Frontiers in Immunology

Review

Published on 11 Dec 2025

Experimental animal models of acute respiratory distress syndrome: one-hit and two-hit establishment application

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yue Zhao
Xin Li
Yanhua Ou
Xiangran Cai
Weijian Huang
Shuhua He
Sisi Liang
Ning Wang
Linliang Song
Meixia Fang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1649074

1,371 views

Original Research

Published on 11 Dec 2025

Evaluation of programmed cell death ligand-1 expression in primary central nervous system lymphoma using whole-tumor histogram analysis of multiparametric MRI: implications for immunotherapy selection

in Cancer Immunity and Immunotherapy

Xiaofang Zhou
Xiaoli Su
Lan Yu
Feng Wang
Shujie Yu
Feifei Yu
Xiaoye Lin
Yang Song
Dairong Cao
Xingfu Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1676273

828 views

Clinical Trial

Published on 11 Dec 2025

Phase 1 study of chidamide in combination with venetoclax, azacitidine, aclarubicin, cytarabine and G-CSF for refractory/relapsed acute myeloid leukemia: clinical safety, efficacy, and correlative analysis

in Cancer Immunity and Immunotherapy

Yanan Wen
Jingjing Yang
Xiawei Zhang
Qingyang Liu
Wenjing Gao
Lili Dong
Weijia Zhao
Sai Huang
Daihong Liu
Yu Jing

Frontiers in Immunology

doi 10.3389/fimmu.2025.1698710

1,703 views
1 citation

Original Research

Published on 10 Dec 2025

RARS1 inhibits ENO1 ubiquitination and degradation to protect against ferroptosis in hepatocellular carcinoma

in Cancer Immunity and Immunotherapy

Shouge Zang
Jvlong Ma
Lichang Chen
Di Cui
Jiangtao Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1686597

1,599 views

Review

Published on 10 Dec 2025

Mechanistic roles of neutrophil heterogeneity in tumour pathogenesis

in Cancer Immunity and Immunotherapy

Hua Lin
Yutian Liao
Zhonghui Chen
Ye Chen
Yating Chen
Yulin Wang
Zhanfei Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1721090

1,276 views

Review

Published on 10 Dec 2025

Research progress on the induction of immunogenic cell death in tumor immunotherapy using a sonodynamic therapy nanoparticle delivery system

in Cancer Immunity and Immunotherapy

Yang Du
Jiangnan Yang
An Xu
Shuai Chen
Deyuan Fu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1681773

1,885 views

Review

Published on 10 Dec 2025

Progress in the preparation of an active immunization model of anti-N-methyl-D-aspartate receptor encephalitis in animals

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Kuikui Zeng
Yuting Liu
Sai Yang
Lingjuan Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1585353

1,259 views

Original Research

Published on 10 Dec 2025

CXCR4 antagonism corrects neutrophil abnormalities and reduces pneumonia severity in a pharmacological mouse model of CXCR2 loss-of-function-mediated neutropenia

in Primary Immunodeficiencies

Chi Huu Nguyen
Katarina Zmajkovicova
Angelina Sekirnik
Sarah Taplin
Myriam Defontis
Jacob R. Bledsoe
Arthur G. Taveras
Lars Karlsson
Robert Johnson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1658987

2,670 views

Review

Published on 10 Dec 2025

Traditional Chinese medicine as potential adjuvants for tumor vaccines: a review of types, mechanisms, and forms

in Cancer Immunity and Immunotherapy

Yongjia Cui
Lutian Gong
Lei Chang
Wenping Lu
Siqing Zhao
Zhili Zhuo
Xiangyang Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661694

1,653 views

Case Report

Published on 10 Dec 2025

Blastic plasmacytoid dendritic cell neoplasm secondary to acute myeloid leukemia with shared mutations in TET2 and DNMT3A: a case report and literature review

in Cancer Immunity and Immunotherapy

Yao Sun
Yingjie Liu
Na Liu
Xiaohui Zhang
Wenrong Huang
Liangding Hu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1656157

918 views

Original Research

Published on 10 Dec 2025

Health-related quality of life and psychosocial outcomes in long-term survivors treated with immune checkpoint inhibitors: a nationwide multicenter study

in Cancer Immunity and Immunotherapy

Taha Koray Sahin
Fatih Atalah
Bahadir Koylu
Ahmet Oruc
Aydin Acarbay
Akgun Karakok
Sevgi Dogan
Cevat Ilteris Kikili
Görkem Turhan
Gamze Emin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1693295

1,550 views

Original Research

Published on 10 Dec 2025

RPL41 inhibits the proliferation and migration of retinoblastoma through the ARL5B-associated lysosomal trafficking

in Cancer Immunity and Immunotherapy

Ye Li
Tian Zhan
Tianfu Chen
Qianwen Zhong
Sheng Xiao
Aiyuan Wang
Yisheng Jiao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1704080

1,038 views

Original Research

Published on 10 Dec 2025

COL8A1 as a pro-inflammatory mediator bridges immune evasion and therapy resistance in glioma

in Cancer Immunity and Immunotherapy

Jiachong Wang
Jiale Li
Jun Peng
Chunyuan Zhang
Zigui Chen
Changfeng Miao
Chunhai Tang
Qisheng Luo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1727298

1,136 views

Perspective

Published on 10 Dec 2025

Oncolytic virus therapy for osteosarcoma: mechanisms, opportunities, and challenges

in Cancer Immunity and Immunotherapy

Jia-Wen Wang
Xiaolei Ge
Jia-Hui Liu
Xiaoyu Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1724768

1,797 views

Review

Published on 10 Dec 2025

Research progress on the role and mechanism of circadian clock gene PER1 in the occurrence and development of multiple diseases

in Inflammation

Yuxiang Zhao
Yujin Li
Tingting Lu
Xinyue Huang
Kerui Chen
Lina Tan
Lihua Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1715457

1,654 views

Original Research

Published on 10 Dec 2025

Synergistic effects of vedolizumab and JAK 1,2,3 inhibitors in Crohn’s disease: insights from a systems biology and artificial intelligence-based approach

in Systems Immunology

Ignacio Marín-Jiménez
Mónica Sierra-Ausín
Teresa Letosa-Abián
Jesús Aparicio
Carmen Montoto-Otero
Silvia Sánchez-Ramón

Frontiers in Immunology

doi 10.3389/fimmu.2025.1699203

1,716 views

Correction

Published on 10 Dec 2025

Correction: Portfolio analysis of single-cell RNA-sequencing and transcriptomic data unravels immune cells and telomere-related biomarkers in sepsis

in Systems Immunology

Dan Chen
Xiyi Huang
Chun Wang
Cheng Zheng
Yunhao Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1746347

617 views

Review

Published on 10 Dec 2025

The immunoregulatory role of integrins in pulmonary diseases

in Inflammation

Qing Xu
Chao Yang
Wanwen Li
Weiwei Qian
Shiyin Chen
Liqing Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1716118

2,029 views

Systematic Review

Published on 10 Dec 2025

Survival benefits of different immunotherapies for hepatocellular carcinoma: a meta-analysis highlighting age, gender, etiology, and tumor burden

in Cancer Immunity and Immunotherapy

Ming-Cheng Guan
Na Li
Qian Ding
Di Sun
Hao Li
Mei Yang
Lei Hong
Hong Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1713151

2,020 views

Original Research

Published on 10 Dec 2025

Cytokine-driven glycosphingolipid metabolism modulates endoplasmic reticulum calcium homeostasis in primary human renal mesangial cells

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Mariia Stefanenko
Tessa M. Ortiz
Sandra G. Mungaray
Mykhailo Fedoriuk
Oleg Palygin
Stefano Berto
Drew Moore
Tamara K. Nowling

Frontiers in Immunology

doi 10.3389/fimmu.2025.1688916

1,196 views

Original Research

Published on 10 Dec 2025

A novel prognostic signature identifies MFAP4 as a tumor suppressor linking the tumor microenvironment to PI3K/AKT signaling in triple-negative breast cancer

in Cancer Immunity and Immunotherapy

Xiaoqin Yu
Xiaofen Li
Shiping Luo
Chuangui Song

Frontiers in Immunology

doi 10.3389/fimmu.2025.1709141

1,783 views
1 citation

Review

Published on 10 Dec 2025

Glycosylation as a strategic mechanism for measles virus and mumps virus immune evasion

in Vaccines and Molecular Therapeutics

Catalina Galvan
Inna G. Ovsyannikova
Richard B. Kennedy

Frontiers in Immunology

doi 10.3389/fimmu.2025.1716829

1,917 views

Review

Published on 10 Dec 2025

Research progress on the application of nanobodies in immunity and infectious skin diseases

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Liguo Qiu
Fengming Hu
Xiaohua Tao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1705553

1,433 views

Original Research

Published on 10 Dec 2025

Maternal western-style diet alters Kupffer cell proportion leading to metabolic dysfunction-associated steatotic liver disease when challenged with western diet in adulthood

in Nutritional Immunology

Sarah J. Miller
Rachel C. Janssen
Wanke Zhao
Karen R. Jonscher
Hua Zhong
Christa I. DeVette
Jacob E. Friedman
Kurt A. Zimmerman

Frontiers in Immunology

doi 10.3389/fimmu.2025.1698609

1,521 views

49,931 articles

articles

Experimental animal models of acute respiratory distress syndrome: one-hit and two-hit establishment application

Evaluation of programmed cell death ligand-1 expression in primary central nervous system lymphoma using whole-tumor histogram analysis of multiparametric MRI: implications for immunotherapy selection

Phase 1 study of chidamide in combination with venetoclax, azacitidine, aclarubicin, cytarabine and G-CSF for refractory/relapsed acute myeloid leukemia: clinical safety, efficacy, and correlative analysis

RARS1 inhibits ENO1 ubiquitination and degradation to protect against ferroptosis in hepatocellular carcinoma

Mechanistic roles of neutrophil heterogeneity in tumour pathogenesis

Research progress on the induction of immunogenic cell death in tumor immunotherapy using a sonodynamic therapy nanoparticle delivery system

Progress in the preparation of an active immunization model of anti-N-methyl-D-aspartate receptor encephalitis in animals

CXCR4 antagonism corrects neutrophil abnormalities and reduces pneumonia severity in a pharmacological mouse model of CXCR2 loss-of-function-mediated neutropenia

Traditional Chinese medicine as potential adjuvants for tumor vaccines: a review of types, mechanisms, and forms

Blastic plasmacytoid dendritic cell neoplasm secondary to acute myeloid leukemia with shared mutations in TET2 and DNMT3A: a case report and literature review

Health-related quality of life and psychosocial outcomes in long-term survivors treated with immune checkpoint inhibitors: a nationwide multicenter study

RPL41 inhibits the proliferation and migration of retinoblastoma through the ARL5B-associated lysosomal trafficking

COL8A1 as a pro-inflammatory mediator bridges immune evasion and therapy resistance in glioma

Oncolytic virus therapy for osteosarcoma: mechanisms, opportunities, and challenges

Research progress on the role and mechanism of circadian clock gene PER1 in the occurrence and development of multiple diseases

Synergistic effects of vedolizumab and JAK 1,2,3 inhibitors in Crohn’s disease: insights from a systems biology and artificial intelligence-based approach

Correction: Portfolio analysis of single-cell RNA-sequencing and transcriptomic data unravels immune cells and telomere-related biomarkers in sepsis

The immunoregulatory role of integrins in pulmonary diseases

Survival benefits of different immunotherapies for hepatocellular carcinoma: a meta-analysis highlighting age, gender, etiology, and tumor burden

Cytokine-driven glycosphingolipid metabolism modulates endoplasmic reticulum calcium homeostasis in primary human renal mesangial cells

A novel prognostic signature identifies MFAP4 as a tumor suppressor linking the tumor microenvironment to PI3K/AKT signaling in triple-negative breast cancer

Glycosylation as a strategic mechanism for measles virus and mumps virus immune evasion

Research progress on the application of nanobodies in immunity and infectious skin diseases

Maternal western-style diet alters Kupffer cell proportion leading to metabolic dysfunction-associated steatotic liver disease when challenged with western diet in adulthood