Frontiers in Immunology | Alloimmunity and Transplantation

Mini Review

Published on 22 Oct 2025

Regulatory T cell therapy in lung transplantation: bridging the gap from bench to bedside

in Alloimmunity and Transplantation

Qianwei Li
Guorui Li
Jinteng Feng
Guangjian Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654561

1,806 views

Original Research

Published on 22 Oct 2025

Single-cell transcriptomics unravels the early immune landscape of renal allograft rejection and nominates Ccl3-Ccr5 as a therapeutic target

in Alloimmunity and Transplantation

Fanchao Wei
Zhaoxiang Wang
Ruochen Qi
Jingliang Zhang
Shichao Han
Changhong Shi
Tong Lu
Zhite Zhao
Zhengxuan Li
Lang Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1663251

2,292 views

Original Research

Published on 16 Oct 2025

Angiotensin II type 1 receptor antibodies as a contributor to microvascular inflammation in kidney transplant recipients: insights from statistical and artificial intelligence based approaches

in Alloimmunity and Transplantation

Jakub Mizera
Piotr Donizy
Agnieszka Halon
Dariusz Janczak
Marta Kepinska
Maciej Pondel
Miroslaw Banasik

Frontiers in Immunology

doi 10.3389/fimmu.2025.1659939

1,437 views

Correction

Published on 14 Oct 2025

Correction: Clinical management and burden of cytomegalovirus in D+/R-Kidney transplant recipients in Canada

in Alloimmunity and Transplantation

John Gill
Andrew A. House
Zain Chagla
Jean Tchervenkov
S. Joseph Kim
Amanda Vinson
Carlos Cervera
Paul A. Keown
Sonia Lai Wing Sun
Christina Khoury

Frontiers in Immunology

doi 10.3389/fimmu.2025.1712602

893 views

Original Research

Published on 13 Oct 2025

Inhibition of CD38 enzyme activity on engrafted human immune cells enhances NAD+ metabolism and inhibits inflammation in an in-vivo model of xeno-GvHD

in Alloimmunity and Transplantation

Ghenima Ahmil-Boiteau
Pranjali Dalvi
Kevin Dang
Harshad S. Ugamraj
Giulia Castello
James Allison
Ute Schellenberger
Roland Buelow
Suhasini Iyer
Ben Buelow

Frontiers in Immunology

doi 10.3389/fimmu.2025.1640611

2,005 views

Original Research

Published on 10 Oct 2025

Leukocyte dynamics in Cynomolgus monkeys following heterotopic heart allotransplantation under costimulation pathway blockade

in Alloimmunity and Transplantation

Gheorghe Braileanu
Agnes M. Azimzadeh
Tianshu Zhang
Lars Burdorf
Richard N. Pierson III

Frontiers in Immunology

doi 10.3389/fimmu.2025.1664463

1,366 views
1 citation

Original Research

Published on 09 Oct 2025

Antibodies to unknown antigens other than swine leukocyte antigens on GTKO/β4GalNT2KO pig cells are associated with AHXR after pig-to-rhesus monkey kidney transplantation

in Alloimmunity and Transplantation

Hongtao Jiang
Haiyun Jiang
Songzhe He
Yuxiang Chen
Jiaxiang Du
Dengke Pan
Tao Li
Yi Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1663702

2,083 views

Original Research

Published on 09 Oct 2025

Identification and characterization of senescent macrophages in renal allograft rejection: a cross-species MultiOmics study

in Alloimmunity and Transplantation

Hanyu Xiao
Jie Zhang
Qidan Pang
Chengjun Yu
Jun Pei
Huyu Wang
Sheng Wen
Chunlan Long
Yi Hua
Guanghui Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1623124

2,477 views

Review

Published on 08 Oct 2025

Research progress in RBC alloimmunization

in Alloimmunity and Transplantation

Zike Fu
Xinxin Hao
Wa Gao
Quishi Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677581

2,875 views
1 citation

Original Research

Published on 03 Oct 2025

Anti-HLA antibodies bound to monocytes altered antibody-mediated platelet phagocytosis and led to mild thrombocytopenia

in Alloimmunity and Transplantation

Xiuzhang Xu
Nelli Baal
Martin Rick
Dawei Chen
Huaqin Liang
Xin Ye
Wenjie Xia
Hui Ren
Yaori Xu
Yongshui Fu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1652134

1,887 views

Brief Research Report

Published on 03 Oct 2025

Platelet alloimmunization in transfusion-dependent thalassemia patients from Southern China (2014-2023)

in Alloimmunity and Transplantation

Yuchen Huang
Yuxi Chen
Qiuhong Mo
Huihui Mo
Fang Lu
Hengcong Li
Lilan Li
Jierun Chen
Lihong Jiang
Yan Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1687913

3,297 views

Original Research

Published on 02 Oct 2025

Visualizing early allograft rejection: an M1 macrophage-specific GLUT1 probe predicts TCMR onset in renal transplantation

in Alloimmunity and Transplantation

Zhaoxiang Wang
Fanchao Wei
Dayuan Huang
Ruochen Qi
Shichao Han
Changhong Shi
Hongtao Song
Yuxuan Du
Zhengxuan Li
Lang Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1670370

2,379 views

Original Research

Published on 02 Oct 2025

Optimizing HLA desensitization: serum dilution strategies and platform-specific MFI thresholds for antibody-mediated rejection risk in kidney transplantation

in Alloimmunity and Transplantation

Dominique Bertrand
Céline Dard
Rangolie Kaveri
Thomas Jouve
Paolo Malvezzi
Lionel Rostaing
Dominique Guerrot
Mathilde Lemoine
Charlotte Laurent
Johan Noble

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661977

3,187 views

Original Research

Published on 02 Oct 2025

Temporal trends in malignancy incidence and outcomes among kidney transplantation recipients: a multi-center real-world evidence study using the TriNetX network (2000–2010 vs. 2010–2021)

in Alloimmunity and Transplantation

Gu-Shun Lai
Jian-Ri Li
Chuan-Shu Chen
Shian-Shiang Wang
Chia-Yen Lin
Che-Jui Yang
Hao-Chung Ho
Sheng-Chun Hung
Kun-Yuan Chiu
Cheng-Kuang Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1626135

2,638 views
1 citation

Review

Published on 01 Oct 2025

Next generation targeted non-genotoxic conditioning for hematopoietic stem cell and hematopoietic stem cell-based gene therapy

in Alloimmunity and Transplantation

Jennifer Okalova
Trent H. Spencer
Shanmuganathan Chandrakasan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1653344

3,460 views

Original Research

Published on 30 Sep 2025

Differentiation of acute versus chronic skin rejection in a rodent model of vascularized composite allotransplantation

in Alloimmunity and Transplantation

Julia Thomé
Maike Lind
Maxime Schmitt
Laura Schneider
Jurij Kiefer
Rebecca Schäfer
Emma Freise
Thierry Christmann
Sheena Kreuzaler
Branislav Kollár

Frontiers in Immunology

doi 10.3389/fimmu.2025.1672754

1,645 views

Systematic Review

Published on 29 Sep 2025

Impact of recent COVID-19 infection on liver and kidney transplantation – a worldwide meta-analysis and systematic review

in Alloimmunity and Transplantation

Nicola Sariye Pollmann
Felix Dondorf
Falk Rauchfuß
Utz Settmacher
Lukas Pollmann
Markus Selzner

Frontiers in Immunology

doi 10.3389/fimmu.2025.1626391

1,978 views

Original Research

Published on 23 Sep 2025

GlyT1 inhibition by ALX-5407 attenuates allograft rejection through suppression of Th1 cell differentiation

in Alloimmunity and Transplantation

Xiaohan Zhang
Weiqi Zhang
Jianghao Wei
Shuai Jin
Zhen Wang
Hui Wang
Gang Feng
Jie Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1644529

2,162 views

Review

Published on 22 Sep 2025

Biochemical markers and emerging therapies for intestinal manifestation of graft-versus-host disease

in Alloimmunity and Transplantation

Katarzyna Wiejak
Adam Przybyłkowski
Agnieszka Tomaszewska

Frontiers in Immunology

doi 10.3389/fimmu.2025.1645503

3,058 views

Original Research

Published on 18 Sep 2025

Clinical management and burden of cytomegalovirus in D+/R-Kidney transplant recipients in Canada

in Alloimmunity and Transplantation

John Gill
Andrew A. House
Zain Chagla
Jean Tchervenkov
S. Joseph Kim
Amanda Vinson
Carlos Cervera
Paul A. Keown
Sonia Lai Wing Sun
Christina Khoury

Frontiers in Immunology

doi 10.3389/fimmu.2025.1618748

2,759 views

Original Research

Published on 17 Sep 2025

Machine learning-based predictive model for the perioperative co-occurrence of T-cell-mediated rejection and pneumonia in liver transplantation

in Alloimmunity and Transplantation

Junjie Sun
Guangyi Zhu
Qingwen Liang
Ning Wen
Haibin Li
Xuyong Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1648993

3,793 views

Original Research

Published on 16 Sep 2025

Identification of HLA-A, HLA-B, and HLA-C triple homozygous and double homozygous donors: a path toward synthetic superdonor advanced therapeutic medicinal products

in Alloimmunity and Transplantation

Daniel Naumovas
Barbara Rojas-Araya
Catalina M. Polanco
Victor Andrade
Rita Čekauskienė
Beatričė Valatkaitė-Rakštienė
Inga Laurinaitytė
Artūras Jakubauskas
Mindaugas Stoškus
Laimonas Griškevičius

Frontiers in Immunology

doi 10.3389/fimmu.2025.1626787

2,059 views

Mini Review

Published on 16 Sep 2025

Mitochondrial transfer/transplantation in lung injury: mechanism, therapeutic potential, and clinical application

in Alloimmunity and Transplantation

Ling-Jie Wang
Peng-Fei Guo
SongOu Zhang
Sai Wang
Yi-Zhao Chen
Hong-Wang Yan
Xue-Lin Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1668281

4,118 views
2 citations

Original Research

Published on 15 Sep 2025

Spatial transcriptomics reveals distinct role of monocytes/macrophages with high FCGR3A expression in kidney transplant rejections

in Alloimmunity and Transplantation

Yan Chen Wongworawat
Chirag Nepal
Mark Duhon
Wanqiu Chen
Minh-Tri Nguyen
Adam Godzik
Xinru Qiu
Wei Vivian Li
Gary Yu
Rafael Villicana

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654741

2,822 views

1,814 articles

articles

Regulatory T cell therapy in lung transplantation: bridging the gap from bench to bedside

Single-cell transcriptomics unravels the early immune landscape of renal allograft rejection and nominates Ccl3-Ccr5 as a therapeutic target

Angiotensin II type 1 receptor antibodies as a contributor to microvascular inflammation in kidney transplant recipients: insights from statistical and artificial intelligence based approaches

Correction: Clinical management and burden of cytomegalovirus in D+/R-Kidney transplant recipients in Canada

Inhibition of CD38 enzyme activity on engrafted human immune cells enhances NAD+ metabolism and inhibits inflammation in an in-vivo model of xeno-GvHD

Leukocyte dynamics in Cynomolgus monkeys following heterotopic heart allotransplantation under costimulation pathway blockade

Antibodies to unknown antigens other than swine leukocyte antigens on GTKO/β4GalNT2KO pig cells are associated with AHXR after pig-to-rhesus monkey kidney transplantation

Identification and characterization of senescent macrophages in renal allograft rejection: a cross-species MultiOmics study

Research progress in RBC alloimmunization

Anti-HLA antibodies bound to monocytes altered antibody-mediated platelet phagocytosis and led to mild thrombocytopenia

Platelet alloimmunization in transfusion-dependent thalassemia patients from Southern China (2014-2023)

Visualizing early allograft rejection: an M1 macrophage-specific GLUT1 probe predicts TCMR onset in renal transplantation

Optimizing HLA desensitization: serum dilution strategies and platform-specific MFI thresholds for antibody-mediated rejection risk in kidney transplantation

Temporal trends in malignancy incidence and outcomes among kidney transplantation recipients: a multi-center real-world evidence study using the TriNetX network (2000–2010 vs. 2010–2021)

Next generation targeted non-genotoxic conditioning for hematopoietic stem cell and hematopoietic stem cell-based gene therapy

Differentiation of acute versus chronic skin rejection in a rodent model of vascularized composite allotransplantation

Impact of recent COVID-19 infection on liver and kidney transplantation – a worldwide meta-analysis and systematic review

GlyT1 inhibition by ALX-5407 attenuates allograft rejection through suppression of Th1 cell differentiation

Biochemical markers and emerging therapies for intestinal manifestation of graft-versus-host disease

Clinical management and burden of cytomegalovirus in D+/R-Kidney transplant recipients in Canada

Machine learning-based predictive model for the perioperative co-occurrence of T-cell-mediated rejection and pneumonia in liver transplantation

Identification of HLA-A, HLA-B, and HLA-C triple homozygous and double homozygous donors: a path toward synthetic superdonor advanced therapeutic medicinal products

Mitochondrial transfer/transplantation in lung injury: mechanism, therapeutic potential, and clinical application

Spatial transcriptomics reveals distinct role of monocytes/macrophages with high FCGR3A expression in kidney transplant rejections