Frontiers in Immunology

Original Research

Published on 05 Dec 2025

Screening and identification of human HPV18VLP neutralizing antibodies from women receiving HPV vaccine

in Cancer Immunity and Immunotherapy

Yaru Gu
Rui Zhang
Wenhao Wang
Jinrui Zhou
Bixia Liu
Yan Zheng
Houyi Zuo
Yexiang Du
Ying Wang
Renjian Hu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1712231

1,204 views

Brief Research Report

Published on 05 Dec 2025

HLA-vaccine transplantations for refractory leukemia: beyond double-unit cord blood

in Alloimmunity and Transplantation

Wing Leung
Michaela Su-Fern Seng
Thi Ngoc Anh Pham
Debbra Chong
Ah Moy Tan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1726216

1,266 views

Original Research

Published on 05 Dec 2025

Novel ubiquitination-related biomarkers for Crohn’s disease identified by multi-omics study and experimental validation

in Inflammation

Jia Hu
Kai Nie
Xiaoyan Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1687606

1,608 views

Original Research

Published on 05 Dec 2025

Azacitidine as maintenance therapy in pediatric de novo acute myeloid leukemia

in Cancer Immunity and Immunotherapy

Chunping Wu
Chunxia Cai
Mei Li
Nainong Li
Yongzhi Zheng
Hao Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1696125

1,432 views

Original Research

Published on 05 Dec 2025

Association of pharmacokinetic biomarkers with early immune recovery following HLA-haploidentical hematopoietic cell transplantation

in Alloimmunity and Transplantation

Guofang Shen
Timothy W. Synold
Shanzay Khan
David A. Horne
Christopher G. Kanakry
Ryotaro Nakamura

Frontiers in Immunology

doi 10.3389/fimmu.2025.1694754

1,396 views

Review

Published on 05 Dec 2025

Viral manipulation of the HLA class I antigen processing and presentation pathway

in Viral Immunology

Dominic S Nolan
Arwen F Altenburg

Frontiers in Immunology

doi 10.3389/fimmu.2025.1694498

1,861 views
1 citation

Original Research

Published on 05 Dec 2025

New serum soluble factors predicting inflammatory and non-inflammatory disability worsening in multiple sclerosis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Alexander Rodero-Romero
María Domínguez-Mozo
Enric Monreal
José M. García-Domínguez
Noelia Villarrubia
José Ignacio Fernández-Velasco
Manuel Comabella
Susana Sainz de la Maza
Haydee Goicochea Briceño
Juan Luís Chico-García

Frontiers in Immunology

doi 10.3389/fimmu.2025.1729500

1,479 views

Review

Published on 05 Dec 2025

SPP1+ macrophages in tumor immunosuppression: mechanisms and therapeutic implications

in Cancer Immunity and Immunotherapy

Juanjuan Wang
Ya Wang
Yuqing Liu
Rongcun Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1711015

3,398 views
2 citations

Mini Review

Published on 05 Dec 2025

Engineering with care: safety assessment platforms for CRISPR-modified natural killer cells

in Cancer Immunity and Immunotherapy

Alieh Fazeli
Evelyn Ullrich
Toni Cathomen
Tobias Bexte

Frontiers in Immunology

doi 10.3389/fimmu.2025.1711414

2,591 views

Original Research

Published on 05 Dec 2025

Proteomics-driven screening of artemisinin-based combination ratios and mechanistic insights into Plasmodium berghei infection in mice

in Parasite Immunology

Liyu Hao
Jianhui Sun
Jianliang Li
Zongyuan Li
Zeyue Yu
Hanhui Huang
Guimin Liu
Zhenru Shen
Hairu Huo
Qili Yuan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1716096

1,422 views

Original Research

Published on 05 Dec 2025

Soluble epoxide hydrolase inhibition preserves alveolar bone in experimental periodontitis with estrogen deficiency

in Inflammation

Charles Ritter
Pedro Silva Pacheco
Lila Batista Trajano Mattos
Mariana Quirino Silveira Soares
Debora Duarte Moreira
Izabel Regina Fischer Rubira-Bullen
Marco Antonio Hungaro Duarte
Jeroen Van Dessel
Bruce D. Hammock
Laura Carbone

Frontiers in Immunology

doi 10.3389/fimmu.2025.1708504

1,282 views

Original Research

Published on 05 Dec 2025

Transcriptome analysis of differences in the infection of African swine fever virus (SY-1 strain) in iPAMs and PAMs

in Viral Immunology

Haiying Mao
Chuxing Cheng
Yong Wang
Wenhui Zhou
Ke Zhang
Yongqi Wang
Lihao Wang
Zhenrui Song
Xiaomei Sun
Yuanfeng Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1692373

1,394 views

Original Research

Published on 05 Dec 2025

Clinical review of adult Henoch–Schönlein purpura and analysis of predictors related to gastrointestinal involvement

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Ao Guo
Yujun Wang
Xiaojuan Nan
Yueshuai Zhang
Ping Liu
Chen Tu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1694532

1,700 views

Original Research

Published on 05 Dec 2025

Harnessing natural feed additives for sustainable production and economics: the role of Thymus vulgaris L. oil as an antimicrobial agent and a growth promoter in improving production and health of broiler chickens

in Nutritional Immunology

Ahmed M. Saied
Adel I. Attia
Fayiz M. Reda
Mohamed S. El-Kholy
Mohammed A. Al-Badwi
Mahmoud Azzam
Alessandro Di Cerbo
Mahmoud Alagawany
Khaled A. El-Tarabily
Ayman G. EL Nagar

Frontiers in Immunology

doi 10.3389/fimmu.2025.1695478

1,049 views

Original Research

Published on 05 Dec 2025

Monocyte–red blood cell crosstalk supports clearance and heme metabolism in sickle cell anemia

in Inflammation

Marina Dorigatti Borges
Matheus Ajeje de Souza
Izabela Felice Paes
Daniela Pinheiro Leonardo
Dulcinéia Martins Albuquerque
Carolina Lanaro
Sara Teresinha Ollala Saad
Renata Sesti-Costa
Fernando Ferreira Costa

Frontiers in Immunology

doi 10.3389/fimmu.2025.1699306

1,125 views

Review

Published on 05 Dec 2025

Beyond oxidative stress: Ferroptosis as a novel orchestrator in neurodegenerative disorders

in Inflammation

Yaqiao Yi
Pu Jia
Peipei Xie
Xiru Peng
Xuan Zhu
Shuting Yin
Yanfang Luo
Ying Deng
Lifei Wan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1683876

3,166 views
1 citation

Review

Published on 05 Dec 2025

Solute carrier protein family: physiological functions, disease associations, and therapeutic potential in immune-related disorders

in Cytokines and Soluble Mediators in Immunity

Peiyan Li
Chen Liu
Yewei Niu
Peitao Wu
Lixuan Liu
Jiamin Jin
Jinfeng Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1671706

1,602 views

Original Research

Published on 05 Dec 2025

IL-1β, TNF-α, and IL-10 reduce cell viability and differentially alter biofilm structure and gene expression levels in Staphylococcus aureus USA 300

in Microbial Immunology

Adriana N. Zavala-Hernández
Christian Salto-Reyes
Alejandro Bravo-Patiño
Víctor M. Baizabal-Aguirre
Juan J. Valdez-Alarcón

Frontiers in Immunology

doi 10.3389/fimmu.2025.1665397

1,289 views
1 citation

Original Research

Published on 05 Dec 2025

Associations of known and newly identified human milk oligosaccharides with infections in early childhood: the Ulm SPATZ health study

in Nutritional Immunology

Linda P. Siziba
Zhuoxin Peng
Marko Mank
Bernd Stahl
John Gonsalves
Deborah Wernecke
Dietrich Rothenbacher
Jon Genuneit

Frontiers in Immunology

doi 10.3389/fimmu.2025.1703579

1,101 views

Review

Published on 05 Dec 2025

The role of interleukin-37 and interleukin-38 in the development and remission of autism spectrum disorder: a comprehensive review of neuroinflammatory mechanisms and potential therapeutic implications

in Cytokines and Soluble Mediators in Immunity

Zakeya Al Rasbi
Hiba Orsud
Sumaya Hasan Zoughbor
Malak Hajar
Abdulla Mahboob
Bassem Sadek

Frontiers in Immunology

doi 10.3389/fimmu.2025.1716197

1,405 views

Review

Published on 05 Dec 2025

Inflammaging: triggers, molecular mechanisms, immunological consequences, sex differences, and cutaneous manifestations

in Inflammation

Ebru Karpuzoglu
Steven D. Holladay
Robert M. Gogal

Frontiers in Immunology

doi 10.3389/fimmu.2025.1704203

3,096 views
1 citation

Original Research

Published on 05 Dec 2025

A multi-omics approach combining causal inference and in vivo validation identifies key protein drivers of alcohol-associated liver disease

in Inflammation

Qingyi Zhou
Xuan Ma
Qianqian Cui
Lei Zhang
Chao Yao
Zilu Zhang
Xiaoli Wang
Liang Chu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1714502

3,789 views

Original Research

Published on 05 Dec 2025

Design and immunogenicity of a quadrivalent mRNA vaccine targeting HSV-2 with comparative evaluation of co-formulated and admixed formulations

in Vaccines and Molecular Therapeutics

Youngran Cho
Chanwoo Lee
Sang-In Park
Yeongjun Kim
Yu-Sun Lee
Seonghyun Lee
Subin Yoon
Gahyun Roh
Dahyeon Ha
Ayoung Oh

Frontiers in Immunology

doi 10.3389/fimmu.2025.1712691

4,615 views

Review

Published on 05 Dec 2025

Targeting ferroptosis: novel therapeutic approaches and intervention strategies for kidney diseases

in Inflammation

Yanfang Luo
Muyang Long
Xueqin Wu
Liuting Zeng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1700004

5,354 views

49,989 articles

articles

Screening and identification of human HPV18VLP neutralizing antibodies from women receiving HPV vaccine

HLA-vaccine transplantations for refractory leukemia: beyond double-unit cord blood

Novel ubiquitination-related biomarkers for Crohn’s disease identified by multi-omics study and experimental validation

Azacitidine as maintenance therapy in pediatric de novo acute myeloid leukemia

Association of pharmacokinetic biomarkers with early immune recovery following HLA-haploidentical hematopoietic cell transplantation

Viral manipulation of the HLA class I antigen processing and presentation pathway

New serum soluble factors predicting inflammatory and non-inflammatory disability worsening in multiple sclerosis

SPP1+ macrophages in tumor immunosuppression: mechanisms and therapeutic implications

Engineering with care: safety assessment platforms for CRISPR-modified natural killer cells

Proteomics-driven screening of artemisinin-based combination ratios and mechanistic insights into Plasmodium berghei infection in mice

Soluble epoxide hydrolase inhibition preserves alveolar bone in experimental periodontitis with estrogen deficiency

Transcriptome analysis of differences in the infection of African swine fever virus (SY-1 strain) in iPAMs and PAMs

Clinical review of adult Henoch–Schönlein purpura and analysis of predictors related to gastrointestinal involvement

Harnessing natural feed additives for sustainable production and economics: the role of Thymus vulgaris L. oil as an antimicrobial agent and a growth promoter in improving production and health of broiler chickens

Monocyte–red blood cell crosstalk supports clearance and heme metabolism in sickle cell anemia

Beyond oxidative stress: Ferroptosis as a novel orchestrator in neurodegenerative disorders

Solute carrier protein family: physiological functions, disease associations, and therapeutic potential in immune-related disorders

IL-1β, TNF-α, and IL-10 reduce cell viability and differentially alter biofilm structure and gene expression levels in Staphylococcus aureus USA 300

Associations of known and newly identified human milk oligosaccharides with infections in early childhood: the Ulm SPATZ health study

The role of interleukin-37 and interleukin-38 in the development and remission of autism spectrum disorder: a comprehensive review of neuroinflammatory mechanisms and potential therapeutic implications

Inflammaging: triggers, molecular mechanisms, immunological consequences, sex differences, and cutaneous manifestations

A multi-omics approach combining causal inference and in vivo validation identifies key protein drivers of alcohol-associated liver disease

Design and immunogenicity of a quadrivalent mRNA vaccine targeting HSV-2 with comparative evaluation of co-formulated and admixed formulations

Targeting ferroptosis: novel therapeutic approaches and intervention strategies for kidney diseases