Frontiers in Immunology

Original Research

Accepted on 16 Dec 2025

A Novel Non-Invasive Diagnostic Approach Based on Urine and Blood: A Cross-Sectional Study Combining lipoarabinomannan Antigen and interferon-gamma release assay for Active tuberculosis

in Microbial Immunology

Long Cai
Mingzhi Zhu
Tingting Fang
Qianqian Peng
Linshan Dai
Yanqin Shao
Libin Liu

Frontiers in Immunology

Correction

Accepted on 16 Dec 2025

Correction: Case Report: Fecal Microbiota Transplantation via capsules ameliorated clinical outcomes in a patient with Multiple Sclerosis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Luca Masucci
Stefano Bibbò
Flavio De Maio
Fioravante Capone
Gianluca Quaranta
Debora Rondinella
Roberto Rosato
Mauro Minelli
Desy De Lorenzis
MAURIZIO SANGUINETTI

Frontiers in Immunology

151 views

Review

Accepted on 16 Dec 2025

Fibroblast–Immune Crosstalk in Oral Squamous Cell Carcinoma: From Tumor Promotion to Immune Evasion

in Cancer Immunity and Immunotherapy

Xiao Liu
Dandan Wang
Xue Cheng
Yining Ma
Siya Li
Jinhai Deng
Chunyan Qiao

Frontiers in Immunology

Case Report

Accepted on 16 Dec 2025

Sequential Anlotinib and Camrelizumab Combination Therapy Achieves Exceptional Survival in Multi-Driver Mutated, TMB-Low/PD-L1-Low/MSS Pulmonary Sarcomatoid Carcinoma: Case Report and Literature Review

in Cancer Immunity and Immunotherapy

Jun Zhu
Ai Zhu
Li Gang
Lidong Liu
Zi-Ran Gao
Jiayun Liu
Yunfei Ye
Xunzhi Zhu
Yi Li
Hong Chen

Frontiers in Immunology

Review

Accepted on 16 Dec 2025

SLC30 (ZnT) and SLC39 (ZIP) zinc transporter families: From gatekeepers of zinc homeostasis to promoters of tumorigenesis and targets for clinical therapy

in Cancer Immunity and Immunotherapy

Yuqiao Zhou
Guangfa Huang
Mengling Liu
Minghui Zhang
Bowen Wu
Jinke Gu

Frontiers in Immunology

Study Protocol

Accepted on 16 Dec 2025

XELOX Combined With Sintilimab and Hyperbaric Oxygen Therapy for Advanced or Metastatic Gastric/Gastroesophageal Junction Adenocarcinoma: Study Protocol for a Prospective, Single-Arm, Phase Ib/II Clinical Trial

in Cancer Immunity and Immunotherapy

Wenke Li
Pengfei Zhang
Mo Cheng
Wei Jing
Menghui Xu
Dan Li
Sihui Song
Ming Liu
Cheng Huang
Lin Zhu

Frontiers in Immunology

Review

Accepted on 16 Dec 2025

From Innate-Like to Innate: The Next Wave of Off-the-Shelf CAR Immunotherapies

in Cancer Immunity and Immunotherapy

Ying Feng
Zhibo Yang
Yueru Zhou
Ying Liang
Hai Zhao

Frontiers in Immunology

Review

Accepted on 16 Dec 2025

The Immunobiology and Therapeutic potential of Regulatory T Cells in Autoimmune Diseases and Allergic Diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Hao-Tao ZENG
Wen-Wen XIE
Jian-Bin HUANG
Yi-Chi ZHOU
Jing-Yi YUAN
Jia-Xue FENG
Xiaohang Shi
Li Tian
Xian-Hai ZENG
Shu-Qi QIU

Frontiers in Immunology

Review

Accepted on 16 Dec 2025

When viral infections meet the anti-MDA5 antibody-positive dermatomyositis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Shuzi Liu
Zheng Zhao
Yabin Li
Yao Tan
Huabin Tian
Xie Fei

Frontiers in Immunology

Review

Accepted on 16 Dec 2025

The Role of Immune Checkpoint Molecules in Cancers

in Cancer Immunity and Immunotherapy

Meilan Zhang
Junjie Xu
Zhaokuan Zheng
Zhiyun Guo
Hao Wang
Mingqing Zhou
Lewei Zhu
Hailin Tang

Frontiers in Immunology

Review

Accepted on 16 Dec 2025

Macrophage Polarization in Acute Myocardial Infarction: Multidimensional Regulation and Emerging Therapeutic Opportunities

in Inflammation

Zilv Ye
Bo Wang
Zhengdong Wan
Jiawei Guo

Frontiers in Immunology

Editorial

Accepted on 16 Dec 2025

Editorial: Crosstalk in Tumor Microenvironments: Shaping Early Drug and Immunotherapy Strategies

in Cancer Immunity and Immunotherapy

Guendalina Froechlich
Alessandro Arcucci
Emanuele Sasso

Frontiers in Immunology

Original Research

Accepted on 16 Dec 2025

Postbiotic effects elicited by heat inactivated Lacticaseibacillus rhamnosus GG against cow's milk allergy in human cells

in Nutritional Immunology

Franca Oglio
Lorella Paparo
Laura Carucci
Alessia Gaeta
Samantha Armiento
Serena Coppola
Antonio Molinaro
Cristina De Castro
Antonio Masino
Vittoria Mauriello

Frontiers in Immunology

Original Research

Accepted on 16 Dec 2025

The Impact of Metabolic Dysfunction-Associated Steatotic Liver Disease on the Efficacy of Pegylated Interferon-Based Therapy in Patients with Chronic Hepatitis B

in Viral Immunology

Jiaxin Han
Lianxin Xu
Yuqin Li
Ziling Wang
Minghui Zeng
Jieru Gao
Yuqiang Mi
Wentao Kuai
Huiling Xiang
Xu Liang

Frontiers in Immunology

Editorial

Accepted on 16 Dec 2025

Deciphering Cell-Cell Interactions in Triple-Negative Breast Cancer

in Cancer Immunity and Immunotherapy

Yaying Du
Xue Yang
Xingrui Li
Lvyun Zhu

Frontiers in Immunology

132 views

Original Research

Accepted on 16 Dec 2025

Serum Paraoxonase-1 as a Marker of Oxidative Stress and Pulmonary Dysfunction in Sarcoidosis: Association with Disease Activity and Prognostic Potential

in Inflammation

Mine Büşra Bozkürk
Ersin Gunay
Nalan Ogan
Ipek Candemir
Ugurcan Eker
Alpaslan Ozturk

Frontiers in Immunology

Original Research

Accepted on 16 Dec 2025

Extracellular CIRP Augments Inflammation in Acute Kidney Injury via NKG2D-positive Macrophages

in Inflammation

Fangming Zhang
HUI JIN
CHUYI TAN
Ping Wang
Max Brenner

Frontiers in Immunology

Original Research

Accepted on 16 Dec 2025

Unveiling Tumor Senescence-Driven Prognostic Heterogeneity via MALISS in Stage II/III Colorectal Cancer

in Cancer Immunity and Immunotherapy

Xinyu Liu
Bingyao Liu
Yuhao Tong
Xingyu Zhu
Yaodong Sang
Feng Gao
Xiangyun Niu
Youyong Tang
Kang Xu
Hao Chen

Frontiers in Immunology

Original Research

Published on 16 Dec 2025

Real-world retrospective cohort study evaluating the tolerability of immune globulin intravenous 10% (BIVIGAM®)

in Primary Immunodeficiencies

Lucinda J. Van Anglen
Quyen Luu
Kevin P. Rosenbach
Richard F. Herrscher

Frontiers in Immunology

doi 10.3389/fimmu.2025.1687588

222 views

General Commentary

Published on 16 Dec 2025

Commentary: Targeting fibroblast activation protein in rheumatoid arthritis: from molecular imaging to precision therapeutics

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yaoxin Ao
Jiangfeng Lyu
Junxing Yang
Fangjun Xiao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1653274

258 views

Editorial

Published on 16 Dec 2025

Editorial: Macrophages: allies or merciless enemies in musculoskeletal systems

in Molecular Innate Immunity

M. Alaa Terkawi
Ken Kadoya
Tsutomu Endo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1746089

286 views

Correction

Published on 16 Dec 2025

Correction: Obinutuzumab in systemic lupus erythematosus: a real-world experience

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Chunmei Wu
Yinglu Wang
Shenshen Chen
Yanwei Lin
Fang Du
Xiaodong Wang
Sheng Chen
Liangjing Lu
Shuang Ye
Huihua Ding

Frontiers in Immunology

doi 10.3389/fimmu.2025.1764419

281 views

Editorial

Published on 16 Dec 2025

Editorial: The role of bioactive compounds and nutrients in intestinal mucosal immunity, liver and vascular inflammation

in Nutritional Immunology

Fengjie Sun
Zheng Ruan
Tarek Gamal Abedelmaksoud

Frontiers in Immunology

doi 10.3389/fimmu.2025.1762284

412 views

Original Research

Published on 16 Dec 2025

The epidemiology and biologics treatment patterns of juvenile idiopathic arthritis in Taiwan- an 8-year follow-up

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Ya-Chiao Hu
Yun-Lin Huang
Szu-Yu Yiao
Min-Ting Lin
Fang-Ju Lin
Yao-Hsu Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1712103

536 views

48,461 articles

articles

A Novel Non-Invasive Diagnostic Approach Based on Urine and Blood: A Cross-Sectional Study Combining lipoarabinomannan Antigen and interferon-gamma release assay for Active tuberculosis

Correction: Case Report: Fecal Microbiota Transplantation via capsules ameliorated clinical outcomes in a patient with Multiple Sclerosis

Fibroblast–Immune Crosstalk in Oral Squamous Cell Carcinoma: From Tumor Promotion to Immune Evasion

Sequential Anlotinib and Camrelizumab Combination Therapy Achieves Exceptional Survival in Multi-Driver Mutated, TMB-Low/PD-L1-Low/MSS Pulmonary Sarcomatoid Carcinoma: Case Report and Literature Review

SLC30 (ZnT) and SLC39 (ZIP) zinc transporter families: From gatekeepers of zinc homeostasis to promoters of tumorigenesis and targets for clinical therapy

XELOX Combined With Sintilimab and Hyperbaric Oxygen Therapy for Advanced or Metastatic Gastric/Gastroesophageal Junction Adenocarcinoma: Study Protocol for a Prospective, Single-Arm, Phase Ib/II Clinical Trial

From Innate-Like to Innate: The Next Wave of Off-the-Shelf CAR Immunotherapies

The Immunobiology and Therapeutic potential of Regulatory T Cells in Autoimmune Diseases and Allergic Diseases

When viral infections meet the anti-MDA5 antibody-positive dermatomyositis

The Role of Immune Checkpoint Molecules in Cancers

Macrophage Polarization in Acute Myocardial Infarction: Multidimensional Regulation and Emerging Therapeutic Opportunities

Editorial: Crosstalk in Tumor Microenvironments: Shaping Early Drug and Immunotherapy Strategies

Postbiotic effects elicited by heat inactivated Lacticaseibacillus rhamnosus GG against cow's milk allergy in human cells

The Impact of Metabolic Dysfunction-Associated Steatotic Liver Disease on the Efficacy of Pegylated Interferon-Based Therapy in Patients with Chronic Hepatitis B

Deciphering Cell-Cell Interactions in Triple-Negative Breast Cancer

Serum Paraoxonase-1 as a Marker of Oxidative Stress and Pulmonary Dysfunction in Sarcoidosis: Association with Disease Activity and Prognostic Potential

Extracellular CIRP Augments Inflammation in Acute Kidney Injury via NKG2D-positive Macrophages

Unveiling Tumor Senescence-Driven Prognostic Heterogeneity via MALISS in Stage II/III Colorectal Cancer

Real-world retrospective cohort study evaluating the tolerability of immune globulin intravenous 10% (BIVIGAM®)

Commentary: Targeting fibroblast activation protein in rheumatoid arthritis: from molecular imaging to precision therapeutics

Editorial: Macrophages: allies or merciless enemies in musculoskeletal systems

Correction: Obinutuzumab in systemic lupus erythematosus: a real-world experience

Editorial: The role of bioactive compounds and nutrients in intestinal mucosal immunity, liver and vascular inflammation

The epidemiology and biologics treatment patterns of juvenile idiopathic arthritis in Taiwan- an 8-year follow-up