Frontiers in Immunology

Review

Published on 17 Dec 2025

Keratinocytes as active regulators of cutaneous and mucosal immunity: a systematic review across inflammatory epithelial disorders

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Felix J. Klimitz
Yizhuo Shen
Federico Repetto
Stav Brown
Leonard Knoedler
Christine J. Ko
Nebal Abu Hussein
William J. Crisler
Taylor Adams
Naftali Kaminski

Frontiers in Immunology

doi 10.3389/fimmu.2025.1694066

3,592 views

Review

Published on 17 Dec 2025

Nanocarrier-based delivery of siRNA therapeutics in rheumatoid arthritis: immune mechanisms and translational perspectives

in Inflammation

Longbin Bai
Peng Su

Frontiers in Immunology

doi 10.3389/fimmu.2025.1718256

2,094 views

Review

Published on 17 Dec 2025

Ferroptosis in human reproductive tract infections and associated disorders: mechanisms and emerging therapeutic opportunities

in Microbial Immunology

Xinchen Wan
Xue Wang
Yanjun Liu
Longyan Hong
Zhandi Zhao
Pengbo Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1713074

2,426 views

Original Research

Published on 17 Dec 2025

Early intrathecal dexamethasone and methotrexate as an effective approach for immune effector cell-associated neurotoxicity syndrome after CAR-T cell therapies

in Cancer Immunity and Immunotherapy

Juanxia Meng
Hairong Lyu
Zhao Wang
Xue Bai
Haibo Zhu
Yedi Pu
Xiaoyuan He
Xia Xiao
Mingfeng Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1716317

1,896 views

Original Research

Published on 17 Dec 2025

A multidimensional data-driven approach to surgical plan optimization and postoperative residual tumor prediction in ovarian cancer

in Cancer Immunity and Immunotherapy

Lin Yang
Tianhui He
Ping Yu
Chunliang Shang
Jing Wang
Qinkun Sun
Yi Xie
Jianling Yang
Hongyan Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1705428

1,208 views

Original Research

Published on 17 Dec 2025

Prognostic significance of hematological parameters and albumin in BCMA-targeted CAR-T therapy for multiple myeloma

in Cancer Immunity and Immunotherapy

Liansheng Jiang
Hefei Ren
Zhiqing Ke
Yaoting Liu
Chang Liu
Lin Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1703394

1,436 views

Review

Published on 17 Dec 2025

PANoptosis: a potential target of cardiomyopathy

in Inflammation

Mingli Sun
Changxu Lu
Jinwen Wei
Can Gao
Dan Dong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1704465

1,118 views

Review

Published on 17 Dec 2025

CD147 at the crossroads of glycoprotein networks, metabolic reprogramming, and metastatic progression

in Cancer Immunity and Immunotherapy

Tz-Syuan Su
Jiunn-Wei Wang
Yu-Li Su
Ming-Hong Lin
Hsin-Ying Clair Chiou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1727125

1,908 views

Mini Review

Published on 17 Dec 2025

Targeting glioma-associated microglia and macrophages: a new frontier in glioblastoma immunotherapy

in Cancer Immunity and Immunotherapy

Bingyang Wang
Cong Li
Jiatong Gu
Xiaojie Wang
Mingjuan Xun
Bin Jiang
Jun Yan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1726440

2,452 views
1 citation

Review

Published on 17 Dec 2025

Targeting persistently activated inflammatory microenvironment to promote chronic wound healing

in Inflammation

Yuxuan Dai
Yu Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1708358

2,033 views

Original Research

Published on 17 Dec 2025

Unveiling novel therapeutic mechanisms of Xinfeng capsule: modulating the ALKBH5–m6A–LINC00968 axis to alleviate oxidative stress-driven NETosis in rheumatoid arthritis

in Inflammation

Yue Sun
Yang Li
Jian Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1707663

1,600 views

Original Research

Published on 17 Dec 2025

Tumor intrinsic properties dictate Fc receptor expression and cancer cachexia associated increase in checkpoint inhibitor clearance

in Cancer Immunity and Immunotherapy

Bryan C. Remaily
Greg Young
Hannah Lathrop
Justin Thomas
Kyeongmin Kim
Trang T. Vu
Adeoluwa Adeluola
Camille Stanton
Gillian Mulcahy
Zhiliang Xie

Frontiers in Immunology

doi 10.3389/fimmu.2025.1669979

2,308 views

Perspective

Published on 17 Dec 2025

Microbiota and antibiotic exposure in sarcoidosis

in Microbial Immunology

Claudio Ucciferri
Livia Moffa
Claudio Tana

Frontiers in Immunology

doi 10.3389/fimmu.2025.1737273

1,422 views

Original Research

Published on 17 Dec 2025

Commiphora myrrha extract protects pigeons from Eimeria labbeana-like-triggered inflammatory dysregulation

in Parasite Immunology

Rewaida Abdel-Gaber
Shurug Albasyouni
Simeon Santourlidis
Saleh Al Quraishy
Esam Al-Shaebi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1714313

1,153 views

Original Research

Published on 17 Dec 2025

ATF4 promotes renal tubulointerstitial fibrosis through hexokinase II-mediated glycolysis

in Inflammation

Songtao Feng
Yueming Gao
Zheng Wang
Weijie Ni
Yan Zhou
Mingyue Yuan
Jinyang Ge
Lu Sun
Bicheng Liu
Hui Qian

Frontiers in Immunology

doi 10.3389/fimmu.2025.1683249

1,445 views

Case Report

Published on 17 Dec 2025

Case Report: Novel variants in the MYD88 gene (c.104T>C, c.141G>C) in a patient with recurrent abscesses as a cause of type 68 immunodeficiency

in Primary Immunodeficiencies

Anastasiia A. Buianova
Artem A. Ivanov
Vera A. Belova
Alina F. Samitova
Tatiana V. Kulichenko
Iuliia A. Vasiliadis
Dmitriy O. Korostin
Yulia S. Lashkova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1683892

1,305 views

Perspective

Published on 17 Dec 2025

Are they eosinophil extracellular traps?

in Inflammation

Pedro Chacón
Adrián López-Postigo
Javier Monteseirín
David Ribas-Pérez
Antonio Vega-Rioja

Frontiers in Immunology

doi 10.3389/fimmu.2025.1686316

1,107 views

Original Research

Published on 17 Dec 2025

Integrated bioinformatics and machine learning reveal pan-apoptosis and immune infiltration signatures in diabetic nephropathy

in Comparative Immunology

Yu Liu
Wenqian Lu
Zhicong Xiang
Yuli Shen
Baoyi Ni
Hequn Zou
Xiaofei Shao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1659065

2,643 views
1 citation

Mini Review

Published on 17 Dec 2025

Mapping immune trajectories from Helicobacter pylori gastritis to gastric cancer

in Inflammation

Yi Song
Jie Qiu
Jingyue Wu
Wenqi Liu
Qiang Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1693004

1,635 views

Review

Published on 17 Dec 2025

Remodeling the tumor microenvironment: regulatory effects of β-sitosterol and luteolin on the immunosuppressive milieu in endometrial carcinoma and implications for combinatorial immunotherapy

in Cancer Immunity and Immunotherapy

Guojie Ji
Pengbo Wang
Zhihong Kong
Xiangxiang Cao
Xiaowei Shi
Huigen Feng
Huanhuan Hu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1669606

2,870 views

Review

Published on 17 Dec 2025

Getting into host’s skin: initial immune response to Schistosoma mansoni infection

in Parasite Immunology

Carolina Melo Orrico-Ferreira
Paulo Emilio Oliveira Cruz
Joao Vitor Borges Rios
Wellington da Silva Rosa
Beatriz de Souza Santos
Raphael Chagas Silva
Carina Silva Pinheiro
Barbara Castro-Pimentel Figueiredo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661465

1,783 views

Correction

Published on 17 Dec 2025

Correction: Coexistence of bullous pemphigoid, intrahepatic cholangiocarcinoma, and alopecia areata: a case report of multifactorial autoimmunity in a surgical context

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Shanlin Li
Ying Wang
Dingquan Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1765423

841 views

Review

Published on 17 Dec 2025

Human papillomavirus infection and vaccination with thyroid diseases: mechanistic links and immunological insights

in Viral Immunology

Zhengda Wang
Xiwen Chang
Xianbin Cheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1732358

1,287 views

Original Research

Published on 17 Dec 2025

Chronic opioid use is associated with higher antibody response to influenza vaccination in people living with HIV

in Vaccines and Molecular Therapeutics

Christine M. Dang
C. Mindy Nelson
Rajendra N. Pahwa
Hansel E. Tookes
Daniel J. Feaster
Prabhsimran Singh
Allan E. Rodriguez
David W. Forrest
Nobuyo Nakamura
Priya P. Ghanta

Frontiers in Immunology

doi 10.3389/fimmu.2025.1686103

1,439 views

49,797 articles

articles

Keratinocytes as active regulators of cutaneous and mucosal immunity: a systematic review across inflammatory epithelial disorders

Nanocarrier-based delivery of siRNA therapeutics in rheumatoid arthritis: immune mechanisms and translational perspectives

Ferroptosis in human reproductive tract infections and associated disorders: mechanisms and emerging therapeutic opportunities

Early intrathecal dexamethasone and methotrexate as an effective approach for immune effector cell-associated neurotoxicity syndrome after CAR-T cell therapies

A multidimensional data-driven approach to surgical plan optimization and postoperative residual tumor prediction in ovarian cancer

Prognostic significance of hematological parameters and albumin in BCMA-targeted CAR-T therapy for multiple myeloma

PANoptosis: a potential target of cardiomyopathy

CD147 at the crossroads of glycoprotein networks, metabolic reprogramming, and metastatic progression

Targeting glioma-associated microglia and macrophages: a new frontier in glioblastoma immunotherapy

Targeting persistently activated inflammatory microenvironment to promote chronic wound healing

Unveiling novel therapeutic mechanisms of Xinfeng capsule: modulating the ALKBH5–m6A–LINC00968 axis to alleviate oxidative stress-driven NETosis in rheumatoid arthritis

Tumor intrinsic properties dictate Fc receptor expression and cancer cachexia associated increase in checkpoint inhibitor clearance

Microbiota and antibiotic exposure in sarcoidosis

Commiphora myrrha extract protects pigeons from Eimeria labbeana-like-triggered inflammatory dysregulation

ATF4 promotes renal tubulointerstitial fibrosis through hexokinase II-mediated glycolysis

Case Report: Novel variants in the MYD88 gene (c.104T>C, c.141G>C) in a patient with recurrent abscesses as a cause of type 68 immunodeficiency

Are they eosinophil extracellular traps?

Integrated bioinformatics and machine learning reveal pan-apoptosis and immune infiltration signatures in diabetic nephropathy

Mapping immune trajectories from Helicobacter pylori gastritis to gastric cancer

Remodeling the tumor microenvironment: regulatory effects of β-sitosterol and luteolin on the immunosuppressive milieu in endometrial carcinoma and implications for combinatorial immunotherapy

Getting into host’s skin: initial immune response to Schistosoma mansoni infection

Correction: Coexistence of bullous pemphigoid, intrahepatic cholangiocarcinoma, and alopecia areata: a case report of multifactorial autoimmunity in a surgical context

Human papillomavirus infection and vaccination with thyroid diseases: mechanistic links and immunological insights

Chronic opioid use is associated with higher antibody response to influenza vaccination in people living with HIV