Frontiers in Immunology

Review

Accepted on 16 Jan 2026

Blood-based Epigenetic Biomarkers in Rheumatoid arthritis: Current Knowledge and Future Perspectives

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Agnieszka Mołoń
Hubert Kubis
Joanna Żurawska
Marek Cieśla

Frontiers in Immunology

178 views

Original Research

Accepted on 16 Jan 2026

Dynamics of leukocyte populations, immune-regulatory cytokines, and biochemical parameters in wild boar and domestic pigs experimentally infected with a virulent African swine fever virus genotype II strain

in Comparative Immunology

Giulia Franzoni
Fabian Z. X. Lean
Emanuela Giaconi
Giuseppe Tedde
Susanna Zinellu
Paola Nicolussi
Mireille Le Dimna
Marie-Frédérique Le Potier
Elliot Steedman
Helen Rachel Crooke

Frontiers in Immunology

267 views

Original Research

Accepted on 16 Jan 2026

FFPE-based Proteomics and Machine Learning Reveal Immune Microenvironment Features and Distant Metastasis Risk in N1c Colorectal Cancer

in Cancer Immunity and Immunotherapy

Chenxiao Zheng
Qiongying Zhang
Peng Li
Haobo Jin
Hangjia Xu
Yating Zheng
Yanyu Chen
Zihan Wang
Baiwang Zhu
Xiaodong Zhang

Frontiers in Immunology

150 views

Systematic Review

Published on 16 Jan 2026

Association between statin use and the risk of colorectal cancer in patients with inflammatory bowel disease: a systematic review and meta-analysis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Meng Ding
Yang Liu
Ying Zhang
Yunfeng Qiu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1693342

833 views

Original Research

Published on 16 Jan 2026

Histone lactylation-derived TET2 enhanced Arg1-mediated MDSC immunosuppression

in Cancer Immunity and Immunotherapy

Wenxin Da
Yao Dai
Bo Shen
Yan Zhang
Pengtao Bao
Wei Zhu
Deqiang Wang
Shengjun Wang
Jie Ma

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677780

719 views

Review

Published on 16 Jan 2026

Flavin and deazaflavin biosynthesis in mycobacteria: relevance to physiology, implications for drug discovery, MR-1 antigenicity, and vaccine development

in Vaccines and Molecular Therapeutics

Nurudeen Oketade
Melissa D. Chengalroyen
Dylan Kain
David M. Lewinsohn
Karen M. Dobos

Frontiers in Immunology

doi 10.3389/fimmu.2025.1656167

1,162 views

Original Research

Published on 16 Jan 2026

Impact of treatment interruption on the efficacy and safety of vunakizumab in patients with moderate-to-severe plaque psoriasis: a post-hoc analysis of a phase 3 trial

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Qunyan Li
Weifeng Yao
Dongyun Lei
Yan Xu
Litao Zhang
Zuotao Zhao
Junchen He
Tao Guo
Junying Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639049

805 views

Original Research

Published on 16 Jan 2026

Transpresentation of interleukin 15 by stromal cell subsets regulates immune cell homeostasis

in Cytokines and Soluble Mediators in Immunity

Carmen Stecher
Romana Bischl
Elisabeth Potzmann
Anna Schmid-Böse
Stefanie Ferstl
Nina Braun
Ellen R. Richie
Matthias Farlik
Richard A. Flavell
Dietmar Herndler-Brandstetter

Frontiers in Immunology

doi 10.3389/fimmu.2025.1673309

987 views

Original Research

Published on 16 Jan 2026

IL-12-armed oncolytic HSV-2 enhances CAR T cell efficacy against pancreatic cancer in xenografted models

in Cancer Immunity and Immunotherapy

Chongfeng Xu
Jian Wu
Weikang Liu
Xiaoya Zhou
Qian Liang
Guoya Li
Yang Wang
Yanliang Liu
Qiying Cai
Zilong Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1664289

885 views

Original Research

Published on 16 Jan 2026

Sex-specific associations between systemic autoantibodies and allergic sensitization or allergic disease – results from a population-based study

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

J. Linseisen
C. Laichinger
E. Kling
R. Hoffmann
F. Rohm
C. Meisinger

Frontiers in Immunology

doi 10.3389/fimmu.2025.1740193

606 views

Review

Published on 16 Jan 2026

Internalization-related host factors of common respiratory viruses

in Viral Immunology

Qiuchi Lv
Zhengde Xie
Lili Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1724561

710 views

Case Report

Published on 16 Jan 2026

Late progression of pediatric Kikuchi-Fujimoto disease to systemic lupus erythematosus: a case report and review of literature

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Salma Bessioud
Karima Tlili
Hager Barakizou
Sameh Mezri

Frontiers in Immunology

doi 10.3389/fimmu.2025.1724306

758 views

Review

Published on 16 Jan 2026

Fibroblasts as a ruler of the immune microenvironment: measurement and modulation in tissue homeostasis and disease

in Immunological Tolerance and Regulation

Yanling Zhang
Xinyi Fang
Lian Yan
Lin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1752621

835 views

Case Report

Published on 16 Jan 2026

Case Report: Murine typhus complicated by symmetrical peripheral gangrene: first report and diagnostic insights from metagenomic next-generation sequencing

in Microbial Immunology

Hengling Zhu
Linhui Hu
Zaiming Feng
Zichen Zhang
Hengbao Zhu
Huihua Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1746919

539 views

Perspective

Published on 16 Jan 2026

“Brake” and “accelerator”: revisiting tumor cell direct responses and the paradox of aggression in anti-VEGF therapy

in Cancer Immunity and Immunotherapy

Pei Wei
Jiaqi Li
Xueyan Cheng
Yanxin Lu
Qiang Xia
Zhiyong Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1718894

588 views

Original Research

Published on 16 Jan 2026

An integrative algorithm combining HLA epitope registry, PIRCHE-T2, and PIRCHE-B outcomes to improve immunological risk stratification in kidney transplantation

in Alloimmunity and Transplantation

He Zhao
Pramath Kakodkar
Eric Wang
Dan Zhang
Matthias Niemann
Destinie Webster
Twyla Pearce
Ahmed Shoker
Paul Keown
Karen Sherwood

Frontiers in Immunology

doi 10.3389/fimmu.2025.1718506

1,420 views

Original Research

Published on 16 Jan 2026

Sialylation-immune-related lncRNA LINC01605 promotes tumor-infiltrating CD8+ T cell exhaustion and malignancy of clear cell renal cell carcinoma

in Cancer Immunity and Immunotherapy

Ziran Dai
Hao Zhou
Zihao Feng
Mingxiao Zhang
Zheyu Ai
Gaowei Huang
Junjie Cen
Yanping Liang
Jinhuan Wei
Wei Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1744278

786 views

Original Research

Published on 16 Jan 2026

Decoding thymic development: a single-cell atlas of tree shrew immunity

in Antigen Presenting Cell Biology

Haibo Tang
Yunlin He
Lifeng Zhang
Yingying Cao
Baoying Li
Liang Liang
Chengxia Yun
Junyu Tao
Shanshan Zhai
Zhuxin Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1689906

792 views

Original Research

Published on 16 Jan 2026

Protective efficacy of a ‘pan-fungal’ vaccination strategy against experimental Pneumocystis infection in drug-immunosuppressed macaques

in Microbial Immunology

Whitney Rabacal
Anna Hu
Gabrielle Kirton
Taylor I. Chapman
Daniel Wychrij
Kwadwo O. Oworae
Karen A. Norris

Frontiers in Immunology

doi 10.3389/fimmu.2025.1729080

628 views

Systematic Review

Published on 16 Jan 2026

Global research landscape of ferroptosis in gastric cancer: a multidisciplinary bibliometric analysis based on multiple databases (2017-2025)

in Cancer Immunity and Immunotherapy

Nianshan Ji
Yiyao Cheng
Yuheng Peng
Zhiguang Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1726253

926 views

Original Research

Published on 16 Jan 2026

PILRA serves as a diagnostic and prognostic biomarker and modulates the tumor immune microenvironment and immunotherapy response in breast cancer

in Cancer Immunity and Immunotherapy

Bowen Shi
Yan Yang
Lei Xing
Junxia Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1682519

845 views

Editorial

Published on 16 Jan 2026

Editorial: Risk and protective factors in the natural history of autoimmunity

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Christine G. Parks
Esther O. Erdei
Frederick W. Miller

Frontiers in Immunology

doi 10.3389/fimmu.2026.1771091

522 views

Editorial

Published on 16 Jan 2026

Editorial: Interdisciplinary innovations in CAR T-cell therapy for autoimmune and cancer treatment

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Apostolos Zaravinos
Derya Unutmaz
Marko Radic

Frontiers in Immunology

doi 10.3389/fimmu.2026.1780262

645 views

Original Research

Published on 16 Jan 2026

Circulating fibroblasts and neutrophils co-expressing CDH11+ and chemokine receptors in rheumatoid and psoriatic arthritis: a shared mechanism of ‘arthritis spreading’?

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Maria Kyriakidi
Eleni-Kyriaki Vetsika
George E. Fragoulis
Maria Sakkou
Kleio-Maria Verrou
Anastasios Mourikis
Nikolaos I. Vlachogiannis
Maria G. Tektonidou
Petros P. Sfikakis

Frontiers in Immunology

doi 10.3389/fimmu.2025.1743919

1,003 views

49,574 articles

articles

Blood-based Epigenetic Biomarkers in Rheumatoid arthritis: Current Knowledge and Future Perspectives

Dynamics of leukocyte populations, immune-regulatory cytokines, and biochemical parameters in wild boar and domestic pigs experimentally infected with a virulent African swine fever virus genotype II strain

FFPE-based Proteomics and Machine Learning Reveal Immune Microenvironment Features and Distant Metastasis Risk in N1c Colorectal Cancer

Association between statin use and the risk of colorectal cancer in patients with inflammatory bowel disease: a systematic review and meta-analysis

Histone lactylation-derived TET2 enhanced Arg1-mediated MDSC immunosuppression

Flavin and deazaflavin biosynthesis in mycobacteria: relevance to physiology, implications for drug discovery, MR-1 antigenicity, and vaccine development

Impact of treatment interruption on the efficacy and safety of vunakizumab in patients with moderate-to-severe plaque psoriasis: a post-hoc analysis of a phase 3 trial

Transpresentation of interleukin 15 by stromal cell subsets regulates immune cell homeostasis

IL-12-armed oncolytic HSV-2 enhances CAR T cell efficacy against pancreatic cancer in xenografted models

Sex-specific associations between systemic autoantibodies and allergic sensitization or allergic disease – results from a population-based study

Internalization-related host factors of common respiratory viruses

Late progression of pediatric Kikuchi-Fujimoto disease to systemic lupus erythematosus: a case report and review of literature

Fibroblasts as a ruler of the immune microenvironment: measurement and modulation in tissue homeostasis and disease

Case Report: Murine typhus complicated by symmetrical peripheral gangrene: first report and diagnostic insights from metagenomic next-generation sequencing

“Brake” and “accelerator”: revisiting tumor cell direct responses and the paradox of aggression in anti-VEGF therapy

An integrative algorithm combining HLA epitope registry, PIRCHE-T2, and PIRCHE-B outcomes to improve immunological risk stratification in kidney transplantation

Sialylation-immune-related lncRNA LINC01605 promotes tumor-infiltrating CD8+ T cell exhaustion and malignancy of clear cell renal cell carcinoma

Decoding thymic development: a single-cell atlas of tree shrew immunity

Protective efficacy of a ‘pan-fungal’ vaccination strategy against experimental Pneumocystis infection in drug-immunosuppressed macaques

Global research landscape of ferroptosis in gastric cancer: a multidisciplinary bibliometric analysis based on multiple databases (2017-2025)

PILRA serves as a diagnostic and prognostic biomarker and modulates the tumor immune microenvironment and immunotherapy response in breast cancer

Editorial: Risk and protective factors in the natural history of autoimmunity

Editorial: Interdisciplinary innovations in CAR T-cell therapy for autoimmune and cancer treatment

Circulating fibroblasts and neutrophils co-expressing CDH11+ and chemokine receptors in rheumatoid and psoriatic arthritis: a shared mechanism of ‘arthritis spreading’?