Frontiers in Immunology

Original Research

Accepted on 16 Apr 2025

Granulomatous Lymphocytic Interstitial Lung Disease (GLILD) in Common Variable Immune Deficiency (CVID): an in-depth clinical, immunological, functional and radiological exploration with a focus on its management, challenged by chronic CMV infection

in Primary Immunodeficiencies

Mattia Moratti
Gioacchino Schifino
Francesco Baccelli
Simona Ferrari
Elisabetta Magrini
Mirna Bassi
Aldo Guerrieri
Maurizio Zompatori
Marcello Lanari
Francesca Conti

Frontiers in Immunology

doi 10.3389/fimmu.2025.1589052

Original Research

Accepted on 16 Apr 2025

Investigation of potential protein biomarkers for the screening of placental-mediated fetal growth restriction disorders using targeted proteomics Olink technology

in Immunological Tolerance and Regulation

Xinyao Zhou
Wuqian Wang
Luan Chen
Yingjun Yang
Xing Wei
Jia Zhou
Kuan Sun
Jianjun Zhu
Xiaofang Sun
Shengying Qin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1542034

Original Research

Accepted on 16 Apr 2025

Multi-omics analysis and experiments uncover the link between cancer intrinsic drivers, stemness, and immunotherapy in ovarian cancer with validation in a pan-cancer census

in Cancer Immunity and Immunotherapy

Yilin Li
Cen chen
Xiaoyu Ji
Ningxiao Jiang
Fei Wang
Xiangqian Gao
Weiwei Chen
Qiang Tang
Yan Li
Shinan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549656

Editorial

Accepted on 16 Apr 2025

Editorial: The immunological events of macrophages in the course of sepsis

in Cytokines and Soluble Mediators in Immunity

Xu Li
Shiyun Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610868

Original Research

Accepted on 16 Apr 2025

Hazards of Lunar Surface Exploration: Determining the Immunogenicity/Allergenicity of Lunar dust

in Inflammation

Audrie Ann Colorado
Cody L Gutierrez
Mayra Nelman-Gonzalez
Gailen D Marshall
J Torin Mccoy
Brian Crucian

Frontiers in Immunology

doi 10.3389/fimmu.2025.1539163

Original Research

Published on 16 Apr 2025

Dual targeting of EZH2 and PD-L1 in Burkitt’s lymphoma enhances immune activation and induces apoptotic pathway

in Cancer Immunity and Immunotherapy

Yurim Jeong
Hyewon Jang
Se Been Kim
Minseo Yu
Ra Eun Kim
Wan-Su Choi
Youngwoo Jeon
Jung-Yeon Lim

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578665

178 views

Original Research

Published on 16 Apr 2025

The role of the LncRNA XIST/miR-15a-5p/MN1 signaling axis in gender disparities in bladder cancer prognosis

in Cancer Immunity and Immunotherapy

Fangzhen Cai
Siwei Xu
Yinan Li
Qingliu He
Qingfu Su
Heyi Chen
Weihui Liu
Jiabi Chen
Qingshui Wang
Yehuda G. Assaraf

Frontiers in Immunology

doi 10.3389/fimmu.2025.1554829

180 views

Case Report

Published on 16 Apr 2025

First-line anti-BCMA CAR-T cell therapy in a fragile patient with biclonal gammopathy and giant plasma cell tumor multiple myeloma with multiple comorbidities: a case report

in Cancer Immunity and Immunotherapy

Yi Fang
Weiwei Lin
Lijing Shen
Beiwen Ni
Minyue Zhang
Yongmei Cai
Yi Zhou
Jian Hou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1564774

215 views

Review

Published on 16 Apr 2025

Treatments and cancer: implications for radiologists

in Cancer Immunity and Immunotherapy

Vincenza Granata
Roberta Fusco
Sergio Venanzio Setola
Assunta Borzacchiello
Francesca Della Sala
Ivano Rossi
Ludovica Ravo
Domenico Albano
Angelo Vanzulli
Antonella Petrillo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1564909

276 views

Original Research

Published on 16 Apr 2025

Clinical characteristics and risk factors of late-stage lung adenocarcinoma patients with bacterial pulmonary infection and its relationship with cellular immune function

in Cancer Immunity and Immunotherapy

Kangli Yang
Haiting Wei
Weiwei Zhu
Yapeng Xu
Shuaifeng Wang
Feifei Fan
Kai Zhang
Qing Yuan
Hongmin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1559211

156 views

Original Research

Published on 16 Apr 2025

Neutrophil-to-lymphocyte ratio predicts a poor prognosis for penile cancer with an immunosuppressive tumor microenvironment

in Cancer Immunity and Immunotherapy

Xingliang Tan
Yanjun Wang
Yiqi Yu
Runhao Zheng
Jing Li
Shaohua Chen
Qingling Xie
Shengjie Guo
Chichen Zhang
Xinpei Deng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568825

253 views

Original Research

Published on 16 Apr 2025

Isolation of human monoclonal antibodies from 4CMenB vaccinees reveals PorB and LOS as the main OMV components inducing cross-strain protection

in Vaccines and Molecular Therapeutics

Giacomo Vezzani
Viola Viviani
Martina Audagnotto
Alessandro Rossi
Paolo Cinelli
Nicola Pacchiani
Chiara Limongi
Laura Santini
Fabiola Giusti
Sara Tomei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1565862

531 views

Original Research

Published on 16 Apr 2025

Increasing donor kidney age significantly aggravates the negative effect of pretransplant donor-specific anti-HLA antibodies on kidney graft survival

in Alloimmunity and Transplantation

Michiel G. H. Betjes
Judith A. Kal-van Gestel
Dave Roelen
Marcia M. L. Kho
Sebastian Heidt
Annelies E. de Weerd
Jacqueline van de Wetering

Frontiers in Immunology

doi 10.3389/fimmu.2025.1574324

205 views

Original Research

Published on 16 Apr 2025

The Lung Cancer Immune Prognostic Score predicts pathologic complete response and survival in NSCLC patients receiving neoadjuvant immunochemotherapy

in Cancer Immunity and Immunotherapy

Yuyan Xie
Zhihao Shi
Tong Chen
Hongyan Li
Menglin Fan
Xuqin Xiang
Fang Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567565

267 views

Review

Published on 16 Apr 2025

The role of circular RNA in immune response to tuberculosis and its potential as a biomarker and therapeutic target

in Microbial Immunology

Mingyang Hong
Xu Huang
Huiming Zhu
Jiahui Ma
Feng Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1542686

207 views

Original Research

Published on 16 Apr 2025

SARS-CoV-2 post-acute sequelae linked to inflammation via extracellular vesicles

in Inflammation

Sara Bachiller
Joana Vitallé
Lluís Camprubí-Ferrer
Manuel García
Isabel Gallego
Marina López-García
María Isabel Galvá
Julio Cañizares
Inmaculada Rivas-Jeremías
María Díaz-Mateos

Frontiers in Immunology

doi 10.3389/fimmu.2025.1501666

398 views