Frontiers in Immunology

Review

Published on 16 Jan 2026

Recent advances in human cytomegalovirus: a comprehensive review of pathogenic mechanisms, virus-host interactions, and antiviral strategies

in Viral Immunology

Ying Xia
Ji Zhang
Xiaochuan Shui
Chao Wang
Shuaijie Zhang
Wenqi Chai
Yang Yang
Liang Shen
Chunhua Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1636978

881 views

Original Research

Accepted on 15 Jan 2026

Ensemble Molecular Mimicry correlates with antibody cross-reactivity in proteome-wide studies

in Viral Immunology

James O Wrabl
Vincent J Hilser
Josh Beale
Gabriel Fortunato
Antonieta van den Berg Monsalve

Frontiers in Immunology

210 views

Original Research

Accepted on 15 Jan 2026

Exploring the host-pathogen interaction and genome analysis of multidrug-resistant bacterial pathogen Proteus penneri isolated from Labeo rohita

in Microbial Immunology

Vikash Kumar
Basanta Kumar Das
Suvra Roy
Pratyasha Bhowal
Arpita Roy
Asim Kumar Jana
Jorge Galindo-Villegas

Frontiers in Immunology

240 views

Original Research

Accepted on 15 Jan 2026

Salidroside targets the Notch1/Hes5 axis to reconstruct the molecular innate immune–vascular network and correlates with repair after ischemic stroke

in Molecular Innate Immunity

Jing Zeng
Xiaohua Huang
Jingyi Zeng
Qi Huang
Wenyi Song
Youfeng Xie
Guining Liang
Qingyan Wei
Yating Lan
Donghua Zou

Frontiers in Immunology

208 views

Original Research

Accepted on 15 Jan 2026

Methyl-CpG-binding domain protein 2 epigenetically represses monocyte HLA-DR expression and promotes immune paralysis in HBV-related acute-on-chronic liver failure

in Inflammation

Xiaoqin Liu
Xueyun Zhang
Qiankun Hu
Xueping Yu
Jian Sun
MingQin Lu
Jiming Zhang
Yuxian Huang

Frontiers in Immunology

175 views

Original Research

Accepted on 15 Jan 2026

Possible underdiagnosis of ulcerative colitis in tertiary care can affect medication use and access to healthcare facilities

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Sara Ferraro
Claudia Bartolini
Irma Convertino
Lorenzo Bertani
Francesco Costa
Emiliano Cappello
Olga Paoletti
Sabrina Giometto
Rosa Gini
Ersilia Lucenteforte

Frontiers in Immunology

113 views

Original Research

Accepted on 15 Jan 2026

A rabbit anti-human CD38 antibody for eliminating Daratumumab and Isatuximab interference in immunohematology testing

in Cancer Immunity and Immunotherapy

Liangzi Zhang
Yinze Zhang
Jun Qi
Xiaomin Su
Qinqin Zuo
Fang Yan
Ying Cui
Na Li
Yanying Dong
Hua Xu

Frontiers in Immunology

281 views

Case Report

Published on 15 Jan 2026

EGPA presenting as sudden cardiac arrest: a case report and review of cardiac manifestations

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Huihui Zhang
Miaolin Zhang
Tao Yu
Zhi Zhang
Mengyang Cai
Gang Wang
Weizong Zhang
Huamin Yu
Hong Yuan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1749843

512 views

Review

Published on 15 Jan 2026

Lactylation: the malignant playbook of hepatocellular carcinoma cells and their roadmap to therapy resistance

in Cancer Immunity and Immunotherapy

Shuang Li
Xiaoyu Lu
Lu Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1752404

782 views

Case Report

Published on 15 Jan 2026

Case Report: A successful case of allogeneic stem cell transplantation for pediatric XMEN characterized by neutropenia

in Alloimmunity and Transplantation

Jieyu Tian
Jie Zheng
Maoquan Qin
Huawei Mao
Guanghua Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1687549

674 views

Mini Review

Published on 15 Jan 2026

IL-6/STAT3 signaling in prostate cancer: CAF-driven immune evasion and therapeutic opportunities

in Cancer Immunity and Immunotherapy

Tao Zhou
Yuqi Li
Zhiyu Liu
Zhiqiang Zeng
Tao Li
Li Chen
Huan Zhao
Xiaochun Wu
Yuxuan Shen
Haitao Fan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1736606

723 views

Original Research

Published on 15 Jan 2026

Identifying common genetic etiologies between iridocyclitis and related immune-mediated diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Zhao Liu
Wenqiao Zhang
Qiuyuan Wang
Xumei Du
Zhiqi Tao
Jianguo Huang
Yuqin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1755047

549 views

Case Report

Published on 15 Jan 2026

Case Report: Post-transplant lymphoproliferative disorder after kidney transplantation in a child with schimke immuno-osseous dysplasia

in Primary Immunodeficiencies

Peng Liu
Xiyan Tian
Daokui Ding
Lei Wang
Peile Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1740720

508 views

Review

Published on 15 Jan 2026

cGAS-STING signaling: a therapeutic target in inflammatory bowel disease and related colorectal cancer

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Xi Chen
Xiaohua Tang
Sixuan Chen
Yang Ye
Fei Mao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1709908

623 views

Review

Published on 15 Jan 2026

Hematological complications in solid organ transplant recipients with telomere biology disorders: a narrative review

in Alloimmunity and Transplantation

François M. Carlier
Thomas Planté-Bordeneuve
Antoine Froidure
Carlos Graux
Marie-Astrid van Dievoet
Coline H. M. van Moorsel
Thijs W. Hoffman

Frontiers in Immunology

doi 10.3389/fimmu.2025.1718107

1,005 views

Original Research

Published on 15 Jan 2026

Unveiling the IL-1β/CXCL2 axis: a shared therapeutic target in periodontitis and inflammatory bowel disease

in Mucosal Immunity

Zhongyi Gu
Aichao Gao
Xiang Ma
Xiaotong Wang
Yi Zhang
Yucun Wang
Caiqing Qiu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1728773

717 views

Original Research

Published on 15 Jan 2026

Multi-omics machine learning identifies diagnostic gene signatures and functionally supports PRKACB involvement in macrophage inflammatory responses in sepsis

in Inflammation

Lvying Yang
Sisi Teng
Zengwen Ma
Cunqiao Han
Weiwei Qian

Frontiers in Immunology

doi 10.3389/fimmu.2025.1611348

834 views

Review

Published on 15 Jan 2026

The paradigm shift: re-evaluating preclinical animal models for colorectal cancer in the precision medicine era

in Cancer Immunity and Immunotherapy

Qin Huang
Shucan Wei
Jiahui Yu
Yancen Wu
Hao Lai
Wene Wei
Linhai Yan
Chenlin Su
Wei Shi
Zijie Su

Frontiers in Immunology

doi 10.3389/fimmu.2025.1744692

582 views

Original Research

Published on 15 Jan 2026

SARS-CoV-2 spike antibodies cross-react with dengue virus and enhance infection in vitro and in vivo

in Viral Immunology

Kamini Jakhar
Sudipta Sonar
Gagandeep Singh
Tejeswara Rao Asuru
Garima Joshi
Nisha Beniwal
Tania Sarkar
Mahima Tiwari
Jaskaran Kaur
Deepak Kumar Rathore

Frontiers in Immunology

doi 10.3389/fimmu.2025.1724625

1,888 views

Original Research

Published on 15 Jan 2026

Identification and validation of an endotoxin tolerance–based prognostic model with therapeutic insights in sepsis

in Immunological Tolerance and Regulation

Yu Xie
Yadong Su
Yin Qin
Qiuhong Zhang
Jie Liu
Yanlin Wu
Ning Du
Yu Jiang
Gang Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1707490

840 views

Review

Published on 15 Jan 2026

From ketogenic metabolism to targeted therapeutics: current advances in β-hydroxybutyrylation

in Cancer Immunity and Immunotherapy

Fangshuai Hu
Changming Liang
Xu Zhang
Lishuai Xu
Chengwei Wu
Senlin Wan
Jiawei Wang
Mengyun Wang
Dawei Zhang
Yongchun Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1690224

887 views

Case Report

Published on 15 Jan 2026

Anti-VGLUT2 autoantibodies associated with post-COVID neurocognitive dysfunction: a case report

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Jeyanthan Charles James
Bianca Teegen
Thivya Pakeerathan
Gregor Hütter
Theodoros Ladopoulos
Nadine Siems
Nadine Trampe
Ilya Ayzenberg
Ralf Gold
Simon Faissner

Frontiers in Immunology

doi 10.3389/fimmu.2025.1731744

991 views

Review

Published on 15 Jan 2026

Glutamine metabolism remodels tumor-associated macrophage: mechanistic explorations and new strategies in translational medicine

in Cancer Immunity and Immunotherapy

Juya Cui
Xia Yan
Jianbo Song

Frontiers in Immunology

doi 10.3389/fimmu.2025.1715170

623 views

Original Research

Published on 15 Jan 2026

Identification of biomarkers and construction of discriminating model for tuberculosis patients with diabetes mellitus based on proteomics: a cross-sectional study

in Microbial Immunology

Yufeng Li
Peng Cheng
Yajing An
Ruizi Ni
Zhaoyang Ye
Ling Yang
Li Zhuang
Linsheng Li
Liang Wang
Wenping Gong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1713654

656 views

49,574 articles

articles

Recent advances in human cytomegalovirus: a comprehensive review of pathogenic mechanisms, virus-host interactions, and antiviral strategies

Ensemble Molecular Mimicry correlates with antibody cross-reactivity in proteome-wide studies

Exploring the host-pathogen interaction and genome analysis of multidrug-resistant bacterial pathogen Proteus penneri isolated from Labeo rohita

Salidroside targets the Notch1/Hes5 axis to reconstruct the molecular innate immune–vascular network and correlates with repair after ischemic stroke

Methyl-CpG-binding domain protein 2 epigenetically represses monocyte HLA-DR expression and promotes immune paralysis in HBV-related acute-on-chronic liver failure

Possible underdiagnosis of ulcerative colitis in tertiary care can affect medication use and access to healthcare facilities

A rabbit anti-human CD38 antibody for eliminating Daratumumab and Isatuximab interference in immunohematology testing

EGPA presenting as sudden cardiac arrest: a case report and review of cardiac manifestations

Lactylation: the malignant playbook of hepatocellular carcinoma cells and their roadmap to therapy resistance

Case Report: A successful case of allogeneic stem cell transplantation for pediatric XMEN characterized by neutropenia

IL-6/STAT3 signaling in prostate cancer: CAF-driven immune evasion and therapeutic opportunities

Identifying common genetic etiologies between iridocyclitis and related immune-mediated diseases

Case Report: Post-transplant lymphoproliferative disorder after kidney transplantation in a child with schimke immuno-osseous dysplasia

cGAS-STING signaling: a therapeutic target in inflammatory bowel disease and related colorectal cancer

Hematological complications in solid organ transplant recipients with telomere biology disorders: a narrative review

Unveiling the IL-1β/CXCL2 axis: a shared therapeutic target in periodontitis and inflammatory bowel disease

Multi-omics machine learning identifies diagnostic gene signatures and functionally supports PRKACB involvement in macrophage inflammatory responses in sepsis

The paradigm shift: re-evaluating preclinical animal models for colorectal cancer in the precision medicine era

SARS-CoV-2 spike antibodies cross-react with dengue virus and enhance infection in vitro and in vivo

Identification and validation of an endotoxin tolerance–based prognostic model with therapeutic insights in sepsis

From ketogenic metabolism to targeted therapeutics: current advances in β-hydroxybutyrylation

Anti-VGLUT2 autoantibodies associated with post-COVID neurocognitive dysfunction: a case report

Glutamine metabolism remodels tumor-associated macrophage: mechanistic explorations and new strategies in translational medicine

Identification of biomarkers and construction of discriminating model for tuberculosis patients with diabetes mellitus based on proteomics: a cross-sectional study