Frontiers in Immunology | Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Case Report

Published on 18 Dec 2025

Combined biologic therapy targeting B cells and eosinophils in relapsing multiple sclerosis and severe asthma: a case report of ofatumumab and mepolizumab

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Aurora Zanghì
Paola Sofia Di Filippo
Claudia Rutigliano
Carlo Avolio
Emanuele D’Amico

Frontiers in Immunology

doi 10.3389/fimmu.2025.1634477

Original Research

Published on 18 Dec 2025

Joint association between pan-immune inflammation value and physical pain with self-perception of patients in rheumatoid arthritis: a retrospective cohort study employing traditional statistics and interpretable machine learning

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yang Li
Jian Liu
Yue Sun
Yuedi Hu
Jianting Wen
Xueni Cheng
Shengfeng Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1711081

Review

Published on 18 Dec 2025

Lactylation: the metabolic–immune hub in autoimmune diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Qingqing Xia
Dantong Sun
Ke Wan
Chengcheng Liu
Han Shu
Miao Wang
Tongsheng Zhou
Ying Chen
Xue Yang
Xiao-Feng Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1651923

Original Research

Published on 18 Dec 2025

Serum CHI3L1 levels correlate with disease activity in rheumatoid arthritis and reveal potential molecular mechanisms

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yi Deng
Dan Wang
Chao Wang
Kaiyun Guo
Ming Lei
Yanzhao Huang
Langui Tang
Ya Ding
Yan Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1729989

118 views

Original Research

Published on 18 Dec 2025

Differential expression profiles of lncRNAs and a preliminary study on the mechanism of lncRNA FAM225A in triple seronegative myasthenia gravis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yuehan Hao
Chen Chen
Bo Wang
ChunHua Yang
Ying Zhu
Ruixia Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1664131

Original Research

Accepted on 17 Dec 2025

Efficacy and Safety of Zuberitamab in the Treatment of Primary Membranous Nephropathy: An Observational Study

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Li Zong
Sha Wang
Ke Zhao
Fangyi Lu
Shan-kui Qian
Xiangdong Yang

Frontiers in Immunology

Original Research

Accepted on 17 Dec 2025

IL17-deficient NOD mice are protected from autoimmune diabetes due to decreased antigen presentation and T cell activation

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

James Alexander Pearson
Yangyang Li
Juan Huang
Jian Peng
F. Susan Wong
Li Wen

Frontiers in Immunology

Case Report

Accepted on 17 Dec 2025

Case Report: IgG4-RD-related autoimmune pancreatitis combined with monoclonal gammopathy of undetermined significance

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Jinhu Wei
Xiang Chen
Li Chen
Yao Xie
Wanman Li
Jiyuan Liang

Frontiers in Immunology

Review

Published on 17 Dec 2025

Keratinocytes as active regulators of cutaneous and mucosal immunity: a systematic review across inflammatory epithelial disorders

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Felix J. Klimitz
Yizhuo Shen
Federico Repetto
Stav Brown
Leonard Knoedler
Christine J. Ko
Nebal Abu Hussein
William J. Crisler
Taylor Adams
Naftali Kaminski

Frontiers in Immunology

doi 10.3389/fimmu.2025.1694066

337 views

Correction

Published on 17 Dec 2025

Correction: Coexistence of bullous pemphigoid, intrahepatic cholangiocarcinoma, and alopecia areata: a case report of multifactorial autoimmunity in a surgical context

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Shanlin Li
Ying Wang
Dingquan Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1765423

256 views

Case Report

Published on 17 Dec 2025

Management of alemtuzumab-induced Graves’ disease in pregnancy: a case report and literature review

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Marsida Teliti
Maria Gallo
Pietro Costa
Spyridon Chytiris
Flavia Magri
Mario Rotondi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1722459

174 views

Original Research

Accepted on 16 Dec 2025

The gut microbiota composition is shaped by disease activity and individual treatment responses in patients with multiple sclerosis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Veronika Ticha
Stepan Coufal
Zuzana Jiraskova Zakostelska
Tomas Thon
Radka Roubalova
Tomas Hrncir
Miloslav Kverka
Miluse Pavelcova
Pavlina Kleinova
Jana Lizrova Preiningerova

Frontiers in Immunology

317 views

Review

Accepted on 16 Dec 2025

Aberrant B Cell Responses as Drivers of Autoantibody Generation and Epitope Diversification in SLE Pathogenesis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Fareeha Tariq
Yathavi Charavanmuttu
Kazi Labiba
Chris Wincup

Frontiers in Immunology

Correction

Accepted on 16 Dec 2025

Correction: Case Report: Fecal Microbiota Transplantation via capsules ameliorated clinical outcomes in a patient with Multiple Sclerosis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Luca Masucci
Stefano Bibbò
Flavio De Maio
Fioravante Capone
Gianluca Quaranta
Debora Rondinella
Roberto Rosato
Mauro Minelli
Desy De Lorenzis
MAURIZIO SANGUINETTI

Frontiers in Immunology

Review

Accepted on 16 Dec 2025

The Immunobiology and Therapeutic potential of Regulatory T Cells in Autoimmune Diseases and Allergic Diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Hao-Tao ZENG
Wen-Wen XIE
Jian-Bin HUANG
Yi-Chi ZHOU
Jing-Yi YUAN
Jia-Xue FENG
Xiaohang Shi
Li Tian
Xian-Hai ZENG
Shu-Qi QIU

Frontiers in Immunology

Review

Accepted on 16 Dec 2025

When viral infections meet the anti-MDA5 antibody-positive dermatomyositis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Shuzi Liu
Zheng Zhao
Yabin Li
Yao Tan
Huabin Tian
Xie Fei

Frontiers in Immunology

General Commentary

Published on 16 Dec 2025

Commentary: Targeting fibroblast activation protein in rheumatoid arthritis: from molecular imaging to precision therapeutics

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yaoxin Ao
Jiangfeng Lyu
Junxing Yang
Fangjun Xiao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1653274

212 views

Original Research

Published on 16 Dec 2025

CD48, CD69, and TIGIT as diagnostic biomarkers for primary Sjögren’s syndrome: an integrated machine learning and multi-disease discrimination validation study

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Linlin Xu
Pingping Jiang
Yang Xiao
Hongling Wang
Hongbo Liu
Huoying Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1700831

419 views

Original Research

Published on 16 Dec 2025

The epidemiology and biologics treatment patterns of juvenile idiopathic arthritis in Taiwan- an 8-year follow-up

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Ya-Chiao Hu
Yun-Lin Huang
Szu-Yu Yiao
Min-Ting Lin
Fang-Ju Lin
Yao-Hsu Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1712103

448 views

Correction

Published on 16 Dec 2025

Correction: Obinutuzumab in systemic lupus erythematosus: a real-world experience

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Chunmei Wu
Yinglu Wang
Shenshen Chen
Yanwei Lin
Fang Du
Xiaodong Wang
Sheng Chen
Liangjing Lu
Shuang Ye
Huihua Ding

Frontiers in Immunology

doi 10.3389/fimmu.2025.1764419

222 views

Editorial

Published on 16 Dec 2025

Editorial: Mathematical modeling in discovery and analysis of immune responses

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Penelope A. Morel
Jaroslaw Smieja
Urszula Foryś

Frontiers in Immunology

doi 10.3389/fimmu.2025.1760985

295 views

Original Research

Published on 16 Dec 2025

Antiphospholipid antibodies induce endothelial procoagulant activity and release of extracellular vesicles independently of a second hit

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Daniel Álvarez
Hephzibah E. Winter
Udo R. Markert
Ángela P. Cadavid J.
Diana M. Morales-Prieto

Frontiers in Immunology

doi 10.3389/fimmu.2025.1702103

265 views

Original Research

Published on 16 Dec 2025

S100A8/S100A9 through PAD4 activation of neutrophil extracellular traps promotes granulomatous lobular mastitis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Tingting Zhu
Hao Yu
Wei Wang
Yulu Sun
Shengjia Wang
Dongwen Ma
Yongzhong Yao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1672538

219 views

Case Report

Published on 16 Dec 2025

COVID-19–associated delayed-onset MuSK-positive myasthenia gravis presenting solely with respiratory failure: a case report

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Xiao-Guang Cao
Jun-xi Ni
Xiong-feng Zhu
Hua-dong Meng
Chong-jian Huang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1649930

358 views

1,960 articles

articles

Combined biologic therapy targeting B cells and eosinophils in relapsing multiple sclerosis and severe asthma: a case report of ofatumumab and mepolizumab

Joint association between pan-immune inflammation value and physical pain with self-perception of patients in rheumatoid arthritis: a retrospective cohort study employing traditional statistics and interpretable machine learning

Lactylation: the metabolic–immune hub in autoimmune diseases

Serum CHI3L1 levels correlate with disease activity in rheumatoid arthritis and reveal potential molecular mechanisms

Differential expression profiles of lncRNAs and a preliminary study on the mechanism of lncRNA FAM225A in triple seronegative myasthenia gravis

Efficacy and Safety of Zuberitamab in the Treatment of Primary Membranous Nephropathy: An Observational Study

IL17-deficient NOD mice are protected from autoimmune diabetes due to decreased antigen presentation and T cell activation

Case Report: IgG4-RD-related autoimmune pancreatitis combined with monoclonal gammopathy of undetermined significance

Keratinocytes as active regulators of cutaneous and mucosal immunity: a systematic review across inflammatory epithelial disorders

Correction: Coexistence of bullous pemphigoid, intrahepatic cholangiocarcinoma, and alopecia areata: a case report of multifactorial autoimmunity in a surgical context

Management of alemtuzumab-induced Graves’ disease in pregnancy: a case report and literature review

The gut microbiota composition is shaped by disease activity and individual treatment responses in patients with multiple sclerosis

Aberrant B Cell Responses as Drivers of Autoantibody Generation and Epitope Diversification in SLE Pathogenesis

Correction: Case Report: Fecal Microbiota Transplantation via capsules ameliorated clinical outcomes in a patient with Multiple Sclerosis

The Immunobiology and Therapeutic potential of Regulatory T Cells in Autoimmune Diseases and Allergic Diseases

When viral infections meet the anti-MDA5 antibody-positive dermatomyositis

Commentary: Targeting fibroblast activation protein in rheumatoid arthritis: from molecular imaging to precision therapeutics

CD48, CD69, and TIGIT as diagnostic biomarkers for primary Sjögren’s syndrome: an integrated machine learning and multi-disease discrimination validation study

The epidemiology and biologics treatment patterns of juvenile idiopathic arthritis in Taiwan- an 8-year follow-up

Correction: Obinutuzumab in systemic lupus erythematosus: a real-world experience

Editorial: Mathematical modeling in discovery and analysis of immune responses

Antiphospholipid antibodies induce endothelial procoagulant activity and release of extracellular vesicles independently of a second hit

S100A8/S100A9 through PAD4 activation of neutrophil extracellular traps promotes granulomatous lobular mastitis

COVID-19–associated delayed-onset MuSK-positive myasthenia gravis presenting solely with respiratory failure: a case report