Frontiers in Immunology | Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Original Research

Published on 08 Oct 2025

Pannexin-1 hemichannels promote experimental colitis inflammation in a CD4+ T cell-specific manner

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Pooja Rani Mina
Bruna de Gois Macedo
Caio Loureiro Salgado
Chloe Liliana Leff
Daniel Bihnam
Henrique Borges da Silva

Frontiers in Immunology

doi 10.3389/fimmu.2025.1621353

1,369 views

Mini Review

Published on 08 Oct 2025

Hydroxychloroquine’s diverse targets: a new frontier in precision medicine

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Bin Du
Leqi Li
Jingjing Li
Yiping Liu
Pu Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1655573

1,281 views

Case Report

Published on 08 Oct 2025

Case Report: Novel endoscopic characteristics of early-stage autoimmune gastritis from two cases: the fog is lifting

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yiming Song
Jianing Yan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1550919

979 views

Original Research

Published on 08 Oct 2025

Safety profile of complement C5 inhibitors and FcRn inhibitors in the treatment of myasthenia gravis: analysis of the FAERS database and disease-gene interaction network

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Luqiong Wang
Jiaojiao Chen
Huixiang Li
Lin Wang
Feiyu Liu
Xiaoli Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1667249

4,055 views

Original Research

Published on 08 Oct 2025

Lactobacillus plantarum-derived cytoplasmic membrane vesicles as novel anti-inflammatory nanotherapeutics for psoriasis management

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yuedong Xie
Guowen Lv
Dandan Su
Manchun Li
Quanle Xu
Hongbo Chen
Fang Cheng
Dongling Dai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1647466

2,545 views

Original Research

Published on 08 Oct 2025

The safety profiles of avacopan on microscopic polyangiitis and granulomatosis with polyangiitis: a real-world pharmacovigilance analysis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yang Li
Anna Meng
Yue Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654735

2,698 views

Correction

Published on 08 Oct 2025

Correction: Novel advances on pathophysiological mechanisms, clinical manifestations, and treatment of antiphospholipid syndrome

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Qing-Nan Zhu
Xiang-Bo Qi
Shu-Wei Ren
Yu-Ye Li
Ze-Wen Yan
Yu Sun
Yan Shi
Qing-Si Wen
Mao-Mao Wu
Da-Peng Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1711668

746 views

Editorial

Published on 07 Oct 2025

Editorial: Understanding scleroderma: symptoms, causes, treatment options, and advanced diagnostic techniques

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Predrag Ostojic

Frontiers in Immunology

doi 10.3389/fimmu.2025.1716460

1,094 views

Original Research

Published on 03 Oct 2025

Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology, molecular dynamics, and experimental validation

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Haotian Li
Congmin Xia
Yuewei Song
Jin Chen
Yanjun Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1675429

3,810 views
1 citation

Review

Published on 03 Oct 2025

ECM remodeling in hypothyroidism-associated MAFLD: mechanisms, clinical relevance, and therapeutic targets

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Tianzhen Wang
Liyun Duan
Beiying Zhao
Jingbin Zhang
Yongjiang Yu
Jinyue Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639196

2,320 views

Case Report

Published on 02 Oct 2025

Efgartigimod for patients with thymoma associated generalized myasthenia gravis during the perioperative period: a four-case report

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Liuli Ren
Ling Wei
Song Jiang
Hongru Li
Anguo Chen
Juanjuan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1627584

3,424 views

Original Research

Published on 02 Oct 2025

Comprehensive disproportionality analysis of individual case safety reports associated with Janus kinase inhibitors in psoriasis and psoriatic arthritis using the FAERS database

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Kunhong Deng
Han Jiang
Shan Xie
Minghui Yin
Chengjun Guo
Longjian Huang
Junlong Ma
Yun Kuang
Yuxia Xiang
Chengxian Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629886

2,665 views
1 citation

Original Research

Published on 02 Oct 2025

Gene variants of glucocorticoid activation pathways and the outcomes of patients with Takayasu arteritis – a retrospective cohort study

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Faustino Peron Filho
Andressa de Souza Moreira
Eduarda Bonelli Zarur
Gerson Dierley Keppeke
Alexandre Wagner Silva de Souza

Frontiers in Immunology

doi 10.3389/fimmu.2025.1675026

1,101 views

Original Research

Published on 02 Oct 2025

MFAP5 as a promising biomarker for connective tissue disease-associated interstitial lung disease

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yufang Dai
Jiaqian Zhang
Xiufeng Bai
Shasha Wu
Yanqiong Chen
Dachao Mou
Yun Wang
Yunlong Zhu
Yi Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1642408

1,997 views

Review

Published on 02 Oct 2025

Research progress on traditional Chinese medicine compounds in autoimmune-related skin diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yuhan Wang
Pengzhi Bu
Yu Deng
Wenyingzi Zhao
Guangtao Pan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629288

5,182 views

Case Report

Published on 01 Oct 2025

Case Report: Autoimmune glial fibrillary acidic protein astrocytopathy complicated with Sjogren’s syndrome and recurrent respiratory failure

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Po-You Chen
Tzu-Han Lee
Wan-Lun Tsai
Hua-Ren Chang
Kuo-Sen Tseng
Cheng-Che Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1669415

1,519 views

Opinion

Published on 01 Oct 2025

Macrophage subtypes and pathways in autoimmune interstitial lung diseases: potential therapeutic targets

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Richa Tyagi
Surya Kant

Frontiers in Immunology

doi 10.3389/fimmu.2025.1638345

1,382 views

Review

Published on 01 Oct 2025

Shared immunological pathways in rheumatoid arthritis-related interstitial lung disease

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Jingyi Xu
Changhong Li
Jinxia Zhao
Rong Mu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1630729

2,804 views

Original Research

Published on 01 Oct 2025

Impact of the prognostic nutritional index on the recompensation of patients with decompensated primary biliary cholangitis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Chunjiao Yu
Fan Ni
Mengyao Zheng
Zhaoda Duan
Wenjie Yang
Man Huang
Hongyan Xu
Mengyu Li
Shunyu Chen
Chaozhang Gu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1605380

1,627 views

Case Report

Published on 01 Oct 2025

Case report: Spontaneous remission of severe aplastic anemia mediated by mutant hematopoietic stem cells evading T-cell attack

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Kohei Shiroshita
Yoshitaka Zaimoku
Himari Kudo
Naoshi Obara
Kazuyoshi Hosomichi
Yui Kano
Miku Kobayashi
Eriko Morishita
Hiroyuki Takamatsu
Takaaki Toyama

Frontiers in Immunology

doi 10.3389/fimmu.2025.1635943

2,119 views

Original Research

Published on 30 Sep 2025

CLEC4E as a molecular biomarker in systemic lupus erythematosus: integrating bioinformatics and clinical data to assess its prognostic value

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Xiaoxia Ma
Huan Zhang
Jiana Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1617878

1,805 views

Original Research

Published on 30 Sep 2025

Impact of telitacicept on gonadal function in adult female patients with systemic lupus erythematosus: a prospective cohort study

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Ziyan Zhang
Qianni Zeng
Yabin Wen
Yuqing Zhou
Lihua Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610136

1,550 views

Original Research

Published on 30 Sep 2025

NLR (neutrophil to lymphocyte ratio), PLR (platelet to lymphocyte ratio), and SII (systemic immune-inflammation index) reflect disease activity and renal remission in patients with lupus nephritis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Xiaohui Zhang
Yuan Chen
Yong Fan
Dai Gao
Zhuoli Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646276

2,084 views

Original Research

Published on 30 Sep 2025

RIPK3 impacts antibody generation in an induced model of murine lupus through mechanisms other than necroptosis and antigen presentation

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Céleste Pilon
Elena Lonina
Jerrold S. Levine
Sylvie Lesage
Joyce Rauch

Frontiers in Immunology

doi 10.3389/fimmu.2025.1506124

1,873 views

1,977 articles

articles

Pannexin-1 hemichannels promote experimental colitis inflammation in a CD4+ T cell-specific manner

Hydroxychloroquine’s diverse targets: a new frontier in precision medicine

Case Report: Novel endoscopic characteristics of early-stage autoimmune gastritis from two cases: the fog is lifting

Safety profile of complement C5 inhibitors and FcRn inhibitors in the treatment of myasthenia gravis: analysis of the FAERS database and disease-gene interaction network

Lactobacillus plantarum-derived cytoplasmic membrane vesicles as novel anti-inflammatory nanotherapeutics for psoriasis management

The safety profiles of avacopan on microscopic polyangiitis and granulomatosis with polyangiitis: a real-world pharmacovigilance analysis

Correction: Novel advances on pathophysiological mechanisms, clinical manifestations, and treatment of antiphospholipid syndrome

Editorial: Understanding scleroderma: symptoms, causes, treatment options, and advanced diagnostic techniques

Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology, molecular dynamics, and experimental validation

ECM remodeling in hypothyroidism-associated MAFLD: mechanisms, clinical relevance, and therapeutic targets

Efgartigimod for patients with thymoma associated generalized myasthenia gravis during the perioperative period: a four-case report

Comprehensive disproportionality analysis of individual case safety reports associated with Janus kinase inhibitors in psoriasis and psoriatic arthritis using the FAERS database

Gene variants of glucocorticoid activation pathways and the outcomes of patients with Takayasu arteritis – a retrospective cohort study

MFAP5 as a promising biomarker for connective tissue disease-associated interstitial lung disease

Research progress on traditional Chinese medicine compounds in autoimmune-related skin diseases

Case Report: Autoimmune glial fibrillary acidic protein astrocytopathy complicated with Sjogren’s syndrome and recurrent respiratory failure

Macrophage subtypes and pathways in autoimmune interstitial lung diseases: potential therapeutic targets

Shared immunological pathways in rheumatoid arthritis-related interstitial lung disease

Impact of the prognostic nutritional index on the recompensation of patients with decompensated primary biliary cholangitis

Case report: Spontaneous remission of severe aplastic anemia mediated by mutant hematopoietic stem cells evading T-cell attack

CLEC4E as a molecular biomarker in systemic lupus erythematosus: integrating bioinformatics and clinical data to assess its prognostic value

Impact of telitacicept on gonadal function in adult female patients with systemic lupus erythematosus: a prospective cohort study

NLR (neutrophil to lymphocyte ratio), PLR (platelet to lymphocyte ratio), and SII (systemic immune-inflammation index) reflect disease activity and renal remission in patients with lupus nephritis

RIPK3 impacts antibody generation in an induced model of murine lupus through mechanisms other than necroptosis and antigen presentation