Frontiers in Immunology | Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Original Research

Published on 29 Sep 2025

Impact of Sjögren’s disease and its immunological characteristics on reaching remission or low disease activity state in systemic lupus erythematosus patients: a propensity score-matched longitudinal study

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Haoze Zhang
Huijuan Zhang
Dai Gao
Lanlan Ji
Yanjie Hao
Zhuoli Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639252

1,596 views

Case Report

Published on 29 Sep 2025

Case Report: Behçet’s syndrome and venous thrombosis in children: a case study and review of the literature

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Qinan Yin
Yuan Bian
Fang Niu
Mao Zhang
Siyu Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1664004

1,884 views

Review

Published on 29 Sep 2025

Common pathological mechanisms and therapeutic strategies in primary Sjogren’s syndrome and primary biliary cholangitis: from tissue immune microenvironment to targeted therapy

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Keying Ye
Xinyi Yao
Dingqi Lu
Chenfei Tan
Xinchang Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1620073

2,454 views

Original Research

Published on 26 Sep 2025

HuR ablation destabilizes Foxp3 mRNA and impairs regulatory T cell function, contributing to an autoimmune phenotype

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Fatemeh Fattahi
Jason S. Ellis
Laura Vallance
Kristin Bahleda
Julia Holden
Sarah Socha
Joshua Meier
Francisco Gomez-Rivera
Ulus Atasoy

Frontiers in Immunology

doi 10.3389/fimmu.2025.1618677

2,502 views

Case Report

Published on 26 Sep 2025

Case Report: Occupational bullous dermatosis: first report of skin lesions induced by PVC welding fume in a manufacturing worker

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Angela Stufano
Piero Lovreglio
Gerardo Cazzato
Paolo Danza
Riccardo Ravallese
Nicoletta Cassano
Gino Antonio Vena
Francesca Ambrogio
Benedetta Tirone
Caterina Foti

Frontiers in Immunology

doi 10.3389/fimmu.2025.1648829

1,271 views

Review

Published on 26 Sep 2025

A comparative review of myocarditis in pediatrics versus adults: pathogenesis, diagnosis, and management

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Jacob C. Ricci
Nick A. Farahani
Cormac J. Davis
Kyra G. Ritter
Lauren M. Parrow
Priya I. Tomerlin
Ashley A. Darakjian
Katherine Gegoutchadze
Dipankar Gupta
Katelyn A. Bruno

Frontiers in Immunology

doi 10.3389/fimmu.2025.1601307

3,141 views

Brief Research Report

Published on 25 Sep 2025

Introducing human 3D skin models as a new serological diagnostic tool for severe autoimmune bullous diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Laura Huth
Ruth Heise
Yvonne Marquardt
Manuela Jansen
David Kluwig
Morna Friederike Schmidt
Nicole Albuscheit
Verena von Felbert
CTC-A Translation Group
Stefan Jockenhoevel

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661851

1,717 views

Case Report

Published on 25 Sep 2025

Dupilumab treatment for Chinese Nagashima-type palmoplantar keratoderma associated with atopic dermatitis: a case report

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Chunting Hua
Hao Cheng
Xianzhen Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1647441

1,262 views

Original Research

Published on 25 Sep 2025

Clinical and immunological characterization of a Netherton syndrome infant with a large SPINK gene cluster deletion and a c.1258A>G polymorphism in SPINK5

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yaning Guan
Qian Li
Yongjing Liu
Pingping Zhang
Maolin Huang
Yimin Guo
Jing Chen
Yan Chen
Zuochen Du
Pei Huang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1658444

1,499 views

Original Research

Published on 25 Sep 2025

Soluble checkpoint molecules as predictive biomarker for disease activity and long-term outcome in SLE

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Léa-Sophie Dreveton
Jakob Joachim Spencker
Hector Rincon-Arevalo
Arman Aue
Bilgin Osmanodja
Annika Wiedemann
Franziska Szelinski
Gerhard Krönke
Thomas Dörner
Eva Schrezenmeier

Frontiers in Immunology

doi 10.3389/fimmu.2025.1685275

1,502 views

Review

Published on 25 Sep 2025

Systemic dysregulation of the gut microenvironment plays a pivotal role in the onset and progression of inflammatory bowel disease

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Ruilong Kou
Yonggang Guo
Zhiwei Qin
Xiaochen Xu
Yihao Liu
Wenqin Wei
Yu Chen
Zhiyuan Jian
Bin Lan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661386

2,304 views

Brief Research Report

Published on 25 Sep 2025

Autoantibody production in pregnancy: relationship with mRNA BNT162b2 immunization, active COVID-19, and pre-eclampsia

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Mauro César da Silva
George Tadeu Nunes Diniz
Maria Júlia da Silva Correia
Neila Caroline Henrique da Silva
Camila Rodrigues de Melo Barbosa
Ana Laura Carneiro Gomes Ferreira
Maria Inês Bezerra de Melo
Jurandy Júnior Ferraz de Magalhães
Eduardo Antônio Donadi
Ariani Impieri Souza

Frontiers in Immunology

doi 10.3389/fimmu.2025.1613088

1,554 views
1 citation

Original Research

Published on 22 Sep 2025

Long-term outcomes of aortic valve insufficiency in patients with Takayasu arteritis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Feyyaz Hazar Yağmur
Muhammet Emin Kutu
Fatih Tastekin
Aysegul Avcu
Senar Şan
Tuğba Ocak
Fatih Yıldırım
Hasan Kocaayan
Safiye Bakkal
Sema Işık

Frontiers in Immunology

doi 10.3389/fimmu.2025.1667603

2,794 views

Review

Published on 22 Sep 2025

STING pathways and Sjögren’s syndrome: Exploration from mechanism to treatment

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yuxiu Ka
Tingting Tan
Yihua Fan
Wei Liu
Aihua Wang
Wen Wang
Gesang Yuzhen
JingYi Zhang
Xiaoge Yao
Xueying Lin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1649046

3,273 views

Review

Published on 22 Sep 2025

The regulatory mechanisms and treatment of HDAC6 in immune dysregulation diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yanyang Liang
Ying Wang
Jianxiao Xing
Junqin Li
Kaiming Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1653588

2,913 views

Review

Published on 22 Sep 2025

Biomarkers in ANCA associated vasculitis: clinical utility, pitfalls and their role in the outcomes assessment

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Chiara Marvisi
Caterina Ricordi
Cecilia Catellani
Stefania Croci
Francesco Muratore
Carlo Salvarani

Frontiers in Immunology

doi 10.3389/fimmu.2025.1616837

2,917 views
1 citation

Original Research

Published on 22 Sep 2025

Changes in T lymphocyte subsets in patients with acute neuromyelitis optica spectrum disorder

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Ying-Zhe Shao
Tao-Feng Tan
Lin-Jie Zhang
Ning Zhao
Li Yang
Qiu-Xia Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654533

2,055 views

Original Research

Published on 22 Sep 2025

TAGAP restrains myeloid and T cell activation in inflammatory bowel disease

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Rui-Ci Lin
Zhifei Shao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1641365

1,997 views

Original Research

Published on 19 Sep 2025

Dysregulated NK cell activation and myeloid-lymphoid imbalance underpin COPD progression: insights from high-dimensional immune profiling and smoking-induced immune remodeling

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Qin Qiao
Yazheng Yang
Ke Huang
Hongtao Niu
Xiaoxia Ren
Shiwei Qumu
Wei Li
Chen Dong
Ting Yang
Ling Ni

Frontiers in Immunology

doi 10.3389/fimmu.2025.1623319

2,647 views

Review

Published on 18 Sep 2025

Antineutrophil cytoplasmic antibody-associated vasculitis: insights into relapse risk and future management directions

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Federico Alberici
Oliver Flossmann
Peter Lamprecht
Kevin W. Loudon
Roberto Padoan
Tamara Popov
Carlo Salvarani
Aladdin J. Mohammad

Frontiers in Immunology

doi 10.3389/fimmu.2025.1655326

3,065 views
2 citations

Review

Published on 18 Sep 2025

CAR-based cell therapy for autoimmune diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Xiu Li
Chao He
Ke Wang
Guo-Ying Xu
Ya-Chao Xie
Xin-Yu Ying

Frontiers in Immunology

doi 10.3389/fimmu.2025.1613622

4,912 views
1 citation

Case Report

Published on 17 Sep 2025

Case Report: Atypical anti-GBM nephritis coexisting with Henoch-Schönlein purpura nephritis: exploring the pathogenic nexus

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yongxiu Huang
Caihong Liu
Wei Wei
Yanbin Lin
Sirong Tao
Yuliang Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1641090

1,554 views

Original Research

Published on 17 Sep 2025

Neutrophil-to-albumin ratio: a novel predictor of osteoporosis in rheumatoid arthritis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yifang Zhang
Zhongyu He
Kaiqiang Li
Qiuping Wu
Shigang Wang
Minying Liu
Qingping Liu
Qiang Xu
Xiangying Kong
Changsong Lin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1666884

2,778 views

Review

Published on 17 Sep 2025

Innovations in immunotherapy for autoimmune diseases: recent breakthroughs and future directions

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

May A. Alsayb

Frontiers in Immunology

doi 10.3389/fimmu.2025.1647066

6,840 views
2 citations

1,977 articles

articles

Impact of Sjögren’s disease and its immunological characteristics on reaching remission or low disease activity state in systemic lupus erythematosus patients: a propensity score-matched longitudinal study

Case Report: Behçet’s syndrome and venous thrombosis in children: a case study and review of the literature

Common pathological mechanisms and therapeutic strategies in primary Sjogren’s syndrome and primary biliary cholangitis: from tissue immune microenvironment to targeted therapy

HuR ablation destabilizes Foxp3 mRNA and impairs regulatory T cell function, contributing to an autoimmune phenotype

Case Report: Occupational bullous dermatosis: first report of skin lesions induced by PVC welding fume in a manufacturing worker

A comparative review of myocarditis in pediatrics versus adults: pathogenesis, diagnosis, and management

Introducing human 3D skin models as a new serological diagnostic tool for severe autoimmune bullous diseases

Dupilumab treatment for Chinese Nagashima-type palmoplantar keratoderma associated with atopic dermatitis: a case report

Clinical and immunological characterization of a Netherton syndrome infant with a large SPINK gene cluster deletion and a c.1258A>G polymorphism in SPINK5

Soluble checkpoint molecules as predictive biomarker for disease activity and long-term outcome in SLE

Systemic dysregulation of the gut microenvironment plays a pivotal role in the onset and progression of inflammatory bowel disease

Autoantibody production in pregnancy: relationship with mRNA BNT162b2 immunization, active COVID-19, and pre-eclampsia

Long-term outcomes of aortic valve insufficiency in patients with Takayasu arteritis

STING pathways and Sjögren’s syndrome: Exploration from mechanism to treatment

The regulatory mechanisms and treatment of HDAC6 in immune dysregulation diseases

Biomarkers in ANCA associated vasculitis: clinical utility, pitfalls and their role in the outcomes assessment

Changes in T lymphocyte subsets in patients with acute neuromyelitis optica spectrum disorder

TAGAP restrains myeloid and T cell activation in inflammatory bowel disease

Dysregulated NK cell activation and myeloid-lymphoid imbalance underpin COPD progression: insights from high-dimensional immune profiling and smoking-induced immune remodeling

Antineutrophil cytoplasmic antibody-associated vasculitis: insights into relapse risk and future management directions

CAR-based cell therapy for autoimmune diseases

Case Report: Atypical anti-GBM nephritis coexisting with Henoch-Schönlein purpura nephritis: exploring the pathogenic nexus

Neutrophil-to-albumin ratio: a novel predictor of osteoporosis in rheumatoid arthritis

Innovations in immunotherapy for autoimmune diseases: recent breakthroughs and future directions