Frontiers in Immunology | Alloimmunity and Transplantation

Original Research

Published on 19 Dec 2025

Lipocalin-2 modulates recipients alloimmune responses to the murine kidney transplants

in Alloimmunity and Transplantation

Anna Maria Pfefferkorn
Raphaela Fritsche-Guenther
Angelika Kusch
Hubert Schwelberger
Shiqian Liu
Robert Klopfleisch
Yuhuan Li
Rusan Catar
Shaokun Liu
Felix Aigner

Frontiers in Immunology

doi 10.3389/fimmu.2025.1716393

2,218 views

Systematic Review

Published on 16 Dec 2025

The efficacy of extracorporeal photopheresis in the treatment of steroid refractory acute graft-versus-host disease: a systematic review and meta-analysis

in Alloimmunity and Transplantation

Zaid Muhanna
Ahmad Issa
Jehad Yasin
Leen Alkuttob
Maya Niss
Muaath Alsufi
Muntaser Al Zyoud
Shatha Farhan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1696862

1,931 views

Original Research

Published on 15 Dec 2025

Epitope-level analysis of cross-reactive human HLA antibodies against genetically modified swine leukocyte antigens in xenotransplantation

in Alloimmunity and Transplantation

Sang-Ik Cho
Ji-Jing Yan
Beom Seok Kim
Nayoung Ko
Joohyun Shim
Hyunil Kim
Eun-Jee Oh

Frontiers in Immunology

doi 10.3389/fimmu.2025.1712793

1,723 views

Original Research

Published on 12 Dec 2025

Long-term compromised immune regulation after rituximab induction in blood group incompatible (ABOi) living-donor renal transplantation – 5 year results of a prospective pilot study

in Alloimmunity and Transplantation

Rolf Weimer
Hristos Karakizlis
Fabrice Renner
Hartmut Dietrich
Volker Daniel
Caner Süsal
Christian Schüttler
Daniel Kämper
Dominik Leicht
Michael Wörlen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1706158

1,316 views

Review

Published on 12 Dec 2025

Urothelial carcinoma following kidney transplantation: a narrative review of Chinese insights and challenges from pathogenesis to precision diagnosis and treatment

in Alloimmunity and Transplantation

Lei Li
Fei Ren
Zhuo Liu
Xiaojun Tian
Hongxian Zhang
Guoliang Wang
Shudong Zhang
Lulin Ma

Frontiers in Immunology

doi 10.3389/fimmu.2025.1668356

1,362 views

Original Research

Published on 11 Dec 2025

Tertiary lymphoid structure drives allograft rejection via IFN-γ-JAK-STAT-dependent atypical memory B cell differentiation

in Alloimmunity and Transplantation

Lijie Ma
Shiming Gong
Jianchen Fang
Mingxuan Feng
Zhenzhen Zhan
Qiang Xia

Frontiers in Immunology

doi 10.3389/fimmu.2025.1728290

1,830 views

Perspective

Published on 10 Dec 2025

Recent progress in pig-to-human kidney xenotransplantation

in Alloimmunity and Transplantation

Pei Tao
Kaiyu Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1735113

2,240 views

Review

Published on 09 Dec 2025

In vitro derivation of megakaryocytes and platelets from induced pluripotent stem cells: developmental foundations and translational perspectives

in Alloimmunity and Transplantation

Maciej Mazurek
Wojciech Młynarski
Dawid P. Grzela

Frontiers in Immunology

doi 10.3389/fimmu.2025.1720048

1,769 views

Original Research

Accepted on 05 Dec 2025

GJA5 and ATP1A1 perturbations recapitulate inflammation-related beat irregularities in iPSC-based atrial myocardium tissue model

in Alloimmunity and Transplantation

Thomas Hutschalik
Albert Dasí
Leto L Riebel
Maury Wiendels
Frederikus Bakker
Lucas J.A.M. Beckers
Koen C. Kriege
Susanne M. Valster
Roland C.M. Vulders
Ozan Özgül

Frontiers in Immunology

558 views

Brief Research Report

Published on 05 Dec 2025

HLA-vaccine transplantations for refractory leukemia: beyond double-unit cord blood

in Alloimmunity and Transplantation

Wing Leung
Michaela Su-Fern Seng
Thi Ngoc Anh Pham
Debbra Chong
Ah Moy Tan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1726216

1,263 views

Original Research

Published on 05 Dec 2025

Association of pharmacokinetic biomarkers with early immune recovery following HLA-haploidentical hematopoietic cell transplantation

in Alloimmunity and Transplantation

Guofang Shen
Timothy W. Synold
Shanzay Khan
David A. Horne
Christopher G. Kanakry
Ryotaro Nakamura

Frontiers in Immunology

doi 10.3389/fimmu.2025.1694754

1,393 views

Brief Research Report

Published on 04 Dec 2025

TSG-6 expression distinguishes rejected and non-rejected human lung transplants: a retrospective study

in Alloimmunity and Transplantation

Mohammad Afzal Khan
Dong ge Li
Ashling L. Zhang
Alexander S. Krupnick
Christine L. Lau

Frontiers in Immunology

doi 10.3389/fimmu.2025.1685251

1,118 views

Correction

Published on 03 Dec 2025

Correction: Platelet alloimmunization in transfusion-dependent thalassemia patients from Southern China (2014-2023)

in Alloimmunity and Transplantation

Frontiers Production Office

Frontiers in Immunology

doi 10.3389/fimmu.2025.1755852

500 views

Correction

Published on 03 Dec 2025

Correction: Leukocyte dynamics in Cynomolgus monkeys following heterotopic heart allotransplantation under costimulation pathway blockade

in Alloimmunity and Transplantation

Gheorghe Braileanu
Agnes M. Azimzadeh
Tianshu Zhang
Lars Burdorf
Richard N. Pierson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1732897

647 views

Original Research

Published on 02 Dec 2025

Association of HLA-DQA106:01 and DPB105:01:01G alleles with susceptibility to end-stage liver disease with HBV infection in liver transplant recipients from the Zhejiang Han population, China

in Alloimmunity and Transplantation

Genjie Lu
Yanmin He
Yangfang Lu
Wei Chen
Caide Lu
Faming Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1684437

1,331 views

Brief Research Report

Published on 02 Dec 2025

Daratumumab combined with anti-CD20 therapy in pediatric and adult refractory idiopathic nephrotic syndrome: single-center experience

in Alloimmunity and Transplantation

Hamza Naciri Bennani
Thomas Sandaye
Quentin Charroyer
Aurelie Etangsale
Henri Vacher Coponat
Marie Julien
Vincent Mear
Olivier Dunand
Ludovic Di Ascia

Frontiers in Immunology

doi 10.3389/fimmu.2025.1722023

1,278 views

Review

Published on 28 Nov 2025

Effects of heavy metal exposure on kidney transplant recipients: mechanisms and clinical implications for graft failure risk

in Alloimmunity and Transplantation

Shuxin Li
Hongliang Cao
Binbin Wang
Gengchen Huang
Yongliang Qu
Bo Yuan
Wei Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1718695

1,481 views

Original Research

Published on 28 Nov 2025

Donor age as an independent predictor of inferior outcomes after haploidentical hematopoietic cell transplantation in acute myeloid leukemia. Study conducted on behalf of GETH-TC

in Alloimmunity and Transplantation

Daniel Munárriz
Estefanía Pérez-López
Carlos Martín Rodríguez
Marta Luque
Albert Esquirol
Carmen Martín Calvo
Clara Aparicio
Felipe Peña-Muñóz
Inmaculada Heras Fernando
Itziar Oiartzabal Ormtegi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1700463

1,441 views

Editorial

Published on 28 Nov 2025

Editorial: Finding new hope in old treatments: repurposing immunotherapy in transplantation

in Alloimmunity and Transplantation

Yeqi Nian
Jasper Iske
Xiaodong Yuan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1738636

930 views

Editorial

Published on 21 Nov 2025

Editorial: Multi-omics assessment for the discovery of promising novel molecules in the treatment of transplant organ injury

in Alloimmunity and Transplantation

Hao Liu
Xiao-kang Li
Shao-wei Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1744256

676 views

Correction

Published on 21 Nov 2025

Correction: Single-cell transcriptomics unravels the early immune landscape of renal allograft rejection and nominates Ccl3-Ccr5 as a therapeutic target

in Alloimmunity and Transplantation

Fanchao Wei
Zhaoxiang Wang
Ruochen Qi
Jingliang Zhang
Shichao Han
Changhong Shi
Tong Lu
Zhite Zhao
Zhengxuan Li
Lang Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1740964

1,148 views

Original Research

Published on 18 Nov 2025

Allogeneic hematopoietic stem cell transplantation for mixed-phenotype acute leukemia: a single-center study

in Alloimmunity and Transplantation

Mengze Hao
Xiaoli Zhao
Xiaoyu Zhang
Weihua Zhai
Qiaoling Ma
Donglin Yang
Aiming Pang
Sizhou Feng
Yi He
Erlie Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1691762

1,545 views

Case Report

Published on 10 Nov 2025

Case Report: A novel approach to prevent chronic histiocytic intervillositis and recurrent pregnancy loss by targeting maternal alloimmunity

in Alloimmunity and Transplantation

Mathilde Gavillet
Carole Gengler
Helene Legardeur
Monique Gannagé
Jardena Puder
Lydie Beauport
Alice Panchaud
Samuel Rotman
Denis Comte
David Baud

Frontiers in Immunology

doi 10.3389/fimmu.2025.1693016

2,691 views
1 citation

Original Research

Published on 07 Nov 2025

A novel GCGR/GLP-1R dual-agonist TB001 ameliorates kidney fibrosis via inhibiting PERK-mediated endoplasmic reticulum stress pathway

in Alloimmunity and Transplantation

Weijie Lai
Linjie Peng
Jianliang Min
Longhui Qiu
Chang Wang
Shuangjin Yu
Qihao Li
Ruobing Li
Xianxing Jiang
Guodong Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1665860

2,213 views

1,870 articles

articles

Lipocalin-2 modulates recipients alloimmune responses to the murine kidney transplants

The efficacy of extracorporeal photopheresis in the treatment of steroid refractory acute graft-versus-host disease: a systematic review and meta-analysis

Epitope-level analysis of cross-reactive human HLA antibodies against genetically modified swine leukocyte antigens in xenotransplantation

Long-term compromised immune regulation after rituximab induction in blood group incompatible (ABOi) living-donor renal transplantation – 5 year results of a prospective pilot study

Urothelial carcinoma following kidney transplantation: a narrative review of Chinese insights and challenges from pathogenesis to precision diagnosis and treatment

Tertiary lymphoid structure drives allograft rejection via IFN-γ-JAK-STAT-dependent atypical memory B cell differentiation

Recent progress in pig-to-human kidney xenotransplantation

In vitro derivation of megakaryocytes and platelets from induced pluripotent stem cells: developmental foundations and translational perspectives

GJA5 and ATP1A1 perturbations recapitulate inflammation-related beat irregularities in iPSC-based atrial myocardium tissue model

HLA-vaccine transplantations for refractory leukemia: beyond double-unit cord blood

Association of pharmacokinetic biomarkers with early immune recovery following HLA-haploidentical hematopoietic cell transplantation

TSG-6 expression distinguishes rejected and non-rejected human lung transplants: a retrospective study

Correction: Platelet alloimmunization in transfusion-dependent thalassemia patients from Southern China (2014-2023)

Correction: Leukocyte dynamics in Cynomolgus monkeys following heterotopic heart allotransplantation under costimulation pathway blockade

Association of HLA-DQA106:01 and DPB105:01:01G alleles with susceptibility to end-stage liver disease with HBV infection in liver transplant recipients from the Zhejiang Han population, China

Daratumumab combined with anti-CD20 therapy in pediatric and adult refractory idiopathic nephrotic syndrome: single-center experience

Effects of heavy metal exposure on kidney transplant recipients: mechanisms and clinical implications for graft failure risk

Donor age as an independent predictor of inferior outcomes after haploidentical hematopoietic cell transplantation in acute myeloid leukemia. Study conducted on behalf of GETH-TC

Editorial: Finding new hope in old treatments: repurposing immunotherapy in transplantation

Editorial: Multi-omics assessment for the discovery of promising novel molecules in the treatment of transplant organ injury

Correction: Single-cell transcriptomics unravels the early immune landscape of renal allograft rejection and nominates Ccl3-Ccr5 as a therapeutic target

Allogeneic hematopoietic stem cell transplantation for mixed-phenotype acute leukemia: a single-center study

Case Report: A novel approach to prevent chronic histiocytic intervillositis and recurrent pregnancy loss by targeting maternal alloimmunity

A novel GCGR/GLP-1R dual-agonist TB001 ameliorates kidney fibrosis via inhibiting PERK-mediated endoplasmic reticulum stress pathway

articles

Lipocalin-2 modulates recipients alloimmune responses to the murine kidney transplants

The efficacy of extracorporeal photopheresis in the treatment of steroid refractory acute graft-versus-host disease: a systematic review and meta-analysis

Epitope-level analysis of cross-reactive human HLA antibodies against genetically modified swine leukocyte antigens in xenotransplantation

Long-term compromised immune regulation after rituximab induction in blood group incompatible (ABOi) living-donor renal transplantation – 5 year results of a prospective pilot study

Urothelial carcinoma following kidney transplantation: a narrative review of Chinese insights and challenges from pathogenesis to precision diagnosis and treatment

Tertiary lymphoid structure drives allograft rejection via IFN-γ-JAK-STAT-dependent atypical memory B cell differentiation

Recent progress in pig-to-human kidney xenotransplantation

In vitro derivation of megakaryocytes and platelets from induced pluripotent stem cells: developmental foundations and translational perspectives

GJA5 and ATP1A1 perturbations recapitulate inflammation-related beat irregularities in iPSC-based atrial myocardium tissue model

HLA-vaccine transplantations for refractory leukemia: beyond double-unit cord blood

Association of pharmacokinetic biomarkers with early immune recovery following HLA-haploidentical hematopoietic cell transplantation

TSG-6 expression distinguishes rejected and non-rejected human lung transplants: a retrospective study

Correction: Platelet alloimmunization in transfusion-dependent thalassemia patients from Southern China (2014-2023)

Correction: Leukocyte dynamics in Cynomolgus monkeys following heterotopic heart allotransplantation under costimulation pathway blockade

Association of HLA-DQA1*06:01 and DPB1*05:01:01G alleles with susceptibility to end-stage liver disease with HBV infection in liver transplant recipients from the Zhejiang Han population, China

Daratumumab combined with anti-CD20 therapy in pediatric and adult refractory idiopathic nephrotic syndrome: single-center experience

Effects of heavy metal exposure on kidney transplant recipients: mechanisms and clinical implications for graft failure risk

Donor age as an independent predictor of inferior outcomes after haploidentical hematopoietic cell transplantation in acute myeloid leukemia. Study conducted on behalf of GETH-TC

Editorial: Finding new hope in old treatments: repurposing immunotherapy in transplantation

Editorial: Multi-omics assessment for the discovery of promising novel molecules in the treatment of transplant organ injury

Correction: Single-cell transcriptomics unravels the early immune landscape of renal allograft rejection and nominates Ccl3-Ccr5 as a therapeutic target

Allogeneic hematopoietic stem cell transplantation for mixed-phenotype acute leukemia: a single-center study

Case Report: A novel approach to prevent chronic histiocytic intervillositis and recurrent pregnancy loss by targeting maternal alloimmunity

A novel GCGR/GLP-1R dual-agonist TB001 ameliorates kidney fibrosis via inhibiting PERK-mediated endoplasmic reticulum stress pathway

Association of HLA-DQA106:01 and DPB105:01:01G alleles with susceptibility to end-stage liver disease with HBV infection in liver transplant recipients from the Zhejiang Han population, China