Frontiers in Immunology

Original Research

Published on 04 Dec 2025

A broadly adaptable protocol for isolating Kupffer cells from non-model species: application to Mastomys natalensis and its susceptibility to Old World mammarenaviruses

in Comparative Immunology

Nicolas Corrales
Katharina Hansen-Kant
Angelika Lander
Joseph B. Prescott

Frontiers in Immunology

doi 10.3389/fimmu.2025.1713374

1,342 views
1 citation

Original Research

Published on 04 Dec 2025

Histone-related gene WDR77 promotes tumor progression through cell cycle regulation in skin cutaneous melanoma

in Cancer Immunity and Immunotherapy

Haoxue Zhang
Ke Tang
Yuyao Liu
Shengxiu Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1611112

1,631 views

Brief Research Report

Published on 04 Dec 2025

TSG-6 expression distinguishes rejected and non-rejected human lung transplants: a retrospective study

in Alloimmunity and Transplantation

Mohammad Afzal Khan
Dong ge Li
Ashling L. Zhang
Alexander S. Krupnick
Christine L. Lau

Frontiers in Immunology

doi 10.3389/fimmu.2025.1685251

1,127 views

Original Research

Published on 04 Dec 2025

CXCL9 and CXCL10 support the exacerbated humoral response in recovered COVID-19 patients who developed acute respiratory distress syndrome by promoting plasma cell differentiation, whereas CXCL9 also induces CD40L and CXCR3 upregulation on T helper cells

in Cytokines and Soluble Mediators in Immunity

Romina Quiroga
Sergio Sanhueza
Catalina Sepúlveda
Bárbara Antilef
Camila Muñoz
Camilo Cabrera
Marco Fraga
Faryd Llerena
Liliana Lamperti
María Inés Barría

Frontiers in Immunology

doi 10.3389/fimmu.2025.1684704

1,985 views

Original Research

Published on 04 Dec 2025

Changes in circulating NK and innate-like T cells in type 1 and type 2 diabetes

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Marina Loguinova
Nikita Sergeev
Margarita Samsonova
Alyona Sorokina
Dmitry Grebennikov
Ivan Golodnikov
Anna Goncharenko
Gennady Bocharov
Dmitry Laptev
Rita Khusainova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1667888

1,774 views
1 citation

Original Research

Published on 04 Dec 2025

Bowman’s capsule rupture and its clinical significance in patients with anti-glomerular basement membrane disease

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Huang Kuang
Cai-xia Lin
Xiao-juan Yu
Zhao Cui
Ming-hui Zhao
Xiao-yu Jia

Frontiers in Immunology

doi 10.3389/fimmu.2025.1655319

1,490 views

Case Report

Published on 04 Dec 2025

Coexistence of anti-neurexin-3α-associated autoimmune encephalitis and systemic lupus erythematosus in an adult patient: a case report

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Huiting Zhang
Ning Kong
Zhimin Liao
Jiawu Fu
Jiangang Pan
Wangtao Zhong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1630292

1,171 views

Systematic Review

Published on 04 Dec 2025

Autoimmune thyroid disease and human health: a systematic review of Mendelian randomization studies

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Peijin Li
Qian Wang
Yan Yang
Zhiguo Ding

Frontiers in Immunology

doi 10.3389/fimmu.2025.1689498

6,215 views

Original Research

Published on 04 Dec 2025

Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages

in Microbial Immunology

Md Shoykot Jahan
Jinlan Yang
Yiyue Tang
Dehui Xiong
Peilei Hu
Xichang Tang
Lijun Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1676204

1,330 views
1 citation

Correction

Published on 04 Dec 2025

Correction: Dietary phosphorus restriction induced phospholipid deficiency, endoplasmic reticulum stress, inflammatory response and gut microbiota disorders in Lateolabrax maculatus

in Comparative Immunology

Zixiang Wu
Jiarong Guo
Kangle Lu
Kai Song
Ling Wang
Ruijuan Ma
Chunxiao Zhang
Xueshan Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1691775

826 views

Review

Published on 04 Dec 2025

Sirtuins and tumor immunity: mechanistic insights, immunotherapy prospects, and therapeutic horizons

in Cancer Immunity and Immunotherapy

Jinning Gu
Shanshan Liu
Wen Xiao
Wei Qu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1700483

2,035 views

Review

Published on 04 Dec 2025

Secondary antibody deficiencies: what’s around the corner?

in Cancer Immunity and Immunotherapy

Gianluca Lagnese
Carla Messuri
Remo Poto
Gilda Varricchi
Giuseppe Spadaro

Frontiers in Immunology

doi 10.3389/fimmu.2025.1672413

1,423 views

Review

Published on 04 Dec 2025

CAR-NK cell for gynecological cancers: immune microenvironment remodeling and immunotherapeutic strategies

in Cancer Immunity and Immunotherapy

Mingyao Huang
Siyang Wang
Huiyan Huang
Linze Li
Tian Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1705354

1,337 views

Original Research

Published on 04 Dec 2025

Clinical characteristics and multimodal imaging insights of coronary involvement in immunoglobulin G4–related disease

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Guan Wang
Yaqi Du
Yun Bai
Yimo Zhou
Shuang Ding
Xinrui Wang
Yibin Xie
Hsin-jung Yang
Debiao Li
Zhaoyang Fan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1685508

1,607 views
1 citation

Original Research

Published on 03 Dec 2025

Administration of 2-deoxy-D-glucose induces pyroptosis in murine breast cancer cells via cAMP/PKA/HK2 to impair tumor survival

in Cancer Immunity and Immunotherapy

Tingting Pan
Shengqi Jin
Wei Gao
Kidong Eom
Jing Dong
Lin Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1724476

1,969 views

Original Research

Published on 03 Dec 2025

Evaluation of anti-tetanus IgG antibody levels and influencing factors in patients undergoing hemodialysis

in Vaccines and Molecular Therapeutics

Metin Özsoy
Hakkı Öztürk
Ayşegül Tuna
Artuner Varlıbaş
Salih Cesur
Altan Aksoy
Aydın Çifci
Mehmet Emin Demir

Frontiers in Immunology

doi 10.3389/fimmu.2025.1678676

1,126 views

Opinion

Published on 03 Dec 2025

Beyond the cut-off: harmonizing kappa free light chain index using likelihood ratios improves the clinical interpretation in the diagnosis of multiple sclerosis

in Multiple Sclerosis and Neuroimmunology

Matthijs Oyaert
Louis Nevejan
Cathérine Dekeyser
Pieter De Kesel
Melissa Cambron
Ludo Vanopdenbosch
Liesbeth Van Hijfte
Guy Laureys
Martine Vercammen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1672662

1,051 views

Original Research

Published on 03 Dec 2025

Restoration of peripheral ILC3s by washed microbiota transplantation improves lipid profiles in hyperlipidemia patients

in Microbial Immunology

Yao-Fei Wei
Yi-Shu Wang
Jia-Yin Song
Hao Wang
Xing-Xiang He
Hao-Jie Zhong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1688070

1,646 views

Original Research

Published on 03 Dec 2025

Peripheral blood tRNA-derived fragments as novel noninvasive biomarkers for diagnosis and prognostic stratification in multiple myeloma

in Cancer Immunity and Immunotherapy

Biyun Yi
Yan Gao
Yanzhao Huang
Kaiyun Guo
Rong Liu
Mengying Zeng
Han Xu
Ming Lei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1650510

1,132 views

Review

Published on 03 Dec 2025

“Dissecting the role of T cell exhaustion in cancer progression: a multifaceted approach“

in Cancer Immunity and Immunotherapy

Xinyang Li
Shiwen Song

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646292

2,182 views

Editorial

Published on 03 Dec 2025

Editorial: Systems immunology and computational omics for transformative medicine

in Systems Immunology

Aaron S. Meyer
Chuangqi Wang
Fan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1746667

1,282 views

Original Research

Published on 03 Dec 2025

CD47 expression in solid tumors correlates with phagocytic tumor-associated macrophage gene signature

in Cancer Immunity and Immunotherapy

Nicholas van Buuren
Mengshu Xu
Yi Zhang
Paola Correa
Shiva Zaboli
Azadeh Madjidi
Christina Moon
Szu-Wen Liu
Ruidong Li
Kai-Hui Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1699237

2,635 views

Original Research

Published on 03 Dec 2025

Single-cell RNA sequencing reveals heterogeneity among AT2 epithelial cells in the lung adenocarcinoma microenvironment

in Cancer Immunity and Immunotherapy

Zimeng Cao
Xuefeng Bai
Jing Li
Jinru Cai
Gang Cao
Yuncai Xiao
Wei Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1735459

1,952 views

Original Research

Published on 03 Dec 2025

Development and validation of a machine learning-driven mitochondrial gene signature for the diagnosis of breast cancer

in Cancer Immunity and Immunotherapy

Siyu Tong
Fei Teng
Weijia Kong
Xuanhe Tian
Dong Guo
Meng Liu
Jian Ren

Frontiers in Immunology

doi 10.3389/fimmu.2025.1712089

2,275 views

49,989 articles

articles

A broadly adaptable protocol for isolating Kupffer cells from non-model species: application to Mastomys natalensis and its susceptibility to Old World mammarenaviruses

Histone-related gene WDR77 promotes tumor progression through cell cycle regulation in skin cutaneous melanoma

TSG-6 expression distinguishes rejected and non-rejected human lung transplants: a retrospective study

CXCL9 and CXCL10 support the exacerbated humoral response in recovered COVID-19 patients who developed acute respiratory distress syndrome by promoting plasma cell differentiation, whereas CXCL9 also induces CD40L and CXCR3 upregulation on T helper cells

Changes in circulating NK and innate-like T cells in type 1 and type 2 diabetes

Bowman’s capsule rupture and its clinical significance in patients with anti-glomerular basement membrane disease

Coexistence of anti-neurexin-3α-associated autoimmune encephalitis and systemic lupus erythematosus in an adult patient: a case report

Autoimmune thyroid disease and human health: a systematic review of Mendelian randomization studies

Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages

Correction: Dietary phosphorus restriction induced phospholipid deficiency, endoplasmic reticulum stress, inflammatory response and gut microbiota disorders in Lateolabrax maculatus

Sirtuins and tumor immunity: mechanistic insights, immunotherapy prospects, and therapeutic horizons

Secondary antibody deficiencies: what’s around the corner?

CAR-NK cell for gynecological cancers: immune microenvironment remodeling and immunotherapeutic strategies

Clinical characteristics and multimodal imaging insights of coronary involvement in immunoglobulin G4–related disease

Administration of 2-deoxy-D-glucose induces pyroptosis in murine breast cancer cells via cAMP/PKA/HK2 to impair tumor survival

Evaluation of anti-tetanus IgG antibody levels and influencing factors in patients undergoing hemodialysis

Beyond the cut-off: harmonizing kappa free light chain index using likelihood ratios improves the clinical interpretation in the diagnosis of multiple sclerosis

Restoration of peripheral ILC3s by washed microbiota transplantation improves lipid profiles in hyperlipidemia patients

Peripheral blood tRNA-derived fragments as novel noninvasive biomarkers for diagnosis and prognostic stratification in multiple myeloma

“Dissecting the role of T cell exhaustion in cancer progression: a multifaceted approach“

Editorial: Systems immunology and computational omics for transformative medicine

CD47 expression in solid tumors correlates with phagocytic tumor-associated macrophage gene signature

Single-cell RNA sequencing reveals heterogeneity among AT2 epithelial cells in the lung adenocarcinoma microenvironment

Development and validation of a machine learning-driven mitochondrial gene signature for the diagnosis of breast cancer