Frontiers in Immunology

Case Report

Published on 12 Jan 2026

Case report: Efgartigimod treatment in two pediatric patients with chronic inflammatory demyelinating polyneuropathy

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yanping Ran
Wenlin Wu
Chi Hou
Haixia Zhu
Wenxiao Wu
Zongzong Chen
Xuexia Ma
Xiaolan Mo
Houliang Deng
Yuanyuan Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1741057

692 views

Review

Published on 12 Jan 2026

The tumor microenvironment: adding pieces to the puzzle

in Cancer Immunity and Immunotherapy

Dolores Aguilar-Cazares
Mario Perez-Medina
Jesus J. Benito-Lopez
Miriam Galicia-Velasco
Manuel Meneses-Flores
Angel Camarena
Jose S. Lopez-Gonzalez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1731338

795 views

Original Research

Published on 12 Jan 2026

Postbiotic effects elicited by heat-inactivated Lacticaseibacillus rhamnosus GG against cow’s milk allergy in human cells

in Nutritional Immunology

Franca Oglio
Lorella Paparo
Laura Carucci
Alessia Gaeta
Samantha Armiento
Serena Coppola
Antonio Molinaro
Cristina De Castro
Antonio Masino
Vittoria Mauriello

Frontiers in Immunology

doi 10.3389/fimmu.2025.1671729

810 views

Original Research

Published on 12 Jan 2026

Robust, scalable and xeno-free protocol for differentiating human induced pluripotent stem cells into functional macrophages

in Alloimmunity and Transplantation

Miquel De Homdedeu
Rubén Escribá
Kenia Rodríguez-González
Sergi Querol
Jesus Fernandez-Sojo
Belén Alvarez-Palomo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1719452

934 views

Original Research

Accepted on 09 Jan 2026

Unveiling Potential Diagnostic Biomarkers for Rheumatoid Arthritis Through Integrated Gene Expression Analysis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Feng Zhiwei
yuan fa
guo minggang
chen feng
li wei
yang chenfei

Frontiers in Immunology

930 views

Case Report

Accepted on 09 Jan 2026

Targeted interleukin-6 (IL-6) blockade by siltuximab for cytokine release syndrome control and infection limitation in thirteen patients treated with bi-specific T-cell engagers

in Inflammation

JEANFRANCOIS ROSSI
Thierry Cailleux
Emma Wisnewski
Julie Coussirou
Françoise de Crozals

Frontiers in Immunology

153 views

Original Research

Published on 09 Jan 2026

The role of 5-methylcytosine regulator-related genes in diagnostic and immune regulatory functions in atherosclerosis

in Systems Immunology

Hui Zhao
Ying Kong
Pengfei Ding
Luqun Yang
Ning Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1636323

931 views

Original Research

Published on 09 Jan 2026

Strongyloides stercoralis coinfection impairs immune control of Mycobacterium tuberculosis in TB infected individuals

in Parasite Immunology

Anuradha Rajamanickam
Bindu Dasan
Arul Nancy Pandiarajan
Saravanan Munisankar
Sivakumar Shanmugam
Subash Babu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1735029

815 views

Original Research

Published on 09 Jan 2026

Different Fc scaffolds enhance the breadth of in vitro neutralization of the same Fab against different Rotavirus strains

in Vaccines and Molecular Therapeutics

Mabel Rocio Miranda-Echagüe
Giacomo Vezzani
Elena Morandi
Melania Della Peruta
Mirko Scordio
Teresa Anne Clarisse Reyes
Davide Oldrini
Miren Iturriza-Gómara
Rebecca Jo Loomis
Omar Rossi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1709107

1,007 views

Systematic Review

Published on 09 Jan 2026

Effects of exercise on angiogenesis biomarkers in cancer patients: a systematic review and meta-analysis

in Cancer Immunity and Immunotherapy

Jingyu Wang
Yuxuan He
Ziqian Wang
Zhouluo Wang
Yu Sun
Kyung-Hee Lee
Jae-Young Choi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1705472

839 views

Review

Published on 09 Jan 2026

Lactylation in cancer: mechanistic insights, tumor microenvironment, and therapeutic horizons

in Cancer Immunity and Immunotherapy

Qiang Yang
Zhibo Yang
Hai Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1697008

1,277 views

Original Research

Published on 09 Jan 2026

C-X-C motif chemokine ligand 13 suppresses osteoclast differentiation via interference with RANKL–RANK interaction

in Cytokines and Soluble Mediators in Immunity

Trung-Loc Ho
Kun-Tsan Lee
Yu-Hao He
Le Huynh Hoai Thuong
David Achudhan
Wei-Chien Huang
Chih-Yuan Ko
Chun-Lin Liu
Jeng-Hung Guo
Chih-Hsin Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1729222

1,098 views

Original Research

Published on 09 Jan 2026

Fc-enhanced anti-CCR6 antibody elicits robust therapeutic effects across multiple autoimmune diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Md Jahangir Alam
Yu-Anne Yap
Caroline Ang
Liang Xie
Hillary L. Shane
Charles R. Mackay
Remy Robert

Frontiers in Immunology

doi 10.3389/fimmu.2025.1728419

1,350 views

Original Research

Published on 09 Jan 2026

Cuproptosis-driven reprogramming of fibroblast communication by GK is associated with the immune microenvironment in diabetic foot ulcers

in Systems Immunology

Tianbo Li
Jiangning Wang
Lei Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1687806

999 views

Correction

Published on 09 Jan 2026

Correction: New serum soluble factors predicting inflammatory and non-inflammatory disability worsening in multiple sclerosis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Frontiers Production Office

Frontiers in Immunology

doi 10.3389/fimmu.2025.1774415

334 views

Review

Published on 09 Jan 2026

Modeling the pre-metastatic niche of gastric cancer peritoneal metastasis under spatiotemporal resolution and investigating EVs-mediated immune suppression

in Cancer Immunity and Immunotherapy

Xiang Zhang
Cheng Zhang
Zheng Zhang
Xuan Zhang
Kai Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1734244

1,487 views

Original Research

Published on 09 Jan 2026

ULMnet: inferring physical cell-cell communication networks from scRNAseq data using univariate linear models

in Systems Immunology

Sodiq A. Hameed
Luis Fernando Iglesias-Martinez
Walter Kolch
Vadim Zhernovkov

Frontiers in Immunology

doi 10.3389/fimmu.2025.1722504

1,670 views

Methods

Published on 09 Jan 2026

Making deep immunophenotyping accessible: the successful application of a guided 23-parameter mouse immunophenotyping panel package provided through a shared resource

in Systems Immunology

Madison G. Isbell
Alex Wendling
Xinyan Pei
Amit Kumar
Padmanabhan Mannangatti
Bradley A. Krisanits
Stanley Cheatham
Marie Michenkova
Kirill Shumilov
Rachel G. Mendoza

Frontiers in Immunology

doi 10.3389/fimmu.2025.1668405

1,103 views

Original Research

Published on 09 Jan 2026

Sex-specific and socioeconomic disparities in the global burden of inflammatory bowel disease in 204 countries, 1990–2021: projections to 2050

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Qingtong Li
Yanqi Kou
Mingcheng Zhang
Chunyi Wu
Rongfo Mi
Wantong Jiang
Yufei Cheng
Lei Ge
Ke Yang
Zhe Huang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1673212

827 views

Review

Published on 09 Jan 2026

Engineering neuroimmune regulation: biomaterial and nanotechnology platforms for neuropathology diagnosis and targeted immunomodulation

in Multiple Sclerosis and Neuroimmunology

Mikayla S. Jackson
Lauren G. Porter
Robert S. Oakes

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677612

1,264 views

Review

Published on 09 Jan 2026

Death as rebirth: how efferocytosis drives tissue repair and disease treatment

in Cancer Immunity and Immunotherapy

Xinliang Duan
Sichen Han
Yifu Bian
Yao Yuan
Jiayu Shen
Yixuan Dai
Junzi Mi
Zilin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1712547

1,092 views

Review

Published on 09 Jan 2026

Aberrant B cell responses as drivers of autoantibody generation and epitope diversification in SLE pathogenesis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Fareeha Tariq
Yathavi Charavanmuttu
Kazi Labiba
Chris Wincup

Frontiers in Immunology

doi 10.3389/fimmu.2025.1731285

2,079 views

Original Research

Published on 09 Jan 2026

Targeting the epidermal growth factor receptor using IgM antibodies: toward next generation cancer immunotherapy

in Cancer Immunity and Immunotherapy

Kamolrat Somboon
Peter J. Bond
Firdaus Samsudin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1733907

623 views

Original Research

Published on 09 Jan 2026

The impact of metabolic dysfunction-associated steatotic liver disease on the efficacy of pegylated interferon-based therapy in patients with chronic hepatitis B

in Viral Immunology

Jiaxin Han
Lianxin Xu
Yuqin Li
Ziling Wang
Minghui Zeng
Jieru Gao
Yuqiang Mi
Wentao Kuai
Huiling Xiang
Liang Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1708909

857 views

49,662 articles

articles

Case report: Efgartigimod treatment in two pediatric patients with chronic inflammatory demyelinating polyneuropathy

The tumor microenvironment: adding pieces to the puzzle

Postbiotic effects elicited by heat-inactivated Lacticaseibacillus rhamnosus GG against cow’s milk allergy in human cells

Robust, scalable and xeno-free protocol for differentiating human induced pluripotent stem cells into functional macrophages

Unveiling Potential Diagnostic Biomarkers for Rheumatoid Arthritis Through Integrated Gene Expression Analysis

Targeted interleukin-6 (IL-6) blockade by siltuximab for cytokine release syndrome control and infection limitation in thirteen patients treated with bi-specific T-cell engagers

The role of 5-methylcytosine regulator-related genes in diagnostic and immune regulatory functions in atherosclerosis

Strongyloides stercoralis coinfection impairs immune control of Mycobacterium tuberculosis in TB infected individuals

Different Fc scaffolds enhance the breadth of in vitro neutralization of the same Fab against different Rotavirus strains

Effects of exercise on angiogenesis biomarkers in cancer patients: a systematic review and meta-analysis

Lactylation in cancer: mechanistic insights, tumor microenvironment, and therapeutic horizons

C-X-C motif chemokine ligand 13 suppresses osteoclast differentiation via interference with RANKL–RANK interaction

Fc-enhanced anti-CCR6 antibody elicits robust therapeutic effects across multiple autoimmune diseases

Cuproptosis-driven reprogramming of fibroblast communication by GK is associated with the immune microenvironment in diabetic foot ulcers

Correction: New serum soluble factors predicting inflammatory and non-inflammatory disability worsening in multiple sclerosis

Modeling the pre-metastatic niche of gastric cancer peritoneal metastasis under spatiotemporal resolution and investigating EVs-mediated immune suppression

ULMnet: inferring physical cell-cell communication networks from scRNAseq data using univariate linear models

Making deep immunophenotyping accessible: the successful application of a guided 23-parameter mouse immunophenotyping panel package provided through a shared resource

Sex-specific and socioeconomic disparities in the global burden of inflammatory bowel disease in 204 countries, 1990–2021: projections to 2050

Engineering neuroimmune regulation: biomaterial and nanotechnology platforms for neuropathology diagnosis and targeted immunomodulation

Death as rebirth: how efferocytosis drives tissue repair and disease treatment

Aberrant B cell responses as drivers of autoantibody generation and epitope diversification in SLE pathogenesis

Targeting the epidermal growth factor receptor using IgM antibodies: toward next generation cancer immunotherapy

The impact of metabolic dysfunction-associated steatotic liver disease on the efficacy of pegylated interferon-based therapy in patients with chronic hepatitis B