Frontiers in Immunology | Alloimmunity and Transplantation

Original Research

Published on 11 Dec 2025

Tertiary lymphoid structure drives allograft rejection via IFN-γ-JAK-STAT-dependent atypical memory B cell differentiation

in Alloimmunity and Transplantation

Lijie Ma
Shiming Gong
Jianchen Fang
Mingxuan Feng
Zhenzhen Zhan
Qiang Xia

Frontiers in Immunology

doi 10.3389/fimmu.2025.1728290

803 views

Original Research

Accepted on 10 Dec 2025

Risk Factors for Cancer and the Importance of Screening in Adult Recipients of Living-Donor Kidney Transplant

in Alloimmunity and Transplantation

Takahisa Hiramitsu
Yuki Shimamoto
Tomoki Himeno
Yuki Hasegawa
Kenta Futamura
Manabu Okada
Yutaka Matsuoka
Norihiko Goto
Toshihiro Ichimori
Shunji Narumi

Frontiers in Immunology

186 views

Perspective

Published on 10 Dec 2025

Recent progress in pig-to-human kidney xenotransplantation

in Alloimmunity and Transplantation

Pei Tao
Kaiyu Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1735113

856 views

Systematic Review

Accepted on 09 Dec 2025

Bio-Boosting Transplants: A Systematic Review on Biopolymers in Vascular Composite Allotransplantation

in Alloimmunity and Transplantation

Leonard Knoedler
Tobias Niederegger
Thomas Schaschinger
Jakob Fenske
Varun P. A. Murugan
Samuel Knoedler
Max Heiland
Adriana C. Panayi
Gabriel Hundeshagen
Alexandre G. Lellouch

Frontiers in Immunology

179 views

Review

Published on 09 Dec 2025

In vitro derivation of megakaryocytes and platelets from induced pluripotent stem cells: developmental foundations and translational perspectives

in Alloimmunity and Transplantation

Maciej Mazurek
Wojciech Młynarski
Dawid P. Grzela

Frontiers in Immunology

doi 10.3389/fimmu.2025.1720048

877 views

Original Research

Accepted on 08 Dec 2025

LOXL2 labels inflammation-associated myofibroblasts predicting kidney allograft dysfunction and fibrosis

in Alloimmunity and Transplantation

Paula Schütz
Birte Hüchtmann
Veerle Van Marck
Barbara Heitplatz
Carolin Walter
Rebecca Rixen
Hermann Pavenstädt
Stefan Reuter
Konrad Buscher

Frontiers in Immunology

171 views

Original Research

Accepted on 05 Dec 2025

GJA5 and ATP1A1 perturbations recapitulate inflammation-related beat irregularities in iPSC-based atrial myocardium tissue model

in Alloimmunity and Transplantation

Thomas Hutschalik
Albert Dasí
Leto L Riebel
Maury Wiendels
Frederikus Bakker
Lucas J.A.M. Beckers
Koen C. Kriege
Susanne M. Valster
Roland C.M. Vulders
Ozan Özgül

Frontiers in Immunology

341 views

Brief Research Report

Published on 05 Dec 2025

HLA-vaccine transplantations for refractory leukemia: beyond double-unit cord blood

in Alloimmunity and Transplantation

Wing Leung
Michaela Su-Fern Seng
Thi Ngoc Anh Pham
Debbra Chong
Ah Moy Tan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1726216

829 views

Original Research

Published on 05 Dec 2025

Association of pharmacokinetic biomarkers with early immune recovery following HLA-haploidentical hematopoietic cell transplantation

in Alloimmunity and Transplantation

Guofang Shen
Timothy W. Synold
Shanzay Khan
David A. Horne
Christopher G. Kanakry
Ryotaro Nakamura

Frontiers in Immunology

doi 10.3389/fimmu.2025.1694754

803 views

Review

Accepted on 04 Dec 2025

The Application of Genetic Testing Technology in Kidney Transplantation: Precision Matching, Non-Invasive Monitoring and Personalised Management

in Alloimmunity and Transplantation

Ya Long Zhang
Hao Wang
Rui Yan
Kangyu Wang
Jiangwei Man
Li Yang

Frontiers in Immunology

183 views

Brief Research Report

Published on 04 Dec 2025

TSG-6 expression distinguishes rejected and non-rejected human lung transplants: a retrospective study

in Alloimmunity and Transplantation

Mohammad Afzal Khan
Dong ge Li
Ashling L. Zhang
Alexander S. Krupnick
Christine L. Lau

Frontiers in Immunology

doi 10.3389/fimmu.2025.1685251

758 views

Correction

Published on 03 Dec 2025

Correction: Platelet alloimmunization in transfusion-dependent thalassemia patients from Southern China (2014-2023)

in Alloimmunity and Transplantation

Frontiers Production Office

Frontiers in Immunology

doi 10.3389/fimmu.2025.1755852

331 views

Correction

Published on 03 Dec 2025

Correction: Leukocyte dynamics in Cynomolgus monkeys following heterotopic heart allotransplantation under costimulation pathway blockade

in Alloimmunity and Transplantation

Gheorghe Braileanu
Agnes M. Azimzadeh
Tianshu Zhang
Lars Burdorf
Richard N. Pierson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1732897

463 views

Original Research

Published on 02 Dec 2025

Association of HLA-DQA106:01 and DPB105:01:01G alleles with susceptibility to end-stage liver disease with HBV infection in liver transplant recipients from the Zhejiang Han population, China

in Alloimmunity and Transplantation

Genjie Lu
Yanmin He
Yangfang Lu
Wei Chen
Caide Lu
Faming Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1684437

708 views

Brief Research Report

Published on 02 Dec 2025

Daratumumab combined with anti-CD20 therapy in pediatric and adult refractory idiopathic nephrotic syndrome: single-center experience

in Alloimmunity and Transplantation

Hamza Naciri Bennani
Thomas Sandaye
Quentin Charroyer
Aurelie Etangsale
Henri Vacher Coponat
Marie Julien
Vincent Mear
Olivier Dunand
Ludovic Di Ascia

Frontiers in Immunology

doi 10.3389/fimmu.2025.1722023

830 views

Review

Published on 28 Nov 2025

Effects of heavy metal exposure on kidney transplant recipients: mechanisms and clinical implications for graft failure risk

in Alloimmunity and Transplantation

Shuxin Li
Hongliang Cao
Binbin Wang
Gengchen Huang
Yongliang Qu
Bo Yuan
Wei Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1718695

862 views

Editorial

Published on 28 Nov 2025

Editorial: Finding new hope in old treatments: repurposing immunotherapy in transplantation

in Alloimmunity and Transplantation

Yeqi Nian
Jasper Iske
Xiaodong Yuan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1738636

644 views

Original Research

Published on 28 Nov 2025

Donor age as an independent predictor of inferior outcomes after haploidentical hematopoietic cell transplantation in acute myeloid leukemia. Study conducted on behalf of GETH-TC

in Alloimmunity and Transplantation

Daniel Munárriz
Estefanía Pérez-López
Carlos Martín Rodríguez
Marta Luque
Albert Esquirol
Carmen Martín Calvo
Clara Aparicio
Felipe Peña-Muñóz
Inmaculada Heras Fernando
Itziar Oiartzabal Ormtegi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1700463

813 views

Editorial

Published on 21 Nov 2025

Editorial: Multi-omics assessment for the discovery of promising novel molecules in the treatment of transplant organ injury

in Alloimmunity and Transplantation

Hao Liu
Xiao-kang Li
Shao-wei Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1744256

515 views

Correction

Published on 21 Nov 2025

Correction: Single-cell transcriptomics unravels the early immune landscape of renal allograft rejection and nominates Ccl3-Ccr5 as a therapeutic target

in Alloimmunity and Transplantation

Fanchao Wei
Zhaoxiang Wang
Ruochen Qi
Jingliang Zhang
Shichao Han
Changhong Shi
Tong Lu
Zhite Zhao
Zhengxuan Li
Lang Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1740964

842 views

Original Research

Published on 18 Nov 2025

Allogeneic hematopoietic stem cell transplantation for mixed-phenotype acute leukemia: a single-center study

in Alloimmunity and Transplantation

Mengze Hao
Xiaoli Zhao
Xiaoyu Zhang
Weihua Zhai
Qiaoling Ma
Donglin Yang
Aiming Pang
Sizhou Feng
Yi He
Erlie Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1691762

1,207 views

Original Research

Accepted on 11 Nov 2025

Transplanted Gene-Modified Placental Cells Boost FVIII Activity in Pediatric Sheep without Eliciting Immunity, Toxicity, or Adverse Events

in Alloimmunity and Transplantation

Brady Trevisan
Martin Rodriguez
Ritu Ramamurthy
Sunil George
Oluwaseun O. Babatunde
Jacqueline Dizon
Jordan Shields
Shannon Lankford
Denise Schwahn
Michael Gautreaux

Frontiers in Immunology

210 views

Case Report

Published on 10 Nov 2025

Case Report: A novel approach to prevent chronic histiocytic intervillositis and recurrent pregnancy loss by targeting maternal alloimmunity

in Alloimmunity and Transplantation

Mathilde Gavillet
Carole Gengler
Helene Legardeur
Monique Gannagé
Jardena Puder
Lydie Beauport
Alice Panchaud
Samuel Rotman
Denis Comte
David Baud

Frontiers in Immunology

doi 10.3389/fimmu.2025.1693016

1,820 views

Original Research

Accepted on 07 Nov 2025

Allo-HCT with Post-Transplant Cyclophosphamide in Older Adults: Similar Safety and a Viable Option Compared to Younger Adults

in Alloimmunity and Transplantation

Gorka Pinedo Martín
Maria Queralt Salas
Maria Teresa Antonio
Montserrat Rovira
MARIA SUAREZ-LLEDÓ
BERTA SOLE
PAOLA CHARRY
Joan Cid
Miquel Lozano
Alexandra Pedraza

Frontiers in Immunology

249 views

1,824 articles

articles

Tertiary lymphoid structure drives allograft rejection via IFN-γ-JAK-STAT-dependent atypical memory B cell differentiation

Risk Factors for Cancer and the Importance of Screening in Adult Recipients of Living-Donor Kidney Transplant

Recent progress in pig-to-human kidney xenotransplantation

Bio-Boosting Transplants: A Systematic Review on Biopolymers in Vascular Composite Allotransplantation

In vitro derivation of megakaryocytes and platelets from induced pluripotent stem cells: developmental foundations and translational perspectives

LOXL2 labels inflammation-associated myofibroblasts predicting kidney allograft dysfunction and fibrosis

GJA5 and ATP1A1 perturbations recapitulate inflammation-related beat irregularities in iPSC-based atrial myocardium tissue model

HLA-vaccine transplantations for refractory leukemia: beyond double-unit cord blood

Association of pharmacokinetic biomarkers with early immune recovery following HLA-haploidentical hematopoietic cell transplantation

The Application of Genetic Testing Technology in Kidney Transplantation: Precision Matching, Non-Invasive Monitoring and Personalised Management

TSG-6 expression distinguishes rejected and non-rejected human lung transplants: a retrospective study

Correction: Platelet alloimmunization in transfusion-dependent thalassemia patients from Southern China (2014-2023)

Correction: Leukocyte dynamics in Cynomolgus monkeys following heterotopic heart allotransplantation under costimulation pathway blockade

Association of HLA-DQA106:01 and DPB105:01:01G alleles with susceptibility to end-stage liver disease with HBV infection in liver transplant recipients from the Zhejiang Han population, China

Daratumumab combined with anti-CD20 therapy in pediatric and adult refractory idiopathic nephrotic syndrome: single-center experience

Effects of heavy metal exposure on kidney transplant recipients: mechanisms and clinical implications for graft failure risk

Editorial: Finding new hope in old treatments: repurposing immunotherapy in transplantation

Donor age as an independent predictor of inferior outcomes after haploidentical hematopoietic cell transplantation in acute myeloid leukemia. Study conducted on behalf of GETH-TC

Editorial: Multi-omics assessment for the discovery of promising novel molecules in the treatment of transplant organ injury

Correction: Single-cell transcriptomics unravels the early immune landscape of renal allograft rejection and nominates Ccl3-Ccr5 as a therapeutic target

Allogeneic hematopoietic stem cell transplantation for mixed-phenotype acute leukemia: a single-center study

Transplanted Gene-Modified Placental Cells Boost FVIII Activity in Pediatric Sheep without Eliciting Immunity, Toxicity, or Adverse Events

Case Report: A novel approach to prevent chronic histiocytic intervillositis and recurrent pregnancy loss by targeting maternal alloimmunity

Allo-HCT with Post-Transplant Cyclophosphamide in Older Adults: Similar Safety and a Viable Option Compared to Younger Adults

articles

Tertiary lymphoid structure drives allograft rejection via IFN-γ-JAK-STAT-dependent atypical memory B cell differentiation

Risk Factors for Cancer and the Importance of Screening in Adult Recipients of Living-Donor Kidney Transplant

Recent progress in pig-to-human kidney xenotransplantation

Bio-Boosting Transplants: A Systematic Review on Biopolymers in Vascular Composite Allotransplantation

In vitro derivation of megakaryocytes and platelets from induced pluripotent stem cells: developmental foundations and translational perspectives

LOXL2 labels inflammation-associated myofibroblasts predicting kidney allograft dysfunction and fibrosis

GJA5 and ATP1A1 perturbations recapitulate inflammation-related beat irregularities in iPSC-based atrial myocardium tissue model

HLA-vaccine transplantations for refractory leukemia: beyond double-unit cord blood

Association of pharmacokinetic biomarkers with early immune recovery following HLA-haploidentical hematopoietic cell transplantation

The Application of Genetic Testing Technology in Kidney Transplantation: Precision Matching, Non-Invasive Monitoring and Personalised Management

TSG-6 expression distinguishes rejected and non-rejected human lung transplants: a retrospective study

Correction: Platelet alloimmunization in transfusion-dependent thalassemia patients from Southern China (2014-2023)

Correction: Leukocyte dynamics in Cynomolgus monkeys following heterotopic heart allotransplantation under costimulation pathway blockade

Association of HLA-DQA1*06:01 and DPB1*05:01:01G alleles with susceptibility to end-stage liver disease with HBV infection in liver transplant recipients from the Zhejiang Han population, China

Daratumumab combined with anti-CD20 therapy in pediatric and adult refractory idiopathic nephrotic syndrome: single-center experience

Effects of heavy metal exposure on kidney transplant recipients: mechanisms and clinical implications for graft failure risk

Editorial: Finding new hope in old treatments: repurposing immunotherapy in transplantation

Donor age as an independent predictor of inferior outcomes after haploidentical hematopoietic cell transplantation in acute myeloid leukemia. Study conducted on behalf of GETH-TC

Editorial: Multi-omics assessment for the discovery of promising novel molecules in the treatment of transplant organ injury

Correction: Single-cell transcriptomics unravels the early immune landscape of renal allograft rejection and nominates Ccl3-Ccr5 as a therapeutic target

Allogeneic hematopoietic stem cell transplantation for mixed-phenotype acute leukemia: a single-center study

Transplanted Gene-Modified Placental Cells Boost FVIII Activity in Pediatric Sheep without Eliciting Immunity, Toxicity, or Adverse Events

Case Report: A novel approach to prevent chronic histiocytic intervillositis and recurrent pregnancy loss by targeting maternal alloimmunity

Allo-HCT with Post-Transplant Cyclophosphamide in Older Adults: Similar Safety and a Viable Option Compared to Younger Adults

Association of HLA-DQA106:01 and DPB105:01:01G alleles with susceptibility to end-stage liver disease with HBV infection in liver transplant recipients from the Zhejiang Han population, China