distant Metastasis Risk in N1c Colorectal Cancer

Association between statin use and the risk of colorectal cancer in patients with inflammatory bowel disease: a systematic review and meta-analysis

Histone lactylation-derived TET2 enhanced Arg1-mediated MDSC immunosuppression

Impact of treatment interruption on the efficacy and safety of vunakizumab in patients with moderate-to-severe plaque psoriasis: a post-hoc analysis of a phase 3 trial

Transpresentation of interleukin 15 by stromal cell subsets regulates immune cell homeostasis

IL-12-armed oncolytic HSV-2 enhances CAR T cell efficacy against pancreatic cancer in xenografted models

Flavin and deazaflavin biosynthesis in mycobacteria: relevance to physiology, implications for drug discovery, MR-1 antigenicity, and vaccine development

Internalization-related host factors of common respiratory viruses

“Brake” and “accelerator”: revisiting tumor cell direct responses and the paradox of aggression in anti-VEGF therapy

An integrative algorithm combining HLA epitope registry, PIRCHE-T2, and PIRCHE-B outcomes to improve immunological risk stratification in kidney transplantation

Late progression of pediatric Kikuchi-Fujimoto disease to systemic lupus erythematosus: a case report and review of literature